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3 articles for “Toxin neutralization.”
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Antivirulence Therapy- A Promising Alternative Technique for Antibiotic Resistance
Abstract: Antibiotic resistance is increasing at an alarming rate. Over the years there has been a steep rise in number of antibiotic resistant bacteria. This in turn has led to a dip in overall efficacy of a wide range of antibiotics. The last new class of antibiotics was introduced in 2003, but after that there has not been any significant discovery in this area. To overcome this problem of antibiotic resistance …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 7, Issue 3, 2020 · pp. 1–14 Read article
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Production of Single-domain Antibodies Library by Phage Display Technology
Abstract: Single-domain antibodies (dAbs) are synthesized from variable domain gene-segments of atypical camelid or shark “heavy chain antibodies” (HCAbs) by phage display technology. We have constructed a phage display library of > 5 × 107 dAb clones derived from HCAb genes in B lymphocyte repertoire of a lipopolysaccharide (LPS)-immunized Indian desert camel and isolated dAb-phage clones by panning of the library against LPS and Staphylococcus aureus exotoxins. Nucleotide and deduced amino-acid …
Published in Research and Reviews : A Journal of Immunology · Vol. 2, Issue 3, 2012 · pp. 8–13 Read article
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Virulence Factors in pathogens :mechanisms of infection & disease progression
Abstract: Pathogens, like bacteria, viruses, fungi, and parasites, have evolved specialized tools – known as virulence factors – that help them infect hosts, escape the immune system, and cause disease. These factors play a key role in determining how severe an infection becomes, how quickly it spreads, and how the body responds. Some pathogens use adhesins to stick to host cells, while others produce toxins that damage tissues or disrupt normal …
Published in International Journal of Pathogens · Vol. 2, Issue 1, 2025 · pp. 6–11 Read article