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5 articles for “TPP”
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Synthesis and Characterization of PF-127 Stabilized Metformin Encapsulated Chitosan-TPP Nanoparticles
Abstract: Metformin is widely used to manage Type 2 Diabetes, but its effectiveness is limited by low intestinal absorption, high dose requirements, and a short half-life. To tackle these challenges, several nano-drug delivery systems have been designed to optimize the delivery of metformin and enhance its therapeutic efficacy. Nanoparticles (NPs) have emerged as key players in medicine, biology, and pharmacology, gaini considerable attention for their potential applications. Polymeric NPs are among …
Published in Nano Trends – A Journal of Nano Technology & Its Applications · Vol. 27, Issue 1, 2025 · pp. 34–38 Read article
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An Extensive In vitro Approach in Development of Next Generation Drugs Against Trehalose-6-Phosphate Phosphatases Involved in Pathogenicity of Many Microorganisms
Abstract: Normal 0 false false false EN-IN X-NONE X-NONE MicrosoftInternetExplorer4 AbstractTrehalose-6-phosphate phosphatase (TPP) enzymes implicated in pathogenecity of number of bacteria, fungi and nematodes causing serious diseases such as tuberculosis, candedemias, aspergillosis, elephantiasis and parasitic ones. This study is an effort to target a common pathway critical to pathogenicity of different microbes but entirely absent in vertebrates and to come out with new generation drugs by an extensive in vitro approach. …
Published in Research & Reviews : Journal of Herbal Science · Vol. 7, Issue 1, 2018 · pp. 32–43 Read article
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Solution of Solid Traveling Purchaser Problem Using Efficient Genetic Algorithm with Probabilistic Selection and Multi-Parent Crossover Technique
Abstract: In this paper, I design a NP-hard optimization problem and solve this problem by developing a nature-based multi-parent crossover in genetic algorithm (GA). Initially, taking a set of markets, a depot and some products for each of which a positive demand is specified. Purchaser can purchase each product from a subset of markets only a given quantity, less than or equal to the required one, can be purchased at a …
Published in Research & Reviews: Discrete Mathematical Structures · Vol. 5, Issue 3, 2018 · pp. 20–26 Read article
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Modification of Ashaka and Tango Bentonites with Tetraphenyl Phosphonium and Hexadecyl Pyridinium Bromides for Possible Use in Polymer-Clay Nanocomposite Preparation
Abstract: Bentonites from Ashaka (GA) and Tango (GT) of Gombe State, Nigeria were surface modified with Tetraphenyl phosphonium (TPP) and Hexadecyl pyridinium bromides (HDP) by cation exchange method for their possible use in Clay/polymer nanocomposite preparation. The surfaces of the modified products were characterized by means of spectroscopic, diffraction and scanning methods [Fourier-transformed infrared spectroscopy (FTIR), X-ray diffraction (XRD) and scanning electron microscopy (SEM)]. The basal spacing of the unmodified bentonite …
Published in Nano Trends – A Journal of Nano Technology & Its Applications · Vol. 22, Issue 2, 2020 · pp. 15–22 Read article
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Chitosan-conjugated GnRH Nanoparticles with AFM Appearance
Abstract: Nanotechnology can provide new tools for molecular and cellular biology, biotechnology, veterinary physiology, reproduction, detection of pathogens and many more. There are several areas such as science, engineering of agriculture, animal and food systems where nanotechnology could be applied. Application of nanotechnology can be employed in the development of sustained release systems of molecules such as hormones, vitamins, antibiotics, antioxidants and nucleic acids. Longer lasting surges in Gonadotropin hormone (GtH) …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 8, Issue 3, 2019 · pp. 3–5 Read article