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5 articles for “Seizures receptor”
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Elementary Mechanisms and Therapeutic Approaches for Epilepsy: A Neurodegenerative Impairment
Abstract: The main reason of the epilepsy is both genetic as well as acquired sources. Conventionally developed origins comprise thoughtful brain trauma and difficulties consequential from aforementioned infection. Mostly, the reason of epilepsy is not clear. Seizures may also transpire as a moment of additional health complications, like stroke, head injury, toxic assimilation, or metabolic delinquent. Epilepsy is treacherous when seizure befalls throughout pregnancy. Convinced anti-epileptic medicines upsurge the jeopardy of …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 13, Issue 1, 2023 · pp. 41–46 Read article
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Molecular Docking studies of Benzodiazepine Derivatives With GABA(B) Receptor
Abstract: Benzodiazepines (BZDs) are pharmacologically significant compounds that act by binding to GABA A neurotransmitter receptors, subsequently augmenting GABA-induced chloride ion flux, consequently inducing neuronal hyperpolarization. Benzodiazepines are commonly used in the treatment of sleep disorders, anxiety, muscle spasms, seizure disorders, and some forms of depression. The primary inhibitory neurotransmitter, GABA, functions on two types of receptors: the ligand-gated GABA A/C receptors and the G protein-coupled GABA B receptors. These neurotransmitters …
Published in International Journal of Toxins and Toxics · Vol. 1, Issue 2, 2024 · pp. 1–14 Read article
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An Emerging Cause of Treatable Encephalitis: A Case of Anti-NMDA receptor (NMDAR) Encephalitis
Abstract: Anti-NMDA Receptor encephalitis is the most common type of autoimmune limbic encephalitis known. It is characterised by sub-acute onset of psychiatric symptoms along with refractory epilepsy, orofacial and limb dyskinesia and dysautonomia. High clinical suspicion and appropriate antibody testing in cerebrospinal fluid (CSF) and serum is required for early diagnosis and initiation of immunotherapy. Delay in treatment may lead to significant permanent neuro-deficits as well as mortality. Here, we present …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 7, Issue 3, 2017 · pp. 8–11 Read article
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Neurological Manifestations of COVID 19 infection-An Update
Abstract: AbstractThis article focuses on the neurological disorders related to Covid 19 infection based on studies reported from china, Italy and other countries. The virus attaches to the Angiotensin Converting enzyme Receptor which is widely distributed in the body including nervous system. Virus can effected the nervous system by direct neurotropic effects, Immune mediated damage or due to secondary involvement as a part of multi organ dysfunction. Covid 19 Infection is …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 10, Issue 2, 2020 · pp. 7–11 Read article
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Pharmacological Review On Enzalutamide
Abstract: A key therapeutic option in the treatment of prostate cancer, especially metastatic castration-resistant prostate cancer (mCRPC), is Enzalutamide, a second-generation anti androgen drug. Enzalutamide, discovered by Charles Sawyer and Michael Jung at the University of California, Los Angeles, was developed and Food and Drug Administration (FDA)-approved in 2012. Its therapeutic significance was further solidified with subsequent extensions in indications to encompass metastatic castration-sensitive prostate cancer and non-metastatic castration-resistant prostate cancer. …
Published in Trends in Drug Delivery · Vol. 11, Issue 2, 2024 · pp. 7–15 Read article