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2 articles for “Repurposing SARS CoV-2”
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A Review on Repurposing Drugs for Treatment of Covid-19
Abstract: The newly emerged 2019 novel coronavirus is named as severe acute respiratory syndrome 2(SARS CoV-2). Till date, 1,757,393 cases have been observed in India and 37,452 deaths. COVID-19 has been now declared as pandemic and new treatments are urgently needed as we enter a phase beyond containment. In the absence of approved marketed drugs against coronavirus, the treatment and management of novel COVID-19 disease worldwide is a challenge. Developing new …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 7, Issue 3, 2020 · pp. 16–22 Read article
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In Silico Identification of Small Molecules as Novel Coronavirus Protease Enzyme Inhibitors
Abstract: AbstractThe novel corona virus 2019 (COVID-19) is one of the global threats to the human civilization as it causes serious respiratory infection and multi-organ failure. Because of the absence of appropriate treatment protocol for 2019 novel corona virus, different methodologies are being tried in China, including drug repurposing. Recent discovery revealed the structure of novel corona virus main protease enzyme (Mpro) containing HIS41 and CYS145 amino acid residues present in …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 7, Issue 2, 2020 · pp. 33–43 Read article