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13 articles for “P. falciparum”
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Distribution and Prevalence of P. falciparum and P. vivax in and Around Tepi Town in the Year 2003 and 2004 E.C.
Abstract: Malaria is caused from infection by the protozoa of plasmodium. It is one of the serious diseases. There are four species of plasmodium infecting humans; these are Plasmodium falciparum, Plasmodium vivax, Plasmodium ovale, and Plasmodium malaria. The main point of the study of malaria tosses the distribution and prevalence of P. falciparum and P. vivax species in and around Tepi town in the year 2003 and 2004 E.C. The secondary …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 6, Issue 1, 2016 · pp. 1–8 Read article
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Characterization and Variation of Plasmodium falciparum based on small subunit ribosomal RNA gene obtained from HIV sero-positive Patients
Abstract: The development of resistance to ACTS has been shown by several studies to precipitate from multiple strains of P. falciparum. Development drug sensitive P. falciparum has hindered the increase of and transmission of drug resistant P. falciparum. Despite the contribution of about 90% global malaria deaths by high transmission zones like Sub-Saharan Africa, emergence of resistance to anti-malaria drugs has been shown to emanate from low transmission zones like South …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 9, Issue 1, 2022 · pp. 33–42 Read article
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Amplification and in silico Study of Plasmodium vivax and Plasmodium falciparum LDH Gene
Abstract: Several arsenal as well as quinolone drugs are available for treatment of malaria; still it remains a worldwide public health problem. Malarial parasite quickly develops resistance under selective drug pressure. Hence, we require an array of new drugs for malaria treatment. Lactate dehydrogenase (LDH) is an essential enzyme for Plasmodia as they lack functional Krebs cycle in some stages of their lifecycle and thereby prove to be good targets for …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 2, Issue 3, 2012 · pp. 1–5 Read article
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Assessment of Malaria Prevalence and Evaluation of Therapeutic Efficacy of Artemether/Lumefantrine (Coartem®) against Uncomplicated Falciparum Malaria in Wondogenet Woreda, SNNPR, Ethiopia
Abstract: Normal 0 false false false EN-US X-NONE X-NONE AbstractThe study was conducted to assess malaria prevalence and to evaluate therapeutic efficacy of Coartem® for the treatment of uncomplicated falciparum malaria in Wondogenet Woreda, Sidama Zone, Ethiopia. Since the spread of Plasmodium falciparum, parasite resistance to almost all antimalarial monotherapies is a serious impediment to malaria control. Artemether-lumefantrine (Coartem®) therapy has been in use as the first-line treatment for uncomplicated falciparum …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 5, Issue 2, 2015 · pp. 26–34 Read article
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Thrombocytopenia as an Indicator of Malaria
Abstract: Malaria remains today one of the major health problems in most parts of India with increased morbidity and mortality.Low platelet count is regularly related to malaria and has been describing by numerous workers. Thrombocytopenia is a routine characteristic of severe malaria and happens in both P. falciparum and P. vivax disease regardless of the acuteness of infection. The study was conducted in the population of Nadiyad city, and district Kheda …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 8, Issue 3, 2019 · pp. 1–3 Read article
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Trends of Antimalarial Resistance in Ethiopia and its Challenge on Malaria Control Program
Abstract: Antimalarial drugs resistance is one of the major obstacles for malaria control and curtails the life-span of several drugs. Resistance to well tolerated and effective antimalarial drugs such chloroquine and sulfadoxine-pyrimethamine (SP) has forced the switch of national policies to artemisinin-based combination therapy (ACT) for the treatment of falciparum malaria. The emergence of less sensitive clones of Plasmodium falciparum to the ACT drugs, shortly after its deployment, has posed a …
Published in Research and Reviews: A Journal of Medicine · Vol. 6, Issue 1, 2016 · pp. 38–44 Read article
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A Cross-Sectional Study on Prevalence and Seasonal Trends of Malaria and Dengue and Their Co-infection in Patients with Acute Febrile Illness Attending a Tertiary Care Hospital in Jhalawar, Rajasthan
Abstract: Unknown etiologies behind acute febrile illnesses make treatment choices tough for clinicians resulting high mortality rates amongst the vulnerable populations. Vector borne diseases viz. malaria and dengue are the major stake holders responsible for AFI. Determination of their individual as well as concurrent prevalence is important for disease control. The present study aimed to determine the prevalence and seasonality of malaria and dengue and their co infection in acute undifferentiated …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 7, Issue 1, 2017 · pp. 9–14 Read article
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Malaria Parasite Detection in Thin Blood Smear Images Using Deep Learning
Abstract: Algorithms in deep neural networks are being used to show the presence of malaria and to estimate the depth of infection by automatically counting individual uninfected and infected RBCs in images of thin blood smears. During the training period, the relationship was tried on a set of 13600 images from several thin blood spreads and experiment was conducted. My dataset is divided into 80% for training and 20% for testing. …
Published in Journal of Artificial Intelligence Research & Advances · Vol. 7, Issue 1, 2020 · pp. 28–32 Read article
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Pf Phosphatidylserine decarboxylase: Molecular modeling and inhibithors prediction
Abstract: Plasmodium falciparum (P.f) is a protozoan parasite responsible for the most severe and deadly form of malaria. The resistance of Pf to last resort antimalarial drugs has been reported, there is an urgent need to identify new therapeutic candidates for drug development. Advancements in bioinformatics technologies provide potential cost and time-effective solutions for predicting therapeutic candidates. Phosphatidylserine decarboxylase (PSD) is a member of the lyase family (more specifically, the carboxy-lyases), …
Published in Research and Reviews : Journal of Computational Biology · Vol. 12, Issue 2, 2023 · pp. 60–78 Read article
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A Review on the Evidence Base on the Management of Malaria
Abstract: Malaria has been one of the most important infectious diseases of humans for millennia. An estimated 3.3 billion people approximately one-half of the world’s population living in 109 countries—are at risk of contracting this serious and of ten life-threatening diseases. In India the National Malaria Eradication Programme (NMEP), started in 1956, achieved near complete disappearance of the disease in 1960s (from 75 million in 1950s to 0.1 million in 1960s). …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 9, Issue 1, 2019 · pp. 1–11 Read article
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Clinical Profile of Dengue Fever with Its Acute Complications in Rural Population of Jaipur District
Abstract: Dengue is the most important mosquito-borne viral infection in terms of morbidity and mortality. In recent years, it has become a major public health concern. The present study was conducted on hospitalized adult patients of NIMS Medical College & Hospital with the aim to study the clinical profile and usual presentations of dengue fever. During the study of 75 patients of dengue infection, 18 had dengue fever (DF), 19 had …
Published in Research and Reviews: A Journal of Medicine · Vol. 4, Issue 1, 2014 · pp. 12–23 Read article
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Study of Variation in Platelet Count and WBC Count in Smear of Serology Positive Malaria Patients
Abstract: Malaria constitutes one of the maximum percentages of mortal diseases on earth. It is normally definite by abnormalities in many haematological indices with anaemia and thrombocytopenia being almost regular. Malaria is one of the leading causes of morbidity and mortality worldwide. It is estimated that there are about 300–500 million new cases every year, with 1.5–2.7 million deaths worldwide. The study was conducted in population of Anand city, and district …
Published in Research and Reviews: A Journal of Medicine · Vol. 9, Issue 2, 2019 · pp. 15–17 Read article
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Prevalence of Malaria and the Associated Risk Factors among Pregnant Women Attending Antenatal Care in Health Institutions of Damot Woyide District, Wolaita Zone, South Nation Nationalities People Region, Ethiopia, (A Cross-sectional Study)
Abstract: Malaria during pregnancy is a major public health problem in Sub-Saharan African countries such as Ethiopia. The infection is a cause of morbidly and mortality in pregnant women and their fetuses eventually the newborns and infants. Hence, this study was conducted to determine the prevalence and risk factors of malaria among pregnant women that attend ANC clinic in health institutions found in Damote Woyide district, Southern Ethiopia. A health institution …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 8, Issue 3, 2018 · pp. 7–15 Read article