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4 articles for “Levodopa”
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Comparative Efficacy and Safety of Safinamide and Rasagiline in the Treatment of Parkinson’s Disease: A Meta-Analysis and Systematic Review
Abstract: Background: Recent studies have suggested Rasagiline and Safinamide monotherapy as potential management options for Parkinson’s disease. Parkinson’s disease, a neurological disorder characterized by tremors and movement difficulties, necessitates treatments aimed at managing clinical symptoms. Levodopa remains the primary effective treatment for Parkinson’s disease symptoms; however, its long-term use often leads to motor complications in many patients. Additional therapeutic drugs, such as dopamine agonists and monoamine oxidase B inhibitors, including Safinamide …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 3, 2024 · pp. 74–91 Read article
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Pharmacological Management of Parkinson’s Disease: Current Therapies and Emerging Treatments
Abstract: Objective: Parkinson's disease, behind Alzheimer's, is the second most common neurodegenerative ailment and a major cause of neurological morbidity worldwide. Clinical diagnosis is made, and current management is limited to symptomatic treatments, with levodopa remaining the cornerstone of pharmaceutical therapy. In certain patient groups, deep brain stimulation of specific basal ganglia targets can provide significant clinical relief. There are currently no proven disease-modifying medicines in clinical use that can halt …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 1, Issue 1, 2023 · pp. 27–39 Read article
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A General Review of Mucuna Pruriens W.S.R to its effect on Parkinson’s Disease.
Abstract: Mucuna Pruriens is a very famous drug prescribed in classical ayurvedic science in various disorder of Nervous System including Kampavata .In Clinical Practice ,Physician used Levadopa as a Dopamine replacement agent in controlling bradykinetic symptoms apparent in Parkinson disease so used successfully in treatment of Parkinson disease.Kapikacchu(Mucuna Pruriens) is having Balya, Brimhanaha, Vrishya, and Vatahara properties and is a natural source of L-dopa. So, keeping in views of the degenerative …
Published in Research & Reviews : Journal of Herbal Science · Vol. 13, Issue 1, 2024 · pp. 1–6 Read article
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Exploring the Complexities of Parkinson’s Disease
Abstract: Parkinson’s disease (PD) is a neurological disorder, primarily affecting older adults, marked by both motor and non-motor symptoms. This review explores PD as a multisystem disorder that influences the central, enteric, and autonomic nervous systems, along with the immune system and gastrointestinal tract. Key pathogenic features include the degeneration of dopamine-producing neurons in the substantia nigra and the formation of Lewy bodies containing misfolded α-synuclein proteins. The bradykinesia, tremors, stiffness, …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 14, Issue 3, 2024 · pp. 1–8 Read article