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8 articles for “Factor Xa”
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Rivaroxaban: A Comprehensive Review of an Anticoagulant Revolution
Abstract: Rivaroxaban, a prominent direct oral anticoagulant (DOAC), has garnered attention for its pivotal role in preventing and treating thromboembolic diseases. Its introduction into clinical practice has marked a significant advancement in anticoagulant therapy. The mechanism of action of rivaroxaban involves selective inhibition of factor Xa, a crucial component in the coagulation cascade. This targeted approach distinguishes it from traditional anticoagulant and contributes to its efficacy. The significance of rivaroxaban lies …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 10, Issue 3, 2023 · pp. 17–23 Read article
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The Specificity of Purine Derivatives towards Xanthine Oxidase Enzyme and the Factors Affecting the Enzyme Catalyzed Reaction
Abstract: Xanthine oxidase (XO) is a molybdenum-containing enzyme catalyzing the hydroxylation of a sp2-hybridized carbon in a broad range of aromatic heterocycles and aldehydes. Further, it is a key enzyme in the last two steps of purine metabolism. Thus, the need for an understanding and developing unified reaction mechanism to minimize the amount of accumulated uric acid inside human body has led us to the present detailed study of the reaction …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 6, Issue 2, 2016 · pp. 28–44 Read article
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Advanced Lithium-Ion Battery Prognostics: A Comprehensive Review of Machine Learning Approaches for Remaining Useful Life Prediction
Abstract: The lithium-ion battery (LIB), as one of the main sources for portable power systems, has been increasingly popular owing to its widespread applications in electric vehicles, consumer electronics, aerospace and renewable energy. Despite their advantages in high energy density and long cycle life, LIBs suffer from degradation over time of aging and cycling, resulting in loss of performance, safety issues, and economic bottlenecks. Predicting their Remaining Useful Life (RUL) is …
Published in International Journal of Mechanical Dynamics and Systems Analysis · Vol. 3, Issue 2, 2025 · pp. 12–27 Read article
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Analysis of Efficiency Loss in AlGaAs/GaAs Hetero-junction Solar Cell
Abstract: Energy conversion efficiency is a major issue for photovoltaic cells. One of the main challenges of modern day research is to improve the efficiency level of photovoltaic devices by introducing new materials and advanced concepts. The target is to reach a high efficiency level within affordable cost, which will lead to a mass generation of electricity using photovoltaic devices. III-V hetero-junction solar cell has been introduced and characterized here, which …
Published in Journal of Energy, Environment & Carbon Credits · Vol. 6, Issue 3, 2016 · pp. 26–33 Read article
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Formulation And Evaluation Of Captopril Sustained Release Tablet By Qbd Approach.
Abstract: The purpose of present study was to formulation and evaluation of Captopril sustained release tablet by QbD approach using size expanding polymer and cross linker. Captopril is a ACE inhibitor use in treatment of mild to moderate hypertension. Captopril having biological half-life of 2 hrs. The drugs gets degrade as its goes to higher pH, so we selected size expanding GRDDS. In formulation development study by using QbD, we found …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 10, Issue 1, 2023 · pp. 64–73 Read article
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AI-Based Early Diagnosis & Prevention of Diabetes
Abstract: The worldwide burden of Diabetes Mellitus, especially Type 2 diabetes (T2D) has escalated to a critical level. Early detection of diabetes is essential to reduce long‑term complications and healthcare costs. This study explores the use of artificial intelligence (AI) techniques to improve the early diagnosis and prevention of diabetes. We developed an AI model using the Random Forest algorithm, the model predicts diabetes risk based on clinical and lifestyle variables …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 13, Issue 2, 2026 Read article
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Foods of the False Upside-Down Catfish (Synodontis nigrita) from Otamiri River, Rivers State, Nigeria
Abstract: The false upside-down catfish (Synodontis nigrita) from Otamiri River was studied for its food choices in its natural environment by examining its stomach content. Samples of the species were studied using the frequency of occurrence, and number methods. The most important food item (Food Ranking) was determined by index of food significance (IFS). The IFS was estimated as a function of percentage number of food items in the stomach to …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 14, Issue 1, 2025 · pp. 1–5 Read article
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Conventional and Molecular Breeding for Bacterial Leaf Blight and Blast Resistance in Rice
Abstract: AbstractBacterial leaf blight (BLB) and blast are the major limiting factors for rice production in the world. Host resistance mechanism by exploiting the resistance genes (R gene) is one of the most effective ways to achieve the genetic potential of the rice cultivars. Conventional breeding in the past has developed several resistant varieties having major genes for resistance to blast and BLB. Marker-assisted backcross breeding (MABB) provides a long way …
Published in Research & Reviews : Journal of Ecology · Vol. 3, Issue 3, 2014 · pp. 1–3 Read article