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11 articles for “Diabetic kidney disease”
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Clinical metabolomics: Useful insights, perspectives, and challenges.
Abstract: Metabolomics provides a comprehensive snapshot of smallmolecule intermediates and end products of cellular processes and thereby links genotype, environment, and phenotype in human disease . Over the last decade, advances in liquid chromatography–mass spectrometry (LC–MS) and nuclear magnetic resonance (NMR) spectroscopy have enabled high-throughput profiling of thousands of metabolites from microliter volumes of clinical samples . Clinical metabolomics is now emerging as a tool for disease diagnosis, risk prediction, therapeutic …
Published in Emerging Trends in Metabolites · Vol. 3, Issue 1, 2026 · pp. 29–37 Read article
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Assessment of Finerenone Safety and Efficacy in Individuals with Type 2 Diabetes and Chronic Kidney Disease
Abstract: Background: In this work, we provide strong evidence for the safety and efficacy of finerenone in people with type 2 diabetes and chronic kidney disease. Our goal is to improve patients' quality of life and general well-being through our research. Aim: Finerenone exhibited a significant decrease in the likelihood of renal and cardiovascular (CV) events in individuals with both type 2 diabetes and chronic kidney disease. This exploratory subgroup analysis …
Published in International Journal of Antibiotics · Vol. 1, Issue 2, 2024 · pp. 06–09 Read article
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A Study on the Incidence and Prevalence of Cardiovascular Morbidity and Mortality in Patients Undergoing Maintenance Hemodialysis
Abstract: Cardiovascular Disease (CVD) is a major complication for patients with end-stage renal disease (ESRD) on Hemodialysis (HD), with the mortality rate from CVD being nearly 20 times higher than in the general population. As Chronic Kidney Disease (CKD) advances, patients accumulate both traditional and kidney-specific cardiovascular risk factors, such as hypertension, diabetes, fluid overload, electrolyte imbalances, and uremic toxins. These factors contribute significantly to the increased cardiovascular morbidity and mortality …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 14, Issue 3, 2024 · pp. 56–66 Read article
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A summary continuation analysis evaluating the prevalence and predictors of diabetic retinopathy in newly diagnosed type 2 diabetic patients.
Abstract: Context: Diabetic retinopathy (DR), the leading cause of acquired blindness in adults, affects approximately 93 million people globally. It is a serious complication of type 2 diabetes, resulting from prolonged damage to the blood vessels in the retina. Although largely preventable and treatable, DR continues to be the main cause of vision loss among working-age adults and significantly impacts quality of life. While most studies on DR in Nepal have …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 14, Issue 2, 2024 · pp. 21–30 Read article
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A Review Article on Nutraceuticals – An Impact on Conventional Health Care
Abstract: Nutraceuticals, combining nutrition and pharmaceuticals, have transformed healthcare. This review explores their classification, scope, benefits, and challenges. Nutraceuticals, including dietary supplements, functional foods, herbal products, and fortified foods, promote health and prevent diseases. The global market, valued at $117 billion, is expanding rapidly, fueled by the growing focus on health. Key benefits are boosted health benefits, fewer side effects, natural options improved nutrition. Classification is traditional (conventional) nutraceuticals (e.g., lycopene, …
Published in International Journal of Nutritions · Vol. 2, Issue 1, 2025 · pp. 9–23 Read article
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Chronic Kidney Disease: A Comprehensive Review
Abstract: Chronic Kidney Disease (CKD) is a progressive condition characterized by a long-term decline in kidney function, leading to a gradual deterioration of the kidneys' ability to filter waste and maintain fluid balance. It is diagnosed when the Glomerular Filtration Rate (GFR) falls below 60 ml/min/1.73 m² or when there is evidence of kidney damage (such as proteinuria) lasting for 3 months or more. The most common causes of CKD are …
Published in International Journal of Emergency and Trauma Nursing and Practices · Vol. 3, Issue 1, 2025 · pp. 37–42 Read article
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SGLT2 Inhibitors in Heart Failure and Chronic Kidney Disease: Expanding Therapeutic Horizons beyond Glycemic Control
Abstract: Heart failure (HF) and chronic kidney disease (CKD) are closely related clinical diseases that significantly increase morbidity and death worldwide. The co-occurrence of both conditions is frequently referred to as the "cardio-renal syndrome," in which the failure of one organ hastens the decline of the other. The original purpose of sodium–glucose cotransporter-2 (SGLT2) inhibitors was to treat type 2 diabetic mellitus (T2DM) by reducing blood sugar levels. Nevertheless, new data …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 2, 2026 Read article
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In silico analysis of Abrus precatorius L. as a potential agonist of PPARγ : A novel approach to the treatment of diabetes
Abstract: Diabetes mellitus is a chronic disorder that is characterized by a lack of insulin secretion by the pancreas or a defect in insulin action, or both. If diabetes is not controlled, over time it can cause damage to blood vessels and nerves, leading to life-threatening complications such as, kidney damage, heart disease and vision impairment. It can also weaken the immune system, making patients more prone to infection. Although treatments …
Published in International Journal of Molecular Biotechnological Research · Vol. 3, Issue 2, 2025 Read article
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Non-Invasive Glucose Monitoring Device Using Max30102 Sensor
Abstract: Diabetes mellitus is a chronic metabolic disorder affecting millions globally, requiring continuous blood glucose monitoring to prevent complications such as cardiovascular disease, kidney failure, neuropathy, and retinopathy. Conventional invasive finger- prick techniques result in pain, skin irritation, and an increased risk of infection, which lowers patient compliance, particularly in young patients and the elderly. This paper presents a non-invasive glucose monitoring prototype using the MAX30102 optical biosensor interfaced with the …
Published in Journal of Instrumentation Technology & Innovations · Vol. 16, Issue 1, 2026 · pp. 36–44 Read article
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Managing Chronic Diseases: Diabetes Mellitus
Abstract: Diabetes mellitus is one of the most prevalent chronic non-communicable diseases worldwide and represents a major public health challenge due to its long-term complications, increasing prevalence, and economic burden on individuals and healthcare systems. It is distinguished by chronic hyperglycemia brought on by deficiencies in either insulin action or secretion, or both. Diabetes causes increasing harm to several organ systems, including the kidneys, eyes, neurological system, and cardiovascular system, if …
Published in International Journal of Antibiotics · Vol. 3, Issue 2, 2026 Read article
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Determining the Root Causes of Complications in Hemodialysis Maintenance Therapy
Abstract: As with peritoneal dialysis and kidney transplantation, hemodialysis has been considered one of the most effective therapies for the replacement of kidney function. While this helps to save patients with the disease by decreasing morbidity /mortality/ rates, this medication has some side effects. These may manifest during the dialysis process alongside the ongoing treatment. Avoiding these barriers becomes crucial for improving the patients’ prognosis in this context.We are going to …
Published in Emerging Trends in Metabolites · Vol. 1, Issue 1, 2024 · pp. 27–47 Read article