Search

1 article for “Captopril”

• Published Subscription 4 Aug 2023

  Formulation And Evaluation Of Captopril Sustained Release Tablet By Qbd Approach.

  By JAIMIN B. PATEL, DR. PARESH PRAJAPATI, DR. RAKSHIT SONALPAL, MR. BHAVIN BHIMANI, DR. UPENDRA PATEL

  Abstract: The purpose of present study was to formulation and evaluation of Captopril sustained release tablet by QbD approach using size expanding polymer and cross linker. Captopril is a ACE inhibitor use in treatment of mild to moderate hypertension. Captopril having biological half-life of 2 hrs. The drugs gets degrade as its goes to higher pH, so we selected size expanding GRDDS. In formulation development study by using QbD, we found …

  Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 10, Issue 1, 2023 · pp. 64–73 Read article →