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2 articles for “Bilayered patch”

• Published Subscription 16 Jun 2021

  Preparation and Evaluation of Mucoadhesive Bilayered Buccal Patch using HPMC and Gelatin

  By Anjali Patel, Basudha Singh Gautam, Utpal Jana

  Abstract: The buccal drug delivery system has gained more popularity than other drug delivery systems owing to its ease and safe administration. The high permeability of the buccal mucosa allows the drug to reach the systemic circulation and gives rapid onset of action. The buccal route also helps to avoid drug degradation from first-pass hepatic metabolism and improves drug bioavailability. The present study is designed to develop and evaluate the mucoadhesive …

  Published in Trends in Drug Delivery · Vol. 8, Issue 1, 2023 · pp. 5–13 Read article →

• Published Subscription Review Article Special issue 30 Aug 2025

  Polymer Chemistry in Sustained-Release Herbal Composites: Designing a Stable Euphorbia tithymaloides Topical System with Phospholipid and Polymer Matrices

  By Amar Mohite, Rohan Sharadanand Phatak, Vyankatesh R. Dharanguttikar, Swapnali Thorat, Atul R. Chopade, Jayant Rajaram Pawar

  Abstract: Polymer chemistry enables the stabilization and sustained release of herbal actives, critical for topical therapeutic applications. This study explores a novel process for preparing a stable, sustained-release topical composition of Euphorbia tithymaloides, leveraging polymer-based systems. Ethanolic extract (50 mg) of the plant, rich in unstable sugar moieties (e.g., D-ribose) and sterols (e.g., stigmasterol), is encapsulated within a phospholipid matrix of phosphatidylcholine (50–100 mg) and cholesterol (50–100 mg). This lipid-polymer complex, …

  Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 165–171 Read article →