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5 articles for “Beta-lactamase”
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Extended Spectrum Beta-Lactamase Production By Acinetobacter baumannii Isolated From Hospital Environment
Abstract: Extended spectrum β-lactamases production was determined by Double Disc synergy test for twenty one bacterial isolates of Acinetobacter bumannii isolated from the hospital environment. This study investigates the prevalence, genetic mechanisms, and clinical implications of ESBL production by A. baumannii. We employed molecular techniques to identify and characterize ESBL genes in clinical isolates, alongside evaluating their susceptibility profiles against a range of antibiotics. These resistant strains were notably associated with …
Published in International Journal of Antibiotics · Vol. 2, Issue 1, 2025 · pp. 71–78 Read article
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Review: Virulence factors, resistance genes and pathogenicity of Moraxella catarrhalis
Abstract: An estimated 2-4 million cases of chronic obstructive pulmonary disease(COPD) in adults are exacerbated by Moraxella catarrhalis annually in the US, making it a pathogen of increasing significance for respiratory tract infections. It often colonizes the nasopharynx without causing any symptoms and an opportunistic bacterial infection of the respiratory mucosa that is exclusive to humans. In our study, we reviewed references about the important virulence factors that M. catarrhalis possess …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 1, 2025 · pp. 33–40 Read article
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A Pilot Study on β-lactamase Producing Escherichia coli from Bovine Milk, West Bengal
Abstract: Drug resistant bacteria have become a significant global healthcare issue that requires close attention. With regards to antibiotic resistance, E.coli and its Enterobacteriaceae family are highly notorious for their ability to swiftly spread antibiotic resistance genes, thereby posing a major concern. In order to effectively address the spread of multi drug resistant bacteria, ongoing monitoring of the microflora in milk for the presence of drug resistant genes is essential. This …
Published in International Journal of Toxins and Toxics · Vol. 1, Issue 1, 2024 · pp. 01–05 Read article
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Pathogens in Nosocomial Infections: Epidemiology, Resistance, and Control Measures
Abstract: Nosocomial infections, also known as healthcare-associated infections (HAIs), are a serious global health issue, leading to higher patient morbidity, prolonged hospital stays, and increased medical costs. Various pathogens—such as bacteria, viruses, fungi, and parasites—are responsible for these infections, especially in healthcare environments where they easily spread. They can be transmitted through direct contact with infected patients, contaminated medical equipment, or even airborne particles.Patients with weakened immune systems, those requiring prolonged …
Published in International Journal of Pathogens · Vol. 2, Issue 1, 2025 · pp. 12–16 Read article
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A study on Antibiotic Resistance: An Analysis of Molecular Mechanisms and Therapeutic Implications
Abstract: Antibiotic resistance (AR) represents one of the most critical existential threats to global public health, rapidly eroding the efficacy of established antimicrobial therapies and portending a return to the pre-antibiotic era. This analysis explores the intricate molecular landscape defining this crisis, focusing specifically on the primary mechanisms of action (MoA) utilized by major antibiotic classes—including cell wall inhibitors, protein synthesis inhibitors, and nucleic acid synthesis inhibitors—and the corresponding, diverse mechanisms …
Published in International Journal of Antibiotics · Vol. 3, Issue 1, 2026 · pp. 9–21 Read article