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3 articles for “Amyloid cascade hypothesis”
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The Pathophysiology, Diagnosis and Some Management Approaches of Alzheimer’s Disease: An Overview
Abstract: Alzheimer’s disease is the greatest mutual cause of dementia globally, with the occurrence ongoing to grow in part because of the aging world populace. This neurodegenerative disease process is categorized characteristically by 2 mark pathologies: β-amyloid plaque deposition and neurofibrillary masses of hyperphosphorylated tau. Diagnosis is grounded on biomarkers restrained in vivo even beforehand the onset of clinical dementia symptoms. No solitary biomarker can by itself properly diagnose AD. A …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 8, Issue 2, 2023 · pp. 1–17 Read article
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“Alzheimer†An Ambiguous Ailment; A Comprehensive Review
Abstract: Alzheimer Disease (AD) is a gradually progressive dementia affecting cognition, behavior, and functional status. It was discovered a century back (1907) characterized by defects in language use, visual-spatial perception, ability to learn, solve problems, perform mathematical calculations, thinking abstractly, and making appropriate judgments, affecting more than 4.5 million people in United States. 100,000 people die of AD every year, nevertheless hundred years have been passed after the discovery of AD …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 5, Issue 3, 2014 · pp. 8–16 Read article
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An Overview of Artificially Generated Neural Networks Inside the Brain’s Structure in an Alzheimer’s Disease Patient
Abstract: Alzheimer’s disease produces significant neuronal loss, while the precise mechanisms and timing are yet unknown. Other types of cell death, such necroptosis, parthanatosis, ferroptosis, and cuproptosis, need further investigation. Based on brain images of people with mild cognitive impairment, this study assesses artificial neural networks (ANNs) used to diagnose and predict Alzheimer’s disease (AD). This research was conducted considering growing recognition among researchers and medical professionals regarding the importance of …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 15, Issue 2, 2025 Read article