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445 articles for “future directions”
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The Role of Simulation and Digital Twins in Enhancing Mechanical Production Efficiency: A Systematic Review
Abstract: In the evolving landscape of smart manufacturing, simulation technologies and digital twin (DT) systems have emerged as pivotal tools for enhancing the efficiency, agility, and sustainability of mechanical production processes. This systematic review investigates how the integration of simulations and DTs contributes to performance improvements across various stages of mechanical manufacturing—ranging from design and process optimization to predictive maintenance and real-time monitoring. While simulations provide the ability to model, test, …
Published in Journal of Production Research & Management · Vol. 15, Issue 2, 2025 · pp. 31–36 Read article
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Harnessing Polymer Chemistry for Pharmaceutical Technology
Abstract: Polymer chemistry has emerged as a cornerstone of modern pharmaceutical technology, offering unprecedented control over drug formulation, delivery, and therapeutic performance. This review highlights the pivotal role of polymers—both synthetic and natural—in revolutionizing drug delivery systems across various routes, including oral, parenteral, transdermal, ocular, nasal, and pulmonary administration. Special emphasis is placed on the structural and functional versatility of polymers, which allows for tailored drug release profiles, enhanced bioavailability, and …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 1–6 Read article
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Polymer Chemistry in Nutraceutical Composites: Exploring Natural Polymers and Binding Systems in a Bamboo-Enhanced Formulation
Abstract: Polymer chemistry underpins the development of advanced nutraceutical composites, blending natural polymers with functional ingredients for health benefits. This study examines a novel nutraceutical formulation comprising ragi (16.39 g/100g), wheat (12.29 g/100g), soybean (12.29 g/100g), buffalo milk (16.39 g/100g), buffalo butter (4.13 g/100g), bamboo extract (0.90 g/100g), and auxiliary components (37.61 g/100g, including fats, sugars, and proteins). Natural polymers—proteins from soybean and milk, polysaccharides from ragi and wheat—form a macromolecular …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 878–884 Read article
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Advancing Cancer Vaccine Development through CRISPR/Cas9 Technologies and Future Opportunities
Abstract: The advent of CRISPR/Cas9 genome editing has revolutionized the cancer immunotherapy market, offering unprecedented precision and versatility in the development of next-generation cancer vaccines. This review examines how CRISPR technologies are being integrated into various stages of cancer vaccine development including neoantigen discovery, dendritic cell engineering, cancer cell reprogramming, and tumor microenvironment modulation. In the area of neoantigen discovery, CRISPR enables rapid identification and validation of tumor-specific mutations, thereby supporting …
Published in International Journal of Vaccines · Vol. 2, Issue 2, 2025 Read article
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Review article on Quality Control in Clinical Trials
Abstract: Quality control (QC) is a critical component in the conduct of clinical trials, ensuring the accuracy, reliability, and credibility of data collected throughout the study. It encompasses a systematic set of procedures designed to monitor trial conduct and data integrity, thus safeguarding the rights, safety, and well-being of participants. This review explores the principles, implementation, and evolving practices of quality control in clinical trials, highlighting its importance across all phases …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 3, 2025 · pp. 01–07 Read article
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Accelerating Unsupervised Feature Learning: Parallelized Training of Denoising Autoencoders
Abstract: Unsupervised representation learning has become a cornerstone of contemporary machine learning, enabling algorithms to extract informative features from un-labelled, high-dimensional data. This work investigates the efficacy of stacked denoising autoencoders (SDAEs) trained via parallelized stochastic gradient descent (SGD) as a scalable approach to feature extraction. By strategically leveraging multi-threaded computation, our study systematically examines the trade-offs between increased parallelism, training efficiency, and the preservation of model accuracy. Experiments on the …
Published in Journal of Image Processing & Pattern Recognition Progress · Vol. 12, Issue 3, 2025 · pp. 56–64 Read article
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Codal Validation and Optimization of Gantry Girders Under Variable Wheelbase and Impact Loads: A Review of Analytical, Numerical, and Codal Approaches
Abstract: Gantry girders serve as critical structural elements in industrial facilities such as steel plants, workshops, and heavy manufacturing units, where electric overhead traveling (EOT) cranes operate. The design of these girders is governed by stringent codal provisions to ensure safety under bending, shear, and deflection. However, discrepancies between codal predictions, analytical formulations, and finite element analysis (FEA) results, particularly under variable wheelbase and dynamic impact loads, have been widely reported. …
Published in Journal of Offshore Structure and Technology · Vol. 12, Issue 3, 2025 · pp. 23–29 Read article
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Exploration of Advanced Phase Change Materials for Thermal Energy Storage in Renewable Energy Systems: An Overview
Abstract: Phase Change Materials (PCMs) are increasingly vital for improving thermal energy storage (TES) systems. Their ability to absorb and release heat efficiently makes them ideal for renewable energy applications, enhancing energy efficiency, reducing waste, and supporting sustainable energy solutions across various sectors like solar power and building temperature regulation. Their ability to store and release latent heat during phase transitions makes them ideal for addressing the intermittency of renewable energy …
Published in Journal of Thermal Engineering and Applications · Vol. 12, Issue 3, 2025 · pp. 10–14 Read article
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CB₁ Reverse Agonists: A Cheminformatic and Patent Landscape Study
Abstract: The endocannabinoid system plays a crucial role in numerous physiological functions, making cannabinoid receptor 1 (CB1) an attractive target for therapeutic development. This review provides a systematic analysis of patent filings from 2019 to 2023 that focus on small-molecule CB1 reverse agonists. It begins with an overview of the endocannabinoid system, highlighting CB1’s involvement in energy balance, pain regulation, and neuroinflammatory processes The main section of the review examines fifteen …
Published in International Journal of Cheminformatics · Vol. 3, Issue 2, 2025 · pp. 33–36 Read article
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Metals and Minerals in Pharmacy: Current Trends, Biomedical Applications, and Future Innovations
Abstract: Metals and minerals have played important roles in medicine for centuries, ranging from the use of simple mineral powders in traditional therapies to the development of modern metal-based drugs and nanomaterials. In recent years, advancements in material science, nanotechnology and pharmaceutical engineering have expanded the biomedical relevance of inorganic materials far beyond their conventional use as excipients. This review highlights the growing integration of metallic and mineral systems into pharmaceutical …
Published in International Journal of Minerals · Vol. 2, Issue 2, 2025 · pp. 12–24 Read article
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Advances in Laser Hardening: A Review on Techniques, Trends and it’s Applications
Abstract: This review paper examines laser hardening, an advanced surface treatment method, and its impact on automotive components. By analyzing findings from numerous studies, the paper categorizes various laser hardening techniques and evaluates the effect of parameters like speed of scanning , power of laser and beam diameter on material performance. Special attention is given to the microstructural changes and wear resistance enhancements achieved through laser hardening, highlighting its precision and …
Published in International Journal of Solid State Innovations & Research · Vol. 3, Issue 2, 2025 · pp. 1–10 Read article
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Innovations and Practices in Ornamental Horticulture: Integrating Landscape and Garden Design for Sustainable Aesthetics
Abstract: Ornamental horticulture is a specialized branch of horticultural science focusing on the cultivation, management, and utilization of plants for decorative and environmental purposes. With growing urbanization and lifestyle shifts, the importance of aesthetically pleasing and ecologically sustainable green spaces has significantly increased. Landscape design and garden design, both integral components of ornamental horticulture, contribute not only to the beautification of spaces but also to environmental conservation, mental well-being, and biodiversity …
Published in International Journal of Trends in Horticulture · Vol. 2, Issue 2, 2025 · pp. 13–19 Read article
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Recent Developments in Hybrid and Nanostructured Basalt Fiber Composites: A Review of Mechanical and Processing Innovations
Abstract: This review delivers a critical analysis of recent advancements in basalt fiber-reinforced hybrid composites (BFRHCs), emphasizing their transformative potential for advanced structural and high-performance applications. Basalt fibers, derived from volcanic rock, exhibit superior tensile strength, excellent thermal stability, and chemical resistance, offering a sustainable and cost-effective alternative to conventional glass and carbon fibers. Hybridization of basalt fibers with synthetic (e.g., carbon, glass) and natural fibers (e.g., flax, hemp) results in …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 885–894 Read article
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Entropy, Symmetry, and Data Fusion: Emerging Methods in Multi-Objective Decision- Making and Smart Systems
Abstract: In the era of intelligent technologies and data-driven systems, multi-objective decision-making (MODM) has become an essential aspect of managing complex environments such as smart cities, autonomous systems, and cyber-physical networks. As decision-making scenarios become increasingly dynamic and uncertain, there is a growing need for advanced methodologies that can handle diverse objectives, conflicting constraints, and incomplete information. This review highlights the emerging role of entropy, symmetry, and data fusion as foundational …
Published in Emerging Trends in Symmetry · Vol. 1, Issue 2, 2025 · pp. 44–49 Read article
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Automation and Robotics for Quality Control in Manufacturing: A Review of Technologies and Applications
Abstract: Automation and robotics technologies have rapidly evolved, transforming modern manufacturing processes by improving productivity, quality, and operational efficiency. This review examines key advancements such as cloud robotics, machine vision, Industry 4.0 robotics, Building Information Modeling (BIM) combined with Computer Numerical Control (CNC), joystick-controlled automation, and intelligent manufacturing systems. These technologies utilize artificial intelligence (AI), machine learning (ML), digital twins, collaborative robots, programmable logic controllers (PLCs), and cyber-physical systems (CPS) to …
Published in Journal of Mechatronics and Automation · Vol. 12, Issue 3, 2025 · pp. 36–48 Read article
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Cosmeceuticals: Integrating Therapeutic Functionality into Cosmetic Science
Abstract: Cosmeceuticals are a quickly growing group of skincare products that are in between cosmetics and drugs. These products have biologically active components that are said to provide medical or drug-like advantages for a number of skin problems, including ageing, hyperpigmentation, acne, and damage from the sun. Cosmetics are not medications, but cosmeceuticals are made to affect skin function at the cellular level. This article talks about what cosmeceuticals are, how …
Published in Recent Trends in Cosmetics · Vol. 2, Issue 2, 2025 · pp. 19–35 Read article
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Temporal Shifts in Forage Quality: Stage of Maturity, Biomass Yield, Performance Matrix, and Ecosystem Responses
Abstract: Forage quality is a key determinant of livestock productivity and environmental sustainability, with its dynamics closely linked to the stage of maturity, biomass yield, and broader ecosystem interactions. This study explores the temporal shifts in forage quality throughout its growth cycle, emphasizing the effects of maturity on nutrient composition, digestibility, and overall biomass yield. The relationship between these factors and their impact on animal performance, including milk yield, growth, and …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 4, Issue 1, 2026 Read article
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Biodegradable and Natural Fiber-Reinforced Polymer Composites for Sustainable Biomedical Applications
Abstract: Liposomal drug delivery has evolved into a viable approach in modern pharmacology thanks to its enhanced bioavailability, reduced systemic toxicity, and targeted drug release. Conventional liposomes have limited stability, medicine leakage, and short circulation times among other problems. Overcoming these limits, the inclusion of nano-polymers into liposomal formulations has transformed medication delivery. Thorough research has been done on the potential of nano-polymers including chitosan, hyaluronic acid, polyethylene glycol (PEG), and …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 420–432 Read article
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Advancements in Thin Film Coatings for High-Efficiency Electronics and Communication Devices
Abstract: Thin film coatings have become integral to the development of high-efficiency electronics and communication devices, offering enhanced performance, miniaturization, and multifunctionality. This review delves into recent advancements in thin film technologies, focusing on their applications in semiconductors, optoelectronics, and communication systems. We explore various deposition techniques, including atomic layer deposition (ALD), chemical vapor deposition (CVD), and solution-based methods like spin coating, highlighting their impact on device efficiency and scalability. The …
Published in Journal of Thin Films, Coating Science Technology & Application · Vol. 12, Issue 2, 2025 · pp. 19–24 Read article
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A Review of Torque Ripple Reduction Techniques in Switched Reluctance Motors
Abstract: Switched Reluctance Motors (SRMs) have emerged as a promising alternative to conventional motor technologies due to their rugged structure, low manufacturing cost, high-temperature capability, and suitability for harsh environments. Despite these advantages, the widespread adoption of SRMs in applications such as electric vehicles, household appliances, industrial drives, and aerospace systems is significantly restricted by the issue of torque ripple. Torque ripple manifests as periodic fluctuations in the developed electromagnetic torque, …
Published in International Journal of Electrical Machine Analysis and Design · Vol. 3, Issue 2, 2025 · pp. 45–50 Read article