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206 articles for “radical”
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Comparative Effectiveness of Surgical and Nonsurgical Management for Patients with Single Level Lumbar Disc Herniation in terms of Symptom Severity and Quality of Life
Abstract: Background: Sciatica is one of the most severe forms of low back pain, with a lifetime prevalence of approximately 30 percent. Aim: To assess the short-term and long-term efficacy of surgical and conservative care in the incidence of sciatic symptoms and quality of life in standard clinical settings among patients with lumbar disc herniation. Material and Method: It was a retrospective study conducted at the Medical Trust Hospital, Kochi, India. …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 10, Issue 1, 2020 · pp. 25–29 Read article
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Triple Negative Breast Cancer—Pattern of Recurrence and Survival: A Single Institute Experience
Abstract: Triple negative breast cancer (TNBC) is a distinct biological entity and recent data shows it as a heterogeneous group with at least 6 subtypes with differences in clinical outcome.This study intends to analyze the prevalence, recurrence pattern and outcome of triple negative breast cancer in our patient cohort.We reviewed the outcomes of 244 consecutive triple negative non-metastatic breast cancer patients who were treated with a radical intent from Jan 2004 …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 6, Issue 3, 2017 · pp. 5–8 Read article
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Nitric Oxide Synthase (NOS) in Breast Carcinoma
Abstract: Breast cancer is the most alarming problem of the current time. Nitric oxide, a free radical gas is synthesized by isoenzymes called nitric oxide synthase. Nitric oxide synthase consists of three isoforms; Nitric oxide produced is cytotoxic which is known to inhibit the DNA synthesis causing its damage. Keeping this in mind, nitric oxide synthase was determined in breast cancer and normal breast tissue. For this tissue from 60 breast …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 7, Issue 1, 2018 · pp. 23–28 Read article
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Efficacy of Tele Rehabilitation in A Stroke Survivor with Aphasia: An Extensive case study
Abstract: Tele-rehabilitation refers to a mode of service delivery where therapy is imparted through tele-mode and tele-rehabilitation is extensively used in the treatment of communication disorders. Many efficacy studies have been reported earlier especially in clients with aphasia; however, most of these studies are western studies and the results cannot be generalised to Indian context, this fact necessitated the present study. The present attempt is a case study; the client was …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 8, Issue 1, 2019 · pp. 10–13 Read article
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Correlation of Ki-67 Score with Nottingham Histological Grading in Carcinoma Breast: A Single Institution Experience
Abstract: Though it is reasonably well established that Ki-67 positivity is an independent predictor of ultimate prognosis and course of carcinoma breast and its recurrence, many lacunae exist. Ki -67 score correlation with histological grading will establish importance of nuclear antigen Ki-67 as prognostic factor in Indian population. This study was aimed to assess histological grading of breast carcinoma by Nottingham Grading System (Modified Scarff- Bloom- Richardson system) and to correlate …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 6, Issue 1, 2017 · pp. 1–5 Read article
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Multiple Intestinal and Mesentrical Lymphangiomas in a 16-year-old Male: A Case Report
Abstract: Lymphangiomas are rare benign tumor of lymphatic vasculature. These usually occur in skin and soft tissues ofhead, neck and axillary region. Very rarely these affect gastrointestinal tract. Here, we present a case of lymphangiomatos is in a 16 year old male who was presented with acute abdomen. Exploratory laparo to my done and multi-lobulated mass in the intestinal wall and mesentry found. Segment of ileum, caecum and part of colon …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 5, Issue 3, 2016 · pp. 41–44 Read article
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Serum Advanced Oxidation Protein Products (Aopp) in Oral Squamous Cell Carcinoma (Oscc): Possible Markers of Diagnostic Significance
Abstract: The aim of this study was to measure the concentrations/levels of serum, total proteins and advanced oxidation protein products as the markers of oxidant mediated protein damage in the sera of patients with oral cancers. The study consisted of the sera analysis of serum total protein, albumin and advanced oxidation protein products’ levels in 30 age and sex-matched controls, 60 patients with reported pre-cancerous lesions and/or conditions and 60 patients …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 1, Issue 1, 2012 · pp. 16–29 Read article
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Role of Axillary Reverse Mapping in Reducing the Risk of Lymphedema in Breast Cancer Patients: Current Perspectives
Abstract: Axillary reverse mapping is the technique of mapping and subsequently preserving the arm lymphatic drainage during axillary dissection. In 2007 Hiroo Suami described a constant sentry node draining most of the upper limb in anatomical dissection of cadavers. The presence of this node and its fairly constant location was later confirmed by many authors in clinical studies. With the use of blue dye alone, the detection rates are low than …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 6, Issue 1, 2017 · pp. 6–10 Read article
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Role of Nitric Oxide in Platelets of Breast Carcinoma
Abstract: Breast cancer is a disease of multifactorial origin; it is seen frequently in women of older age, having family history, affluent society, late age of marriage and first childbirth, early menarche, late menopause, and nulliparity. Oxidative stress results when balance between reactive oxygen species (ROS) production and antioxidant defence is lost which result in mutations, sister chromatid exchanges, cytotoxicity, carcinogenesis etc. Clinical, experimental and epidemiological studies suggest that free radicals …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 8, Issue 2, 2019 · pp. 25–29 Read article
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Cystic Duct Adenocarcinoma: A Case Report and Review of Literature
Abstract: Cystic duct adenocarcinoma is a rare tumour arising from biliary epithelium. It may occur anywhere in the biliary tree. Many patients come in advanced stages, however surgical resection is the only chance offered for cure. A 35 year old female presented with obstructive jaundice along with intense itching all over body, at the surgical OPD. On examination gall bladder was palpable. Her USG abdomen and pelvis was suggestive of obstructive …
Published in Research and Reviews : Journal of Surgery · Vol. 4, Issue 1, 2015 · pp. 12–15 Read article
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Epidemiology and Clinical Profile of Liver Abscess from a Tertiary Care Hospital in Northern India
Abstract: Background: Liver abscess is defined as a localized collection of supportive material encapsulated within the liver parenchyma due to inflammatory necrosis secondary to bacterial, amoebic, tubercular, or fungal pathogens. Male gender, advanced age liver cirrhosis, proton pump inhibitors low socioeconomic status, alcoholism, diabetes, immunodeficiency states and poor hygiene are few of the risk factors mentioned in literature that are associated with Liver abscess. In the past decade, the treatment protocol …
Published in Research and Reviews : Journal of Surgery · Vol. 11, Issue 1, 2022 · pp. 1–6 Read article
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Endosulfan-Induced Hepatotoxicity and its Amelioration by Administration of Bamboo (Dendrocalamus Strictus) Seed Extract in Rats
Abstract: Endosulfan is an important hepatotoxic agent that generates free oxygen radicals in liver and the incidence of toxic injury to the liver tissue in relation to its widespread has been reported. Bamboo is rich in phenolic components which possess various bioactivities and bamboo seed extract was found to have antioxidative properties. Hence, the present study has been designed to assess the protective role of bamboo seed extract against endosulfan induced …
Published in Research and Reviews: A Journal of Toxicology · Vol. 4, Issue 1, 2014 · pp. 1–7 Read article
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Gossypetin Inhibits ROS Generation in HeLa and HepG2 Cell Lines
Abstract: Antioxidants are known for their ability to neutralize the reactive oxygen species present within the living system. These antioxidants are mainly secondary metabolites present in plant products and are generally known as nutraceuticals or bioactive compounds. Antioxidant can be categorized into many categories based upon their structure and activities like flavonoids, anthrocyanins and carotenoids. Flavonoids are heterogeneous polyphenolic compounds having beneficiary effect on human body and are also known to …
Published in Research and Reviews: A Journal of Toxicology · Vol. 7, Issue 1, 2017 · pp. 25–31 Read article
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Protective Effect of Epigallocatechin Gallate (EGCG) on Sodium Fluoride (NaF) Induced Changes in Histology of Selected Organs in Rats
Abstract: Histopathology is the microscopical examination of biological tissues to observe the appearance of diseased cells and tissues in very fine detail. The present study, has been designed to evaluate the effects of oral administration of Sodium Fluoride (NaF) 25 mg/kg/bw (orally), NaF with EGCG (40 mg/kg/bw) daily for four weeks on histological alterations, if any on heart, liver, kidney and testes of rats. Rats were weighed about 160–180 g. NaF …
Published in Research and Reviews: A Journal of Toxicology · Vol. 3, Issue 1, 2013 · pp. 20–26 Read article
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Effects of Smoking on Respiratory System
Abstract: Smoking is whispered to exacerbate respiratory diseases by harming respiratory defense mechanisms. Specifically, smoking damages mucociliary function, which impairs clearance of inhaled substances even in smokers who have no respiratory symptoms promotes bacterial adherence to airway epithelial cells. The devastating health impact of cigarette smoking is well known, Cigarette and its components produce structural changes in the respiratory tract include peri-bronchiolar inflammation and fibrosis, augmented mucosal permeability, destruction of the …
Published in Research and Reviews: A Journal of Toxicology · Vol. 3, Issue 3, 2013 · pp. 5–8 Read article
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Gnidia glauca: A Review on Pharmacological Activities
Abstract: For thousands of years, people have used medicinal plants as a source of healing in their communities all around the world. The traditional Indian herbal medicines have their own value in the health care sector. In Indian system of medicine, Ayurveda, one of the plants Gnidia glauca is a flowering plant belonging to family Thymelaeaceae. According to study, G. glauca has antidiabetic, antioxidant, antifungal, antibacterial, anticarcinogenic, locomotor activity, anxiety and …
Published in Research and Reviews: A Journal of Toxicology · Vol. 12, Issue 3, 2022 · pp. 27–32 Read article
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Concept of Hemorrhoid (Bawaseer) and Management in Unani System of Medicine: A Review
Abstract: Hemorrhoids are dilated veins within the anal canal in the sub-epithelial region formed by radicles of the superior and inferior rectal veins. The basic cause of bulging of veins (piles) is increase in intra-abdominal pressure as in the case of obesity, constipation and pregnancy. It is a common ailment among adults. In Unani system of medicine, hemorrhoids are known as bawaseer. Buqrat (Hippocrates) (460–377BC), the renowned Unani physician, stated that …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 5, Issue 2, 2018 · pp. 15–18 Read article
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Development of Antioxidant Based Therapeutics in Unani System of Medicine
Abstract: During the last decades, several studies have examined the potential role of oxidative stress in the development of various diseases like cancer, Parkinson's disease, Alzheimer's disease, atherosclerosis, myocardial infarction, chronic fatigue syndrome etc. Oxidative stress can cause toxic effects through the production of peroxides and free radicals that damage all components of the cell, including proteins, lipids, and DNA. Unani system of medicine has a wealth of antioxidants that can …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 5, Issue 3, 2018 · pp. 1–4 Read article
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Integrated Approach of Unani Medicine in Geriatric Care
Abstract: Aging is a process of physical, psychological and social changes in multidimensional aspects. The percentage of elderly, in the world population is expected to increase rapidly from 9.5% in 1995 to 20.7% in 2050 and 30.5% in 2150. In India, the population of older people has risen from 4.9% in 1901 to 5.5% in 1951, 6.5% in 1991, 7.7% in 2001, and 8.3% in 2011 and will be 12% in …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 2, Issue 1, 2015 · pp. 4–9 Read article
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Comparative Evaluation of the Effect of Adhesive Restorative Techniques on the Reinforcement of Simulated Immature Permanent Teeth: An in Vitro Study
Abstract: The aim of the study was to compare the reinforcement effect of 3 different adhesive restorative techniques on simulated immature maxillary central incisors after apexification. A total of 30 simulated immature permanent maxillary central incisors were randomly assigned into 3 groups (n=10), according to the reinforcing technique used: Group 1: Nanohybrid composite. (Tetric N-Ceram Ivoclar Vivadent), Group 2: Short-fiber reinforced composite (everX posterior GC EUROPE) extended 3mm below CEJ, covered …
Published in Journal of Polymer & Composites · Vol. 10, Issue 3, 2022 · pp. 69–75 Read article