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448 articles for “Implication”
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Effectiveness of Temporins for the Treatment of HPV Infections
Abstract: Objectives: Human papillomavirus (HPV), especially high-risk variants like type-16 have been linked to the formation of malignant tumors. HPV-16 has been implicated in most cases of cervical cancer in women. This study aims to assess the effectiveness of three types of temporin molecules, i.e., antiviral peptides secreted by certain frog species, for the inhibition of the viral L1 protein. Methods: In the present study, various computational tools were used to …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 2, Issue 1, 2024 · pp. 41–53 Read article
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Precision Medicine for Neurofibromatosis Type 1: Progress and Prospects in Drug Discovery
Abstract: Objective: The development of neurofibromas, café-au-lait spots, and other neurological problems are the hallmarks of neurofibromatosis type 1 (NF1), a hereditary disorder. The dearth of efficacious pharmaceutical therapies underscores the need for novel therapeutic approaches, even in the face of clinical variability. Through very accurate prediction of the binding affinity of possible therapeutic drugs with the target protein, the computational technique known as “molecular docking” has become a potent tool …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 2, Issue 1, 2024 · pp. 01–15 Read article
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Use of Earthen Materials in Interior Spaces
Abstract: This research paper investigates the utilization of earthen materials within interior spaces, focusing on their sustainable attributes and aesthetic potential. In the context of contemporary design practices, there is a growing interest in integrating natural materials that offer environmental benefits and promote well-being. Earthen materials, including clay, adobe, terracotta, and rammed earth, present promising opportunities for sustainable interior design solutions. The research begins by examining the historical and cultural significance …
Published in International Journal of Architectural Design and Planning · Vol. 2, Issue 1, 2024 · pp. 40–49 Read article
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String Theory: Simplified Insights into Reality
Abstract: "String Theory: Simplified Insights into Reality" explores the fascinating realm of theoretical physics, delving into the profound principles of string theory and its implications for our understanding of the fundamental nature of the universe. The paper begins with an overview of the historical context, tracing the evolution of string theory from its inception as a theoretical framework to its current status as a leading candidate for a unified theory of …
Published in Research & Reviews : Journal of Space Science & Technology · Vol. 13, Issue 1, 2024 · pp. 1–11 Read article
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Pharmacological Review On Enzalutamide
Abstract: A key therapeutic option in the treatment of prostate cancer, especially metastatic castration-resistant prostate cancer (mCRPC), is Enzalutamide, a second-generation anti androgen drug. Enzalutamide, discovered by Charles Sawyer and Michael Jung at the University of California, Los Angeles, was developed and Food and Drug Administration (FDA)-approved in 2012. Its therapeutic significance was further solidified with subsequent extensions in indications to encompass metastatic castration-sensitive prostate cancer and non-metastatic castration-resistant prostate cancer. …
Published in Trends in Drug Delivery · Vol. 11, Issue 2, 2024 · pp. 7–15 Read article
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Unveiling the Engine of Efficiency: Exploring the Vital Dimensions of Warehousing for Optimal Operational Performance
Abstract: This research endeavours to comprehensively explore the multifaceted dimensions of warehousing that significantly influence operational efficiency within the bustling industrial nexus of the National Capital Region (NCR), encompassing a diverse array of warehouse types in the vicinity of Delhi-NCR. Employing a meticulously crafted structured questionnaire, respondents provided insights through a Likert scale, ranging from 1 = Strongly Disagree to 5 = Strongly Agree. The data collection process, utilizing stratified sampling …
Published in Journal of Production Research & Management · Vol. 14, Issue 1, 2024 · pp. 29–38 Read article
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PCM with Multiple Node Injections
Abstract: Phase-Changing Materials (PCM) are currently being investigated for use as heat storage in solar energy applications. To analyze the temperature profile, morphing tree structures are used to simulate the melting algorithm of Phase Changing Material with increasing branch numbers. The melting behavior is simulated for invading lines of heat, which range from single-lined, zero branch insertions, to insertions with two branched lines. The research aims to address the growing demand …
Published in Journal of Energy, Environment & Carbon Credits · Vol. 14, Issue 1, 2024 · pp. 2–7 Read article
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Enhanced Sunlight Intensity Measurement with Solar Tracking System
Abstract: Sunlight intensity measurement plays a crucial role in various applications, particularly in the context of solar energy utilization. However, traditional static acquisition devices often fail to provide precise measurements throughout the entire daylight period. This limitation necessitates the development of more advanced methodologies for accurate sunlight intensity assessment. In this studynn, we propose a novel approach utilizing a solar tracking system integrated with a measurement device to achieve precise sunlight …
Published in Journal of Alternate Energy Sources & Technologies · Vol. 15, Issue 1, 2024 · pp. 8–15 Read article
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Extraction of Copper from Electronic Waste (E-Waste): A Review
Abstract: The issue of electronic waste, or e-waste, is indeed a significant global concern with far-reaching environmental and health implications. As technology continues to advance and become more integrated into our daily lives, the disposal of obsolete or broken electronic devices has become a pressing issue. This waste not only contains valuable metals but also toxic substances, posing significant challenges for disposal and management. Improper disposal of e-waste is a significant …
Published in Journal of Materials & Metallurgical Engineering · Vol. 14, Issue 1, 2024 · pp. 14–27 Read article
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Cannabinoids as Nutritional Supplements: Exploring The Potential Health Benefits and Regulatory Landscape
Abstract: Cannabinoids, the bioactive compounds derived from the Cannabis sativa plant, have garnered increasing interest for their potential role as nutritional supplements. This abstract provides a succinct overview of cannabinoids as nutritional supplements. This review delves into the multifaceted aspects of cannabinoids, particularly their interaction with the endocannabinoid system (ECS) and their potential health benefits. The exploration begins by elucidating the intricate relationship between cannabinoids and the ECS, a vital regulatory …
Published in Emerging Trends in Metabolites · Vol. 1, Issue 1, 2024 · pp. 48–53 Read article
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InSilico Analysis and Homology Modeling of Tetrahydroprotoberberine Oxide involved in the Berberine Biosynthesis
Abstract: Objective: Berberine, a bioactive compound found in various plant species, exhibits diverse pharmacological properties with potential applications in pharmaceutical research. The biosynthesis of berberine involves several enzymatic steps, with (S)-tetrahydroprotoberberine oxidase playing a pivotal role. This study aimed to elucidate the structural and functional characteristics of (S)-tetrahydroprotoberberine oxidase to better understand its role in berberine biosynthesis and its potential biotechnological applications. Methods: Using bioinformatics tools and computational methods, the physicochemical …
Published in Emerging Trends in Metabolites · Vol. 1, Issue 1, 2024 · pp. 7–26 Read article
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ATM Network: A High-speed Communication Network
Abstract: Next-generation computers and communications will use asynchronous transfer mode (ATM). ATM networks employ compact, predetermined cells for message transmission, enabling them to efficiently utilize the same network for transmitting voice, video, and data across extensive distances. Most computer and telecommunications companies focus on ATM products and services. The building can also manage different and regular costs. Therefore, it is suitable for many vehicle types and has end-to-end encryption. ATM uses …
Published in Journal Of Network security · Vol. 12, Issue 2, 2024 · pp. 34–39 Read article
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Cracking the Code: A Study on Exploitable Weaknesses in QR Code Technology
Abstract: This study investigates the exploitable weaknesses inherent in quick response (QR) code technology, aiming to provide insights into potential security risks and mitigation strategies. QR codes, ubiquitous in modern society, serve various purposes ranging from marketing to authentication. However, their widespread utilization also renders them vulnerable to exploits by malicious actors. The research identifies common vulnerabilities such as data tampering, code injection, and phishing attacks, which can have significant consequences, …
Published in Journal Of Network security · Vol. 12, Issue 2, 2024 · pp. 9–17 Read article
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The Impact of Internet Accessibility and Infrastructure on Rural Online Shopping Behavior
Abstract: This study examines the crucial connection between rural consumers‘ online buying habits and internet availability and infrastructure in those places. The study finds that increased access to the internet has a beneficial impact on rural areas’ adoption of e-commerce. In these areas, trust and security concerns were found to be important determinants of online shopping behavior, in addition to demographic differences. The findings highlight the significance of overcoming internet-related difficulties …
Published in E-Commerce for Future & Trends · Vol. 11, Issue 2, 2024 · pp. 22–28 Read article
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Crystallinity of commercial carbon fibers from X-ray diffraction (XRD) studies
Abstract: Sized carbon fibers have commercial significance. Such carbon fibers serves has excellent reinforcing material with the polymer resin filler matrix leading to the formation of carbon fiber reinforced composites (CFRCs). Polarized carbon fibers find applications in the realms of health, energy, environment, defence, catalysis and smart materials. For brevities sake, the focus of the current research paper is only on the structural characterization of carbon fibers using XRD. The structure …
Published in International Journal of Photochemistry and Photochemical Research · Vol. 1, Issue 1, 2023 · pp. 17–27 Read article
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Assessment of Fire and Life Safety in Rural Settlements in India
Abstract: Fire incidents pose a significant threat to life and property in rural India, particularly in residences. Despite strides in urban fire safety, rural areas continue to face frequent fire incidents, posing significant risks to lives and properties. This paper presents a thorough review of existing literature on fire safety assessment in rural Indian settlements focusing on unique vulnerabilities specific to this context. In rural settings, various factors contribute to the …
Published in International Journal of Rural and Regional Development · Vol. 2, Issue 1, 2024 · pp. 47–53 Read article
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A Supervised Learning Approach for Toxic Comment Detection on Social Media Platforms
Abstract: Nowadays everyone uses social media platforms like X (formerly Twitter), Instagram, Facebook, etc. for various purposes. With the help of this, we share our opinions, ideas, and feelings. Generally, the datasets obtained from the internet are constructive; however, there is a significant proportion of toxic ones. The datasets are filtered to remove noise, and noise is removed in post-processing. The study initiates with the upload and preprocessing of a toxic …
Published in Journal of Mobile Computing, Communications & Mobile Networks · Vol. 11, Issue 2, 2024 · pp. 7–14 Read article
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GPT in Code Conversion: Achieving Agile, Accurate, and Effective Translations Across Programming Languages
Abstract: This comprehensive study meticulously investigates the intricacies and challenges inherent in the process of code conversion across a diverse range of programming languages. It provides an in-depth examination of select instances where code conversion poses significant challenges, and thoughtfully proposes innovative solutions to these complex problems. A key highlight of this research is the use of Generative Pre-trained Transformers (GPTs) like Copilot, which have proven to be instrumental in achieving …
Published in Journal of Artificial Intelligence Research & Advances · Vol. 11, Issue 2, 2024 · pp. 11–20 Read article
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FoodieBot: A Conversational Food Ordering Chatbot Using Node.js and Microsoft Bot Framework
Abstract: This article delves into the development of a food order chatbot, leveraging Node.js alongside the Microsoft Bot Framework. The burgeoning popularity of chatbots within the food industry stems from their capacity to streamline the ordering process while simultaneously enriching customer experiences. In this study, we explore the implementation process, features, and advantages associated with crafting a food order chatbot, utilizing Node.js as the backend programming language and the Microsoft Bot …
Published in Journal of Advancements in Robotics · Vol. 11, Issue 2, 2024 · pp. 14–18 Read article
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Comparative Evaluation of Fixed-Point Theorems Investigating Differences Among Conditions in Metric Spaces
Abstract: This paper provides a concise overview of metric spaces, their fundamental properties, and the idea of continuity as it pertains to these spaces, drawing parallels to uniform continuity and convergence. Also included is a review of previous research on metric space, its generalization, and practical outcomes from studies that utilized these spaces in various applications. We introduce a fixed point theorem for mixed monotone mappings in partially ordered metric spaces, …
Published in Research & Reviews: Discrete Mathematical Structures · Vol. 11, Issue 1, 2024 Read article