Search
276 articles for “Biological treatment”
-
Restoration of Degraded Agricultural Soils Through Organic Amendments and Sustainable Farming Practices
Abstract: This study investigates the efficacy of organic amendments and sustainable farming practices in restoring degraded agricultural soils, addressing a critical global challenge affecting food security and environmental sustainability. The research was conducted over three growing seasons on degraded semi-arid agricultural land, utilizing a randomized complete block design with five treatments: The following farming practices: pure control, organic amendments but market conventional farming practices, sustainable farming practices but market standard conventional, …
Published in Research and Reviews : Journal of Crop science and Technology · Vol. 13, Issue 3, 2024 · pp. 19–27 Read article
-
Changing Trends in Advanced Epithelial Ovarian Cancer - A Review
Abstract: Despite the advances in surgery and chemotherapy, the outcome of patients affected with advanced epithelial ovarian cancer continues to be poor. Now researchers are looking at ovarian cancer through newer perspectives so as to find better treatment modalities that can improve overall survival (OS). In this chapter, we have briefly reviewed the newer areas of research in epithelial ovarian cancer. We look at how better understanding of the molecular biology, …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 3, Issue 2, 2014 · pp. 1–7 Read article
-
Aquatic Ecosystems: A Review on Prospecting of Anticancer Molecules from Fungi & Other Microbes
Abstract: Marine biota; namely, actinomycetes, bacteria, fungi, microalgae, green algae, oceanic weeds, mangroves, and other extremophiles constitute about 90% of the oceanic biomass. The organisms are taxonomically diverse, biologically productive/active, and biochemically unique. These unique biochemiques may act as a great source for the discovery of new bioactive molecules, including anticancer drugs. The marines produce medicinally potent biochemicals; namely, sulfated saccharides, polyphenols, and, sterols. Only a few of these alkaloids have …
Published in International Journal of Fungi · Vol. 1, Issue 2, 2024 · pp. 1–22 Read article
-
Strategies for the Development and Optimization of Orally Disintegrating Tablets (ODTs) to Improve Bioavailability and Patient Compliance
Abstract: Background: Pharmaceutical scientists have developed Orally Disintegrating Tablets (ODTs) to advance patient drug acceptance and biological system availability through simplified medi-cation delivery especially for children and senior citizens and people who cannot swallow pills regularly. The oral disintegrating tablets dissolve in the mouth within thirty seconds or less (USP 701) while needing no additional liquid thus making them suitable for both emergency treatments. Objective: The research examines ODT development strategies …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 13, Issue 2, 2026 · pp. 50–64 Read article
-
RNA- Based Drug Delivery, Current Advances, Pharmaceutical Applications, and Future Perspectives
Abstract: RNA-based therapeutics have emerged as a transformative approach in modern medicine due to their ability to regulate gene expression with high specificity and precision. Advances in molecular biology, RNA chemistry, and nanotechnology have accelerated the development of diverse RNA modalities, including messenger RNA (mRNA), small interfering RNA (siRNA), microRNA (miRNA), antisense oligonucleotides (ASOs), and RNA aptamers. These therapeutics offer promising strategies for the treatment of cancer, genetic disorders, infectious diseases, …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 13, Issue 2, 2026 · pp. 27–41 Read article
-
Optimization of Variety-Vermicompost dose Synchrony on the Yield Traits of Hybrid cabbage (Brassica oleraceaevar. capitata L.) Varieties
Abstract: A season long field experiment was carried out to quantify the superimposing effect of varied vermicompost doses on the yield traits of selected hybrid cabbage (Brassica capitata var. L.) varieties during November 2018 to April 2019 production season. The treatments consisted of four vermicompost doses;0, 1.5, 2 and2.5t/h and three hybrid head cabbage varieties; K-500 F1, Landini F1 and Bandung F1 laid out in 3x4 factorial Randomized Complete Block Design …
Published in Research & Reviews : Journal of Agricultural Science and Technology · Vol. 9, Issue 3, 2020 · pp. 8–23 Read article
-
Innovations in Targeted Drug Discovery for Personalized Medicine
Abstract: Personalized medicine is revolutionizing modern healthcare by custoizing treatment plans to match an individual’s genetic makeup, protein expression, and metabomlic characteristics. Also referred to as precision medicine, this approach seeks to improve therapeutic outcomes, reduce adverse effects, and make efficient use of healthcare resources. The incorporation of various omics technologies—including genomics, proteomics, transcriptomics, metabolomics, and epigenomics—has greatly advanced our ability to understand disease biology and molecular variations specific to each …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 3, 2025 · pp. 19–41 Read article
-
Understanding Kameela's Importance In The Unani System Of Tibb: A Detailed Perspective
Abstract: Kameela or Kamala, a renowned Unani medicine, has been utilized by Unani physicians for centuries to effectively address Amraze Jildiya, commonly known as skin diseases. Its medicinal properties have been extensively documented in classical Unani texts. These perennial shrubs or small trees are widely distributed in tropical and subtropical regions, typically found at altitudes below 1,000 m. The pharmacological activities of Kameela encompass a broad spectrum, owing to its diverse …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 10, Issue 3, 2023 · pp. 16–22 Read article
-
Natural Antibodies Against Enteromicrobes and their Toxins for the Treatment of Rheumatoid Arthritis
Abstract: Autoimmune diseases (ADs) are thought to be brought on by the host immune system accidentally attacking and destroying its own tissue. “Molecular mimicry,” which asserts that antibodies against an infectious agent cross-react with a self-antigen possessing an identical or similar antigenic epitope, is a generally recognised theory to explain the pathogenic mechanism of ADs. This theory, however, was probably developed using false antibody assay data that was heavily impacted by …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 12, Issue 3, 2022 · pp. 1–12 Read article
-
Personalized Nutrition and Exercise: Pioneering the Path to Precision Medicine
Abstract: Preventive healthcare is about to undergo a major shift thanks to the personalised exercise and nutrition paradigm, which is based on precision medicine concepts. In order to create tailored recommendations for improving health outcomes and preventing chronic diseases, this article explores the integration of genetic profiling, metabolic evaluation, and lifestyle factors. A person's response to food and exercise depends heavily on genetic and metabolic variances, which emphasises the need of …
Published in Emerging Trends in Personalized Medicines · Vol. 1, Issue 2, 2024 · pp. 42–46 Read article
-
In Silico Tau Protein Kinase I Inhibitory Activity of Some Commercially Available Flavonoids
Abstract: Molecular docking is a frequently used tool in computer-aided structure-based rational drug design. Flavonoids are a group of natural products which exhibits various biological and pharmacological activities. The primary objective of this study was to investigate the tau protein kinase I inhibitory activity of flavonoids using in silico docking studies. Memantine, a known neuro-receptor antagonist is currently used in the treatment of Alzheimer’s disease (AD). In silico docking studies were …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 2, Issue 1, 2015 · pp. 6–12 Read article
-
Orthodontic Forces and Moments: Mathematical Basics
Abstract: Although clinicians have started using very refined and stabilized fixed orthodontic appliances. The physical concepts that form the foundation of orthodontic mechanics are the key in understanding how orthodontic appliances work. The principles are not unique to orthodontics but are basic to the science of static mechanics. Biomechanics is the stud y of mechanics as it affects the biologic systems. It is the application of mechanics to the tooth movements …
Published in Research and Reviews: A Journal of Dentistry · Vol. 6, Issue 2, 2015 · pp. 7–14 Read article
-
A Review on Unmasking Merkel Cell Polyomavirus: From Discovery to Cancer Driver
Abstract: Merkel cell polyomavirus (MCPyV) is a small, non-enveloped, circular double-stranded DNA virus belonging to the Polyomaviridae family, first characterized in 2008. Epidemiological data suggest widespread exposure, with seroprevalence rates approaching 80% in adults. While primary infection is typically asymptomatic, rare integration events in Merkel cells can initiate oncogenesis, yielding Merkel cell carcinoma (MCC), a neuroendocrine skin cancer with a five-year survival rate under 60%. This review integrates findings from six …
Published in International Journal of Virus Studies · Vol. 2, Issue 2, 2025 · pp. 6–11 Read article
-
Tinospora Cordifolia (Willd.) Hook.f. & Thomson: A Review on Herbal Formulations and Health Benefits
Abstract: India has a vast variety of medicinal plants utilised as natural medicines since prehistoric times. Herbal medicine was the main form of treatment earlier in the 20th century because neither antibiotics nor analgesics were readily available. Nowadays, natural plant products are becoming more significant in clinical research since they have no side effects and have greater pharmacological response than allopathic medications. Tinospora cordifolia (Giloy or Guduchi) is a climbing shrub …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 13, Issue 3, 2024 · pp. 14–19 Read article
-
Phytochemical Screening and Biological Activity of Pomegranate Extracts
Abstract: Pomegranates are renowned for their abundance of bioactive compounds that exhibit potent antioxidant, anti-inflammatory, and antimicrobial properties, making them a subject of growing interest in natural medicine. This study aimed to compare the biological activities of ethanolic extracts derived from different parts of the pomegranate plant—specifically, the bark, peel, and leaves. A comprehensive investigation was conducted to evaluate their phytochemical composition and assess their antimicrobial, antioxidant, and anticancer properties. The …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 12, Issue 2, 2025 · pp. 64–79 Read article
-
An Insight into Childhood Malignancy
Abstract: Childhood cancers represent a significant public health concern, affecting a vulnerable population with unique biological and developmental characteristics. The aim of this article is to describe the main causes and different types of malignancies in childhood. By understanding the contributing factors towards malignancy in childhood one can plan for the preventive measures and early diagnosis and treatment modalities can be adopted. Even though the treatment patterns have improved, people are …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 13, Issue 1, 2024 · pp. 07–12 Read article
-
Harnessing Honeybee Venom For Cancer Treatment: A Natural Remedy In Oncology
Abstract: Honeybee venom (HBV) has harvested significant attention as a promising natural compound with therapeutic potential in cancer treatment. This review investigates deeply into the current scientific understanding of honeybee venom, focusing on its anticancer mechanisms, molecular interactions, and potential clinical applications. Honeybee venom comprises various bioactive components, including melittin, apamin, phospholipase A2, and other peptides, which exhibit a wide range of biological activities. Recent research has demonstrated its ability to …
Published in Research and Reviews: A Journal of Toxicology · Vol. 15, Issue 1, 2025 · pp. 10–14 Read article
-
Artificial Intelligence in Microbiological Research: Methods, Applications and Implications
Abstract: Artificial Intelligence (AI) is revolutionising microbiological research by enabling the rapid analysis of complex biological data and improving the accuracy, efficiency, and reliability of scientific investigations. Recent advances in machine learning, deep learning, and bioinformatics have transformed AI into a powerful tool for studying microorganisms, their genetic composition, evolutionary patterns, and interactions with hosts and the environment. AI-driven computational models can process large and complex datasets far more efficiently than …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 16, Issue 2, 2026 · pp. 22–36 Read article
-
Recent Update on Advanced Drug Delivery System
Abstract: Over the past decade, there has been a growing interest in the use of artificial intelligence (AI) technology for analysing and interpreting biological or genetic data, accelerating drug discovery, and identifying selective small-molecule modulators or rare molecules in addition to predicting their behaviour. The use of artificial neural networks (ANNs) for the rapid analysis of massive amounts of data, the development of novel hypotheses and treatment plans, the prediction of …
Published in International Journal of Advance in Molecular Engineering · Vol. 1, Issue 1, 2023 · pp. 22–30 Read article
-
Metabolites in Modern Medicine: Decoding the Future of Health and Diseases
Abstract: The end products of many metabolic processes in cells are called metabolites. Each reaction contributes a specific metabolite. Metabolites act as fingerprints of on-going biological processes. Constant changes in cellular composition due to both environmental and internal factors. By analysing the types and presence of metabolites, scientists can effectively reconstruct the inner workings of a cell or organism. In the past, analysing metabolites was a slow and tedious process, often …
Published in Emerging Trends in Metabolites · Vol. 1, Issue 2, 2024 · pp. 1–13 Read article