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224 articles for “Disease Modeling”
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Analysis of White Matter, Gray Matter, and Cerebrospinal Fluid Alterations in Neurological Disorders: A Deep Learning Approach
Abstract: This paper investigates the role of white matter (WM), gray matter (GM), and cerebrospinal fluid (CSF) alterations in the pathophysiology of neurological disorders, including Alzheimer’s disease, Parkinson’s disease, schizophrenia, and epilepsy. By leveraging advanced deep learning methodologies, we aim to automate the segmentation and analysis of brain structures from MRI scans, enabling a more detailed and precise evaluation of their roles in disease progression. These techniques allow for the identification …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 14, Issue 3, 2024 · pp. 21–27 Read article
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Use of the Computer Statistics in Oncology
Abstract: Currently, the use of computer statistics and computer statistical modeling in oncology for obtaining an accurate diagnosis, determination of the choice of treatment method and its correction in the process of ongoing treatment, prediction of the outcome of the disease, and evaluation of the effectiveness of the chosen treatment tactics is a decisive factor. The use of computer statistics, based on an adapted scientific and statistical package of the SSP …
Published in Research & Reviews : Journal of Statistics Read article
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GenChrome-ML: A Machine Learning Framework for Early Detection of Chromosomal Disorders Using Genomic Data
Abstract: The increasing burden of chronic disease and cancer demands innovative, more rapid and effective diagnostic tools in the field of healthcare. The majority of current diagnostic tools are dependent upon clinical symptomology and manual evaluation, leading to delays in early detection and treatment. The development of artificial intelligence (AI) and machine learning (ML), in recent years, has offered opportunities for the enhancement of disease prediction, diagnosis and personalization of treatment …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 4, Issue 2, 2026 Read article
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Revolutionizing Plant Disease Detection: A Comprehensive Review
Abstract: Rise in population demands more food production but the diseases in plants contribute to loss. The advancement in agricultural field has a remarkable effect in detecting plant diseases. These diseases will have a major impact on the quality of plant and yield and hence can destroy the entire plant if they are not controlled on time. To reduce disease-related losses, it is necessary to identify different types of diseases and …
Published in International Journal of Advance in Molecular Engineering · Vol. 1, Issue 2, 2023 · pp. 44–55 Read article
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Formulation Challenges in Long-acting Injectable Small Molecules: Emerging Strategies and Perspectives
Abstract: Long-acting injectable (LAI) formulations represent a transformative approach in pharmacotherapy, particularly for conditions demanding sustained drug exposure over weeks to months. Although biologics have dominated this space historically, the adaptation of LAI technology to small molecules presents a distinct and complex set of challenges rooted in physicochemical properties, manufacturing scalability, and regulatory expectations. This review systematically addresses the principal formulation barriers encountered in developing LAI small-molecule products, including aqueous solubility …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 13, Issue 2, 2026 Read article
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A Data-Driven Analysis of Machine Learning Classification Models for Reliable Crop Yield Prediction
Abstract: The adoption of ML technologies in agriculture is reshaping farming practices, empowering producers to make informed, data-oriented decisions that improve yields, sustainability, and long-term resilience. In mango cultivation, ML analyzes data from weather, soil, and pests to optimize irrigation, fertilization, and pest control. Predictive analytics help forecast ideal farming practices, minimizing resource wastage and improving yield. Real-time monitoring and image-based disease detection allow timely interventions to maintain plant health and …
Published in Research and Reviews : Journal of Crop science and Technology · Vol. 15, Issue 1, 2026 · pp. 12–17 Read article
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Exploring the Development of AI Models Using Open-Source Tools to Predict Patient Outcomes and Optimize Treatment Plans
Abstract: Integrating artificial intelligence (AI) into healthcare offers a transformative opportunity to enhance patient care and clinical decision-making. Through the use of predictive analytics, AI can significantly enhance the accuracy of outcome predictions and assist in developing personalized treatment plans that cater to each patient’s specific needs. This paper delves into the development of AI models using open-source tools, which are increasingly favored for their accessibility, collaborative nature, and capacity for …
Published in Journal of Open Source Developments · Vol. 11, Issue 3, 2024 · pp. 37–49 Read article
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Gene Therapy 2.0: Harnessing Cutting-Edge Technologies for Precision Medicine
Abstract: Somatic gene therapy has become the standard form of gene therapy; this creates the Gene Therapy 2.0 era. This new and distinct time consists in the new-generation genome-editing tools and markers, more efficient systems for gene delivery, and personalized medicine approaches that raise the efficacy and safety of the treatment. Base and prime editing are two types of CRISPR-based gene editing tools have provided high precision and reduced off-target effects …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 3, Issue 2, 2025 Read article
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The Rise of Fractional Calculus: Novel Applications in Engineering and Biological Systems
Abstract: Fractional calculus (FC) is an advanced mathematical framework that generalizes the classical concepts of differentiation and integration to non-integer, or fractional, orders. This extension of traditional calculus allows for the modeling of complex dynamic systems that exhibit behavior not easily captured by integer-order differential equations. Over the last few decades, fractional calculus has seen a rapid rise in popularity, particularly in applied mathematics, engineering, and biological sciences, due to its …
Published in Recent Trends in Mathematics · Vol. 1, Issue 2, 2024 · pp. 7–11 Read article
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Magnetic and Radioactive Nanoparticles for Improved Theranostics and AI Assisted Radiation Therapy
Abstract: Nanoparticles based therapeutic and theranostics technique is becoming an active area of research in nanomedicine. The sensitivity, biocompatibility, and stability of magnetic and radioactive nanoparticles determine their functionality. This research highlights the impacts of magnetic and radioactive nanoparticles on therapeutic techniques namely, cell therapy, gene therapy, and tissue regeneration. Then, it is intended to brief a principal role of these therapeutic techniques to envisage theranostics medicine and radiation therapy using …
Published in International Journal of Advance in Molecular Engineering · Vol. 3, Issue 2, 2025 · pp. 10–21 Read article
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A Study to Determine the Impact of a Structure Teaching Program on the Knowledge of Needle Stick Injury Among Hospital Staff Nurses
Abstract: Needle stick injuries occur when needles accidentally puncture the skin, posing a risk to individuals working with hypodermic syringes and other needle equipment, particularly in healthcare settings. These injuries are recognized as occupational hazards in the medical field and raise concerns about the potential transmission of blood-borne illnesses, including hepatitis B virus (HBV), hepatitis C virus (HCV), and human immunodeficiency virus (HIV). Although the immediate physical effects of needle stick …
Published in International Journal of Community Health Nursing And Practices · Vol. 1, Issue 2, 2023 Read article
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Innovations in Targeted Drug Discovery for Personalized Medicine
Abstract: Personalized medicine is revolutionizing modern healthcare by custoizing treatment plans to match an individual’s genetic makeup, protein expression, and metabomlic characteristics. Also referred to as precision medicine, this approach seeks to improve therapeutic outcomes, reduce adverse effects, and make efficient use of healthcare resources. The incorporation of various omics technologies—including genomics, proteomics, transcriptomics, metabolomics, and epigenomics—has greatly advanced our ability to understand disease biology and molecular variations specific to each …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 3, 2025 · pp. 19–41 Read article
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Diabetes Prediction Using ML Techniques
Abstract: Diabetes mellitus, commonly referred to as diabetes, denotes a cluster of prevalent endocrine disorders characterized by persistent elevated levels of blood sugar. Diabetes is classified into two main types: type 1 and type 2. Type 1 diabetes arises when the body is unable to produce insulin, while type 2 diabetes involves either insulin resistance or insufficient insulin production. Early detection and intervention are essential to reduce its harmful impacts. The …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 11, Issue 3, 2024 · pp. 1–9 Read article
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Parkinson’s Disease Detection on Spiral Images Using CNN with Meta-Classifiers
Abstract: In this work, we provide a detailed method for identifying Parkinson’s Disease (PD) by integrating Convolutional Neural Network (CNN) and meta-classifiers. Through the utilization of a varied dataset consisting of handwritten spiral images, our methodology demonstrates commendable accuracy across a range of models. Specifically, our CNN model with meta-classifiers surpasses alternative approaches, achieving an impressive accuracy rate of 95.07%. By utilizing pre-established VGG16 and ResNet50 architectures as bases, the region-based …
Published in Journal of Computer Technology & Applications · Vol. 16, Issue 1, 2025 · pp. 55–66 Read article
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AI Approaches in Gait and Posture Analysis: A Review
Abstract: This review synthesizes current research on the application of artificial intelligence (AI) in gait and posture analysis, focusing on methodologies, algorithms, and clinical applications. It examines the use of machine learning (ML) and deep learning (DL) techniques to extract relevant features from sensorderived data, offering objective, and automated assessments that surpass traditional methods. A systematic literature review was conducted, analyzing studies that utilized AI for gait and posture analysis with …
Published in Research and Reviews : Journal of Computational Biology · Vol. 14, Issue 3, 2025 · pp. 1–3 Read article
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Melanoma Skin Cancer Detection Using Deep Learning
Abstract: Cancer as one of the major diseases rank in the World is still very challenging to diagnose and treat hence need for the technological advancements. Chemotherapy, radiation, as well as surgery therapies have several drawbacks including non-selective action, damage to healthy tissues, and multi-drug resistance. Smart nano-theranostics, an advanced integration of nanotechnology with diagnostic and therapeutic modalities, offers a next-generation approach for precision oncology. Thus, the development of multifunctional nanoparticles …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 14, Issue 2, 2025 Read article
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Advancements in Drug Design Technology and Its Impact on COVID-19 Treatment
Abstract: The deadly coronavirus disease 19 (COVID-19) pandemic has recently spread, raising concerns about global health. The search for novel therapeutic compounds is made more necessary by the persistent problem of the absence of licensed medications or vaccinations. By saving money and time, computer-aided drug design has sped up the process of finding and developing new drugs. The structured-based and ligand-based drug discovery subcategories of computer-aided drug design (CADD) are the …
Published in International Journal of Virus Studies · Vol. 1, Issue 1, 2024 · pp. 1–15 Read article
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AI-Enabled Linear Regression Model for Spectroscopic Milk Adulteration Analysis
Abstract: Milk adulteration poses a serious threat to public health and quality assurance in the dairy industry. This requiring rapid, reliable, and non-destructive detection techniques. This study presents a linear regression-based analytical model for identifying and quantifying milk adulteration using spectroscopic data. Spectral measurements of milk samples, including both pure and adulterated variants were acquired using spectroscopic techniques at relevant wavelengths.Blending of other components in pure milk , is specifically called …
Published in Research & Reviews : Journal of Food Science & Technology · Vol. 15, Issue 1, 2026 · pp. 28–42 Read article
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Cardiovascular Illness Detection and Categorization with Innovative Neural Networks
Abstract: Health-related problems are increasingly prevalent in modern-day societies and are significantly shaped by a multitude of factors encountered in everyday life. Among these, cardiovascular diseases have emerged as one of the primary causes of death on a global scale, posing serious challenges to public health systems. In response to this growing concern, the present study proposes a machine learning-based framework that is not only highly effective but also reliable and …
Published in Journal of Artificial Intelligence Research & Advances · Vol. 12, Issue 2, 2025 · pp. 21–30 Read article
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Crop Yield Prediction Using Machine Learning Algorithm Based on Climate Variables
Abstract: India's economy is based primarily on agriculture, as over 50% of the country's population depends on it for their livelihood. The long-term viability of agriculture is seriously threatened by variations in the weather, climate, and other environmental factors. Because machine learning provides tools for decision assistance in agricultural yield prediction, including guidance on which crops to plant and when to plant them during the growing season, it is essential to …
Published in International Journal of Cheminformatics · Vol. 1, Issue 2, 2023 · pp. 49–52 Read article