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169 articles for “Validation”
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QSAR Modeling Techniques: A Comprehensive Review of Tools and Best Practices
Abstract: Quantitative Structure–Activity Relationship (QSAR) modeling has become an essential tool in drug discovery, toxicity assessment, and environmental chemistry. By correlating chemical structure with biological activity or toxicity, QSAR enables the prediction of compound behavior without extensive experimental testing. This approach not only saves time and resources but also supports ethical practices by reducing reliance on animal studies. The evolution of QSAR from basic linear models to advanced machine learning and …
Published in International Journal of Cheminformatics · Vol. 3, Issue 1, 2025 · pp. 56–63 Read article
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Optimization of Process Parameters for AISI 304 Using Micro-EDM Drilling Process Through Response Surface Method
Abstract: The increasing demand for micro-parts in high-tech products, such as micro-electromechanical systems (MEMS) applications and micro-electronic devices, has driven significant advancements in micromachining technologies. Among the various micromachining processes, the fabrication of accurate microholes and pins is critical for the performance and reliability of miniature components. Micro-hole drilling plays a vital role by enabling the production of deep holes with excellent straightness, roundness, and surface quality. It is widely used …
Published in International Journal of Manufacturing and Production Engineering · Vol. 3, Issue 1, 2025 · pp. 37–47 Read article
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The War's Economic Effects in the Twenty-First Century, Both Locally and Internationally
Abstract: The essay looks at how wars in the twenty-first century have affected the economy both theoretically and practically. The idea of the "military economy" is emphasized. Analysis is done on the dynamics of military spending. The causes and forms of conflicts that have taken place in the past and are happening now are explained. Researching the economic effects of Russia's war in Ukraine is emphasized. The pre-war evaluation of nations' …
Published in International Journal of Trends in Humanities · Vol. 2, Issue 2, 2025 · pp. 14–21 Read article
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Impact of Training Program on Recent Innovations in Oncology Among Nursing Professionals
Abstract: Introduction: In recent years, there have been significant advancements and trends in the field of oncology treatment in India. This study aimed to evaluate impact of training program on knowledge regarding recent innovations in oncology among nursing professionals. After ethical approval, a pre-experimental, one group pretest- post-test design was used to conduct this research at anursing college of Punjab. Methods: The sample was selected using the total enumerative sampling technique. …
Published in International Journal of Oncological Nursing and Practices · Vol. 3, Issue 1, 2025 · pp. 9–14 Read article
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Eye Disease Classification Using K-means Clustering Algorithm and Ensemble Classification Approach
Abstract: In this study, we present a comprehensive approach for the classification of eye diseases, specifically targeting normal, cataract, glaucoma, and diabetic retinopathy conditions. This research uses a dataset from Kaggle, which provides a wide and varied collection of retinal images to ensure good representation. The methodology encompasses advanced image processing and machine learning techniques to ensure accurate diagnosis and prediction. The preprocessing phase involves a series of image enhancement techniques …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 2, 2025 · pp. 15–27 Read article
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Machine Learning Approach to Predict the Performability and Emissions of Diesel Engine Fueled with Doped Biodiesel Blend
Abstract: Enhancing the performability and emission characteristics of diesel engines has been a difficult task in light of growing concerns about global warming and other negative effects, as diesel accounts for 70% of global energy demand. In this study, engine performance and exhaust emissions for various fuel blends were thoroughly evaluated using machine learning techniques to predict engine emission and performance behavior. We focused on biodiesel blend and nanoparticle additive concentration …
Published in International Journal of Mechanical Dynamics and Systems Analysis · Vol. 3, Issue 1, 2025 · pp. 1–12 Read article
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Dynamic Modeling and Simulation of Multi-Body Mechanical Systems: A Comprehensive Review of Methods, Tools, and Applications
Abstract: The dynamic modeling and simulation of multi-body mechanical systems (MBS) form a cornerstone in modern mechanical engineering, enabling in-depth analysis of the kinematic and kinetic behaviors of interconnected rigid and flexible components. MBS are foundational to a range of critical applications, from automotive suspensions and aerospace mechanisms to robotics and biomechanical structures. As system complexity and performance requirements increase, accurate and scalable modeling techniques are essential for both design validation …
Published in International Journal of Mechanical Dynamics and Systems Analysis · Vol. 3, Issue 1, 2025 · pp. 35–42 Read article
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Enhancing Glaucoma Diagnosis with Deep Learning: A Study Using ResNet-50 and DenseNet-121
Abstract: Glaucoma is a leading cause of irreversible blindness worldwide, mainly resulting from progressive optic nerve damage, often related to elevated intraocular pressure. Early detection is essential to prevent vision loss, but traditional diagnostic methods rely on specialized equipment and trained professionals, making large-scale screening difficult. This study uses a publicly available fundus imaging dataset to explore the effectiveness of deep learning models for glaucoma detection. These datasets provide medical images, …
Published in International Journal of Brain Sciences · Vol. 2, Issue 2, 2025 · pp. 9–18 Read article
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Navigating the Challenges of COVID-19: A Guide for Mental and Behavioural Health
Abstract: The COVID-19 epidemic has posed unique encounters globally, impacting various aspects of daily life, including mental and behavioral health. The present study attempts to prepare a guide with ways and means to navigate the challenges of the COVID-19 pandemic. This guide provides comprehensive insights and strategies for individuals to navigate these challenges effectively. The study began by addressing the psychosomatic effect of the pandemic, such as increased anxiety, depression, PTSD, …
Published in International Journal of Behavioral Sciences · Vol. 2, Issue 2, 2025 · pp. 1–15 Read article
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Need of a Comprehensive and Feasible Psychometric Test in the Assessment of Perinatal Mental Health - A Systematic Review
Abstract: The perinatal period is a period of happiness as well as hardships. A woman undergoes many psychological changes during this period which makes her prone to mental health disorders that can be detrimental to the health of the women and her child. Its essential to detect these disorders as early as possible and hence a psychometric test or tool which is easy to administer and interpret is needed. Globally various …
Published in International Journal of Behavioral Sciences · Vol. 3, Issue 1, 2026 · pp. 104–111 Read article
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Pelvic Floor Muscle Strengthening in Antenatal Period Among Primigravida Cases at Jorhat, Assam
Abstract: Aim: The study aimed to evaluate the effectiveness of pelvic floor muscle (PFM) strengthening exercises during the antenatal period among primigravida women in Jorhat, Assam, with a focus on improving pelvic floor muscle strength and its impact on pregnancy outcomes. Purpose: To assess whether pelvic floor muscle exercises (specifically Kegel exercises) can enhance PFM strength in pregnant women, using the Modified Oxford Grading Scale (MOS), and to compare these effects …
Published in International Journal of Midwifery Nursing And Practices · Vol. 3, Issue 1, 2025 · pp. 35–42 Read article
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Lifestyle Factors and Perceptions of Diabetes Among Individuals in North India
Abstract: Background: Diabetes mellitus is influenced by a complex interplay of genetic, environmental, and lifestyle factors. In North India, unique socio-cultural and dietary patterns shape individual behaviors and perceptions toward diabetes. Understanding these lifestyle choices and cultural beliefs is critical for designing interventions that improve adherence to medical treatment and promote healthier outcomes. Methods: A cross-sectional survey was conducted among 1,500 individuals diagnosed with diabetes across selected urban and rural districts …
Published in International Journal of Tropical Medicines · Vol. 2, Issue 2, 2025 · pp. 1–7 Read article
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Mathematical Modeling of Epidemics Using Stochastic Differential Equations: A Review
Abstract: The accurate modeling of infectious disease dynamics is crucial for predicting outbreaks and informing public health interventions. While deterministic models such as the SIR (Susceptible-Infected-Recovered) framework have traditionally been used to understand disease transmission, they often fail to account for the randomness inherent in real-world scenarios. Disease spread is influenced by numerous uncertain factors, including individual behavioral changes, environmental fluctuations, and imperfect data reporting. These uncertainties can significantly impact model …
Published in Recent Trends in Mathematics · Vol. 1, Issue 2, 2024 · pp. 1–6 Read article
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Molecular Docking Analysis of Berberis aristata Phytocompounds as Potential Growth Factor Receptor Blockers in Cancer Therapy
Abstract: Middle-aged and older women are susceptible to breast cancer (BC), a potentially fatal condition. When breast cancer is diagnosed, the median age is 62. Breast cancer diagnoses in women under 45 are comparatively uncommon, whereas the bulk of breast cancer diagnoses occur in women 62 and older. Growth factor receptors are interesting therapeutic targets because of their critical role in the pathophysiology of cancer. Vascular endothelial growth factor receptors (VEGFR-2) …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 3, Issue 2, 2025 · pp. 1–10 Read article
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Exploring Oroxylum indicum Phytochemicals as VEGFR-2 Inhibitors: A Molecular Docking Approach for Cancer Management
Abstract: Cancer is still a major health problem around the world and is one of the top causes of death. A protein called VEGFR-2 (vascular endothelial growth factor receptor 2) is important because it helps blood vessels grow by supporting the survival, movement, and growth of certain cells. This process is essential for tumors to grow and spread to other parts of the body. This study focused on evaluating the binding …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 3, Issue 2, 2025 · pp. 48–62 Read article
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A Systematic Review on Leukemia Detection and Classification Techniques Using Gene Expression
Abstract: Early diagnosis of genetic diseases is crucial for effective treatment, especially in the case of Leukemia, a type of blood cancer characterized by abnormal proliferation of white blood cells. This paper presents a systematic review of recent computational techniques for the detection and classification of Leukemia using gene expression data obtained from DNA microarray analysis. The study explores diverse methodologies including machine learning (ML), deep learning (DL), and bio-inspired algorithms …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 3, Issue 2, 2025 Read article
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Advancing Cancer Vaccine Development through CRISPR/Cas9 Technologies and Future Opportunities
Abstract: The advent of CRISPR/Cas9 genome editing has revolutionized the cancer immunotherapy market, offering unprecedented precision and versatility in the development of next-generation cancer vaccines. This review examines how CRISPR technologies are being integrated into various stages of cancer vaccine development including neoantigen discovery, dendritic cell engineering, cancer cell reprogramming, and tumor microenvironment modulation. In the area of neoantigen discovery, CRISPR enables rapid identification and validation of tumor-specific mutations, thereby supporting …
Published in International Journal of Vaccines · Vol. 2, Issue 2, 2025 Read article
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Dr. Somenath Dutta, Discoverer of Micro-RNA (MiRNA) Therapeutic to Prevent Harmful Zika Virus for Liver Cancer: A Scientometric Portrait
Abstract: Dr. Somenath Dutta allies Rahul is a global recognized scientist for his outstanding recent discovery of “miRNA therapeutics for the Zika virus” at the age of 26 years, which can be cured Liver Cancer and allied health problems due to Zika virus disease. This study covers his 12 publications in variety of forms including 07 journal articles (59%), 03 conference papers (25%), 01 dissertation, and 01-chapter paper during 2019-2024. All …
Published in International Journal of Virus Studies · Vol. 2, Issue 2, 2025 · pp. 22–36 Read article
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Unveiling the Relationship Between Anxiety and Self-Esteem in Adult Populations
Abstract: The purpose of this study was to investigate the intricate connection between anxiety and self-esteem in adult Delhi National Capital Region (NCR) residents. A purposive sample approach was employed to select seventy people from this region. The study measured participants' self-worth and gathered pertinent background data using the Rosenberg Self-Esteem Scale (RSES) and a sociodemographic data form. In the data analysis, a t-test was employed to assess significant differences between …
Published in International Journal of Children · Vol. 2, Issue 2, 2025 · pp. 35–44 Read article
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Examining the Relationship Between Academic Stress, Maladaptive Perfectionism and Trauma-Related Responses Among University Students
Abstract: Academic stress is a significant concern among university students, frequently contributing to maladaptive perfectionism and trauma-like responses. While perfectionism can enhance performance, its maladaptive variant may be exacerbated by academic stress which can induce trauma-like responses. This study investigates the correlation between academic stress, maladaptive perfectionism and trauma-like responses. Validated self-report measures were used in a quantitative, correlational study involving 101 university students. Linear regression analysis and Kendall’s Tau-B correlation …
Published in International Journal of Education Sciences · Vol. 3, Issue 1, 2026 · pp. 145–154 Read article