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136 articles for “Clinical validation”
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Clinical Evaluation of Efficacy of a Polyherbal Unani Formulation (Mentioned in Makhzan-Ul-Ilaj) in the Management of Warm-e-Lauzatain-Haad (Acute Tonsillitis)
Abstract: Background: Warm-e-Lauzatain-Haad (Acute Tonsillitis) is an inflammatory condition of the palatine tonsils characterized by throat pain, fever, odynophagia and general discomfort. It is particularly common among adolescents and young adults and contributes substantially to outpatient visits and missed academic or workdays. In Unani medicine Warm-e-Lauzatain is described as a hot inflammatory swelling arising from deranged humors, exposure to irritants or descending catarrhal matter. Classical Unani texts including Makhzan-ul-Ilaj, advocate the …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 15, Issue 1, 2026 · pp. 13–22 Read article
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Practice and Preference of Tooth Notation Systems Among the General Dental Practitioners in Vadodara City
Abstract: Introduction: There are several different tooth notation systems used by dentists for associating data to a selected tooth. Several types amongst them can be named as Universal system, Bosworth system, Navy system, World dental federation system, Zsigmondy and Palmer system and Federation Dentaire Internationale (FDI). But there is no single tooth notation system used worldwide. All notation systems introduced up to now are used as per native wants and convenience. …
Published in Research and Reviews: A Journal of Dentistry · Vol. 13, Issue 3, 2022 · pp. 30–34 Read article
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Efficacy of a Unani Formulation in Internal Hemorrhoids (Bawaseer-E-Ghaira)
Abstract: Haemorrhoids are one of the most common anorectal disorders encountered in the general population. Haemorrhoids are the most common (30‑40%) cause of lower GI bleeding in India. The present study has been designed to validate the effect of Unani formulation in the management of Bawaseer-e-ghaira (Internal haemorrhoids of Grade-I and II degree) on scientific parameters. The ingredients of Unani formulation are Bisfaij, Zarnabad, Rasaut, Muqil, Maghz tukhm Neem and Gulab. …
Published in Research and Reviews : Journal of Surgery · Vol. 9, Issue 1, 2020 · pp. 1–7 Read article
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A Review of Drug Design Techniques Assisted by Computers to Combat Diabetes
Abstract: Diabetes mellitus is a global health concern characterized by chronic hyperglycemia and associated complications. The creation of innovative medicines with enhanced efficacy and safety profiles continues to be a top focus, notwithstanding improvements in treatment. A useful method in drug development, computer-aided drug design (CADD) makes it easier to identify possible therapeutic candidates and optimise lead molecules. An extensive synopsis of CADD tactics used in the fight against diabetes is …
Published in Emerging Trends in Personalized Medicines · Vol. 2, Issue 1, 2025 · pp. 1–10 Read article
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AI in Healthcare: Drug Delivery in Tuberculosis
Abstract: Tuberculosis (TB) , mainly caused by Mycobacterium tuberculosis, remains a major global health burden, accounting for millions of new infections and deaths each year. Although progress has been made in diagnosis and treatment, the growing threat of multidrug-resistant (MDR) and extensively drug-resistant (XDR) TB makes disease control increasingly difficult. Conventional diagnostic approaches such as chest X-rays, sputum smear microscopy, and culture methods continue to play an important role, but they …
Published in Trends in Drug Delivery · Vol. 13, Issue 1, 2026 · pp. 9–17 Read article
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Postprandial Elevation of Body Temperature – A Diagnostic Tool for Diq (Tuberculosis)
Abstract: AbstractDiq (tuberculosis) is one of the oldest diseases. The writings from different civilizations represent its clues. The man has been striving to know, to identify, to diagnose, to cure, to prevent and to eradicate this emaciating disease. All renowned Unani physicians have paid due attention towards the description of this disease. They are of the opinion that Diq is a condition in which Hararat Ghair Tabayee (abnormal heat) is associated …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 2, Issue 2, 2013 · pp. 37–44 Read article
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Application of Guided Surgery Concepts in the Programming and Intraoperative Management of Apicoectomies using a Surgical Template: A Case Report
Abstract: Apicoectomies are Endodontic Microsurgical procedures that require high precision. However, the state-of-the-art method currently used provides for a certain degree of imprecision as it heavily relies on the clinician’s judgment and experience with the sole aid of preliminary radiographic investigations. This clinical study aims to apply the Surgical Guided Approach, frequently used in Implantology, to Apicoectomies, thereby ensuring higher precision and, therefore, a lower amount of bone tissue loss as …
Published in Research and Reviews: A Journal of Dentistry · Vol. 13, Issue 3, 2022 · pp. 14–21 Read article
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The Contribution of A. I. in Pharmaceutical Software
Abstract: The integration of Artificial Intelligence (AI) in pharmaceutical software has significantly transformed drug development, regulatory processes, and clinical management. AI-powered tools are revolutionizing data analysis, predictive modeling, and decision-making, enhancing the efficiency and accuracy of drug discovery and development. This article explores the multifaceted contributions of AI to pharmaceutical software, including its applications in drug screening, personalized medicine, clinical trial optimization, and regulatory compliance. Additionally, we examine how AI is …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 3, Issue 1, 2025 · pp. 1–10 Read article
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Gold Nanoparticle Size, Biodistribution, and Toxicity: Insights from DualEnergy CT
Abstract: Dual-energy and spectral computed tomography (CT) have emerged as powerful platforms for noninvasive, quantitative mapping of nanoparticle biodistribution in vivo. By exploiting the energy-dependent attenuation profiles of high-atomic-number (high-Z) materials, these systems enable material decomposition and element-specific imaging, thereby distinguishing nanoparticle signals from those of soft tissues and conventional iodinated contrast agents. Photon-counting spectral CT further enhances this capability by binning individual photons into multiple energy channels, improving spatial resolution, …
Published in Nano Trends – A Journal of Nano Technology & Its Applications · Vol. 28, Issue 2, 2025 · pp. 22–34 Read article
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A Comparative Review on Abelmoschus palianus and Barleria mysorensis: Phytochemical Constituents, Pharmacological Potentials, and Ethnobotanical Significance
Abstract: Medicinal plants have long served as invaluable resources for treating human ailments, with countless species still awaiting scientific exploration and validation. Abelmoschus palianus and Barleria mysorensis are two such botanicals with rich ethnomedicinal heritage but limited pharmacological characterization. This review presents a detailed comparative analysis of these two species, examining their botanical descriptions, geographic distribution, traditional applications, phytochemical constituents, pharmacological properties, toxicological profiles, and therapeutic potential. Abelmoschus palianus, native to …
Published in Research & Reviews : Journal of Herbal Science · Vol. 14, Issue 3, 2025 · pp. 7–13 Read article
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Enhanced Multimodal Disease Prediction Using Hybrid Ensemble Learning and AutoML Techniques
Abstract: The integration of hybrid ensemble learning and automated machine learning (AutoML) is revolutionizing disease prediction by addressing the complexity, imbalance, and high dimensionality inherent in medical datasets. This paper proposes an advanced pipeline that combines diverse ensemble learning models with AutoML-based optimization to predict chronic diseases such as kidney diseas-e, Parkinson’s disease, and lung cancer. Publicly available datasets from UCI and PhysioNet repositories were preprocessed using outlier removal, normalization, and …
Published in Research and Reviews : Journal of Computational Biology · Vol. 15, Issue 1, 2026 · pp. 10–20 Read article
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Pharmacophore mapping, 3D QSAR, docking, and ADME prediction studies of novel Benzothiazinone derivatives
Abstract: Background Tuberculosis is a major public health concern worldwide which is caused by Mycobacterium tuberculosis. DprE1 (Decaprenyl Phosphoryl Ribose 2’- Epimerase) is the most challenging target for development of novel anti- tubercular agents because it is a small protein and located into cytoplasmic membrane. So, novel anti-TB drugs did not bound effectively with it. DprE1 catalyzes the oxidation of the 2’ hydroxyl group of DPR (Decaprenyl Phosphoryl D- Ribose) …
Published in International Journal of Antibiotics · Vol. 1, Issue 1, 2024 · pp. 59–82 Read article
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Early Alzheimer’s Disease Prediction Using Vision Transformers and Attention-Guided MRI Analysis
Abstract: Alzheimer’s Disease (AD) continues to be a major global health concern, with early detection being crucial for effective intervention. While conventional machine learning and convolutional neural network (CNN) approaches have made notable progress in automated AD diagnosis using MRI data, they often struggle with capturing long-range dependencies and maintaining spatial contextual awareness. In this research, we propose a novel framework using Vision Transformers (ViTs) for early Alzheimer’s prediction from 3D …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 16, Issue 1, 2026 · pp. 30–40 Read article
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Dr. Somenath Dutta, Discoverer of Micro-RNA (MiRNA) Therapeutic to Prevent Harmful Zika Virus for Liver Cancer: A Scientometric Portrait
Abstract: Dr. Somenath Dutta allies Rahul is a global recognized scientist for his outstanding recent discovery of “miRNA therapeutics for the Zika virus” at the age of 26 years, which can be cured Liver Cancer and allied health problems due to Zika virus disease. This study covers his 12 publications in variety of forms including 07 journal articles (59%), 03 conference papers (25%), 01 dissertation, and 01-chapter paper during 2019-2024. All …
Published in International Journal of Virus Studies · Vol. 2, Issue 2, 2025 · pp. 22–36 Read article
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A Clinical Insight Into Management of Left Sided Hydrocele through Homoeopathy: A Case Report
Abstract: Hydrocele is a common condition in pediatric age groups, characterized by the accumulation of serous fluid within the tunica vaginalis surrounding the testis. While many cases resolve spontaneously within the first one to two years of life, persistent hydrocele beyond this period is generally managed surgically. The present case highlights the role of individualized homoeopathic treatment as a conservative approach in such conditions. A 2-year-old male child presented with left-sided …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 13, Issue 2, 2026 · pp. 1–11 Read article
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Uttarabasti in Female Infertility: A Retrospective Analysis of Clinical Outcomes and Safety Profile
Abstract: Background: Uttarabasti (UB) is a specialized Panchakarma procedure involving intrauterine instillation of medicated Sneha, classically indicated in Yonivyapad and Vandhyatwa. It facilitates targeted local drug delivery, bypassing gastrointestinal metabolism and enabling direct therapeutic action at the uterine level. In Ayurvedic understanding, UB achieves Garbhashaya Shuddhi and Apana Vata Anulomana — the two primary pathological corrections considered essential in Vandhyatwa. Infertility affects an estimated 10–15% of couples globally, with a substantial …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 13, Issue 2, 2026 Read article
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Uttarabasti in Female Infertility: A Retrospective Analysis of Clinical Outcomes and Safety Profile
Abstract: Background: Uttarabasti (UB) is a specialized Panchakarma procedure involving intrauterine instillation of medicated Sneha, classically indicated in Yonivyapad and Vandhyatwa. It facilitates targeted local drug delivery, bypassing gastrointestinal metabolism and enabling direct therapeutic action at the uterine level. In Ayurvedic understanding, UB achieves Garbhashaya Shuddhi and Apana Vata Anulomana — the two primary pathological corrections considered essential in Vandhyatwa. Infertility affects an estimated 10–15% of couples globally, with a substantial …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 13, Issue 2, 2026 · pp. 1–14 Read article
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Descriptive Research Study to Assess the Knowledge of Mental Illness and its Prevention among People Residing in Selected Areas of Shrirampur
Abstract: Introduction: Mental disorder is a syndrome characterized by the clinical significant disturbance in the cognition, emotion regulation or behavior that reflects a dysfunction in the developmental processes underlying mental functioning psychological and biological Method And Material: A descriptive study was carried out to the ‘A study to assess the level knowledge of common people regarding mental illness and its prevention residing at selected areas Data was collected from selected forty …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 11, Issue 1, 2021 · pp. 33–36 Read article
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A Comprehensive review on phytomedicinal activity of chirchita (Achyranthes aspera): an Indian Rural Medicinal Plant
Abstract: Because it is used to treat many types of diseases. Native to India, Achyranthes aspera (Chirchita) has been used in rural medicine for generations.This review explores the phytomedicinal significance of Achyranthes aspera, focusing on its bioactive compounds and the pharmacological activities that support its use in treating various ailments. This plant is a useful tool in traditional and alternative medicine. Because it has anti-inflammatory properties Antioxidants Antibacterial, anticancer and liver …
Published in International Journal of Tropical Medicines · Vol. 2, Issue 1, 2025 · pp. 74–85 Read article
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Drug Screening Using Stem Cell Technology
Abstract: Stem cell technology in drug screening has transformed the research and development sector of pharmaceuticals. Although stem cells imitate their human counterparts in terms of both safety and potential, it is a new paradigm for mimicking diseases of humans and scale measuring for toxicity. These tissues will, therefore, be more predictive of what will happen in humans during clinical situations, compared to conventional cell lines or animal models, since they …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 3, 2025 · pp. 42–51 Read article