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112 articles for “treatment of tumor”
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A Review on Unmasking Merkel Cell Polyomavirus: From Discovery to Cancer Driver
Abstract: Merkel cell polyomavirus (MCPyV) is a small, non-enveloped, circular double-stranded DNA virus belonging to the Polyomaviridae family, first characterized in 2008. Epidemiological data suggest widespread exposure, with seroprevalence rates approaching 80% in adults. While primary infection is typically asymptomatic, rare integration events in Merkel cells can initiate oncogenesis, yielding Merkel cell carcinoma (MCC), a neuroendocrine skin cancer with a five-year survival rate under 60%. This review integrates findings from six …
Published in International Journal of Virus Studies · Vol. 2, Issue 2, 2025 · pp. 6–11 Read article
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Role of Nitric Oxide in Platelets of Breast Carcinoma
Abstract: Breast cancer is a disease of multifactorial origin; it is seen frequently in women of older age, having family history, affluent society, late age of marriage and first childbirth, early menarche, late menopause, and nulliparity. Oxidative stress results when balance between reactive oxygen species (ROS) production and antioxidant defence is lost which result in mutations, sister chromatid exchanges, cytotoxicity, carcinogenesis etc. Clinical, experimental and epidemiological studies suggest that free radicals …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 8, Issue 2, 2019 · pp. 25–29 Read article
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Impact of Training Program on Recent Innovations in Oncology Among Nursing Professionals
Abstract: Introduction: In recent years, there have been significant advancements and trends in the field of oncology treatment in India. This study aimed to evaluate impact of training program on knowledge regarding recent innovations in oncology among nursing professionals. After ethical approval, a pre-experimental, one group pretest- post-test design was used to conduct this research at anursing college of Punjab. Methods: The sample was selected using the total enumerative sampling technique. …
Published in International Journal of Oncological Nursing and Practices · Vol. 3, Issue 1, 2025 · pp. 9–14 Read article
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Navigating the Depths of Cancer Stem Cells: Unraveling Resistance Mechanisms and Emerging Therapeutic Strategies
Abstract: In the past few decades, comprehensive evidence has convincingly established the presence of cancer stem cells (CSCs) as a minor subset within tumors, contributing to an unusually elevated level of cellular diversity within the malignancy. CSCs are functionally identified by their capacity for self-renewal and differentiation, frequently influenced by signals from their surrounding microenvironment. The interconnected transcriptional, post-transcriptional, metabolic, and epigenetic regulatory networks govern the biological characteristics of CSCs. CSCs …
Published in Recent Trends in Infectious Diseases · Vol. 1, Issue 2, 2024 · pp. 14–18 Read article
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Organometallic Osmium Compounds in Cancer Therapy
Abstract: The exploration of organometallic complexes with osmium as potential anticancer agents was indeed an area of ongoing research. These complexes were being investigated for their unique properties and mechanisms of action against cancer cells. However, it’s essential to note that the field of scientific research is dynamic, and new findings may have emerged since then. Organometallic complexes with osmium can be designed to exhibit specific features that make them promising …
Published in International Journal of Advance in Molecular Engineering · Vol. 1, Issue 2, 2023 · pp. 01–25 Read article
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Ewing’s Sarcoma (ES): A Single Centre Retrospective Study
Abstract: The treatment of Ewing’s sarcoma (ES), which is thought to be derived from primitive mesenchymal cells, involves chemotherapy, surgery and radiotherapy. While there is ample data in the world literature showing drastic changes in outcome of this disease, prognosis in Indian patients is largely unknown due to dearth of studies in our setting. The objective of the present study was to study the clinical, pathologic, cytogenetic profile and outcome of …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 2, Issue 2, 2013 · pp. 1–7 Read article
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Anti-Tumour and Anti-Bacterial Activity of Some Ethno-Medicinal Plants
Abstract: Background: Every year, millions of people are diagnosed with cancer, leading to death in a majority of the cases. Because of the high death rate associated with cancer and serious side effects of chemotherapy and radiation therapy, many cancer patients seek alternative methods of treatment. Regarding the safety and effectiveness of natural therapies, the researchers are more interested in the use of natural medicine. In the present investigation, the anti-tumour …
Published in Research and Reviews : A Journal of Immunology · Vol. 7, Issue 3, 2017 · pp. 16–22 Read article
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Management of Compound Odontome: A Case Report
Abstract: Odontomes are developmental anomalies of the dental tissues and may interfere with the eruption of the associated tooth. Since, these lesions are asymptomatic; they are usually detected in routine radiographic investigations. They can be thought of as “tooth hamartomas” with the lesion consisting of various tooth components. Early diagnosis, prompt clinical decision making followed by a proper treatment at the right time, results in a favourable prognosis. The present report …
Published in Research and Reviews: A Journal of Dentistry · Vol. 8, Issue 1, 2017 · pp. 13–16 Read article
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Artificial Intelligence in Medical Fields
Abstract: Artificial intelligence (AI) is a branch of computer science capable of analyzing complex medical data. This can be used in diagnosis, treatment and predicting outcome in many clinical scenarios. Medicine and internet searches were carried out using the keywords ‘artificial intelligence’ and ‘neural networks’. An overview of different AI techniques is presented in this paper along with the review of importance in clinical applications. The proficiency of AI techniques has …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 8, Issue 1, 2019 · pp. 1–3 Read article
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Comparative Study of Machine Learning Algorithms for Detection of Breast Cancer
Abstract: Breast cancer continues to be the most commonly diagnosed cancer among women, with more than 2.3 million new cases diagnosed yearly worldwide. It is stated as the leading cause of cancer-related deaths. Therefore, this emphasizes the dire necessity for early diagnosis with a view to improving survival. Early diagnosis elevates the effectiveness of prediction and treatment. This research carries out a structured and analytical evaluation of various machine learning algorithms, …
Published in Journal of Artificial Intelligence Research & Advances · Vol. 12, Issue 2, 2025 · pp. 113–129 Read article
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Nanomedicine in the Tumor Microenvironment: Physiological Modulation Through Tissue Engineering Approaches
Abstract: The integration of nanomedicine and tissue engineering offers transformative strategies for cancer therapy by directly modulating the physiological processes within the tumor microenvironment (TME). This review emphasizes recent advances in nanomedicine that enable precise drug delivery, controlled release, and real-time monitoring of key physiological parameters influencing tumor progression, angiogenesis, and immune evasion. Tissue-engineered 3D tumor models provide physiologically relevant platforms that better mimic in vivo conditions than traditional 2D cultures, …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 13, Issue 1, 2026 · pp. 19–31 Read article
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Small Cell Neuroendocrine Carcinoma of Cervix: A Case Report and Review
Abstract: Cancer cervix ranks third of all cancers in the world. It remains a leading cause of cancer related death in the developing country. Various histologic subtypes seen in cancer cervix, squamous cell carcinoma (70%) is the most common one. Second common variety observed is adenocarcinoma which account for about 25% of cases. Other histologic subtypes are rare. Small cell neuroendocrine cervical carcinoma (SCNCC) is one of such uncommon variant that …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 5, Issue 2, 2016 · pp. 15–18 Read article
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Comparative Effectiveness of Surgical and Nonsurgical Management for Patients with Single Level Lumbar Disc Herniation in terms of Symptom Severity and Quality of Life
Abstract: Background: Sciatica is one of the most severe forms of low back pain, with a lifetime prevalence of approximately 30 percent. Aim: To assess the short-term and long-term efficacy of surgical and conservative care in the incidence of sciatic symptoms and quality of life in standard clinical settings among patients with lumbar disc herniation. Material and Method: It was a retrospective study conducted at the Medical Trust Hospital, Kochi, India. …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 10, Issue 1, 2020 · pp. 25–29 Read article
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NanoBioAI: Utilizing Python to Investigate Magnetocaloric Effects in Magnetotactic Bacteria and Optimized Conditions for Thermotherapy
Abstract: The study presented in the research work represents a multidisciplinary approach, integrating biology, nanotechnology, and artificial intelligence. It specifically highlights the use of python computational power to investigate magnetocaloric effect (MCE) in magnetotactic bacteria (MTB), a phenomenon yet to be fully understood, characterized by reversible heating and cooling effects induced by magnetic fields. MTB are unique in that they contain embedded magnetic nanoparticles ranging from 10–100 nm in diameters. These …
Published in Journal of Artificial Intelligence Research & Advances · Vol. 11, Issue 2, 2024 · pp. 122–131 Read article
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Advances in Lung Cancer Detection and Diagnosis: An Integrative Approach Using Computational Chemistry, Statistics, Bioinformatics, Artificial Intelligence, and Machine Learning
Abstract: Lung cancer is still one of the most common and lethal cancers globally, accounting for more than a million deaths each year. Prompt detection is important, and imaging techniques like chest X-rays, MRIs, PETs, CTs, and molecular imaging have become important tools. But still, even though all these techniques do not provide an accurate classification of the lesion, they have led to the development of computer-based high-resolution image analysis. Computer …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 13, Issue 2, 2026 Read article
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Revisiting the Role of Mindfulness-based Stress Reduction in the Management of Rheumatoid Arthritis
Abstract: Rheumatoid arthritis (RA) is a type of arthritis characterized by a chronic inflammatory disorder that primarily affects the lining of the synovial joints resulting in progressive disability in the movement of diarthrodial joints and arthralgia. It is a debilitating disease associated with premature death and socioeconomic burdens. Its pathogenesis is multifactorial with an individual course of progression where psychological stress is considered to be one of the risk factors associated …
Published in International Journal of Vaccines · Vol. 1, Issue 1, 2024 · pp. 19–28 Read article
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Role of Radiation Therapy in the Management of Mycosis Fungoides
Abstract: Cutaneous T-cell lymphoma (CTCL) consists of spectrum of diseases of which Mycosis Fungoides and Sézary's syndrome are most common. Mycosis Fungoides (MF) is a low-grade, chronic lymphoproliferative disorder affecting skin caused by abnormal proliferation of CD4 + T-cells. The incidence of MF is showing an increasing trend all over the world. Also, it is seen twice as often in males as in females (2:1) and mostly it occurs after fourth …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 1, Issue 1, 2012 · pp. 6–15 Read article
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Monostotic Fibrous Dysplasia: Facial Swellings A Diagnostic Conundrum
Abstract: Asymmetrical swelling of the mandible in children may pose a significant diagnostic dilemma. The differential diagnosis ranges from traumatic, infectious, and metabolic processes to benign and malignant tumors that may present with similar clinical and radiological features, making an accurate diagnosis quite difficult. This is an illustrative case involving an 11-year-old girl who initially presented with tumefaction of the mandible and after several investigations and referrals were diagnosed as Monostotic …
Published in Research and Reviews: A Journal of Dentistry · Vol. 2, Issue 1-3, 2011 · pp. 45–49 Read article
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Clone-Specific Drug Delivery Systems: Targeted Approaches and Future Clinical Applications
Abstract: Clone-specific drug delivery systems represent a transformative frontier in personalized medicine, addressing the longstanding challenge of clonal heterogeneity within diseases such as cancer, infectious diseases, and autoimmune disorders. Traditional drug delivery platforms often fail to discriminate between pathogenic and healthy cells, leading to systemic toxicity and reduced therapeutic efficacy. In contrast, clone-specific systems aim to selectively target and eliminate disease-driving cellular clones based on unique molecular signatures, thereby improving treatment …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 2, 2025 · pp. 21–29 Read article
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Novel 1,3,4-Thiadiazole Derivatives: Design, Synthesis, Characterization and Anticancer Evaluation – A Review
Abstract: Cancer remains one of the leading causes of mortality worldwide despite significant advances in diagnosis and treatment. The clinical usefulness of many anticancer drugs is often restricted by toxicity, poor selectivity, and the emergence of drug resistance. These limitations have encouraged the search for novel heterocyclic compounds with improved therapeutic efficacy and safety. Among these, the 1,3,4-thiadiazole scaffold has gained considerable attention because of its favorable physicochemical characteristics, metabolic stability, …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 13, Issue 2, 2026 · pp. 42–49 Read article