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150 articles for “immunological”
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Prevalence of HIV Associated Neuro-cognitive Deficit among HIV Positive People in Ethiopia: A Cross Sectional Study at Hawassa University Comprehensive Specialized Hospital
Abstract: Background: HIV/AIDS is a common infection in sub-Saharan Africa which is also associated with neurocognitive impairment and psychological. Even if HAART reduces HIV-associated neurocognitive disorders (HAND) by approximately 60 percentage, over 8 million HIV-infected adults in sub-Saharan Africa will be cognitively impaired at some level. This study aimed to assess prevalence and factors associated with neurocognitive impairment among adults living with HIV/AIDS at Hawassa University comprehensive specialized hospital, Ethiopia. Methods: …
Published in Research and Reviews : A Journal of Immunology · Vol. 8, Issue 3, 2018 · pp. 13–18 Read article
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Asymptomatic Malaria—A Missed Opportunity in the Planned 2030 Malaria Elimination Programme in Ethiopia
Abstract: Background: Malaria intervention in Ethiopia has been strengthened significantly in the past decade with significant reduction in incidence and prevalence. However, continuous surveillance on malaria disease incidence was suggested for effective control and elimination. In difference to this suggestion, malaria elimination programme in the country is missing asymptomatic malaria as a prime target. Thus, the aim of this study was to determine prevalence of asymptomatic malaria and associated factors in …
Published in Research and Reviews : A Journal of Immunology · Vol. 9, Issue 1, 2019 · pp. 4–9 Read article
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Study of Platelet Count in Dengue Fever, Function and Their Importance in Hemostasis
Abstract: Dengue infection is a major vector-borne disease. Compatible hematological discovery comprises of vasculopathy, thrombocytopenia, and coagulopathy. The study comprises of 60 patients and all the cases were studied in the Department of Pathology, Kachchhi laboratory, Amreli, Gujarat, India. In this study, out of 60 cases, there were 12 cases of IgG positive and 31 cases of IgM positive. In which seven males had IgG infection and 18 males had IgM …
Published in Research and Reviews : A Journal of Immunology · Vol. 9, Issue 1, 2019 · pp. 1–3 Read article
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Characterization of a Broadly Specific LPS-Neutralizing Single Domain Antibody
Abstract: Gram negative endotoxaemia or sepsis remains a lethal challenge to humans and animals, globally. Single domain antibodies (dAbs) have emerged as therapeutic biologics for challenging antigens such as lipopolysachharide (LPS). The present study characterized a broadly specific LPS-neutralising dAb produced from phage display library from LPS-immunized Indian desert camel, for its sequence validation with mass spectrometry. Also, the dAb clone 26 was subjected to co-crystallisation with LPS, extracted from E. …
Published in Research and Reviews : A Journal of Immunology · Vol. 7, Issue 1, 2017 · pp. 1–7 Read article
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Factors Influencing the Desire to Have a Baby Among Mothers on ARV Drugs Attending the ART Clinic in Mekelle Hospital
Abstract: Background፡ With the introduction of HAART there has been dramatic reduction in mortality and morbidity, quality of life has been changed and new infections have dropped markedly. Most recently fertility issue in HIV positive men and women are becoming increasingly important. Advance in treatment such as zidovudine and other drugs together with cesarean section and breast milk substitution has decreased vertical transmission to about 2%. This makes parenting a viable …
Published in Research and Reviews : A Journal of Immunology · Vol. 7, Issue 1, 2017 · pp. 9–17 Read article
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Study of Homicide Cases in Barpeta, Assam
Abstract: Homicide means destruction of human life by the act, agency, procurement or culpable omission of some other person(s). Killing of human being is one of the most serious and major crimes. The incidence of homicide is increasing day by day all over the world. Objective of this study was to find out the patterns of homicidal death in Barpeta district of Assam, India. It is observed that 102(9.7%) cases of …
Published in Research and Reviews : A Journal of Immunology · Vol. 7, Issue 1, 2017 · pp. 18–22 Read article
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Patterns of Death Due to Cardiac Injuries in the Barpeta District of Assam
Abstract: Cardiac trauma is a leading cause of death all over the world. It occurs mostly due to motor vehicular accidents. The objectives of this study was to study the demographic pattern of death due to cardiac injuries in Barpeta district of Assam, India, in the year 2014. During this period, a total number of 514 medicolegal autopsies were conducted; of which 188 were trauma-related deaths. Among this, 34 cases had …
Published in Research and Reviews : A Journal of Immunology · Vol. 7, Issue 1, 2017 · pp. 23–27 Read article
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Community Acceptance towards Male Midwives in Tigray, Northern Ethiopia, 2015/16
Abstract: Cognizant to the higher maternal mortality ratio, limited access of maternal health services and scarcity of trained health professionals in developing countries including Ethiopia, unwilling to use the existing health services considering the sex of the healthcare providers poses additional challenge for maternity care. Though remained uncovered, pregnant women’s acceptance towards male midwife becomes more awful for uptake of the services provided by the health system. Hence, the current study …
Published in Research and Reviews : A Journal of Immunology · Vol. 7, Issue 3, 2017 · pp. 28–44 Read article
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Mumps Outbreaks in Vaccinated Population
Abstract: The available approved safe and effective vaccines have prevented millions of deaths. When compared to prevaccine era, more than 98% decrease has been recorded for many diseases like diphtheria, invasive Haemophilus influenzae, measles, rubella, rotavirus, and hepatitis A. Further, the successful global eradication of small pox and near-elimination of polio from most of the global regions underlines the importance of vaccination. The available literature on mumps reveals that it is …
Published in Research and Reviews : A Journal of Immunology · Vol. 4, Issue 2, 2014 · pp. 8–11 Read article
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Magnitude and Risk Factors of Ante-partum Hemorrhage in Lemlem Karl Hospital, Tigray, Northern Ethiopia
Abstract: Antepartum Hemorrhage (APH) is a grave obstetrical emergency. APH continues to be a major cause of maternal and perinatal morbidity and mortality even in modern obstetrics. It is one of the most frequent emergencies. Vaginal bleeding in the third trimester complicates 2–5% of all pregnancies. It is considered an obstetric emergency because hemorrhage remains the most frequent cause of maternal and fetal deaths. It is a critical for the well-being …
Published in Research and Reviews : A Journal of Immunology · Vol. 5, Issue 1, 2015 · pp. 13–22 Read article
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The Response of Blood Platelets to the Vibration Sound in Healthy Subjects and Hypertensive, Diabetic Patients: In Vitro Study
Abstract: Vibration-induced changes in the platelets activity as a result of increased share stress. Mean platelet volume (MPV) is a good indicator of platelet activation. This study aimed to study the effect of vibration sounds, evoked by tuning fork, on the MPV of healthy subjects, hypertensive and diabetic patients in vitro study model. Venous blood samples obtained from healthy subjects (n=7), hypertensive (n=7) and diabetic patients (n=7) were exposed to vibration …
Published in Research and Reviews : A Journal of Immunology · Vol. 5, Issue 1, 2015 · pp. 23–28 Read article
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Vaccine Candidates and Animal Models for Kala-Azar
Abstract: Kala-azar or Visceral Leishmaniasis (VL) is a serious human disease in tropical regions and rapidly emerging as an opportunistic infection in HIV patients. The available treatment against VL is associated with toxicity and drug resistance. Even though the development of vaccines against VL is received limited attention. The only successful immunization strategy in humans has been leishmanization, which is based on the development of durable immunity after recovery from infection …
Published in Research and Reviews : A Journal of Immunology · Vol. 5, Issue 1, 2015 · pp. 29–35 Read article
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Adherence to PMTCT and Its Associated Factors among Women Who Visited Maternity Care Services in Mekelle Public Hospitals in 2014
Abstract: Prevention of mother-to-child HIV transmission (PMTCT) remains a challenge in low- and middle-income countries. Ethiopia is the second most populous country in Africa, next to Nigeria. The country’s poor socioeconomic status, and repeatedly poverty stricken society depends on subsistence farming. The health status has also been explained with high morbidity and mortality and low life expectancy (49 years). Thus, this paper attempts to assess the adherence and its associated factors …
Published in Research and Reviews : A Journal of Immunology · Vol. 5, Issue 2, 2015 · pp. 1–7 Read article
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Aluminum Oxide Nanoparticle-Adjuvanted Pasteurella multocida B:2 Vaccine is Potent and Efficacious and is Able with Keyhole Limpet Hemocyanin as a Marker to Differentiate Infected from Vaccinated Animals (DIVA)
Abstract: Pasteurella multocida B:2 causes hemorrhagic septicemia (HS) in bovines in Asia. For effective implementation of HS control program in India, a safe and efficacious vaccine to provide long lasting protection and allow differentiation of infected from vaccinated animals (DIVA) has to be developed. The objectives of the present study were to develop HS-DIVA vaccine with a companion immunodiagnostic test using keyhole limpet hemocyanin (KLH) as a marker, and to improve …
Published in Research and Reviews : A Journal of Immunology · Vol. 5, Issue 2, 2015 · pp. 8–16 Read article
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Necessity of Multiple Strategies to Combat and Eliminate Rabies
Abstract: Rabies is a vaccine-preventable viral disease and is the deadliest of all human diseases. There is no cure or treatment for disease, but disease is preventable by post-exposure immunization. Rabies is a zoonotic disease and a number of animals are reservoirs. Dogs have historically been associated with rabies transmission to humans, but cats, bats also transmit rabies to humans. Globally, around 55,000 people die of rabies every year. Global estimate …
Published in Research and Reviews : A Journal of Immunology · Vol. 5, Issue 2, 2015 · pp. 17–20 Read article
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Down’s Syndrome (DS): A Genetic Disorder
Abstract: Down’s syndrome (DS) is a chromosomal disorder which occurs due to an error in cell division subsequently leading to an extra 21st chromosome. DS or trisomy 21 is a condition where an individual has 47 chromosomes in each cell instead of 46. It is a multisystem disorder as it affects more than one system of our body. As a consequence, impairments in both cognitive ability and physical growth take place …
Published in Research and Reviews : A Journal of Immunology · Vol. 5, Issue 2, 2015 · pp. 21–26 Read article
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Over Expression of Genes at Long Arm of 21 Chromosome in Case of Down Syndrome
Abstract: Down Syndrome (DS) is a genetic disorder which is caused due to trisomy at chromosome 21 or gene dosage imbalance. DS leads to mental retardation in humans. It is a multisystem disorder as it affects several systems of our body like cardiovascular, respiratory, gastrointestinal, neurological, hematopoietic and musculoskeletal system. The principal cause of DS is unknown yet. Some factors are responsible for DS. like reproduction at advanced maternal age, folic …
Published in Research and Reviews : A Journal of Immunology · Vol. 5, Issue 2, 2015 · pp. 27–34 Read article
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Role of Private Health Sector in Provision of Quality Health Service in Developing Countries: Does the Private Health Sector Contribute to Achieve Health-Related MDGs? A Systematic Review
Abstract: The private health sector may be defined as comprising all healthcare providers who exist outside the public sector, whether their aim is philanthropic or commercial, and whose aim is to treat illness or prevent diseases. The existing potential in the private health sector should be exploited well. Governments in low income countries can apply various strategies to work together with the private sector, such as giving training, applying regulatory and …
Published in Research and Reviews : A Journal of Immunology · Vol. 5, Issue 3, 2015 · pp. 7–13 Read article
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Validation of Child Care Clinic Health Data Reported Under Health Management Information System by the Primary Health Centres of Rural Vadodara, Gujarat
Abstract: Primary child health care is a part of the Maternal and Child Health (MCH). The World Health Organization (WHO) has developed a single, integrated, algorithmic and effective approach for managing childhood illness—the Integrated Management of Childhood Illness (IMNCI)—which can be applied at frontline centers. Therefore, the present study was conducted with the aim to study the child health care data reported by the primary health centre/ subcentre (PHC/SC) and validate …
Published in Research and Reviews : A Journal of Immunology · Vol. 5, Issue 3, 2015 · pp. 14–22 Read article
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Partograph: An Essential Tool for Midwives to Manage Labor at Public Health Institutions in Tigray, Northern Ethiopia
Abstract: A partograph is a graphical presentation of a woman’s progress of labour. Once the woman has true signs of labour and reaches active first stage of labor, the midwife initiates the use of the partograph to record her findings. Prolonged labor; mainly due to cephalopelvic disproportion (CPD), which may result in obstructed labor, maternal dehydration, ruptured uterus, obstetric fistulae, fetal asphyxia, fetal brain damage, infection and death of both mother …
Published in Research and Reviews : A Journal of Immunology · Vol. 5, Issue 3, 2015 · pp. 23–29 Read article