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89 articles for “Depression”
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Mental Health in the Post-Pandemic Era (COVID-19): Community-Based Interventions for Resilience and Well-Being
Abstract: Background: The COVID-19 pandemic has had a major psychological effect, causing anxiety, depression, stress, and social disruption around the world. Community-level mental health programs have become widely available methods for promoting resilience and mental well-being, especially in resource-limited contexts. Aim: The aim was to assess the effectiveness of community-based mental health interventions in promoting psychological resilience and overall well-being in the post-pandemic period. Methodology: A cross-sectional, mixed-method, community-based study was …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 15, Issue 1, 2026 Read article
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Childhood Obesity: From Determinants to Clinical Management strategies
Abstract: Childhood obesity is one of the major global health problems in whole world, with a dramatic increase in prevalence over the recent few decades. Obesity associated with very serious long term health complications and sometimes very serious complications, such as metabolic disorders, cardiovascular, neurological, renal and psychological disorders. There are various factors such as genetic, environmental, behavioural, and socio-economic factors are some key player in the pathogenesis of obesity. In …
Published in Research and Reviews: A Journal of Health Professions · Vol. 16, Issue 1, 2026 · pp. 45–53 Read article
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The Renaissance and Resilience of CB1 Reverse Agonists: From Central Liabilities to Peripheral Promise
Abstract: Building upon these foundational insights, current research has increasingly focused on refining the pharmacological profile of CB1 reverse agonists to maximize therapeutic benefit while minimizing central adverse effects. The adverse neuropsychiatric outcomes associated with first-generation agents such as Rimonabant including anxiety, depression, and suicidal ideation highlighted the critical role of central CB1 receptors in mood regulation. Consequently, drug development strategies have shifted toward peripherally restricted CB1 reverse agonists that exhibit …
Published in International Journal of Cheminformatics · Vol. 4, Issue 1, 2026 · pp. 30–35 Read article
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Molecular Dynamics and Therapeutic Architectures of Cannabinoid Receptors: A Comprehensive Review
Abstract: Expanding on these foundations, recent structural biology studies using cryo-electron microscopy have provided high-resolution insights into the conformational dynamics of CB₁ and CB₂ receptors. These findings have enabled a more precise understanding of ligand–receptor interactions, particularly how agonists, antagonists, and reverse agonists stabilize distinct receptor states. Such knowledge is critical for rational drug design, allowing researchers to selectively modulate downstream signaling pathways. For instance, CB₁ receptors primarily couple to Gi/o …
Published in International Journal of Cheminformatics · Vol. 4, Issue 1, 2026 · pp. 36–40 Read article
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Association Between Smartphone Addiction and Functional Exercise Capacity in College Students
Abstract: Smartphone addiction has become increasingly prevalent among college students and is associated with various negative physical and psychological outcomes. Functional exercise capacity, a key indicator of physical fitness and health, may be adversely affected by excessive smartphone use due to sedentary behavior and reduced physical activity. This article examines the association between smartphone addiction and functional exercise capacity in college students by analysing behavioral, psychological, physiological, and methodological perspectives. Evidence …
Published in International Journal of Orthopedic Nursing and Practices · Vol. 4, Issue 1, 2026 Read article
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A Lightweight Cost-Sensitive Explainable Ensemble Framework for Early Heart Disease Risk Prediction
Abstract: Cardiovascular disease is still one of the leading causes of death, and hence, the early prediction of risk is a very important task in preventive medicine. Although recent studies have shown encouraging results in the application of machine learning algorithms to the prediction of heart disease, it has been noticed that most of the algorithms are more concerned with accuracy-driven optimization than the concerns of safety and false negatives. In …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 4, Issue 2, 2026 Read article
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Real-Time Browser-Based Early Warning System for Cyberbullying Detection in Online Platforms
Abstract: The rise in social networking through internet-based communication tools, Instagram, and YouTube, to name a few, significantly increases the risk of cyberbullying, thereby increasing psychological trauma on users, especially children, through adverse emotional states like anxiety, depression, etc. For a long time, researchers have been enhancing detection tools to counter cyberbullying, but their ability to detect only after the fact, along with limited support for English-based architecture, is a major …
Published in International Journal of Computer Science Languages · Vol. 4, Issue 1, 2026 · pp. 09–15 Read article
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Interrelationship Between Psychological Stress and Gastrointestinal Physiology: Role of the Gut–Brain Axis
Abstract: The relationship between stress and gut microbiome is a critical area of medical research underscoring the relativity and impact of psychological and emotional states on gastrointestinal (GI) health. This paper investigates the intricate relationship between stress and digestive health by analysing the influence of stress hormones, gut–brain interactions, and psychosocial determinants. Both acute and long-standing stress responses may disrupt normal gastrointestinal activity, affecting motility, secretion, intestinal microbiota, and overall digestive …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 15, Issue 2, 2026 Read article
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An Analytical Study of the Effectiveness of the Child Development Scheme in Anganwadi Centers of Rudraprayag District
Abstract: From the perspective of human development, childhood is regarded as a highly sensitive and multidimensional phase that plays a pivotal role in shaping the trajectory of human life. During childhood, children undergo rapid growth across their mental, social, psychological, and physical domains. Currently, the mental, physical, and social well-being—as well as the overall health—of children remains a grave challenge for the entire world. An increase in nutritional and health-related problems …
Published in International Journal of Children · Vol. 3, Issue 2, 2026 · pp. 35–47 Read article