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109 articles for “Candidate gene”
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Record Linkage in Knowledge Discovery Process Using Angle Based Machine Learning
Abstract: Record linkage is a critical data cleansing step in the knowledge discovery process, aimed at identifying and resolving inconsistencies across datasets. This study proposes an enhanced record linkage framework tailored for uncertain and large-scale data using a combination of distance measurement, probabilistic modeling, and semantic reasoning. A novel angle-based distance measurement technique is introduced to optimize matching between candidate records. To further boost match accuracy, a Finite Mixture Model (FMM) …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 1157–1170 Read article
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Exploring The Therapeutical Potential Of Pongamia Pinnata For Herpes Simplex Virus Type 1 (HSV-1)
Abstract: Objective: Pongamia pinnata (L.), commonly known as Indian beech or pongam tree, is a tropical plant renowned for its medicinal properties in traditional medicine systems. Extracts derived from various parts of Pongamia pinnata have demonstrated antimicrobial, anti-inflammatory, and immunomodulatory activities. Such attributes make it a compelling candidate for exploring its therapeutic potential against HSV infections. Thymidine kinase is the target protein mostly used in the treatment of HSV1 infections. In …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 15, Issue 1, 2025 · pp. 1–9 Read article
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String Theory: Simplified Insights into Reality
Abstract: "String Theory: Simplified Insights into Reality" explores the fascinating realm of theoretical physics, delving into the profound principles of string theory and its implications for our understanding of the fundamental nature of the universe. The paper begins with an overview of the historical context, tracing the evolution of string theory from its inception as a theoretical framework to its current status as a leading candidate for a unified theory of …
Published in Research & Reviews : Journal of Space Science & Technology · Vol. 13, Issue 1, 2024 · pp. 1–11 Read article
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RCCI Engine: Performance and Emission Testing Using Biodiesel
Abstract: With dwindling fossil fuel reserves and rising energy demands, the need for renewable alternatives is more critical than ever. This study explores the potential of Karanja biodiesel, a fuel derived from Karanja oil, as a sustainable replacement for diesel in RCCI engines. Karanja biodiesel offers several advantages. It's renewable, reduces dependence on fossil fuels, and produces lower emissions compared to traditional diesel. This research investigates how Karanja biodiesel blends impact …
Published in Journal of Energy, Environment & Carbon Credits · Vol. 13, Issue 3, 2023 · pp. 30–41 Read article
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Machine Learning Using Python
Abstract: Machine learning (ML) is a subset of artificial intelligence (AI) that enables software applications to become more accurate at predicting outcomes without explicitly programming them to do so. Machine learning algorithms predict new output values by using historical data as input. In this project, we have used data from the 1994 U.S. Census to model people's income using numerous supervised algorithms of your choice. The best candidate algorithm will then …
Published in Recent Trends in Programming languages · Vol. 8, Issue 3, 2021 · pp. 25–37 Read article
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Autonomous Agentic AI for Adaptive Cure Optimization and Defect Prevention in Thermoset Polymer Composite Manufacturing
Abstract: Thermoset polymer composites occupy a central position in modern structural manufacturing, from aircraft fuselages to wind-turbine blades. Despite progress in resin chemistry and fiber architecture, the “cure process” that transforms compliant preforms into load-bearing structures remains difficult to manage. Manufacturers encounter ‘voids’, “interlaminar delaminations”, and “spring-back distortion” when curing complex or thick-section parts. The cause is not ignorance of the relevant physics, but rather that ‘temperature’, ‘chemistry’, ‘rheology’, and ‘mechanics’ …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 301–320 Read article
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On the Interplay between Surface Roughness and Cell Thickness for Efficient CZTS Thin Film Solar Cells
Abstract: Today's thin-film photovoltaic technologies comprising CuInS2 (CIS), CuInGaSe2 (CIGS) and CdTe elements that are costly and rare and in the earth crust such as In, Ga, Te and toxic like Cd. Henceforth, in future, expense decrease, proficient and expanded creation, utilizing bounteously accessible nonharmful components, appear to be the fundamental issue to deliver large scale manufacturing and effective sunlight-based cells. Cu2ZnSnS4 (CZTS), having the kesterite structure, is perhaps the most …
Published in Journal of Nanoscience, NanoEngineering & Applications · Vol. 11, Issue 1, 2021 · pp. 16–24 Read article
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Formulation and Evaluation of an Antifungal Emulgel Containing Carbopol 940 as Gelling Agent
Abstract: Emulgels have emerged as one of the most intriguing topical distribution systems as they have dual release control system, i.e., gel and emulsion. The main purport of the present study was to develop and evaluate topical emulgel system for Fluconazole, antifungal agent, utilizing different polymers namely carbopol 940. In addition, light liquid paraffin as oil, Tween-20 and Span-20 as emulsifiers and propylene glycol and methyl alcohol as co-surfactant were culled …
Published in Trends in Drug Delivery · Vol. 2, Issue 1, 2015 · pp. 28–37 Read article
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Allelopathic Nature of Cucumis Prophetarum Linn.
Abstract: ABSTRACTCucumis prophetarum Linn. is perennial, monoecious climber, commonly growing weed, belonging to family Cucurbitaceae. The whole plant of C. prophetarum is medicinally important. Plant pacifies vitiated dysentery, diarrheic diseases, flatulene, skin diseases, antivenin and general debility. Dispending medicinally uses, our study has found that this weed is allelopathic in nature. To check the allelopathic activity, C. prophetarum was assessed for the effects of their extracts on the growth of mature …
Published in Research & Reviews : Journal of Botany · Vol. 1, Issue 1, 2012 · pp. 16–21 Read article
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Machine Learning Approaches Towards Resume Classification
Abstract: Finding the right person for an open position can be an unnerving task, especially when there are many applicants, and if the recruiter or the Human Resources department must sort and further categorize all those resumes then it will be a labor-intensive, time-consuming, and tiresome task. Additionally, human assessment of resumes may be biased and prone to mistakes. Manually screening the proper candidate's resume from the pool is not practicable; …
Published in International Journal of Electronics Automation · Vol. 1, Issue 2, 2023 · pp. 1–7 Read article
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Alternate Web Query Generation and Refined Search Results Using Query Expansion
Abstract: AbstractThe sole objective of an information retrieval (IR) task is to facilitate the user’s requests and filter the information which the user has actually intended. Therefore, the principle task of an IR system is to understand the user’s inability and act on behalf of the user’s point of view because most of the web users are novice, unaware of the topic pertaining in the selected domains etc. There has been …
Published in Journal of Computer Technology & Applications · Vol. 6, Issue 1, 2015 · pp. 1–8 Read article
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Regional Variation in Amino Acid Composition, Antioxidant and Antimicrobial Activity of Tasar Sericin from North and South Bihar
Abstract: This study investigates geographical differences in biochemical and functional characteristics of sericin obtained from Antheraea mylitta cocoons sourced from two regions of Bihar, India: Bhagalpur (North) and Banka (South). Sericin was isolated via an alkali-assisted autoclaving process. Amino acid profiles were determined using HPLC. Free radical scavenging capacity was measured through DPPH, ABTS, and hydrogen peroxide assays. Antibacterial and antifungal effects were tested against Staphylococcus aureus, Escherichia coli, and Candida …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 16, Issue 2, 2026 Read article
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Regional Variation in Amino Acid Composition, Antioxidant and Antimicrobial Activity of Tasar Sericin from North and South Bihar
Abstract: This study investigates geographical differences in biochemical and functional characteristics of sericin obtained from Antheraea mylitta cocoons sourced from two regions of Bihar, India: Bhagalpur (North) and Banka (South). Sericin was isolated via an alkali-assisted autoclaving process. Amino acid profiles were determined using HPLC. Free radical scavenging capacity was measured through DPPH, ABTS, and hydrogen peroxide assays. Antibacterial and antifungal effects were tested against Staphylococcus aureus, Escherichia coli, and Candida …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 16, Issue 2, 2026 · pp. 1–10 Read article
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Methodologies for in silico and in vitro Test of Biphenylalanine Compounds as Potential HIV-1 gp120 Attachment Inhibitors
Abstract: We postulate that biphenylalanine and its derivatives are propitious candidates to inhibit the binding of HIV-gp120 to CD4 T-cell. Many biphenylalanine derivatives are synthesized chemically and also prevailing in nature. We have proposed atom- and bond-based 2D TOMOCOMD-CARDD approach to identify the best derivative. Moreover, according to our proposition, the principal law simulated from in silico interaction of gp120 with CD4 can be tested by ELISA in vitro. Furthermore, the …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 2, Issue 3, 2015 · pp. 38–42 Read article
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Advances in Polymer Chemistry for Biomedical Applications: Innovations in Composite Materials
Abstract: Polymer chemistry has seen remarkable progress in recent years, particularly in the biomedical field, where novel polymeric materials are transforming the development of medical devices. These advancements have led to the creation of biocompatible, durable, and multifunctional polymer-based solutions that enhance patient care, surgical precision, and treatment outcomes. The application of polymer chemistry in biomedical sciences has revolutionized medical device manufacturing. Polymers offer unique advantages such as flexibility, biocompatibility, and …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 · pp. 287–292 Read article
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Computational Identification of Protein Tyrosine Phospatase-1B (PTP-1B) Inhibitors for Checking Type II Diabetes
Abstract: Protein tyrosine phosphatases (PTPs) are a family of enzyme that comprises of about 100 proteins which catalyze dephosphorylation of phosphotyrosine residues in protein substrates. Phosphotyrosine is a central element in cell signaling, and its activity is essential for cellular homeostasis and for appropriate responses to extracellular signals. PTP-1B antagonizes insulin signaling by reducing the activation state of the insulin receptor kinase, thereby inhibiting post-receptor signaling in insulin responsive tissue. The …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 6, Issue 3, 2017 · pp. 21–25 Read article
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Polysaccharide-Based Composite Materials for Hemostatic Applications in Trauma Care
Abstract: Uncontrolled hemorrhage remains one of the leading causes of preventable trauma-related mortality worldwide, highlighting the urgent need for rapid, effective, and biocompatible hemostatic materials. Polysaccharide-based composite biomaterials have emerged as promising candidates owing to their excellent biocompatibility, biodegradability, and intrinsic hemostatic properties. Natural polysaccharides, including chitosan, alginate, cellulose derivatives, starch, and hyaluronic acid, are increasingly combined with synthetic polymers, bioactive ceramics, metallic nanoparticles, and other functional additives to enhance mechanical …
Published in Journal of Polymer & Composites · Vol. 14, Issue 5, 2026 Read article
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Synthesis and Evaluation of New Coumarin Derivatives for Inflammatory Bowel Disease Against DSS-Induced Acute Ulcerative Colitis Mice Model
Abstract: Objective: The discovery of the now numerous mouse models of intestinal inflammation has increased our understanding of the intestinal inflammation that occurs in inflammatory bowel disorders (IBD). This study aimed to investigate the use of a standardized animal model subjected to coumarin derivative treatment, and the action of synthesized molecule administration of dextran sodium sulphate (DSS)- induced colitis in experimental mice. Materials and Methods: We generated a variety of unique …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 14, Issue 4, 2023 Read article
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An Empirical Analysis of Bluetooth Low Energy Reliability Challenges for Offline Messaging Applications
Abstract: In today's hyper-connected world, modern communication relies heavily on centralised internet infrastructure, making robust offline messaging solutions increasingly essential. A crucial vulnerability is revealed by network failures, natural disasters, and distant region deployments: communication breaks down when internet connectivity does. Due to its low power consumption and almost ubiquitous availability in contemporary smartphones, Bluetooth Low Energy (BLE) has become a promising candidate for offline, device-to-device communications. This study presents an …
Published in Journal of Mobile Computing, Communications & Mobile Networks · Vol. 13, Issue 2, 2026 Read article
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A Comprehensive review on phytomedicinal activity of chirchita (Achyranthes aspera): an Indian Rural Medicinal Plant
Abstract: Because it is used to treat many types of diseases. Native to India, Achyranthes aspera (Chirchita) has been used in rural medicine for generations.This review explores the phytomedicinal significance of Achyranthes aspera, focusing on its bioactive compounds and the pharmacological activities that support its use in treating various ailments. This plant is a useful tool in traditional and alternative medicine. Because it has anti-inflammatory properties Antioxidants Antibacterial, anticancer and liver …
Published in International Journal of Tropical Medicines · Vol. 2, Issue 1, 2025 · pp. 74–85 Read article