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1049 articles for “Multiplication”
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Anti-inflammatory Potentials of Various Oxine Compound Series as Cyclooxygenase-2 (COX-2) and Lipoxygenase (LOX) Inhibitors: Induced-Fit Molecular Docking and Pharmacokinetic Prediction Studies
Abstract: The present investigation is an exploration of multiple oxine series in inhibiting crucial anti-inflammatory targets such as cyclooxygenase-2 (COX-2) (PDB ID: 3LN1) and lipoxygenase (LOX) (PDB ID: 1N8Q) by employing the Glide module of Maestro 9.1 software for induced fit docking (IFD). The study also focuses in exploration towards the essential pharmacokinetic parameters (QPlogPo/w, QPlogS, predicted aqueous solubility, QPPCaco, QPPMDCK, and percentage of human oral absorption). The study highlighted the …
Published in Research and Reviews : Journal of Computational Biology · Vol. 7, Issue 3, 2018 · pp. 16–23 Read article
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Square Shape CPW Antenna for Breast Cancer Detection
Abstract: In this study, a antenna design is proposed to detect the breast cancer tissues by using microwave imaging based on the contrast in electrical properties of healthy fatty Breast tissues. The designed antenna is affordable as a primary health observation and has no health risk. A highly directive flexible structure is presented for microwave imaging which can be used in clinical diagnosis. To detect the tumour in a breast phantom, …
Published in Research and Reviews : Journal of Computational Biology · Vol. 8, Issue 1, 2019 · pp. 34–38 Read article
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Development of vaccine against Helicobacter pylori using Bioinformatics approaches
Abstract: Helicobacter pylori (H. pylori) are a widespread kind of bacteria which flourish in the digestive tract and have a propensity to damage the stomach lining. The microbe infects around 60% of the adults globally. H. pylori infections are responsible for most of stomach and small intestine ulcers. Using Bioinformatics approaches, we have identified certain proteins that possess the resistance, essentiality and virulence factors for this pathogen. Computational tools and servers …
Published in Research and Reviews : Journal of Computational Biology · Vol. 8, Issue 3, 2019 · pp. 34–68 Read article
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In Silico Molecular Docking Studies of Phytoconstituents Identified in Curcuma zedoaria Rosc. on Acetylcholinesterase: An Enzyme Target for Anti Alzheimer’s Activity
Abstract: Alzheimer’s disease (AD) is a chronic, progressive and disabling organic brain disorder characterized by disturbances of multiple cortical functions. Acetylcholinesterase (AChE) inhibition is thought to be a promising approach towards the treatment of AD. The aim and objective of the present study is to perform in-silico docking analysis of the major active constituents identified in Curcuma zedoaria Rosc. against AChE for anti-Alzheimer’s activity. In this perspective, phytoconstituents like bisdemethoxy curcumin, …
Published in Research and Reviews : Journal of Computational Biology · Vol. 8, Issue 3, 2019 · pp. 9–14 Read article
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The use of Genetics and Proteomics in the Finding of Therapeutic Targets
Abstract: Gene medicine is overcoming long-standing health issues that have confounded humanity. To fully comprehend and apply gene medicine, it is vital to grasp how it works at the molecular level. Currently, various technologies may be utilized to find pharmacological targets; the two most prominent are genomic and proteomic methods. In this paper, we go over how to use genomic and proteomic approaches to find pharmacological targets in depth. These materials …
Published in Research and Reviews : Journal of Computational Biology · Vol. 11, Issue 1, 2022 · pp. 9–12 Read article
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In Silico Drug Designing of Breast Cancer in Homo sapiens
Abstract: Breast cancer is a severe health concern in India, with the highest mortality rate among women. It is brought on by uncontrolled cell division and has the potential to spread to other body regions. As a transcription factor, interactions with estrogen receptor (ER) alpha are primarily responsible for malignant tumors through regulating the transcription of numerous genes. Because most of the medications now used to treat breast cancer have significant …
Published in Research and Reviews : Journal of Computational Biology · Vol. 11, Issue 2, 2022 · pp. 12–27 Read article
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Revolutionizing Cancer Diagnosis: Unleashing the Tab Transformer's Power for Accurate Classification
Abstract: Gene expression platforms offer vast amounts of data that can be utilized for investigating diverse biological processes. However, the presence of redundant and irrelevant genes makes it challenging to identify crucial genes from high-dimensional biological data. To overcome this obstacle, researchers have introduced different feature selection (FS) methods. Developing more efficient and accurate feature selection techniques is essential for selecting important genes in complex biological information with multiple dimensions. In …
Published in Research and Reviews : Journal of Computational Biology · Vol. 12, Issue 2, 2023 · pp. 24–38 Read article
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Alveolar Cysts in a Newborn Infant: A Case Report
Abstract: Cystic lesions of transient nature through Epstein pearls, Bohn’s nodules and dental lamina cysts are frequently found in the oral cavities of newborn infants. These cysts arise from the developing dental tissues or from their remnants. Alveolar cyst is also known as gingival cyst of newborn or dental lamina cyst. This cyst presents as a benign oral lesion which is whitish-yellow in color present on the alveolar ridge of newborns …
Published in Research and Reviews: A Journal of Dentistry · Vol. 8, Issue 3, 2017 · pp. 26–28 Read article
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Dental Considerations in Obstructive Sleep Apnea (OSA): A Literature Review
Abstract: Sleep disorders are becoming a common medical problem. Multiple treatment options have been advocated including the use of dental devices. Dental practitioners becoming a part of the treatment team is again a problem because of the wide variety of dental devices available and the rapid advancement in the understanding of the disease. This article reviews the anatomy, physiology, etiopathogenesis of obstructive sleep apnea (OSA) and various medical and dental treatment …
Published in Research and Reviews: A Journal of Dentistry · Vol. 3, Issue 2, 2012 · pp. 8–14 Read article
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Maxillary Advancement by Distraction Osteogenesis in Maxillary Hypoplasia
Abstract: Cleft lip and palate patients (CLP) are borne with a challenging deformity that requires multiple surgical interventions in order to reach functional and esthetic harmony. Distraction osteogenesis has become a widely used treatment of maxillary hypoplasia in CLP-patients because of the reports of better stability and the possibility for larger advancements. We report our treatment experience with a 19 year old cleft lip and palate female patient, presented with maxillary …
Published in Research and Reviews: A Journal of Dentistry · Vol. 6, Issue 1, 2015 · pp. 18–22 Read article
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Management of Basal Cell Adenoma of Parotid Gland with Blair's Incision
Abstract: A basal cell adenoma (BCA) of salivary gland origin is a rare tumour which was included as a separate salivary gland tumour in the classification schemes by the World Health Organization (WHO) in 1991. It is an uncommon benign salivary gland epithelial tumor which accounts for 1–2% of all salivary gland epithelial tumors and more than 80% of BCAs arises in the major salivary glands, mostly the parotid gland. It …
Published in Research and Reviews: A Journal of Dentistry · Vol. 8, Issue 1, 2017 · pp. 9–12 Read article
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Malocclusions and Associated Factors among Children with Neuropsychological, Sensory and Physical Disabilities in Dar es Salaam, Tanzania
Abstract: Background: Malocclusions have negative impacts on oral health of children with disabilities. Knowledge on factors associated with malocclusions may help planning preventive measures, necessary for disabled children. The study objective was therefore to determine the prevalence of malocclusions and their associated factors among children with disabilities in Dar es Salaam, Tanzania.Methods: It was a cross-sectional survey that involved 384 children with neuropsychological, sensory and physical disabilities in Dar es Salaam, …
Published in Research and Reviews: A Journal of Dentistry · Vol. 8, Issue 1, 2017 · pp. 17–26 Read article
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Current scientific evidence for enhancing the success of root coverage procedures: A step by step guide
Abstract: Background: Gingival recession defects for long have been treated using various root coverage procedures. As the expectations and patient's perception is becoming increasingly more demanding, it has become difficult to achieve patient centered outcomes. A review of scientific literature has been employed and the evidence implies that the success of treatment is dependent on multiple factors.Objectives: The paper aims at providing an evidence based information to clinicians in management of …
Published in Research and Reviews: A Journal of Dentistry · Vol. 12, Issue 1, 2021 · pp. 13–18 Read article
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Knowledge and awareness regarding primary teeth and their importance amongst postgraduate students of specialty other than pediatric dentistry in and around Vadodara city, India – A questionnaire survey
Abstract: AbstractPrimary teeth play an inevitable role in eating, phonetics, esthetics and also act as a spacemaintainer for permanent teeth. Therefore, their retention with a timely checkup and proper intervention due to caries is required till eruption of permanent teeth. This is to prevent the early tooth loss due to caries which is more frequent scenario. This is due to unawareness, ignorance and negligence amongst parents about children’s oral hygiene resulting …
Published in Research and Reviews: A Journal of Dentistry · Vol. 13, Issue 3, 2022 · pp. 22–29 Read article
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Lobulated Tongue- A Rare Devlopmental Anomaly
Abstract: Lobulated tongue is a relatively uncommon congenital anomaly characterized by one or multiple elevations and/or indentations on the edge or surface of the tongue, resulting in an irregular contour. This condition is considered a rare occurrence in the spectrum of human congenital anomalies, and it may present as an isolated case or be associated with syndromes, co-existing with hamartomas or teratomas.Various syndromes have been identified in association with lobulated tongue, …
Published in Research and Reviews: A Journal of Dentistry · Vol. 14, Issue 3, 2023 · pp. 31–34 Read article
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Anticipated Root Coverage Utilizing the Minimally Invasive VISTA Technique with and without Autologous L-PRF: Documentation of Two Case Studies
Abstract: Gingival recession refers to the downward movement of the marginal gingiva from its typical location on the tooth crown to levels along the root surface beyond the cemento-enamel junction. Miller Class I and Class II recession are those for which the prognosis and chances of clinical success is greatest, and numerous evidences in the existing literature reports that the Coronally Advanced Flap (CAF) based procedure along with autologous subepithelial connective …
Published in Research and Reviews: A Journal of Dentistry · Vol. 14, Issue 3, 2023 · pp. 24–30 Read article
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The Effectiveness of Structured Teaching Programme on Role of Iodine in Prevention of Iodine Deficiency Disorders among Women in Selected Urban Areas of Tirupati
Abstract: Background of the Study: Iodine deficiency disorders are emerging as a public health problem, especially in pregnant and breastfeeding women, in whom it can cause brain damage in the developing fetus or infant. Iodine deficiency gives rise to goiter (so called endemic goiter) in adults as well as cretinism in children, which results in developmental delay and other health problems. According to WHO, nearly 2 billion individuals had insufficient iodine …
Published in Research and Reviews: A Journal of Health Professions · Vol. 8, Issue 1, 2018 · pp. 29–38 Read article
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Workplace Violence against Women (WPVAW): The Experience among Healthcare Providers in Nigeria
Abstract: Background: Across the world today, the workplace just like any other public space a woman could find herself has become a place where the woman folk get abused by all categories of people they come in contact with, be it colleagues, service consumers, their relations amongst others.Aim: The study was aimed at assessing the prevalence of workplace violence against women, severity and perpetrators of abuse among healthcare providers in the …
Published in Research and Reviews: A Journal of Health Professions · Vol. 8, Issue 1, 2018 · pp. 42–46 Read article
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Screening of Obesity and its Associated Biochemical Markers in North Indian Population
Abstract: The aim of the present study was to explore out the prevalence of biochemical markers, and their connection with obesity in north Indian population. The sample size was 300, between the ages of 10 and 60 years old from all the ethics of north India. The obesity was calculated by body mass index based on the World Health Organization standard. We collected venous blood for biochemical markers investigation (total cholesterol, …
Published in Research and Reviews: A Journal of Health Professions · Vol. 8, Issue 3, 2018 · pp. 51–54 Read article
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Issues of Indian Rural Women with Disability in Assessing Health Care Services: Social Work Perspective
Abstract: This study focuses on rural women with disability, who are facing issues in the society with reference to education, health, livelihood, social inclusion and empowerment. The study was conducted in drought prone area were the above problems become multiple, Ashirwad Trust for the disabled provides CBR (Community-based rehabilitation) training to disabled person. WHO CBR (Community-based rehabilitation) matrix was modified for assessing education, health, livelihood, social inclusion and empowerment of the …
Published in Research and Reviews: A Journal of Health Professions · Vol. 8, Issue 3, 2018 · pp. 53s–56s Read article