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1974 articles for “investigations” (ranking capped at the first 2,000 matches — narrow the search to see the rest)
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An Integrated Study to Extrapolate the Interaction of NMDAR with Potential Ligands for the Treatment of Alzheimer’s Disease Symptoms
Abstract: Objective: Alzheimer’s disease (AD) is the most common neurodegenerative disease affecting the health status of older adults especially those above the age of 60 years. As an outcome, two types of medications have been developed for the treatment of its symptoms which are acetylcholinesterase (AChE) and N-methyl-D-aspartate receptor (NMDAR) antagonist. This paper uses the computational approach to understand the interaction of NMDAR with four major phytocompounds (curcumin, L-epicatechin, ginsenosides, and …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 1, Issue 1, 2023 · pp. 15–27 Read article
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Anti Covid-19 Drugs Suggested by Computational Methods: A Review
Abstract: Background and aims: Long COVID refers to the persistence of illness in individuals who have survived from COVID-19 infection. This article reviews long covid and the use of in silico techniques in drug development for COVID-19. Results: Many COVID-19 survivors have long COVID, which has become a burden in daily life. Various attempts have been undertaken to relieve symptoms and manage it, but there is no cure as of yet. …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 1, Issue 1, 2023 · pp. 16–34 Read article
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Review Descriptive Programme on Knowledge Regarding Diabetes Mellitus
Abstract: Context: A research study was conducted to assess the knowledge and prevalence of diabetes mellitus among elderly individuals in selected areas of Jalandhar, Punjab. The study also aimed to develop an informative guide sheet. Objectives: (1) To assess the level of understanding about diabetes mellitus among elderly individuals in the selected regions. (2) To determine the prevalence rate of diabetes mellitus among elderly individuals in the selected areas. (3) To …
Published in International Journal of Community Health Nursing And Practices · Vol. 1, Issue 2, 2023 Read article
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Evaluation of Coping Strategies Adapted to Overcome Psychosocial Problems in Adults Residing at Residential Home: A Descriptive Study
Abstract: Coping strategies refer to intentional actions taken to address and resolve personal or interpersonal challenges, aiming to manage, reduce, or tolerate stress or conflicts. Emotional-focused techniques specifically target the reduction of negative emotional responses caused by stressors. Some examples of coping strategies focused on emotions involve participating in activities to keep oneself busy and divert attention from stressors, seeking support, encouragement, empathy, and understanding from others. Objectives: (1) to assess …
Published in International Journal of Community Health Nursing And Practices · Vol. 1, Issue 1, 2023 Read article
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Flow Structures Around Proposed Bridge Piers
Abstract: The current study investigated the flow hydrodynamics around proposed bridge pier and made comparison with existing bridge pier. To quantify the flow structures around the piers, the flow and turbulence parameters are analysed to understand the interference of one bridge pier over another. The experiments were performed on recirculating channel of 15 m length, 0.89 m width and 0.65 m height. Instantaneous three-dimensional velocity data was recorded by acoustic Doppler …
Published in Journal of Polymer & Composites · Vol. 11, Issue 1, 2023 · pp. 14–21 Read article
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Effect of Formaldehyde Treatment on the Barrier and Mechanical Properties of Oat Protein Films
Abstract: Oat protein 5% with 40% glycerol as a plasticizer was used to prepare edible films, and formaldehyde was chemically added to the film's solution at four concentrations. The films' barrier and mechanical properties were then investigated. The films were characterized by being medium transparency, homogeneous, odorless, and with a thickness ranging between 0.12 and 0.15 mm. It was also observed that the water vapor permeability decreased whenever the concentration of …
Published in Journal of Polymer & Composites · Vol. 11, Issue 2, 2023 · pp. 1–8 Read article
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Pharmacological Management of Parkinson’s Disease: Current Therapies and Emerging Treatments
Abstract: Objective: Parkinson's disease, behind Alzheimer's, is the second most common neurodegenerative ailment and a major cause of neurological morbidity worldwide. Clinical diagnosis is made, and current management is limited to symptomatic treatments, with levodopa remaining the cornerstone of pharmaceutical therapy. In certain patient groups, deep brain stimulation of specific basal ganglia targets can provide significant clinical relief. There are currently no proven disease-modifying medicines in clinical use that can halt …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 1, Issue 1, 2023 · pp. 27–39 Read article
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A Critical Study of Research Challenges for Self-adaptive Software
Abstract: Software systems dealing with distributed applications in changing environments normally require human supervision to proceed with activity in all conditions. These rearranging, investigating, and all in all upkeep errands prompt exorbitant and tedious strategies amid the working stage. These issues are principally because of the open-circle structure regularly followed in programming advancement. Hence, there is popularity for administration many-sided quality decrease, administration mechanization, vigor, and accomplishing the majority of the …
Published in International Journal of Computer Science Languages · Vol. 1, Issue 1, 2023 · pp. 1–6 Read article
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A Comparative Study on Associated Factors of Hypertension Among Working Women and Non-working Women
Abstract: Background: One in four people worldwide is affected by high blood pressure, which is also the third leading cause of illness and a significant risk factor for death. Compared to non-working women, employed women had a higher prevalence of hypertension. This might be attributed to various factors such as job-related stress, lack of relaxation, and lack of physical activity. Method: Quantitative approach was adopted. To investigate the related determinants of …
Published in International Journal of Women's Health Nursing And Practices · Vol. 1, Issue 1, 2023 · pp. 09–14 Read article
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Effect of Chemically Treated Plant Cellulose on Mechanical, Fatigue and Fracture Toughness Behaviour of Polyester Composite
Abstract: In this research study, the effect of chemically treated plant cellulose on the mechanical, fatigue, and fracture toughness behaviour of polyester composites was investigated. Ramie plant cellulose fibers were used as the reinforcing material, and polyester resin was used as the matrix material. Three different chemical treatment processes, namely alkalization, acetylation, and etherification, were used to adapt the superficial chemistry of the fibers and advance their compatibility with the polyester …
Published in Journal of Polymer & Composites · Vol. 11, Issue 3, 2023 · pp. 21–29 Read article
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Evaluating the Performance of Mobile Air Compressor Component of Radiator Unit using the Application of Reliability
Abstract: The application of reliability to monitor and predict the performance of mobile air compressor component of radiator unit was considered in this research. This study demonstrated some of the root causes of the radiator unit failure as effect of temperature and the nature of coolers used, because these two parameters cause corrosion, affect shortage on fluid level and in turn influence the internal heat generated by radiator unit of the …
Published in International Journal of Pollution: Prevention & Control · Vol. 1, Issue 1, 2023 · pp. 39–43 Read article
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Adoption of Proprietary Online Exam Proctoring Software Using Multimedia Analytics System
Abstract: This research focuses on the effects of online proctoring in facilitating the online test procedure for prospects, as well as how these tools affect engagement and learnability, as well as a retrospective investigation of other online examinations now in demand and a comparison of both. As a researcher, we learned that online proctoring is essential not only for a smooth examination process, but also for the cautious management of a …
Published in International Journal of Mobile Computing Technology · Vol. 1, Issue 1, 2023 · pp. 25–29 Read article
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Uncovering the Comparative Efficacy of Antiviral Drugs and Caricapapaya Phytocompound as VP2H inhibitors in Ebola virus: An Insilico Molecular Docking Analysis
Abstract: The Ebola virus is a fatal disease that transmits from wild animals to humans. Infected individuals' body fluids such as spit, blood, perspiration, faeces, blood, saliva, breast milk, sperm, or fomites can transmit Ebola. Adhesion to cell membranes and penetration into the host organism are essential aspects in viral growth. The presence of VP24, as well as nucleoproteins and structural proteins, is necessary for nucleocapsid formation and integration. The inhibition …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 1, Issue 2, 2023 · pp. 62–78 Read article
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Identification of Secondary Metabolites from Zingiber officinale as Inhibitors for Keap 1-Nrf2 small Molecules through Molecular Docking Techniques
Abstract: Objective: Therapeutic plants aid in treating cancer-based cell signaling pathways and preventing certain risk factors. Zingiber officinale has a variety of anti-inflammatory characteristics also contributing to enhanced immunity, reducing cancer risk and used to target the KEAP NRF2. When overexpressed in response to oxidative stress and DNA damage, elevates the risk of developing multiple cancers. NRF2 cellular sensors, which also control and coordinate their expression aid in defending healthy cells …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 1, Issue 2, 2023 · pp. 35–48 Read article
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A Study to Assess the Awareness of the Breast Cancer Screening Among Teacher Training Students in Selected Teacher Training Institutions at Mysuru with the View to Conduct Educational Program
Abstract: Background: Cancer is one of the major causes of death both in developed and developing countries. Breast cancer is defined by the uncontrollable proliferation of cells within the breast, encompassing different forms of cancer that impact the breast tissue. The majority of breast cancer cases manifest as painless lumps, while a smaller percentage may exhibit additional symptoms. Breast cancer is amenable to almost complete care if detected in its early …
Published in International Journal of Oncological Nursing and Practices · Vol. 1, Issue 1, 2023 · pp. 17–31 Read article
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A Study to Assess the Existing Hand Washing Practices with Soap and Water Among Women at Critical Times in Selected Families of (Kitte 1-7) Field Practice Area of Community Medicine, SGRD, Vallah, Amritsar
Abstract: Handwashing is the most important thing to prevent and control the illness and avoid the spread of disease. There is greater need regarding awareness of handwashing at critical times to reduce the prevalence of infections and from communicable diseases. However, there is a proper method to ensure all bacteria are removed. It is a technique of rubbing the hands together for a given period of time with soap and water. …
Published in International Journal of Emergency and Trauma Nursing and Practices · Vol. 1, Issue 1, 2023 · pp. 1–6 Read article
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Rural Settlement: A Case of Barauli Village
Abstract: We see that there is a considerable change in their style when come with the same in urban areas. Life and living of rural people is viewed in terms of demography, employment and asset structure, agriculture and allied activities, rural poverty and livelihood, social and cultural issues, institutions, government schemes/programs, village-level amenities and linkages, energy utilization patterns, recent changes and development in the villages and surrounding areas, issues related to …
Published in International Journal of Rural and Regional Development · Vol. 1, Issue 1, 2023 · pp. 20–47 Read article
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To Assess the Effectiveness of Structured Teaching Program on Nosocomial Infection and Its Prevention Among Staff Nurses Working in Shri J.G. Co-Operative Hospital Society, Ghataprabha, Karnataka
Abstract: Aims: To evaluate staff nurses’ knowledge of nosocomial infections. To examine the impact of a systematic teaching curriculum on staff nurses’ ability to avoid nosocomial infections. Furthermore, to ascertain the relationship between staff nurse pre-test knowledge and specific demographic factors. Methods: In order to investigate and evaluate the staff nurses’ level of knowledge regarding nosocomial infection prevention, an evaluatory research approach was used for this study. Pre-experimental design was determined …
Published in International Journal of Evidence Based Nursing And Practices · Vol. 1, Issue 1, 2023 · pp. 8–11 Read article
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A Study of Composite Concrete Using Palm Oil Fuel Ash (POFA) as a Partial Replacement for Cement in Self Compacting Concrete
Abstract: Due to its flexibility at young ages and its capacity to be moulded into any necessary structural form and shape, concrete is the most commonly used construction material. For concrete to be workable and to have the necessary strength and durability, thorough compaction utilising vibration is typically necessary. Large numbers of voids are caused by inadequate concrete compaction affecting the structural strength and long-term toughness. Self-Compacting Concrete (SCC) offers a …
Published in Journal of Polymer & Composites · Vol. 11, Issue 1, 2023 · pp. 76–86 Read article
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Analysis of Fibre Reinforced Beams
Abstract: There has been research into the flexural behaviour of composite beams with a variety of fibre layer depths, all of which were designed using the balancing section and the limit state design idea. The fibre depth is estimated to be 112 mm (d = 112 mm), with the first three dimensions being 94.44 mm (d1 = 94.44 mm), 46.12 mm (d2 = 22.35 mm), and 22.35 mm (d3) respectively. The …
Published in Journal of Polymer & Composites · Vol. 11, Issue 4, 2023 · pp. 53–59 Read article