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354 articles for “therapeutics methods”
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Inhibition of PI3K/Akt/mTOR Signaling Pathway by Vitis Vinifera Phytocompounds: A Promising Strategy for Supressing Colorectal Cancer Growth and Metastasis
Abstract: Objectives: Colorectal cancer was not typically identified a few decades ago. Today, with almost 900 000 fatalities each year, it is the fourth most dangerous cancer in the world. Colorectal cancer is responsible for about 10% of all cancer diagnoses annually and cancer-related deaths worldwide. It is the second most common type of cancer in women and the third most common type in men. Incidence and death are roughly 25% …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 1, Issue 2, 2023 · pp. 64–75 Read article
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A Review on Therapeutic Utilities and Purificatory Procedure of Gunja (Abrus precatorius Linn.) as Described in Ayurveda
Abstract: AbstractGunja (Abrus precatorius Linn.), belonging to the family Fabaceae, has been used by the Ayurvedic physicians, for management of different disease conditions. It comes under the upavisha (semi-poisonous) group in Ayurvedic pharmacopoeia. It is a slender, perennialclimber with long, pinnate leaves that twines around trees, shrubs and hedges. In this review, an endeavour has been made to explore the therapeutic utilities of Gunja, its formulations and its different methods of …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 2, Issue 1, 2013 · pp. 1–11 Read article
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Drug Discovery and Design: Focus on computational approaches used in the discovery and design of new drugs
Abstract: Computational approaches have revolutionized the field of drug discovery and design, offering efficient and cost-effective strategies for identifying and developing new therapeutics. This review article explores the application of computational methods in drug discovery, with a focus on virtual screening techniques, molecular docking, molecular dynamics simulations, and quantitative structure-activity relationship (QSAR) models. Virtual screening plays a crucial role in narrowing down large chemical libraries by utilizing ligand-based and structure-based approaches. …
Published in Research and Reviews : Journal of Computational Biology · Vol. 12, Issue 1, 2023 · pp. 26–30 Read article
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Pharmaceutical and Analytical Study of Kasis w.r.t. Different Shodhan Methods
Abstract: In Rasa shastra, the minerals are categorized as maharasa, uparasa and sadharana rasa based on different criteria. Kasis is categorized under uparasa. Kasis is very important mineral in Ayurvedic text. For proper usage of drug and to make it free from impurities, shodhan (~purification) process is essential. Shodhan not only purify the drug but also add therapeutic properties and make suitable it for further procedure. In classical text several methods …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 6, Issue 1, 2017 · pp. 27–31 Read article
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A Comprehensive Review on Therapeutic Utilities and Purificatory Procedures of Strychnos nux-vomicaLinn. (Kupeelu) as Described in Indian Systems of Medicine
Abstract: Strychnosnux-vomica Linn. (Loganiaceae), known as Kupeelu in Ayurveda, has been commonly employed in Ayurvedic pharmacopoeia since long. It is a deciduous tree widely distributed in India and found throughout topical India and additionally in Sri Lanka, Thailand, Cambodia and Vietnam. In this review, an endeavour has been made to explore the therapeutic utilities of Strychnosnuxvomica and to put emphasis on especially different methods of purificatoryproceduresas mentioned in Ayurveda. It is …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 1, Issue 1-3, 2012 · pp. 11–18 Read article
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Harmonizing Philosophies: An In-Depth Exploration of Homeopathic Case Management through the Lenses of Dr. Boenninghausen, Dr. Kent, and Dr. Boger
Abstract: This article examines the distinct yet converging philosophies of three pivotal figures in homeopathy: Dr. Boenninghausen, Dr. James Tyler Kent, and Dr. Cyrus Maxwell Boger. Each of these practitioners has significantly influenced homeopathic practice through their unique approaches to case management, symptom evaluation, and remedy selection. By analyzing a case of membranous dysmenorrhea drawn from Dr. Kent's archives, we applied methodologies from each of these pioneers, revealing how their philosophical …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 11, Issue 3, 2024 · pp. 6–12 Read article
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Review on Computer-Aided Drug Design in RAS Inhibitor Discovery
Abstract: This review explores the utilization of computer-aided drug design (CADD) methodologies in the discovery of inhibitors targeting the RAS pathway, a pivotal signaling cascade implicated in various cancers. Through an extensive examination of computational tools, methodologies, challenges, and recent advancements, this review aims to provide insights into the role of CADD in accelerating RAS inhibitor discovery. The discovery of effective inhibitors targeting the RAS pathway is of paramount importance in …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 11, Issue 3, 2024 · pp. 7–14 Read article
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Surajmukhi (Helianthus annuus L.): Medicinal Importance in Unani Literature and Modern Evidence
Abstract: Helianthus annuus L. (Sunflower), belonging to the family Asteraceae, is a well-recognized plant in both traditional and modern systems of medicine. In Unani medicine, it is described under the name “Shams-ul-Nahar,” attributed with specific Mizaj (temperament) and pharmacological actions. The plant is considered to possess a hot and moist temperament (Har Ratab), and different parts, including its seeds, oil, and leaves, have been employed in classical formulations. Sunflower seeds are …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 14, Issue 3, 2025 · pp. 68–75 Read article
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Nutritional, Preventive, and Therapeutic Potential of Ma-ul-Shae’er (Barley Water) in the Unani System of Medicine: A Holistic Viewpoint
Abstract: In the Unani methodology of managing diseases, Ilaj-bil-Ghiza (dietotherapy) serves as a foundational principle. The initial course of treatment for any ailment entails prescribing specific diets or regulating the quality and quantity of food intake. In recent times, there has been a heightened public awareness regarding the health advantages of functional foods and nutraceuticals for disease prevention and overall well-being. Unani medicine provides a methodical classification of food, taking into …
Published in Research and Reviews: A Journal of Medicine · Vol. 14, Issue 1, 2024 · pp. 18–25 Read article
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Nuclear Medicine: A Boon to Society
Abstract: AbstractNuclear medicine is a rapidly developing branch of medicine which uses radioisotopes for diagnostic imaging and therapy. All nuclear medicine investigations and therapeutic procedures require highly specialized equipment. Nuclear imaging is a method of producing images by detecting radiation from different parts of the body after a radioactive tracer material is administered. The images are digitally generated on a computer and transferred to a nuclear medicine physician, who interprets the …
Published in Journal of Nuclear Engineering & Technology · Vol. 7, Issue 2, 2017 · pp. 1–3 Read article
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In Silico Molecular Docking of Indigofera tinctoria Phytocompounds to Target EGFR/ERK and FGFR/FGF Pathway Proteins Involved in Prostate Cancer
Abstract: Objective: Prostate cancer being the second major cause of cancer-related deaths in males, affects the small walnut-shaped gland below the bladder called the prostate gland. The epidermal growth factor protein (EGFR), cascade protein (ERK), and fibroblast growth factor proteins (FGFR and FGF) are involved in the different signaling pathways that lead to the formation of different products, that are responsible for the progression of cancer and thus can be considered …
Published in International Journal of Molecular Biotechnological Research · Vol. 1, Issue 1, 2023 · pp. 34–56 Read article
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Non-Small Cell Lung Cancer: Types, Pathogenesis, Diagnosis, and Novel Therapeutic Strategies
Abstract: Non-small cell lung cancer (NSCLC) is the most prevalent type of lung cancer, accounting for over 85% of all cases globally. It remains one of the primary causes of cancer-related death due to its rapid progression, few early symptoms, and late detection. The three main forms of non-small cell lung cancer (NSCLC) are adenocarcinoma, squamous cell carcinoma, and giant cell carcinoma; each has a unique histology, prognosis, and response to …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 2, 2026 · pp. 07–22 Read article
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Exploring Chocolate’s Potential: A Review of Its Role in Drug Delivery and Health Benefits
Abstract: The abstract explores the versatile nature of chocolate, highlighting its role as a medium for drug delivery systems due to its resistance to microbial growth and rich nutritional profile. Medicated chocolate, infused with drugs, offers a palatable solution to enhance patient compliance, particularly among children, while stimulating serotonin production for added therapeutic benefits. Cocoa, abundant in polyphenols, contributes to chocolate's health advantages, including cholesterol reduction and cardiovascular health. Scientific evidence …
Published in Trends in Drug Delivery · Vol. 11, Issue 2, 2024 · pp. 16–24 Read article
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Valeton Phytoconstituents from Curcuma Phaeocaulis as Prion Protein Mutant V210I Inhibitors: A Computational Docking and Virtual Screening Study
Abstract: Objective: Creutzfeldt-Jakob disease (CJD), a neurological disorder that is sporadic, fatal, communicable, and worsens rapidly, is caused by abnormal folding of prion proteins. Identifying and assessing the potential of phytocompounds from the Curcuma phaeocaulis Valeton plant as a new therapeutic candidate aimed at the treatment of CJD is the objective of this research article. Methods: In this experiment, we assessed outcomes following an in-silico assessment to design a new oral …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 1, Issue 2, 2023 · pp. 1–16 Read article
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A Review of Brief Study on Nyctanthes arbor-tristis
Abstract: Nyctanthes arbor-tristis, commonly called Parijat or Night-Flowering Jasmine, is a medicinal shrub with significant therapeutic value. This article provides a detailed examination of the plant’s pharmacological effects, traditional applications, phytochemical composition, and botanical features, along with its potential for therapeutic use. Known for its longstanding role in Ayurvedic and other traditional medical practices, Nyctanthes arbor-tristis has been traditionally used to treat a wide range of ailments, with recent studies confirming …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 12, Issue 2, 2025 · pp. 24–30 Read article
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Multitarget Molecular Docking Using Curcuma longa Phytocompounds for Polycystic Ovary Syndrome Treatment
Abstract: Objective: The primary goal of this research is to understand and describe specific aspects of molecular interaction, it includes studying various aspects such as binding affinity, binding mode, and stability of the ligand-protein complex. Molecular docking is a computational technique used to predict the preferred orientation of one molecule to a second when bound together to form a stable complex. In this study, molecular docking will be employed to stimulate …
Published in International Journal of Molecular Biotechnological Research · Vol. 2, Issue 1, 2024 · pp. 15–28 Read article
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Evaluation of Medication Adherence in Patients with Type 2 Diabetes Mellitus: A Mixed- Methods Approach
Abstract: Background: Medication adherence refers to how closely an individual follows the prescribed medication regimen. It is essential for achieving desired therapeutic outcomes and improving patient health. Inadequate adherence can result in the deterioration of health conditions, higher mortality rates, and increased healthcare expenses. Diabetes mellitus, being a chronic condition, demands ongoing medical care not only to prevent the onset of serious complications but also to manage them effectively once they …
Published in International Journal of Community Health Nursing And Practices · Vol. 3, Issue 1, 2025 · pp. 28–35 Read article
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Formulation Development and Evaluation Technique for Immediate and Modified Release Capsule
Abstract: The development and evaluation of formulations for immediate-release (IR) and modified-release (MR) capsules represent a critical aspect of pharmaceutical dosage form design, offering distinct advantages in terms of drug release profiles and therapeutic outcomes. This study focuses on the formulation strategies, techniques, and evaluation methods used to develop both IR and MR capsules. Immediate-release capsules are designed to disintegrate quickly in the gastrointestinal tract, ensuring rapid drug absorption, while modified-release …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 3, Issue 1, 2025 · pp. 1–9 Read article
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Curcumin: A Review on Methods for Enhancing Its Bioavailability
Abstract: Curcumin is a natural polyphenolic compound which plays an important role in every biological need from kitchen to drugs. Besides its too many applications, curcumin limits its therapeutic value due to its less bioavailability, rapid excretion and metabolism. This review presents the work of various researchers in the field of enhancing the bioavailability of curcumin. Keywords: Curcumin, bioavailability, methods Cite this ArticleRuchika Goyal, Sandeep Jain, Ashwani Kumar. Curcumin: A Review …
Published in Trends in Drug Delivery · Vol. 3, Issue 3, 2016 · pp. 37–41 Read article
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In Vitro Screening of Antibacterial Potentiality of Some Important Flowers’ Extracts Against Some Pathogenic Bacteria
Abstract: Normal 0 false false false EN-US X-NONE X-NONE MicrosoftInternetExplorer4 The present investigation was carried out to screen and evaluate the antibacterial activities of different flowers, namely, Calendula officinalis, Rosa damacena, Hibiscus rosa-sinensis, Datura stramonium, Bougainvillea stabilis, and Vinca rosea. These flowers were screened for potential antibacterial activity against some important bacterial Gram negative and Gram positive bacteria strains, namely Escherichia coli, Salmonella typhi, Staphylococcus aureus, and E. faecalis. Dried leaf …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 1, Issue 3, 2011 · pp. 9–19 Read article