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78 articles for “retrospective”
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Comparative Effectiveness of Surgical and Nonsurgical Management for Patients with Single Level Lumbar Disc Herniation in terms of Symptom Severity and Quality of Life
Abstract: Background: Sciatica is one of the most severe forms of low back pain, with a lifetime prevalence of approximately 30 percent. Aim: To assess the short-term and long-term efficacy of surgical and conservative care in the incidence of sciatic symptoms and quality of life in standard clinical settings among patients with lumbar disc herniation. Material and Method: It was a retrospective study conducted at the Medical Trust Hospital, Kochi, India. …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 10, Issue 1, 2020 · pp. 25–29 Read article
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Malignancies during Pregnancy – A Case Series and a Brief Review of Literature
Abstract: Although occurrence of malignancy in pregnancy is rare, it accounts for a third of all maternal deaths during gestation. The advances in reproductive medicine and deliberate postponement of pregnancy till a later age may show a rise in the incidence of malignancies in pregnancy in future. Lack of standard guidelines is a major hurdle in the management of cancer in pregnancy. Our aim was to do a retrospective analysis of …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 1, Issue 2, 2012 · pp. 13–20 Read article
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Adjuvant Treatment in Carcinoma of Endometrium: Where Do We Stand?
Abstract: Endometrial cancer is one of the most common gynecological malignancy worldwide. Though there are a large number of completed prospective and retrospective studies, adjuvant treatment remains poorly defined, mainly due to the heterogeneity in selection criteria, different treatment approaches and low recurrence rates in good risk early stage disease. This article comprehensively covers the different risk stratification approaches and the current concepts and evidences in tailoring of adjuvant treatment in …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 5, Issue 3, 2016 · pp. 22–29 Read article
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Correlation of Ki-67 Score with Nottingham Histological Grading in Carcinoma Breast: A Single Institution Experience
Abstract: Though it is reasonably well established that Ki-67 positivity is an independent predictor of ultimate prognosis and course of carcinoma breast and its recurrence, many lacunae exist. Ki -67 score correlation with histological grading will establish importance of nuclear antigen Ki-67 as prognostic factor in Indian population. This study was aimed to assess histological grading of breast carcinoma by Nottingham Grading System (Modified Scarff- Bloom- Richardson system) and to correlate …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 6, Issue 1, 2017 · pp. 1–5 Read article
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The Risk of Second Malignant Tumors after Definitive Treatment of Nasopharyngeal Carcinoma: Three Case Reports and Literature Review
Abstract: Introduction: Patients with head and neck squamous cell carcinoma (HNSCC) have an increased incidence of developing second malignant tumors (SMTs). This may possibly be explained by the concept of “field cancerization” or “condemned mucosa syndrome”, implying the importance of other risk factors like smoking, alcohol consumption, genetic factors and viral infections. However, risk factors for SMTs have not been documented well, especially in nasopharyngeal carcinoma (NPC). Objective: Evaluate the presence …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 6, Issue 2, 2017 · pp. 15–20 Read article
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An Overview of 98 Cases of Idiopathic Granulomatous Mastitis
Abstract: Background: Granulomatous mastitis is an uncommon, benign, chronic inflammatory condition of breast of uncertain etiology. The clinical features mimic tuberculosis and breast cancer that leads to diagnostic and therapeutic dilemma. Its optimal management is still unclear with high recurrence rate. Purpose: The purpose of this study is to present the clinico-pathological features of patients with Granulomatous mastitis and our experience with the medical and surgical treatment of these patients. Methods: …
Published in Research and Reviews : Journal of Surgery · Vol. 7, Issue 1, 2018 · pp. 5–9 Read article
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Post-operative Wound Sepsis and Prophylactic Antibiotic
Abstract: Background and Objectives: Post-operative wound sepsis has been an area of prime interest as tackling it has been a surgeon’s primary role. They have been treating patients in sepsis and preventing sepsis in their operative work. With the advent of modern antibiotics, rate of incidence hasreceded. Timing of antibiotic administration is critical to efficacy. The aim of this study is to evaluate the incidence of post-operative wound infection in A.J. …
Published in Research and Reviews : Journal of Surgery · Vol. 7, Issue 3, 2018 · pp. 9–15 Read article
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Role of Diagnostic Laparoscopy in Chronic Abdominal Pain and Its Therapeutic Value
Abstract: The aim of this study was to evaluate and establish the role of diagnostic laparoscopy in unexplained chronic abdominal pain and its therapeutic value. Diagnostic laparoscopy apart from visualizing the entire abdominal cavity, allows us to take precise biopsy. Laparoscopy also offers therapeutic solutions for multiple reasons of abdominal pain. The study covered 110 patients with history suggestive of chronic abdominal pain for 3 months or more duration, undiagnosed despite …
Published in Research and Reviews : Journal of Surgery · Vol. 7, Issue 3, 2018 · pp. 16–20 Read article
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Initial Diversion in Hirschsprung’s Disease: Loop versus End Colostomy. Does it Make a Difference?
Abstract: Background: Staged surgery for Hirschsprung’s disease involving initial stoma formation with biopsies to find the level of aganglionosis and subsequent pull-through procedure like Duhamel’s Pull through is the most recommended management protocol at several institutions. The nature of stoma, whether loop or end, often determines the patient’s morbidity in this approach and would also have a say in the duration and ease at the time of definitive pull-through procedure. Aims …
Published in Research and Reviews : Journal of Surgery · Vol. 8, Issue 3, 2019 · pp. 4–8 Read article
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Clinical study on dual plating for delayed unions and nonunions of distal 1/3 and diaphyseal-metaphyseal transition of humerus
Abstract: Background: The best treatment for delayed union and non-union at distal 1/3 and metaphyseal-diaphyseal transition of humerus is not well established. We collected retrospective and prospective outcomes data for patients undergoing open reduction and internal fixation for delayed union and non-union of distal 1/3 and metaphyseal-diaphyseal transition of humerus with use of conventional mono-lateral or dual plating. Methods and Material: Over a 2-year period, 35 patients underwent open reduction and …
Published in Research and Reviews : Journal of Surgery · Vol. 9, Issue 2, 2020 · pp. 10–15 Read article
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Comparison between two severity classificaitons in patients with acute cholecystitis
Abstract: Background and objective: Assessment severity helps clinicians to guide appropriate treatment and minimumize adverse outcome. The objective of our study was to comparison between TG13 severity system and EGS grade system for predicting clinical outcomes in acute cholecystitis. Patients and method: This is a retrospective single-center study which enrolled patients who were admitted to pyongsong medical university hospital between February 2020 and October 2021. Tokyo 2013(TG 13) severity classification and …
Published in Research and Reviews : Journal of Surgery · Vol. 12, Issue 2, 2023 Read article
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Pattern of Injuries in Cases of Alleged Rape Victim
Abstract: One of the most atrocious crimes in present society is rape. Rape has become now a major problem for administration all over the world (Verma 1979). This study was done in the department of Forensic Medicine and Toxicology, Assam Medical College and Hospital, Assam from 1st Nov 2010 to 31st Oct. 2011. Out of 171 numbers of Sexual Offences cases brought for medical examination in this department, a total 102 …
Published in Research and Reviews: A Journal of Toxicology · Vol. 8, Issue 1, 2018 · pp. 14–17 Read article
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A Statistical Analysis of Railway Traffic Fatalities brought for Medico-Legal Autopsy
Abstract: The Indian Railway Network is the fourth largest network in the world after USA, Russia and China. Railways have been an essential part of the Indian demography since its inception during the British rule. It provides effective means of transport and supply of essential commodities through length and breadth of the country. Railway was first introduced in Assam in 1881 from Dibrugarh to Margherita for transportation of tea and coal. …
Published in Research and Reviews: A Journal of Toxicology · Vol. 8, Issue 2, 2018 · pp. 8–14 Read article
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Adverse Events Associated with Oral First-in-Man Administration of New Chemical Entities Compared with Placebo – An Analysis of 14 Single- and Multi-Dosing, Double-Blind, Placebo-Controlled Studies
Abstract: This investigation is a retrospective analysis of the adverse events (AEs) associated with oral administration of new chemical entities (NCEs)for the first time in humans. We gathered data from 14 single- and multiple-dosings of FIM NCE studies conducted in our centre over a period of 5 years. In total, 452 subjects were dosed. A total of 2280 doses were administered. Active medication was given on 1763 dosing occasions and placebo …
Published in Research and Reviews: A Journal of Toxicology · Vol. 2, Issue 3, 2012 · pp. 1–6 Read article
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Pattern of Poisoning, Management and Antidote Availability in St. Paulo’s Specialized Hospital Addis Ababa, Ethiopia
Abstract: Poisoning is the contact with a substance that results in toxicity. It can be deliberate or accidental. Antidotes are substances opposing the harmful effect of poisons and are cornerstones in the management of poisoning. Availability of antidotes highly affects the effective poisoning management. To assess the poisoning management in relation to an antidote availability. A retrospective study was used to assess the practice of poisoning management and antidote availability in …
Published in Research and Reviews: A Journal of Toxicology · Vol. 5, Issue 3, 2015 · pp. 8–12 Read article
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Sudden Natural Deaths in and around Guwahati: An Autopsy Based Study
Abstract: Death occurring within 24 h of the onset of terminal symptoms is defined as sudden death. It is frequently associated with allegations of foul play. A retrospective study of sudden natural deaths in an around Guwahati from 2016 to 2018 was conducted from the medico-legal autopsy cases done at Guwahati Medical College and Hospital Guwahati. A total of 9835 autopsy cases were done during those 3 years. Out of a …
Published in Research and Reviews: A Journal of Toxicology · Vol. 9, Issue 3, 2019 · pp. 29–33 Read article
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Understanding the Efficacy of Homoeopathy in treatment of Parasomnia
Abstract: AbstractParasomnias are a group of sleep disorders characterized by abnormal, unpleasant motor, verbal or behavioural events that occur during sleep or wake. Their treatment shows limited success with increase in daytime somnolence. Hence, this retrospective case series of 30 cases aimed to understand the efficacy of holistic homeopathic approach for the treatment of Parasomnia. In this study 64% of the patients subjective assessment showed satisfactory control and reduction in frequency …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 7, Issue 1, 2020 Read article
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An Analysis of Machine Learning Models for Early Cardiac Risk Stratification
Abstract: The paper shows an in-depth study of machine learning and artificial intelligence solutions to early cardiac risk stratification which has a crucial necessity because cardiovascular disease (CVD) prediction remains a significant issue that needs to be improved beyond the conventional risk score. Since CVD is the most serious disease killer in the world, claiming 17.9 million deaths every year, there is a strong need to get the most sophisticated predictive …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 13, Issue 2, 2026 Read article