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292 articles for “conclusion”
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Drugs for Alzheimer’s Disease from Salix Alba Discovered Computationally Utilizing Virtual Screening and Docking against 1b41 Protein
Abstract: Objective : The of this research is to evaluate the feasibility of using molecular docking techniques to identify novel acetylcholinesterase, a key enzyme implicated in the pathogenesis of Alzheimer’s disease, a neurodegenerative disorder with a gradual but steady progression to death, due to the gradual accumulation of beta-plaques and neurofibrillary tangles, as well as a decline in acetylcholine levels. Due to its function in converting acetylcholine into acyl and choline …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 1, Issue 2, 2023 · pp. 07–19 Read article
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Effect of Mindfulness-Based Yoga Practices on Anxiety and Attention Level Among High School Children in a Selected High School, Bhubaneswar, Odisha
Abstract: Background: In a world filled with endless pressures and expectation, school-aged children often find themselves navigating through a labyrinth of stressors and anxiety. from the moment they wake up their tiny minds are bombarded with worries about exams, social interaction.it is in these moments of chose that the ancient practice of yoga emerges as a gentle beacon of hope, offering solace and tranquility to these young souls. The study main …
Published in International Journal of Evidence Based Nursing And Practices · Vol. 1, Issue 2, 2023 · pp. 1–8 Read article
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A Molecular Docking Study: Targetting HIV-1 Integrase Protein Against Selected Phytocompounds from Calophyllum Lanigerum
Abstract: Objectives: The most common form of HIV that causes AIDS is HIV-1. The World Health Organization has estimated roughly 75 million plus HIV-1 infections till date and roughly 40 million deaths (as of 2021). Thus, this study was done to identify natural compounds from Calophyllum lanigerum, a medicinal plant largely endemic to South-East Asia, to inhibit the spread of this disease. It did so by using molecular docking methods, Lipinski …
Published in International Journal of Molecular Biotechnological Research · Vol. 1, Issue 2, 2023 · pp. 43–55 Read article
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Molecular Docking Study: Targeting mycobacterium leprae ML2640 Protein Using Active Compounds from Coscinium fenestratum
Abstract: Objectives: Leprosy is an infectious disease in skin, peripheral nerve and mucosa of upper airway. Around 70% of this infection is caused by Mycobacterium leprae, which was discovered during1873. Multi drug therapy is used for the treatment, still multiple drug resistance and reactions has been reported among patients. Hence, this work focused on identifying bioactive compounds from Coscinium fenestratum that can target mycobacterium leprae ML2640 protein by in-silico approach. Method: …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 1, Issue 2, 2023 · pp. 21–33 Read article
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A Study to Assess the Satisfaction Level of Children on Parent–Child Relationship Among Adolescent Girls Studying at Selected Educational Institutions in Honavar, Uttara Kannada
Abstract: Background: A strong parent-child relationship (PCR) is essential for a child’s overall development. This study aimed to explore the quality of parent-child relationships, particularly with fathers, among Indian adolescent girls. While societal attitudes have evolved, concerns remained about whether female children receive the same love, respect, and care as their male counterparts. Methodology: This research used a quantitative approach with a descriptive design. A total of 253 adolescent girls from …
Published in International Journal of Women's Health Nursing And Practices · Vol. 1, Issue 2, 2023 · pp. 14–20 Read article
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Effect of Lifestyle Counseling for Women with Gestational Diabetes on Fetal and Maternal Outcomes at Assiut University
Abstract: Gestational diabetes mellitus is a serious and often ignored risk to the health of mothers and children. Aim of the Study: To assess the effect of lifestyle counseling among women with gestational diabetes on fetal and maternal outcomes at Assiut University. Materials and Method: Antenatal care clinics hosted a pre-test and post-test for a quasi-experimental study. Sample: A total of 365 women in total attended antenatal care clinics. Setting of …
Published in International Journal of Women's Health Nursing And Practices · Vol. 1, Issue 2, 2023 · pp. 21–35 Read article
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Assessment of the Impact of a Structured Educational Program on PCOS Knowledge Among Adolescent Girls in a Chosen Area of Tarn Taran District, Punjab
Abstract: Polycystic ovary syndrome (PCOS) is a health condition characterized by elevated levels of androgen hormones, irregular menstrual patterns, and the existence of small cysts on one or both ovaries. The disorder can be morphological or biochemical. Prevention of PCOS includes lifestyle modifications that are to manage weight, exercise, and dietary changes. Aim and Objectives: The main goal of this study was to assess the efficacy of a structured educational program …
Published in International Journal of Women's Health Nursing And Practices · Vol. 1, Issue 2, 2023 · pp. 36–41 Read article
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Investigating the Impact of Robotics and Automation on Manufacturing Technology
Abstract: Automation and automated machines have dramatically enhanced quality, productivity, and efficiency in industries such as manufacturing at the past few decades. The current research looks at the ways robotics and automation are impacting industrial technologies. The investigation offers an in-depth analysis of the advantages and difficulties connected with the incorporation of robots and automation in industrial processes by evaluating pertinent literature, case studies, and statistics. Conclusions of this research effort …
Published in International Journal of Manufacturing and Production Engineering · Vol. 1, Issue 1, 2023 · pp. 33–38 Read article
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Extrapolations of Periwinkle Secondary Metabolites as Multitarget Inhibitor of Breast Cancer Proteins
Abstract: Objective: Breast cancer is considered one of the most common and dangerous forms of cancer. It is a significant public health issue on a global scale. The study estimates that 10.0 million people will die from cancer this year, and 19.3 million people will develop the disease overall (BC). In this computation approach, nowadays emphasizes new drug discovery, the target protein epidermal growth factor receptor (EGFR) (5UGB), estrogen receptor (ER) …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 1, Issue 1, 2023 · pp. 36–49 Read article
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Inhibition of PI3K/Akt/mTOR Signaling Pathway by Vitis Vinifera Phytocompounds: A Promising Strategy for Supressing Colorectal Cancer Growth and Metastasis
Abstract: Objectives: Colorectal cancer was not typically identified a few decades ago. Today, with almost 900 000 fatalities each year, it is the fourth most dangerous cancer in the world. Colorectal cancer is responsible for about 10% of all cancer diagnoses annually and cancer-related deaths worldwide. It is the second most common type of cancer in women and the third most common type in men. Incidence and death are roughly 25% …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 1, Issue 2, 2023 · pp. 64–75 Read article
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Tinospora Sinensis Compounds for Zika Virus Targets 5JRZ and 5KVD In Silico Screening: A Potential Approach to Preventing Guillain-Barre Syndrome
Abstract: Objective: GBS is a very rare kind of disease but at the same time, it is very dangerous too. The study estimates that people who are suffering from zika virus infection are more prone to GBS. According to surveys, 1 out of 4000 people got affected by this disease, and the scariest part of this disease is that there is no cure available. In this computational era drug discovery is …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 1, Issue 2, 2023 · pp. 1–15 Read article
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Valeton Phytoconstituents from Curcuma Phaeocaulis as Prion Protein Mutant V210I Inhibitors: A Computational Docking and Virtual Screening Study
Abstract: Objective: Creutzfeldt-Jakob disease (CJD), a neurological disorder that is sporadic, fatal, communicable, and worsens rapidly, is caused by abnormal folding of prion proteins. Identifying and assessing the potential of phytocompounds from the Curcuma phaeocaulis Valeton plant as a new therapeutic candidate aimed at the treatment of CJD is the objective of this research article. Methods: In this experiment, we assessed outcomes following an in-silico assessment to design a new oral …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 1, Issue 2, 2023 · pp. 1–16 Read article
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Effectiveness of Sensitization Program on Knowledge of School Children Regarding Refractive Errors
Abstract: The human eyes are portals of absorbing divine knowledge from the surrounding world. These two precious pearls need to take proper care throughout to taste life. The eye care starts right from birth onward and becomes keenly required in children's school age as they use these gifts for intense learning. The neglected care in the initial years may trouble them with various visual disorders and disturb their studies too. Well-structured …
Published in Recent Trends in Infectious Diseases · Vol. 1, Issue 1, 2024 · pp. 13–20 Read article
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A Study to Assess the Effectiveness of Video-assisted Teaching Programme on Knowledge Regarding Prevention and First Aid Management of Snakebite Among Mahatma Gandhi National Rural Employment Guarantee Scheme (MGNREGS) Workers in Selected Areas at Wayanad
Abstract: This study aimed to assess the impact of a video-assisted instructional program on the awareness of snake bite prevention and first aid practices among MGNREGS workers in Meppadi Panchayath, Wayanad. Using a quasi-experimental one-group pre-test post-test research approach, the study included 60 participants selected through convenient sampling. The participants' demographics revealed a varied distribution, with the majority falling within the 36–45 year age bracket (35%) and having an educational background …
Published in International Journal of Emergency and Trauma Nursing and Practices · Vol. 1, Issue 2, 2023 · pp. 9–13 Read article
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Effect of Nebulization With 3% Hypertonic Saline for Airway Clearance on Mechanically Ventilated Patients Admitted in ICUs of Pt. B.D. Sharma, PGIMS, Rohtak
Abstract: Background of the Study: The ability to breathe artificially prolongs life in many situations. Patients requiring mechanical breathing in the intensive care unit are more likely to have complications and even death due to a variety of interconnected causes. As a result, it became critical to rapidly ventilate in the safest and most efficient manner available. Intubated patients have benefited from nebulized suctioning, as it improves lung clearance and decreases …
Published in International Journal of Emergency and Trauma Nursing and Practices · Vol. 1, Issue 2, 2023 · pp. 20–27 Read article
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A Study to Assess the Effectiveness of Awareness Programme on Knowledge Regarding Health Problems Related to Smart Phone Addiction Among Adolescents Studying in a Selected School, Bangalore, Karnataka
Abstract: Aim: This study assesses the effectiveness of an awareness program on adolescents' knowledge of health problems related to smartphone addiction. Objectives: (1) Evaluate adolescents' understanding of health issues linked to smartphone addiction. (2) Measure the impact of the awareness program on their knowledge by comparing pre-test and post-test scores. (3) Investigate correlations between pre-test knowledge and sociodemographic variables. Method: A quantitative evaluative approach was used. The one-group pre-test post-test research …
Published in International Journal of Evidence Based Nursing And Practices · Vol. 1, Issue 2, 2023 · pp. 9–13 Read article
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Assessing the Child–Parent Relationship Between Working and Non-working Mothers in a Selected Community of Bhubaneswar
Abstract: Introduction: Two categories of mothers exist: those who work outside the home, referred to as working mothers, and those who stay at home, often described as housewives. Working mothers may allocate quality time to their children, even if the amount of time is not necessarily large. On the other hand, non-working mothers not only manage household responsibilities but also provide care for their children and the entire family. Methods: A …
Published in International Journal of Evidence Based Nursing And Practices · Vol. 1, Issue 2, 2023 · pp. 27–33 Read article
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Evaluating Epidemiological and Physical Risk Factors in the Development of Chemotherapy-induced Peripheral Neuropathy (CIPN): An In-depth Systematic Review and Meta-analysis
Abstract: Background of study: Chemotherapy-induced peripheral neuropathy (CIPN) encompasses a range of adverse effects caused by various cytotoxic medications and stands as a primary source of pain among individuals who have survived cancer. In instances of pronounced and sudden CIPN, it might become necessary to diminish chemotherapy dosages or discontinue their application. Currently, no efficacious strategy exists for proactively preventing CIPN, managing established chronic CIPN is constrained, and the risk factors …
Published in International Journal of Oncological Nursing and Practices · Vol. 1, Issue 2, 2023 · pp. 10–21 Read article
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Oral Self-examination: An Approach for Early Recognition of Oral Cancer Among Factory Workers: An Experimental Study
Abstract: Background: Cancer is a worldwide concern and ranks among the most dreaded illnesses across the globe. Oral cancers are one common cancer among all cancers. Objectives: To measure the existing knowledge concerning oral self-examination for timely recognition of oral cancer among factory workers and to develop and administer a planned health education programme of oral self-examination for early recognition of oral cancer among factory workers. 40 factory workers were selected …
Published in International Journal of Oncological Nursing and Practices · Vol. 1, Issue 2, 2023 · pp. 22–26 Read article
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Impact of Palliative Care Intervention on Knowledge, Attitude and Practice Regarding Nursing Care Issues in Caregivers of Head and Neck Cancer Patients at Hospice
Abstract: Aim: The primary aim is to assess Knowledge, Attitude, and Practice (KAP) regarding nursing care issues in caregivers of Head and Neck Cancer (HNC) patients admitted at hospice. Secondary aim is to observe the impact of providing information and teaching skills on nursing care issues to caregivers. Materials and methods: A cross-sectional study was prospectively carried out involving 33 caregivers of hospice-admitted patients with head and neck cancer. A self-designed, …
Published in International Journal of Oncological Nursing and Practices · Vol. 1, Issue 2, 2023 · pp. 27–35 Read article