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685 articles for “conclusion”
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Exploration of 5-Hydroxybowdichione Flavonoids As Inhibitors of Dengue Virus Ns5 RNA-Dependent RNA Polymerase Using Molecular Docking Approach
Abstract: Objectives: Human lives are now seriously threatened by dengue fever, which is brought on by the dengue virus (DENV). Aedes aegypti mosquitoes, which reproduce in still water, are the primary vectors of the arboviral virus known as dengue. It is well-recognized that phytochemicals have a high potential to eliminate bacterial, viral, and fungal infections in people. Thus, it demonstrates its inhibitory effects on the dengue virus. This study identifies some …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 1, Issue 1, 2023 · pp. 1–16 Read article
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Identification of Promising Lead Compounds from Capsicum annuum Targeting BACE-1 for Alzheimer’s Disease Therapy: A Molecular Docking Study
Abstract: Background: Alzheimer's disease (AD) is a neurodegenerative disorder affecting millions of people worldwide. Beta-secretase 1 (BACE-1) is an important therapeutic target for AD treatment. Capsicum annuum (CA) is a commonly consumed plant with potential neuroprotective properties. In this study, we aimed to identify potential lead compounds from CA that can target BACE-1 for AD therapy using molecular docking. Methods: A library of 15 compounds from CA was obtained from PubChem, …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 1, Issue 1, 2023 · pp. 40–49 Read article
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Pharmacological Management of Parkinson’s Disease: Current Therapies and Emerging Treatments
Abstract: Objective: Parkinson's disease, behind Alzheimer's, is the second most common neurodegenerative ailment and a major cause of neurological morbidity worldwide. Clinical diagnosis is made, and current management is limited to symptomatic treatments, with levodopa remaining the cornerstone of pharmaceutical therapy. In certain patient groups, deep brain stimulation of specific basal ganglia targets can provide significant clinical relief. There are currently no proven disease-modifying medicines in clinical use that can halt …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 1, Issue 1, 2023 · pp. 27–39 Read article
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Molecular Docking and Pharmacokinetic Profiling of the Phytocompounds of Jatropha curcas as Antagonist for Salmonella typhi
Abstract: Background: Typhoid is an infection caused by the Gram-negative bacterium, Salmonella enterica serovar typhi. The study assessed the potential use of Jatropha curcas as a typhoid fever therapy alternative to traditional medications. The ability to uncover novel drug indications for currently available medications using in silico methods has increased thanks to the wealth of pharmacological and biological knowledge that is available. Objective: In this study, we assessed the potential inhibitory …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 1, Issue 1, 2023 · pp. 67–81 Read article
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Home Interior with a Vintage style
Abstract: Vintage style originated in France and is a fusion of modern and classic styles. The vintage style is distinguished using natural materials like wood and distressed wood. Furniture and decor in a vintage style can be created with artificial aged furniture or natural materials. Conclusion, Vintage interior design has always been a popular and appealing trend, as well as a fun way for people to express themselves while decorating their …
Published in International Journal of Rural and Regional Development · Vol. 1, Issue 1, 2023 · pp. 48–57 Read article
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Understanding the Level of Knowledge and Attitudes of Pregnant Women on Use of Complementary and Alternative Medicine (CAM)
Abstract: Background: The utilization of complementary and alternative medicine (CAM) among pregnant women in India is on the rise. Though the pregnant women are using these therapies, they lack adequate knowledge. It is the responsibility of the health care provider to identify the knowledge to promote healthy practices and to avoid harmful practices. Method: For this investigation, a quantitative method was used. The level of knowledge and attitude of pregnant women …
Published in International Journal of Midwifery Nursing And Practices · Vol. 1, Issue 1, 2023 · pp. 25–30 Read article
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A Study on Breast-feeding Self-Efficacy and Its Associated Factors Among Mothers
Abstract: Introduction: The process through which a kid is fed human breast milk is known as breastfeeding. Breastfeeding has a significant impact on disease prevention and health promotion. It helps to increase bonding with baby and mother. Oestrogen, progesterone, prolactin, and oxytocin are the four primary hormones that contribute to the production of breastmilk. A modifiable element that can improve breastfeeding success and duration is breastfeeding self-efficacy. Aim: To evaluate mothers' …
Published in International Journal of Midwifery Nursing And Practices · Vol. 1, Issue 1, 2023 · pp. 31–36 Read article
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A Comparative Study on Associated Factors of Hypertension Among Working Women and Non-working Women
Abstract: Background: One in four people worldwide is affected by high blood pressure, which is also the third leading cause of illness and a significant risk factor for death. Compared to non-working women, employed women had a higher prevalence of hypertension. This might be attributed to various factors such as job-related stress, lack of relaxation, and lack of physical activity. Method: Quantitative approach was adopted. To investigate the related determinants of …
Published in International Journal of Women's Health Nursing And Practices · Vol. 1, Issue 1, 2023 · pp. 09–14 Read article
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Impact of Counseling on Cancer Patient’s Depression Level
Abstract: Introduction: When given the dreaded and possibly fatal cancer diagnosis, patients go through a great deal of pain. Depression is one of the psychiatric problems that can arise after a cancer diagnosis. The purpose of the current research is to evaluate how well counseling therapy can lower depression levels in cancer patients. Methodology: Geetanjali Hospital in Udaipur provided the data for this study, which utilized a single-group, quasi-experimental analysis employing …
Published in International Journal of Oncological Nursing and Practices · Vol. 1, Issue 1, 2023 · pp. 1–5 Read article
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Identification of Secondary Metabolites from Zingiber officinale as Inhibitors for Keap 1-Nrf2 small Molecules through Molecular Docking Techniques
Abstract: Objective: Therapeutic plants aid in treating cancer-based cell signaling pathways and preventing certain risk factors. Zingiber officinale has a variety of anti-inflammatory characteristics also contributing to enhanced immunity, reducing cancer risk and used to target the KEAP NRF2. When overexpressed in response to oxidative stress and DNA damage, elevates the risk of developing multiple cancers. NRF2 cellular sensors, which also control and coordinate their expression aid in defending healthy cells …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 1, Issue 2, 2023 · pp. 35–48 Read article
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Scope of Nurse Led Preventive Oncology Clinic in India
Abstract: India holds immense potential and a promising future for the extensive implementation of nurse-led preventive oncology clinics, considering its substantial burden of cancer-related morbidity and mortality. The healthcare system in India is not equipped enough to cater to the growing needs of the population, and there is a lack of preventive services, particularly for cancer. In this context, nurse-led preventive oncology clinics can play a pivotal role in addressing the …
Published in International Journal of Oncological Nursing and Practices · Vol. 1, Issue 1, 2023 · pp. 12–16 Read article
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A Structure-based Design Approach to Catharanthus roseus Phytoconstituents as Potential Inhibitors of B-Cell Lymphoma 6 Protein
Abstract: Objectives: Lymphoma is a cancerous disease. It develops into millions of people worldwide. Identify the naturally active compounds from Catharanthus roseus, they have multiple values in the medicinal field of Siddha, and Indian Ayurveda are used as a disease-preventing agent. Drug illness prediction, toxicity prediction, statistical information, molecular docking, as well as absorption, distribution, metabolism, and excretion (ADME) analysis are used to predict the fit ligand as a drug. Methods: …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 1, Issue 2, 2023 · pp. 14–34 Read article
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A Study to Assess the Awareness of the Breast Cancer Screening Among Teacher Training Students in Selected Teacher Training Institutions at Mysuru with the View to Conduct Educational Program
Abstract: Background: Cancer is one of the major causes of death both in developed and developing countries. Breast cancer is defined by the uncontrollable proliferation of cells within the breast, encompassing different forms of cancer that impact the breast tissue. The majority of breast cancer cases manifest as painless lumps, while a smaller percentage may exhibit additional symptoms. Breast cancer is amenable to almost complete care if detected in its early …
Published in International Journal of Oncological Nursing and Practices · Vol. 1, Issue 1, 2023 · pp. 17–31 Read article
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The Effectiveness of Honey Application for Oral Mucositis in Cancer Patients: A Review of Randomized Controlled Trials
Abstract: Background: Oral mucositis (OM) is a prevalent and distressing adverse outcome of cancer therapies, including chemotherapy and radiation therapy. It is an inflammatory ailment that impacts the mucous membrane inside the mouth, tongue, gums, and throat. OM can cause pain, discomfort, difficulty swallowing, and in severe cases, it can lead to infection and delayed cancer treatment. Although there are various treatments available, such as painkillers, anti-inflammatory drugs, and topical anesthetics, …
Published in International Journal of Oncological Nursing and Practices · Vol. 1, Issue 1, 2023 · pp. 32–39 Read article
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Thoracolumbar Spine Surgery: Peri-operative Nursing Care Needs and Quality of Life
Abstract: Aim and Objective: To explore the nursing care needs of the patients after thoracolumbar spine surgery during preoperative, post-operative, home care and to assess the quality of life. Design: An exploratory study. Methods: The study was conducted among 50 patients who had undergone thoracolumbar spine surgery in neurosurgery units of tertiary care hospital from July 2018 to September 2020. The nursing needs were assessed by interviewing participants telephonically using an …
Published in International Journal of Orthopedic Nursing and Practices · Vol. 1, Issue 1, 2023 · pp. 13–23 Read article
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Quality of Sleep Among Patients with Chronic Renal Failure
Abstract: Renal failure is the partial or complete impairment of kidney function. Inability to eliminate metabolic waste products and water, along with functional disruptions in all bodily systems, result in the condition known as renal failure. Renal failure can be categorized as either acute or chronic. Chronic renal failure refers to the gradual and irreversible deterioration of the nephrons in both kidneys. It is characterized by either kidney damage or a …
Published in International Journal of Emergency and Trauma Nursing and Practices · Vol. 1, Issue 1, 2023 · pp. 22–28 Read article
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A Study to Evaluate the Effectiveness of a Structured Teaching Program on the Knowledge and Practice of Road Traffic Accident Prevention Measures Among Teenagers
Abstract: An investigation to evaluate the impact of a structured educational program on the understanding and implementation of strategies for preventing road traffic accidents among teenagers. Introduction: Accident is an accidental injury, passing or property harm happening in a grouping of occasions. Accidents don't simply occur; they are neglectfulness, indiscretion, carelessness, and flashing absence of focus. Accidents have turned into a significant reason for dismalness and mortality, particularly among the grown-ups …
Published in International Journal of Emergency and Trauma Nursing and Practices · Vol. 1, Issue 1, 2023 · pp. 29–40 Read article
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An Overview of Construction Market of Sri Lanka
Abstract: This paper provides an overview of the construction market in Sri Lanka, with a focus on the Colombo region. It discusses the strengths, weaknesses, opportunities, and constraints of the construction market in the country. The main drivers of the construction sector are identified, including urbanization and infrastructure development. The paper explores the ease of embarking on international construction projects within the Colombo region, noting that while the Sri Lankan government …
Published in International Journal of Rural and Regional Development · Vol. 1, Issue 1, 2023 · pp. 58–64 Read article
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Knowledge About Reproductive Health Among Adolescent Girls in Selected Colleges: A Cross-sectional Study
Abstract: Introduction: Future generations' health is greatly influenced by the reproductive health of adolescent girls. For adolescent females to live healthy lives and safeguard against reproductive health issues, knowledge about reproductive health is crucial. The study's primary goal is to evaluate the pre-existing knowledge of reproductive health among adolescent girls studying in selected colleges. Methodology: A descriptive cross-sectional research with 200 teenage college-bound girls was done. The questionnaire was pre-designed and …
Published in International Journal of Women's Health Nursing And Practices · Vol. 1, Issue 1, 2023 · pp. 27–31 Read article
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Perceptions and Attitude of Registered Nurses Towards Professionalism in Nursing from Selected Hospitals of Guntur District, Andhra Pradesh: A Comparative Study
Abstract: Background: Nursing professionalism refers to a collection of principles that are essential to raising the standard of patient care while enhancing the methodology, norms, and judgement that direct nursing activities on a daily basis. The main objective of the study is to assess the perceptions and attitude of registered nurses towards professionalism in nursing. Materials and Methods: A comparative descriptive research design adopted for this study. The study conducted at …
Published in International Journal of Evidence Based Nursing And Practices · Vol. 1, Issue 1, 2023 · pp. 1–7 Read article