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308 articles for “Method validation”
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Molecular Docking of Nigella Sativa Phytocompound as Inhibitors of Transcription Factors NF-KB Implicated in Rheumatoid Arthritis
Abstract: Objectives: Nigella sativa, a plant considered around the world as the most treasured nutrient-rich herb for centuries together in different civilizations, is exceptionally known for its high levels of antioxidant properties. Free radical intensification due to oxidative stress plays a key role in the pathogenesis of rheumatoid arthritis by activating the NF-KB protein that regulates the expression of the genes involved in inflammation. Methods: This study involves in-silico approach to …
Published in International Journal of Molecular Biotechnological Research · Vol. 2, Issue 2, 2024 · pp. 42–55 Read article
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Unlocking the Healing Powers of Aṣl Khāliṣ (Honey): Exploring Its Functional and Therapeutic Potential
Abstract: Aṣl Khāliṣ (honey) as a natural product has grabbed the attention of researchers as a reciprocal and indispensable remedy. Honey has been used to heal both internal and external ailments for much longer than medicine has existed. Unani scholars have mentioned its action in classical literature as a nutritional agent, as well as a natural food supplement with therapeutic antibacterial, anti-inflammatory, cleansing, deobstruent, lithotryptic, and wound-healing properties. According to contemporary …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 12, Issue 3, 2025 · pp. 17–23 Read article
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Anti-hyperglycemia Effects of Plant Secondary Metabolites Towards PKA/CREB Pathway Activation in Diabesity
Abstract: Objective: Diabesity, the amalgamation of diabetes and obesity, presents a significant global health challenge. This research carefully examines how plant secondary metabolites influence glucose regulation in diabetes using the PKA/CREB pathway, paying particular attention to diabesity—the combination of diabetes and obesity. Understanding the complex ways in which these metabolites affect metabolic health will help to identify new treatment approaches for managing diabetes and its associated problems. By conducting a thorough …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 2, Issue 1, 2024 · pp. 33–50 Read article
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Time Series Sales Forecasting Using ARIMA Model
Abstract: Sales forecasting is a critical application in various industries and presents one of the most challenging problems worldwide. One method of prediction involves identifying patterns in historical data, where the outcome is known in advance and can be validated using more recent data. If a pattern consistently leads to the same outcome, it can be considered a genuine relationship. This method is highly flexible and can be utilized with diverse …
Published in International Journal of Algorithms Design and Analysis Review · Vol. 2, Issue 1, 2024 · pp. 17–27 Read article
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Evaluate the Impact of a First Aid Module on the Knowledge and Skills Related to First Aid Management Among Nursing Students at Gian Sagar College of Nursing, Ramnagar, Rajpura, Punjab
Abstract: Introduction: First aid refers to the immediate and temporary care provided to individuals who are injured, ill, or wounded before professional medical assistance becomes available. Since accidents can occur unexpectedly, having fundamental first aid knowledge is invaluable. It enables individuals to deliver prompt, lifesaving assistance and prevent complications until expert care arrives. Training nursing students in first aid is particularly important, as it equips them to preserve life, prevent further …
Published in International Journal of Emergency and Trauma Nursing and Practices · Vol. 3, Issue 2, 2025 · pp. 42–55 Read article
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Machine Learning Approach to Predict the Performability and Emissions of Diesel Engine Fueled with Doped Biodiesel Blend
Abstract: Enhancing the performability and emission characteristics of diesel engines has been a difficult task in light of growing concerns about global warming and other negative effects, as diesel accounts for 70% of global energy demand. In this study, engine performance and exhaust emissions for various fuel blends were thoroughly evaluated using machine learning techniques to predict engine emission and performance behavior. We focused on biodiesel blend and nanoparticle additive concentration …
Published in International Journal of Mechanical Dynamics and Systems Analysis · Vol. 3, Issue 1, 2025 · pp. 1–12 Read article
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Integrating Human-Centric Principles into Machine Design: Ergonomic and Safety Enhancements in Mechanical Systems
Abstract: The integration of human-centric design (HCD) principles into mechanical systems has become increasingly critical in contemporary machine design. As machines become more complex and operate within high-interaction environments, the need for design strategies that prioritize human safety, usability, and comfort has intensified. This review explores how ergonomic insights, safety standards, and user experience (UX) considerations influence the physical configuration, control mechanisms, and operational safety of mechanical systems across industrial, healthcare, …
Published in Trends in Machine design · Vol. 12, Issue 2, 2025 · pp. 33–37 Read article
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Electromagnetic Propulsion Train for Future Transportation
Abstract: The Electromagnetic Propulsion Train project focuses on the development and analysis of a prototype system that achieves linear motion through the application of controlled electromagnetic forces. Unlike conventional railway systems that rely primarily on mechanical drive mechanisms such as wheels, axles, and traction motors, this project explores an alternative propulsion approach based on electromagnetic interaction. In this system, a sequence of electromagnets is strategically positioned along the track to generate …
Published in International Journal of Electro-Mechanics and Material Behaviour · Vol. 3, Issue 2, 2025 · pp. 25–31 Read article
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Dynamic Modeling and Simulation of Multi-Body Mechanical Systems: A Comprehensive Review of Methods, Tools, and Applications
Abstract: The dynamic modeling and simulation of multi-body mechanical systems (MBS) form a cornerstone in modern mechanical engineering, enabling in-depth analysis of the kinematic and kinetic behaviors of interconnected rigid and flexible components. MBS are foundational to a range of critical applications, from automotive suspensions and aerospace mechanisms to robotics and biomechanical structures. As system complexity and performance requirements increase, accurate and scalable modeling techniques are essential for both design validation …
Published in International Journal of Mechanical Dynamics and Systems Analysis · Vol. 3, Issue 1, 2025 · pp. 35–42 Read article
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An Automation Detection for Sign Language Using AI
Abstract: Sign language recognition has attracted considerable interest because of its ability to facilitate communication between the deaf community and the public, thereby bridging communication divides. Traditional approaches to sign language recognition often face challenges in accurately interpreting the complex and nuanced gestures inherent in sign languages. However, recent advancements in deep learning techniques have shown promising results in improving the accuracy and robustness of sign language recognition systems. This study …
Published in Recent Trends in Programming languages · Vol. 11, Issue 1, 2024 · pp. 1–14 Read article
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Simultaneous Determination And Stability Indicating Method For Telmisartan, Metoprolol Succinate And Cilnidipine In Tablet Dosage Form.
Abstract: There are several medicinal agents available for antihypertensive activity. Telmisartan, metoprolol and cilnidipine are among them. Quantitative and qualitative analysis plays a pivotal role in safeguarding patients. Here, the estimation of these drugs was performed by using the chromatographic technique RP-HPLC. It was conducted with Phosphate buffer (pH 3.5 ± 0.01): Methanol (50:50 v/v) mobile phase. The system was operated at 1 ml/min. Drug volume to the system was 20μl. …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 11, Issue 1, 2024 · pp. 32–38 Read article
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Evaluation of Credit Risk of Bank Customers with a Hybrid Approach of Data Mining Techniques
Abstract: Credit risk poses the most significant threat to financial and monetary institutions. Banks strive to offer loans that generate high returns while minimizing risk. Achieving this requires the ability to accurately identify and classify credit customers, both individuals and legal entities, according to their likelihood of fully meeting their obligations. This classification is done using relevant financial and non-financial criteria. The primary goal of this study is to assess the …
Published in Journal of Artificial Intelligence Research & Advances · Vol. 11, Issue 3, 2024 · pp. 63–81 Read article
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Optimizing Parameters for Dry Sliding Wear Control in Stir-Cast AA7050/SiC Composites
Abstract: Using a pin-on-disc tribometer, this study examined the dry sliding wear behavior of AA7050/SiC composites. The production of this metal matrix composite was achieved through the stir-casting process, which involved an initial step of melting the AA7050 alloy, followed by the careful introduction of silicon carbide (SiC) particles, stirring to achieve uniform dispersion, and finally, casting the molten mixture. Wear rate (WR) was determined by three operational parameters: SiC reinforcement …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 1624–1635 Read article
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Design and Analysis of Smart Solar EV Charging System
Abstract: The rising demand for electric vehicles (EVs) has generated an urgent requirement for sustainable and advanced charging systems. This study delineates the design and analysis of an intelligent solar EV charging system intended to reduce dependence on the grid and optimize the utilization of renewable energy. The system incorporates a solar photovoltaic (PV) array, battery energy storage, and an IoT-enabled smart controller to optimize power delivery. A Maximum Power Point …
Published in Journal of Power Electronics and Power Systems · Vol. 16, Issue 1, 2026 · pp. 06–15 Read article
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A Study to Assess the Awareness of the Breast Cancer Screening Among Teacher Training Students in Selected Teacher Training Institutions at Mysuru with the View to Conduct Educational Program
Abstract: Background: Cancer is one of the major causes of death both in developed and developing countries. Breast cancer is defined by the uncontrollable proliferation of cells within the breast, encompassing different forms of cancer that impact the breast tissue. The majority of breast cancer cases manifest as painless lumps, while a smaller percentage may exhibit additional symptoms. Breast cancer is amenable to almost complete care if detected in its early …
Published in International Journal of Oncological Nursing and Practices · Vol. 1, Issue 1, 2023 · pp. 17–31 Read article
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Chemical Reactor Design and Analysis: A Review
Abstract: Chemical reactors play a critical role in industries such as oil and gas, chemical processing, and power generation, where they operate under extreme pressure and handle highly toxic, compressible fluids. The growing need for alternative energy sources has led to an increased demand for vessels capable of withstanding high pressure and temperature, especially in the chemical and petroleum industries. Recent innovations in chemical reactor technology have concentrated on creating new …
Published in Recent Trends in Fluid Mechanics · Vol. 12, Issue 2, 2025 · pp. 49–59 Read article
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Vibration Analysis of Functionally Graded Piezoelectric Actuators: A Comprehensive Review
Abstract: Recent research has been concentrated on a thorough investigation of the vibration evaluation of functionally graded piezoelectric materials (FGPM), shedding light on the potential for enhancing structural optimization and controlling deflections and vibrations. Functionally graded piezoelectric material is a type of advanced composite material possessing diverse characteristics that allow for customized mechanical and electrical responses. The existing body of academic work extensively addresses the vibration analysis of functionally graded piezoelectric …
Published in Journal of Polymer & Composites · Vol. 13, Issue 1, 2025 · pp. 426–440 Read article
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Solar Panel Defect Detection Using Geospatially-Aware Deep Learning framework
Abstract: Large-scale photovoltaic (PV) systems demand reliable inspection techniques to maintain efficiency, as manual methods remain labor-intensive and inconsistent. This study introduces a geospatially informed deep learning framework for defect detection and localization in PV panels from drone and satellite imagery. The framework incorporates an adaptive tiling mechanism that adjusts tile boundaries according to object size, reducing information loss and enhancing detection performance. In addition, coordinate transformation between image pixels and …
Published in Journal of Remote Sensing & GIS · Vol. 17, Issue 2, 2026 Read article
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Analyzing the Sheet Metal Extrusion Process Using Finite Element Analysis
Abstract: A wide range of sheet metal forming techniques has been developed to make it easier to produce intricate 3D objects. However, the knowledge still isn't sufficient. The sheet metal extrusion method was examined in this research as one of the common sheet-bulk metal manufacturing technologies. Consideration of the flow-stress curve's impact across a broad range of plastic strain and ductile damage played a pivotal role in constructing a realistic finite …
Published in International Journal of Fracture Mechanics and Damage Science · Vol. 1, Issue 1, 2023 · pp. 13–25 Read article
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A Review on Predicting Wear and Friction of PTFE Composites - Fillers to Machine Learning Models
Abstract: Polytetrafluoroethylene (PTFE) composites, a self-lubricating material with low friction, became an indispensable material in engineering applications where load carrying capacity and wear are crucial. The pure PTFE has poor mechanical strength and wear resistance which can be enhanced by the addition of fillers in appropriate volume fraction. The wear performance is dependent on various factors such as fillers, operating parameters, environmental conditions as well as manufacturing attributes. This makes the …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 114–128 Read article