Search
297 articles for “Disease Identification”
-
Introduction to Biological Networks and their Contributions to Systems Biology
Abstract: Biological networks provide a conceptual framework to represent and analyze the intricate interconnections among the numerous components that make up living systems. This review paper elucidates the foundational principles of networks and their diverse applications in systems biology, highlighting their crucial role in understanding the inherent complexity of biological processes. Utilizing graph theory, these networks represent entities like genes, proteins, and metabolites as nodes, with their interactions depicted as edges. …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 2, Issue 1, 2024 · pp. 53–70 Read article
-
Interaction of Bioactive Component of Aframomum melegueta on Molecular Docking
Abstract: Computational mimicry of the structure of large complexes created by di- and poly-interaction of molecules has been termed molecular docking. The purpose of molecular docking is the prediction of the three-dimensional structures of interest, this is due to that docking only produces plausible candidate structures. The docking was carried out between the bioactive compounds against 5α-reductase, 3β-hydroxy-steroid dehydrogenase, and 17β-hydroxy-steroid dehydrogenase of returned binding energy, BE (kcal/mol) between -5.9 and …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 2, Issue 1, 2024 · pp. 51–60 Read article
-
Metabolites in Modern Medicine: Decoding the Future of Health and Diseases
Abstract: The end products of many metabolic processes in cells are called metabolites. Each reaction contributes a specific metabolite. Metabolites act as fingerprints of on-going biological processes. Constant changes in cellular composition due to both environmental and internal factors. By analysing the types and presence of metabolites, scientists can effectively reconstruct the inner workings of a cell or organism. In the past, analysing metabolites was a slow and tedious process, often …
Published in Emerging Trends in Metabolites · Vol. 1, Issue 2, 2024 · pp. 1–13 Read article
-
Analysis of White Matter, Gray Matter, and Cerebrospinal Fluid Alterations in Neurological Disorders: A Deep Learning Approach
Abstract: This paper investigates the role of white matter (WM), gray matter (GM), and cerebrospinal fluid (CSF) alterations in the pathophysiology of neurological disorders, including Alzheimer’s disease, Parkinson’s disease, schizophrenia, and epilepsy. By leveraging advanced deep learning methodologies, we aim to automate the segmentation and analysis of brain structures from MRI scans, enabling a more detailed and precise evaluation of their roles in disease progression. These techniques allow for the identification …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 14, Issue 3, 2024 · pp. 21–27 Read article
-
An Experimental Study to Assess the Effectiveness of Planned Teaching Program Regarding Pelvic Rocking Exercise and Dry Ginger on Knowledge and Attitude Regarding Dysmenorrhea
Abstract: Objective: Dysmenorrhea is characterized by painful menstrual cramps originating from the uterus and is a common gynaecological condition affecting women of all ages and nationalities. Primary dysmenorrhea refers to menstrual pain without any underlying organic disease, while secondary dysmenorrhea occurs due to an identifiable medical condition. Common causes of secondary dysmenorrhea include endometriosis, fibroids, adenomyosis, endometrial polyps, pelvic inflammatory disease, and the use of intrauterine contraceptive devices. Methodology: Experimental research …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 14, Issue 1, 2024 · pp. 6–10 Read article
-
Artificial Intelligence in Microbiological Research: Methods, Applications and Implications
Abstract: Artificial Intelligence (AI) is revolutionising microbiological research by enabling the rapid analysis of complex biological data and improving the accuracy, efficiency, and reliability of scientific investigations. Recent advances in machine learning, deep learning, and bioinformatics have transformed AI into a powerful tool for studying microorganisms, their genetic composition, evolutionary patterns, and interactions with hosts and the environment. AI-driven computational models can process large and complex datasets far more efficiently than …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 16, Issue 2, 2026 Read article
-
Early Detection of Heart Disease using Machine Learning Techniques
Abstract: Coronary illness stays one of the main sources of death around the world. Exact expectations of coronary illness can altogether work on quiet results by empowering early intercession and customized treatment plans. Throughout the course of many recent years, AI (ML) methods have been extensively investigated for anticipating coronary illness, attribuFig to their remarkable capacity to analyze complex data patterns and generate precise predictions based on historical clinical records. With …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 12, Issue 3, 2025 · pp. 34–45 Read article
-
A Review of Recent Advancements in Machine Learning and Deep Learning Approaches for Pet Diseases Prediction
Abstract: This systematic study assesses recent developments in Machine Learning (ML) and Deep Learning (DL) approaches to predict pet diseases. With the increasing role of Artificial Intelligence (AI) in pet healthcare, this study identifies recent research trends, limitations, and future directions. A comprehensive search was done using the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines in selecting 20 relevant studies from over 300 articles published between 2020 and …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 14, Issue 3, 2025 · pp. 1–6 Read article
-
Complications with Malware Identification in IoT and an Overview of Artificial Immune Approaches
Abstract: An immunity is facilitated by lymphocyte T&B-cells; that possess a wide range of T&B-cell; receptors, respectively. These cells can identify and react to pathogens and diseased cells by presenting peptide antigens by means of significant histocompatibility complexes (MHCs). The amount of data on the repertoire of adaptive immune receptors has increased dramatically in recent years because to advancements in deep sequencing. Furthermore, the presentation of peptides with MHC has been …
Published in Research and Reviews : A Journal of Immunology · Vol. 14, Issue 1, 2024 · pp. 54–62 Read article
-
AI Application in the Creation of Medications for COPD
Abstract: The crippling lung condition known as chronic obstructive pulmonary disease (COPD) is typified by a continuous restriction of airflow, which results in increased respiratory dysfunction and a reduced quality of life. The rising incidence of COPD worldwide emphasizes the pressing need for innovative pharmaceutical approaches to address the illness. Even though COPD care has advanced significantly, most current medications concentrate on symptom relief rather than disease change. This gap in …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 2, 2025 · pp. 01–05 Read article
-
Pathways in Drug Discovery and Development: From Molecular Targets to Market Approval
Abstract: A complicated, multidisciplinary, and resource-intensive process, the discovery and development of new pharmacological drugs is essential to the advancement of contemporary medicine. Finding and optimising lead chemicals comes after a disease-relevant biological target has been identified and validated. Through preclinical research in animal models, these leads are thoroughly assessed for toxicity, pharmacokinetics, safety, and efficacy. Clinical trials, which are carried out in several stages to evaluate safety, efficacy, ideal dosage, …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 13, Issue 1, 2026 · pp. 01–04 Read article
-
An Intelligent Neural Networks Approach for Monitoring of Soilless Urban Farms
Abstract: Urban agriculture is increasingly recognized as a sustainable approach to addressing food security challenges in rapidly growing and densely populated cities. Conventional soil-based farming often faces limitations such as space scarcity, excessive water consumption, and environmental degradation. To overcome these challenges, soilless farming techniques such as hydroponics and aeroponics have gained significant attention due to their efficient utilization of space, reduced water requirements, and potential for year-round crop production. However, …
Published in Journal of Water Resource Engineering and Management · Vol. 12, Issue 3, 2025 · pp. 31–37 Read article
-
Formulation Challenges in Long-acting Injectable Small Molecules: Emerging Strategies and Perspectives
Abstract: Long-acting injectable (LAI) formulations represent a transformative approach in pharmacotherapy, particularly for conditions demanding sustained drug exposure over weeks to months. Although biologics have dominated this space historically, the adaptation of LAI technology to small molecules presents a distinct and complex set of challenges rooted in physicochemical properties, manufacturing scalability, and regulatory expectations. This review systematically addresses the principal formulation barriers encountered in developing LAI small-molecule products, including aqueous solubility …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 13, Issue 2, 2026 Read article
-
A Structure-based Design Approach to Catharanthus roseus Phytoconstituents as Potential Inhibitors of B-Cell Lymphoma 6 Protein
Abstract: Objectives: Lymphoma is a cancerous disease. It develops into millions of people worldwide. Identify the naturally active compounds from Catharanthus roseus, they have multiple values in the medicinal field of Siddha, and Indian Ayurveda are used as a disease-preventing agent. Drug illness prediction, toxicity prediction, statistical information, molecular docking, as well as absorption, distribution, metabolism, and excretion (ADME) analysis are used to predict the fit ligand as a drug. Methods: …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 1, Issue 2, 2023 · pp. 14–34 Read article
-
Integrating Network Pharmacology and Molecular Docking to Investigate Boerhavia diffusa for Pancreatic Cancer Treatment
Abstract: Objective: In this study, network pharmacology was applied to determine the therapeutic effects of the bioactive compounds of Boerhavia diffusa. Network pharmacology can unearth the underlying mechanisms between drugs and the disease targets and aids in the discovery of novel medications for complex conditions such as cancer. Methods: To predict the molecular mechanisms of action of Boerhavia diffusa in the treatment of was screened using the GeneCards database. The Venn …
Published in International Journal of Molecular Biotechnological Research · Vol. 2, Issue 1, 2024 · pp. 29–49 Read article
-
Veterinary Immunology in Zoonotic Disease Control
Abstract: Zoonotic diseases, which are transmissible between animals and humans, pose a significant threat to global public health, food security, and economic stability. Veterinary immunology plays a pivotal role in understanding host–pathogen interactions, developing preventive strategies, and mitigating the impact of these diseases. Animals serve as reservoirs for a variety of pathogens, including viruses, bacteria, and fungi, which can persist asymptomatically or cause clinical disease. Understanding the immune mechanisms in both …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 14, Issue 3, 2025 · pp. 36–43 Read article
-
Drugs for Alzheimer’s Disease from Salix Alba Discovered Computationally Utilizing Virtual Screening and Docking against 1b41 Protein
Abstract: Objective : The of this research is to evaluate the feasibility of using molecular docking techniques to identify novel acetylcholinesterase, a key enzyme implicated in the pathogenesis of Alzheimer’s disease, a neurodegenerative disorder with a gradual but steady progression to death, due to the gradual accumulation of beta-plaques and neurofibrillary tangles, as well as a decline in acetylcholine levels. Due to its function in converting acetylcholine into acyl and choline …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 1, Issue 2, 2023 · pp. 07–19 Read article
-
Face Mask Detection on Real Time Images and Videos using Deep Learning
Abstract: A big change has occurred in our day-to-day lives as a result of COVID-19. One of these changes is the widespread adoption of face masks as a preventative measure against the transmission of the virus. Because of this, face mask detection has developed into an indispensable technique in a variety of contexts, ranging from public areas to industrial settings. Artificial intelligence (AI) and machine learning algorithms are utilized in the …
Published in International Journal of Electrical Machine Analysis and Design · Vol. 2, Issue 1, 2024 · pp. 22–30 Read article
-
Deep Learning -Based Dental Issue Detection
Abstract: Dentistry is vital for preserving oral health, a key component of overall wellness. Early identification of dental issues is crucial for effective treatment and avoiding further complications. Conventional approaches to diagnosing dental problems typically depend on physical examinations and visual assessments by skilled professionals, which can be both time-intensive and influenced by individual judgment.In recent years, the application of deep learning algorithms has demonstrated significant potential in automating and enhancing …
Published in Research and Reviews: A Journal of Dentistry · Vol. 16, Issue 1, 2025 · pp. 18–23 Read article
-
Assessment of Polycystic Ovarian Syndrome with Emphasis on Imaging Modalities
Abstract: Polycystic Ovarian Syndrome (PCOS) is a higly prevalent hormonal disorder that affects women during their reproductive age. It is linked to a wide range of health concerns ,including disturbances in reproductive functions, metabolic abnormalities and an increased risk of cardiovascular diseases. Ultrasonography plays a crucial role in identifying polycystic ovarian morphology, which constitutes one of the key diagnostic criteria under the Rotterdam consensus. This prospective cross-sectional observational study was conducted …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 16, Issue 1, 2026 Read article