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1882 articles for “CRISPER cas-9” (ranking capped at the first 2,000 matches — narrow the search to see the rest)
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Ayurvedic Approach in Case of Irritable Bowel Disease– A Case Study Highlighting the Efficacy and Safety
Abstract: Irritable bowel disease (IBD) is a common psychosomatic disorder that affects the gastrointestinal system, with symptoms that include cramping, abdominal pain, bloating, flatulence, and diarrhea or constipation, or both. If left untreated, it turns into chronic IBS. It can be controlled by adjusting the diet, changing the lifestyle. More severe symptoms include weight loss, diarrhea at night, bleeding from the rectum, anemia due to iron deficiency, unexplained vomiting, and pain …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 11, Issue 2, 2024 · pp. 9–13 Read article
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Crispr Cas – Revolutionizing Modern Therapies and Beyond
Abstract: CRISPR-Cas technology has emerged as a transformative tool in modern molecular biology, revolutionizing both fundamental research and clinical applications. This RNA-guided gene-editing system enables precise and efficient genomic modifications, offering unprecedented potential for addressing genetic disorders, infectious diseases, and oncological conditions through innovative therapeutic interventions. The inherent specificity and programmability of CRISPR-Cas systems have facilitated breakthroughs in diverse fields, including precision medicine, regenerative therapies, and immuno-oncology. Beyond its therapeutic applications, …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 3, Issue 1, 2025 · pp. 25–38 Read article
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Managed Pressure Drilling for Improved Well Control: A Cross-Case Comparative Study (2015–2025)
Abstract: Managed Pressure Drilling (MPD) has matured over the past decade from a specialist technique applied to challenging wells into a mainstream drilling capability spanning ultra-HPHT exploration, deepwater development, unconventional tight-gas multi-well campaigns, and naturally fractured sour-gas reservoirs. Despite this maturation, the operational question of which MPD variant should be applied to a given well has been addressed in the literature case-by-case rather than through structured comparative synthesis. This paper presents …
Published in Journal of Petroleum Engineering & Technology · Vol. 16, Issue 2, 2026 · pp. 07–12 Read article
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Lean Production using Casting Simulation to Promote FTR Approach
Abstract: When the talk is about the green production, then intention is to develop a product with first-time-right approach. Foundry desperately needs such production system, as it provides wide range of products. Even the small errors in the inputs (concept, design, raw material, process, etc.) can lead to wasted outputs [1], and invite unwanted cost of reworking. Thus, it is of extreme importance to develop the castings with FTR (first time …
Published in Journal of Production Research & Management · Vol. 3, Issue 2, 2013 · pp. 23–29 Read article
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A Review Paper on Shrinkage Defect in Investment Casting
Abstract: Investment casting is also known as lost wax casting process. It is used to make various components of machines and jewellery with good accuracy compared to other castings. It is also used to make difficult components which may not be possible by conventional casting process. Investment casting is very helpful process for higher quality requirements. But still, there are many defects occurring in the process, like shrinkage, cold run, blow …
Published in Journal of Thin Films, Coating Science Technology & Application · Vol. 4, Issue 3, 2017 · pp. 18–20 Read article
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A Case Study on R.C.C Cast in situ Pile Capacities for Flyover Foundations
Abstract: Bangladesh is a densely populated country in the world. So, for the movement of this large population needs a good transport system. Every day people are moving hundreds of kilometers for their personal and official works and using different road transport system. Reality is the roads are very narrow. The present situation says people are making traffic jams though not intentionally. People have to work or stay at home, though …
Published in Recent Trends in Civil Engineering & Technology · Vol. 4, Issue 2, 2014 · pp. 1–6 Read article
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Virtual Tooling Development and Tooling Cost Estimation for Sand Casting
Abstract: Casting is a major manufacturing process. It requires an understanding of a wide range of geometrical, material and process parameters. For producing cost effective casting, in today's market of intense competition, where the need of the hour is to develop quality products at low cost and short lead time, innovative and cost effective designs are the means to success. Early cost estimation, necessary for design-to-cost philosophy, serves as a decision …
Published in Trends in Mechanical Engineering & Technology · Vol. 7, Issue 3, 2017 · pp. 59–66 Read article
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Determinants of Constraints to Indigenous Knowledge Utilization among Cassava Farmers in Delta State, Nigeria
Abstract: AbstractThis study aimed at the determinants of constraints to indigenous knowledge utilization among cassava farmers in Delta State, Nigeria. The specific objectives were to describe the socio-economic characteristics of respondents, verify the frequencies of indigenous knowledge utilization in farming season activities and identify the constraints faced in the use of indigenous knowledge in cassava production. A simple random sampling technique involving three stages was used to select 120 respondents for …
Published in Research and Reviews : Journal of Crop science and Technology · Vol. 5, Issue 1, 2016 · pp. 35–42 Read article
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A Study and Report on Role And Impact Of Clinical Pharmacist in assessment of Prescribing Cascades In Antibiotics Usage For Infectious Diseases in Promotion of Rational Drug Usage
Abstract: ABSTRACT:A Prescription cascade occur when the healthcare providers fail to recognise that the new symptoms are actually the side effects of the medications under treatment. The study was based on the role and impact of clinical pharmacist in assessment of prescribing cascades in antibiotics usage for infectious diseases in department of general medicines and paediatric department at ESI hospital, Indiranagar, Bangalore, Karnataka, India. The main motto of the study was …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 9, Issue 3, 2022 · pp. 1–14 Read article
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Gypsum Addition in Moulding Sand to Manufacture Defect Free Tin Castings
Abstract: Sand molding is a versatile casting process that provides freedom of design with respect to size, shape, and product quality. Plaster casting is similar to sand molding process except that a plaster is substituted instead of sand. Plaster compound is composed of gypsum, which strengthens the mould. Parts made by this process are gears, valves, fittings, tooling, and ornaments. The finished product of plaster casting has a very high surface …
Published in International Journal of Fracture Mechanics and Damage Science · Vol. 1, Issue 2, 2023 · pp. 7–15 Read article
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Complex Tuberculous Meningitis: A Case Series Highlighting Rare Co-infections and Severe Complications
Abstract: This case series presents two complex cases of tuberculous meningitis (TBM) with different complications, illustrating the diverse clinical presentations and management challenges of this disease. Case 1 involves an 18-year-old female with TBM complicated by cryptococcal co-infection, while Case 2 describes a 64-year-old female with TBM complicated by obstructive hydrocephalus and secondary bacterial infections. Both patients had been on anti-tubercular therapy before presentation. Diagnostic approaches included cerebrospinal fluid analysis, cultures, …
Published in International Journal of Pathogens · Vol. 1, Issue 2, 2024 · pp. 1–7 Read article
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The potential Role of Antidepressant Medications in DNA Oxidation of Depression Disorder Cases
Abstract: Oxidative stress and DNA oxidation is a main target of different medications side effect, the current work aims to evaluate the potential role of anti-depressed medications in DNA oxidation in depression disorder cases, reactive oxygen species (ROS), total antioxidant (TAO) and 8-oxo deoxyguanine (8-oxo-dG) were detected in depressed disorder cases that treated with different medications included clomipramine, tryptizol, fluxetin, olanzapine, tryptizol with fluxetin, tryptizol with olanzapine and other types of …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 15, Issue 1, 2025 · pp. 41–47 Read article
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Comparative Study of Tire Oil and Cashew Nutshell Oil Biofuel Blends with Diesel
Abstract: We are going to compare Cashew Nutshell Oil (CNSO) diesel blend and Tire Oil diesel blend in this paper. Usually, Cashew Nutshell Oil is produced from the waste that is collected from cashew nut industry. Tire oil is the liquid fuel that is produced from waste tires. Many tests were going on to study the fire point of both CNSO and Tire oil blends. Kinematic viscosity is high in case …
Published in Journal of Automobile Engineering and Applications · Vol. 6, Issue 2, 2019 · pp. 7–12 Read article
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Artificial Neural Network Based Defect Prediction in Casting
Abstract: The main problems which are facing by most of the casting industries is loss of productivity which is due to casting defects occurred during the production time. The main casting defects are cracks, misruns, blowholes scabs and airlocks. Most of the investigations made in this area is only discussing the defects occurred after a cast is made and no method has yet been developed to prevent the defects before casting. …
Published in Journal of Mechatronics and Automation · Vol. 2, Issue 2, 2015 · pp. 33–38 Read article
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Thermal Analysis of Casting using ANSYS: A Review
Abstract: The major requirement of any foundry is to provide the high quality casting products. Since the quality is depended upon thermal stress and solidification of the casting, a thermal analysis is a key area to work on. Heat transfer coefficient is the vital element of any thermal analysis. Mould and the casting interface is the most critical area that gets affected during the solidification. Heat transfer ratio at the inter …
Published in Journal of Production Research & Management · Vol. 6, Issue 1, 2016 · pp. 19–27 Read article
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A Study of Hanging Cases in Barpeta District
Abstract: Hanging is a violent form of asphyxial death. It is widely accepted as a method of suicide due to its relative painless and rapid death. The rate of suicidal hanging cases is increasing day by day. The objective of study is to find out its demographic pattern, ligature material commonly used by the victims, post-mortem findings and to identify the causative factors. In this study of hanging cases brought for …
Published in Research and Reviews : A Journal of Immunology · Vol. 6, Issue 3, 2016 · pp. 13–16 Read article
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Determinants of Caesarean Delivery in Ayder Referral Hospital, Mekelle, Tigray, Ethiopia 2015: A Case Control Study
Abstract: Caesarean delivery rates have been increasing around the world from time to time, with current rates in developing countries comparable to other industrialized nations. International concern over such increases has prompted the World Health Organization to suggest that caesarean section rates should not exceed 15%. A study conducted in Ayder Referral Hospital indicated that the rate of caesarean section was 21.90%. The aim of the study was to assess the …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 5, Issue 1, 2016 · pp. 52–59 Read article
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Investigating the Effect of Inoculation on Microstructure of IS: 210 in Casting of Bracket: A Review
Abstract: The objective of present investigation is to review the effect of the inoculants on the microstructure of grey cast iron. Effects of the inoculants were investigated through metallurgical analysis of the matrix microstructure and the mechanical properties of the castbracket. Effect of silicon carbide and ferro-silicon at different temperature and at different weight percentage on grey cast iron is investigated. The results show that both, the SiC and the conventional …
Published in Trends in Mechanical Engineering & Technology · Vol. 7, Issue 1, 2017 · pp. 47–51 Read article
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Tracer Application in Study of Reaction Kinetics using Duolite ARA-9366B and Duolite A-638
Abstract: Radiotracer isotopes 131I and 82Br were used to study the iodide and bromide ion-isotopic exchange reactions taking place in two anion exchange resins Duolite ARA-9366B (nuclear grade) and Duolite A-638 (non-nuclear grade) under different operational parameters like temperature and ionic concentration of exchanging medium. The results of present investigation indicate an existence of strong positive linear co-relationship between amount of ions exchanged and concentration of ionic solution; while existence of …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 5, Issue 1, 2014 · pp. 34–44 Read article
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A review on Design of Cascade Vapour compression Refrigeration System
Abstract: Cascade refrigeration system is an ultra-low temperature multi-stage refrigeration systems operating at ideal low temperatures ranging from -30°c to -100°c.Cascade system is a frigid system that adopts dual refrigerants having diverse boiling points, that escape through the medium of their particular frigid cycle and are combined by a cascade heat exchanger. Cascade refrigeration systems are used for obtaining faster cooling in a much lower time than the normal vapour compression …
Published in Journal of Refrigeration, Air conditioning, Heating and ventilation · Vol. 5, Issue 3, 2018 · pp. 1–6 Read article