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559 articles for “and Toxicity.”
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Effects of Chlorpyrifos as Inducer for Oxidative Stress in Liver, Kidney and Spleen of Freshwater Fish, Pseudetroplus maculatus (Bloch, 1795)
Abstract: Chlorpyrifos is one of the most common organophosphate insecticides found abundantly in freshwater ecosystems and has been detected in agricultural and fishery products worldwide. The study focused to determine the effect of chlorpyrifos on the induction of oxidative stress in freshwater fish Pseudetroplus maculatus. Fish were exposed to sublethal concentrations (0.661 and 1.32 μg/l) of chlorpyrifos for 15 and 30 days. Activities of antioxidant enzymes and the levels of hydrogen …
Published in Research and Reviews: A Journal of Toxicology · Vol. 8, Issue 1, 2018 · pp. 20–29 Read article
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A Statistical Analysis of Cephalic Index of the Different Communities of Assam Brought for Autopsy at Department of Forensic Medicine, Gauhati Medical College and Hospital
Abstract: Cephalic Index also known as ‘Cranial Index’ or ‘Index of Breadth’ is one of the important parameters that help to differentiate human races. The cephalic index was first described by a Swedish anatomist, Anders Retzius (1796–1860) and was first used in physical anthropology in classifying ancient human remains of Europe. It is one such data obtained from skull which can aid in identification of a particular race or community, describe …
Published in Research and Reviews: A Journal of Toxicology · Vol. 8, Issue 2, 2018 · pp. 31–37 Read article
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A Statistical Analysis of Railway Traffic Fatalities brought for Medico-Legal Autopsy
Abstract: The Indian Railway Network is the fourth largest network in the world after USA, Russia and China. Railways have been an essential part of the Indian demography since its inception during the British rule. It provides effective means of transport and supply of essential commodities through length and breadth of the country. Railway was first introduced in Assam in 1881 from Dibrugarh to Margherita for transportation of tea and coal. …
Published in Research and Reviews: A Journal of Toxicology · Vol. 8, Issue 2, 2018 · pp. 8–14 Read article
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The Effects of Propylparaben on Women with Respect to Breast Cancer: A Study
Abstract: Propylparaben is a natural substance found in many plants and some insects; although it is manufactured synthetically for the industrial applications in field of cosmetics, pharmaceuticals, foods and so on. It is used as a preservative, typically found in many water-based cosmetics, commercially available pharmaceuticals and foods items, such as creams, lotions, shampoos, bath products, tablets, baked food products and so on, to reduce the activity of microorganisms. Parabens have …
Published in Research and Reviews: A Journal of Toxicology · Vol. 8, Issue 2, 2018 · pp. 38–43 Read article
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Selenium Contamination of Groundwater of Majha Belt of Punjab (India)
Abstract: Punjab is facing a crisis situation due to high levels of heavy metals in the underground water table of Punjab. Majha belt of Punjab, namely, Amritsar, Gurdaspur and Tarn Taran districts have high Arsenic and Selenium contents in groundwater. In this preliminary report, groundwater quality data pertaining to Selenium is reported. Selenium Acceptable Limit (AL) for groundwater is fixed at 0.01 mg/l (ppm) by the Bureau of Indian Standards (BIS). …
Published in Research and Reviews: A Journal of Toxicology · Vol. 8, Issue 2, 2018 · pp. 1–7 Read article
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A Research Project on Identification and Reporting of Adverse Drug Reactions in General Medicine Ward of an ESI Hospital
Abstract: Aim: The study aims at identifying and reporting the adverse drug reactions (ADRs) in general medicine ward of an ESI hospital, Bangalore, Karnataka, India. Objective: Prescription study, analysis and prevention of medication-related problems (ADRs), identifying and minimizing medication-related problems, improving patient safety initiatives, improving the patient health-related outcomes, reducing work burden of physicians, and providing better therapy to large number of patients. Methodology: Study Design: It was a prospective and …
Published in Research and Reviews: A Journal of Toxicology · Vol. 8, Issue 3, 2018 · pp. 9–14 Read article
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Speech and Language Profile in a Client Diagnosed with Drug-Induced Parkinsonism
Abstract: Drug-induced Parkinsonism (DIP) is the second-most common cause of Parkinsonism. Researchers differentiate Parkinsonism and DIP through several potent factors. Patients diagnosed with DIP exhibit characteristics such as tremors, rigidity, akinesia, postural instability etc similar to Parkinsonism but the basic difference is that the symptoms would resolve or turn better after the cessation of the drug leading to the deficits. This study deals with a 60-year-old lady diagnosed with Parkinsonism after …
Published in Research and Reviews: A Journal of Toxicology · Vol. 8, Issue 3, 2018 · pp. 34–36 Read article
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Extemporaneous Compounding: Cautions Vs Convenience
Abstract: Pharmacists are only knowledgeable and skilled healthcare professionals dedicated to compounding and preparing medications to meet the unique needs of patients. The safe and successful extemporaneous compounding of prescription products for patients’ requirement in special consideration is vital to the drug store profession. In any case, there are a lot to improvement in the situation secundum artem. It is not in the least conservative for a pharmaceutical organization to marketize …
Published in Research and Reviews: A Journal of Toxicology · Vol. 9, Issue 1, 2019 · pp. 26–43 Read article
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Selenium Contamination of Groundwater of Malwa Belt of Punjab (India)
Abstract: Punjab is facing a crisis situation due to high levels of uranium, arsenic and selenium in underground water table of Punjab. Malwa belt of Punjab, namely, Ludhiana, Ferozepur, Roop Nagar and Fatehgarh sahib districts have high selenium contents in groundwater. Selenium Acceptable Limit (AL) for groundwater is fixed at 0.01 mg/l (ppm) by the Bureau of Indian Standards (BIS). In this report, groundwater quality data pertaining to selenium in the …
Published in Research and Reviews: A Journal of Toxicology · Vol. 9, Issue 1, 2019 · pp. 13–20 Read article
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Selenium Contamination of Groundwater of Doaba Belt of Punjab (India)
Abstract: Punjab is facing a crisis situation due to high levels of uranium, arsenic and selenium in underground water table of Punjab. Doaba belt of Punjab, namely, Jallandhar, Kapurthala and Hoshiarpur districts have high selenium contents in groundwater. Selenium Acceptable limit (AL) for groundwater is fixed at 0.01 mg/l (ppm) by the Bureau of Indian Standards (BIS). In this report, groundwater quality data pertaining to selenium in the Doaba belt is …
Published in Research and Reviews: A Journal of Toxicology · Vol. 9, Issue 1, 2019 · pp. 1–8 Read article
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Assessment of Indoor Air Pollutants with Special Reference to Particulate Phase Polyaromatic Hydrocarbon in Rural Villages
Abstract: Emissions from household stoves using traditional biomass fuels such as firewood, crop residue and animal dung could have a continuing contribution to air pollution and also have adverse health impacts due to emission of different toxic pollutants. The present study was carried out in 13 household kitchens in Thavarghatta located in Shimoga district to know the level of the total suspended particulate matter (TSPM) and particulate phase polyaromatic hydrocarbons (PAHs) …
Published in Research and Reviews: A Journal of Toxicology · Vol. 2, Issue 2, 2012 · pp. 38–45 Read article
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Impact of Profenofos on Oxygen Consumption and Gill Histopathology of the Fresh Water Crab, Paratelphusa jacquemontii (Rathbun)
Abstract: In fresh water crab, gills are crucial for respiration, excretion, acid-base balance, and osmotic and ionic regulation. Profenofos, a well-known organophosphate pesticide has been in agricultural use over the last two decades for controlling pests of paddy, cotton and tobacco. In the present study, an attempt has been made to study the effect of profenofos on oxygen consumption and gill histopathology of the freshwater crab, Paratelphusa jacquemontii (Rathbun). The crabs …
Published in Research and Reviews: A Journal of Toxicology · Vol. 2, Issue 2, 2012 · pp. 46–55 Read article
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Endosulfan-Induced Hepatotoxicity and its Amelioration by Administration of Bamboo (Dendrocalamus Strictus) Seed Extract in Rats
Abstract: Endosulfan is an important hepatotoxic agent that generates free oxygen radicals in liver and the incidence of toxic injury to the liver tissue in relation to its widespread has been reported. Bamboo is rich in phenolic components which possess various bioactivities and bamboo seed extract was found to have antioxidative properties. Hence, the present study has been designed to assess the protective role of bamboo seed extract against endosulfan induced …
Published in Research and Reviews: A Journal of Toxicology · Vol. 4, Issue 1, 2014 · pp. 1–7 Read article
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Role of Endogenous and Exogenous Glutathione in the Detoxification of Free Radicals
Abstract: The aging process and disease progression are the result of cellular damage by free radicals. Our first lines of defense against free radical damage are the antioxidants. They are critical for keeping optimal health and wellbeing. The need for antioxidants becomes more critical with increased exposure to free radicals. Pollution, drugs, cigarette smoke, illness, stress, and even exercise can increase free radical exposure. The accumulation of free radicals produced from …
Published in Research and Reviews: A Journal of Toxicology · Vol. 7, Issue 1, 2017 · pp. 1–14 Read article
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A Study of Cranio-Facial Injuries in Medico-Legal Autopsies
Abstract: Injury to the cranium and face is a common finding in medico-legal autopsies. Blunt trauma to the cranium is most frequently caused by road traffic accidents, assaults, falls from height and also from impacts by machineries. However, road traffic accidents accounts for the commonest occurrence of cranio-facial injuries. International labour organization 1994 estimated that nearly 2 lacks workers die annually and 1200 lacks are injured. Studies of traumatic cranial injuries …
Published in Research and Reviews: A Journal of Toxicology · Vol. 7, Issue 1, 2017 · pp. 15–18 Read article
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A Study of Allege Rape Cases in Barpeta District, Assam
Abstract: Sexual violence regarded as a global problem, not only in the geographical sense but also in terms of age and sex. This study was carried out in the Department of Forensic Medicine, Fakhruddin Ali Ahmed Medical College and Hospital (FAAMCH), Barpeta, Assam, India. A total 580 alleged rape cases coming for examination from different part of Barpeta district of Assam in the year 2014 and 2015 were studied and data …
Published in Research and Reviews: A Journal of Toxicology · Vol. 7, Issue 1, 2017 · pp. 19–24 Read article
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Gossypetin Inhibits ROS Generation in HeLa and HepG2 Cell Lines
Abstract: Antioxidants are known for their ability to neutralize the reactive oxygen species present within the living system. These antioxidants are mainly secondary metabolites present in plant products and are generally known as nutraceuticals or bioactive compounds. Antioxidant can be categorized into many categories based upon their structure and activities like flavonoids, anthrocyanins and carotenoids. Flavonoids are heterogeneous polyphenolic compounds having beneficiary effect on human body and are also known to …
Published in Research and Reviews: A Journal of Toxicology · Vol. 7, Issue 1, 2017 · pp. 25–31 Read article
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The Effect of Vitamin C on the Reproductive Functions of Paraquat Intoxicated Male Albino Rats (Rattus norvegicus)
Abstract: Paraquat (PQ) is a bipyridylium herbicide applied around trees in Orchids and between crop rows to control broad-leaved and grassy weeds. Its oxidation results in the formation of superoxides and supernitrite species which causes damage to cellular components. Studies have implicated PQ as one of the pesticides that contributes to the reduction in male reproductive functions in humans and animals during exposure. This study, therefore, determined the antioxidant effect vitamin …
Published in Research and Reviews: A Journal of Toxicology · Vol. 4, Issue 3, 2014 · pp. 9–29 Read article
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Cytotoxic, Anthalmintic and Analgesic Activities of the Methanol Extract of Ricinus communis (Family: Euphorbiaceae)
Abstract: The aim of this study was to evaluate the phytochemical screening, cytotoxicity, anthelmintic activity and analgesic properties of the methanol extract (leaves) of Ricinus communis (Family: Euphorbiaceae). The methanol extract of the leaves showed mild cytotoxic activity with the LC50 value 6.456 µg/mL compared to vincristine sulfate (LC50 0.812 µg/mL) using brine shrimp lethality bioassay. The anthelmintic activity was performed by observing the time of paralysis and the time of …
Published in Research and Reviews: A Journal of Toxicology · Vol. 5, Issue 1, 2015 · pp. 27–35 Read article
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Differential Response by Rotenone on Human Trabecular Meshwork and HeLa Cell Lines
Abstract: Cellular response towards a particular stress condition is dependent on a number of factors including genetic makeup, microenvironmental factors, nutrient availability etc. Cells under same stress condition respond differentially and may exhibit pro-apoptotic or anti-apoptotic behavior. Two quite different cell lines—the cancerous cells of HeLa and the Human Trabecular Meshwork (HTM) cell line with very different microenvironmental requirements behave very differently towards oxidative insult due to rotenone. Study of their …
Published in Research and Reviews: A Journal of Toxicology · Vol. 5, Issue 2, 2015 · pp. 14–22 Read article