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542 articles for “(DoS)”
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A Consolidated Review on Novel Liquisolid Technique to Enhance Aqueous Solubility of Poorly Water Soluble Drugs
Abstract: Liquid technique is a novel capable method that can change the dissolution rate of water insoluble drugs. Liquid preparations such as solutions or suspensions of water unsolvable drugs in suitable non-volatile liquid vechicles can be transformed into suitable flowing as well as compressible powders by blending with selected powder excipients. It has been speculated that such systems exhibit improved release profiles. In this case, even though the drug is in …
Published in Research and Reviews : Journal of Computational Biology · Vol. 8, Issue 2, 2019 · pp. 1–4 Read article
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Internal Resorption in the Dentin-Pulpal Complex: An Etiological Link to the Metabolic Acidosis of Diabetes
Abstract: The etiology of internal resorption is not by bacteria or caries but most likely initiated from chronic pulpal inflammation (i.e., chronic pulpitis) following intrusive injury to the dental pulp by one or more of the following means: (1) Traumatic injury (i.e., the most likely etiology) which often involves the oral cavity and teeth. (2) Chemical injury may be by elevated dose fluoride use or from caustic products used in bleaching. …
Published in Research and Reviews: A Journal of Dentistry · Vol. 6, Issue 2, 2015 · pp. 1–6 Read article
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A Future Revolution in Medical/Dental Therapeutics: Medical Marijuana
Abstract: Dispensing and use of marijuana (Cannabis) and derivatives are restricted under federal statutory control in the United States as “SCHEDULE 1” substances (illegal drugs). However, at the state level (September 2016), “medical marijuana” is legal in 20 states plus “recreational marijuana” in four states and the districts of Columbia. Several other states have litigation for marijuana decriminalization on the November 2016 ballot. Pharmacotherapeutic use of marijuana and its derivatives may …
Published in Research and Reviews: A Journal of Dentistry · Vol. 7, Issue 3, 2016 · pp. 1–6 Read article
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Tranexamic Acid Mouth Rinser as a Drug of Choice among Haemostatic Agent after Tooth Extraction in Patients who are on Anti-Coagulant and Anti Platelet Medical Therapy
Abstract: Oral surgery procedure became difficult to manage in patients, who are on anti-platelet and anti-coagulant medication. Risk of thromboembolism should be balance by surgeon via reducing or stopping anti platelet and anticoagulant therapy in such patients, because there are more risk of excessive post extraction bleeding if anticoagulation or anti platelet medications are prescribed at therapeutic dose during surgical procedure. Fibrin formation mechanism become impaired in such patients, as a …
Published in Research and Reviews: A Journal of Dentistry · Vol. 12, Issue 2, 2021 · pp. 33–44 Read article
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Assessment of Knowledge, Attitude, Practice and Associated Factors of Emergency Contraceptive Pills among Female Youths in Mekelle City, Tigray Region, North Ethiopia
Abstract: For girls and young women aged 15–19, pregnancy and childbirth is the number one killer. It’s the cause of 50,000 deaths of teenage girls every year. Ensuring that adolescent girls are able to use suitable contraception to delay the age at which they first become pregnant is a key part of the family planning challenge. Around 16 million girls between the ages of 15 and 19 give birth each year. …
Published in Research and Reviews: A Journal of Health Professions · Vol. 5, Issue 1, 2015 · pp. 7–21 Read article
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Guidelines for Withdrawal of Anti-Epileptic Drugs in Seizure-Free Patients
Abstract: The ultimate goal of epilepsy treatment is to become seizure free and live a healthy life without the need to take antiepileptic drugs may cause several tricky and sometimes serious side-effects. There is no class I evidence that is based on randomized double-blind trials for withdrawal of antiepileptics in adults who become seizure-free while taking such drugs. Whether or not antiepileptic drugs should be withdrawn after a patient has been …
Published in Research and Reviews: A Journal of Health Professions · Vol. 4, Issue 1, 2014 · pp. 5–8 Read article
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Glucosamine as a Pain Reliving Agent in Planter Fasciitis
Abstract: Plantar fasciitis is the most common cause of the plantar heel pain. Its main features are a pain, tenderness mostly on the medial aspect of the calcaneum near the sole of heel. There are many conservative methods for treatment of the lantar fasciitis which include rest, massage, night splints, orthoses, injections, cast NSAID, shock wave therapy. The glucosamine is one of the nutritional product which has a good anti- properties …
Published in Research and Reviews: A Journal of Health Professions · Vol. 1, Issue 1-3, 2011 · pp. 25–29 Read article
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Therepi: A Replenishable Implanted Epicardial Reservoir
Abstract: The healthcare technology has been advancing at such a high pace which was not expected some years back. This paper is an attempt to introduce not so known, still existing and in-development phase, techniques which can revolutionize the healthcare industry in different domains. The recent technological development in coronary therapies have shown a great promise in restoring the abnormalities present in the heart after the patient experiences heart attack; certain …
Published in Research and Reviews: A Journal of Health Professions · Vol. 9, Issue 2, 2019 · pp. 12–16 Read article
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A Review on Corticosteroids: A Controversial Role in COVID-19
Abstract: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the known causative agent of coronavirus disease 2019 (COVID-19) which emerged first in Wuhan Province of China has caused catastrophic health, social, and economic crisis worldwide. Several drug therapies were used with corticosteroids being one of them, believing to exert an effect in controlling the ARDS. Use of corticosteroids in patients with COVID-19 is common in clinical practice, but the efficacy and role …
Published in Research and Reviews: A Journal of Health Professions · Vol. 12, Issue 2, 2022 · pp. 11–16 Read article
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Ozone Therapy: A New Era Paradigm
Abstract: There are evidences which suggest that ozone does have various therapeutic effects that range from disinfection of pathogens, anticancer properties, and treatment of back ailments. Due to the controlled and moderate oxidative stress produced by the reactions of ozone with several biological components, the therapeutic efficacy of ozone therapy is seen. Strength of the oxidative stress may show the line between effectiveness and toxic effect of ozone therapy. This observation …
Published in Research and Reviews : A Journal of Immunology · Vol. 8, Issue 1, 2018 · pp. 22–30 Read article
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Assessment of Adherence to Antiretroviral Therapy Among Art Users in Jimma University Specialized Hospital, Jimma Zone, Oromia Region, South West Ethiopia
Abstract: Background: HIV-associated morbidity and mortality gets substantially reduced with antiretroviral therapy (ART). Antiretroviral treatment efficacy exhibits significant inhibition of viral replication as well as viral load resulting in significant decrease in viral particles to a level where it becomes undetectable in the blood of HIV infected individuals. But, antiretroviral therapy (ART) requires high-level (>95%) adherence and adherence to antiretroviral therapy has been correlated strongly with HIV viral suppression, reduced rates …
Published in Research and Reviews : A Journal of Immunology · Vol. 8, Issue 1, 2018 · pp. 14–21 Read article
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Anti-inflammatory Activity of Leaves Fractions of Traditionally used Medicinal Plants
Abstract: Traditional plants such as Amaranthus spinusus Linn and Abutilon indicum Linn have been used in the Indian traditional system of medicine for the treatment of several diseases such as pain, inflammation, piles, toothache etc. The fractions of ethyl acetate, methanol and ethanol were tested for their anti-inflammatory activity. Ethanolic and methanolic fractions of A. indicum and A. spinusus at the doses of 200 and 400 mg/kg produced highly significant activity. …
Published in Research and Reviews : A Journal of Immunology · Vol. 8, Issue 1, 2018 · pp. 34–36 Read article
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Vaccine Candidates and Animal Models for Kala-Azar
Abstract: Kala-azar or Visceral Leishmaniasis (VL) is a serious human disease in tropical regions and rapidly emerging as an opportunistic infection in HIV patients. The available treatment against VL is associated with toxicity and drug resistance. Even though the development of vaccines against VL is received limited attention. The only successful immunization strategy in humans has been leishmanization, which is based on the development of durable immunity after recovery from infection …
Published in Research and Reviews : A Journal of Immunology · Vol. 5, Issue 1, 2015 · pp. 29–35 Read article
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Aluminum Oxide Nanoparticle-Adjuvanted Pasteurella multocida B:2 Vaccine is Potent and Efficacious and is Able with Keyhole Limpet Hemocyanin as a Marker to Differentiate Infected from Vaccinated Animals (DIVA)
Abstract: Pasteurella multocida B:2 causes hemorrhagic septicemia (HS) in bovines in Asia. For effective implementation of HS control program in India, a safe and efficacious vaccine to provide long lasting protection and allow differentiation of infected from vaccinated animals (DIVA) has to be developed. The objectives of the present study were to develop HS-DIVA vaccine with a companion immunodiagnostic test using keyhole limpet hemocyanin (KLH) as a marker, and to improve …
Published in Research and Reviews : A Journal of Immunology · Vol. 5, Issue 2, 2015 · pp. 8–16 Read article
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Over Expression of Genes at Long Arm of 21 Chromosome in Case of Down Syndrome
Abstract: Down Syndrome (DS) is a genetic disorder which is caused due to trisomy at chromosome 21 or gene dosage imbalance. DS leads to mental retardation in humans. It is a multisystem disorder as it affects several systems of our body like cardiovascular, respiratory, gastrointestinal, neurological, hematopoietic and musculoskeletal system. The principal cause of DS is unknown yet. Some factors are responsible for DS. like reproduction at advanced maternal age, folic …
Published in Research and Reviews : A Journal of Immunology · Vol. 5, Issue 2, 2015 · pp. 27–34 Read article
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Comparative Study of Vaccine for COVID-19 Available in India
Abstract: The enduring SARS-CoV-2 deadly disease has led to the focused application of resources and scientific knowledge toward the target of developing investigational vaccines to avoid COVID-19. The greatly collaborative global hard work by private industry, governments, and non-governmental organizations has resulted in several SARS-CoV-2 vaccines. In this review, we provide an overview of the description, vaccine characteristic, developers, and action of vaccine, dose & efficacy of vaccines on Covid-19.
Published in Research and Reviews : A Journal of Immunology · Vol. 11, Issue 3, 2021 · pp. 1–7 Read article
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A Research Study and Report on Clinical Pharmacy Services Provided by Doctor of Pharmacy during their Clerkship and Internship Postings to a Tertiary care teaching Hospital.
Abstract: Clinical pharmacy is defined as the area of pharmacy concerned with the science and practice of rational medication use. Aim: The study aims at implementing clinical pharmacy services by Doctor of Pharmacy during clerkship and internship postings to patients at different wards of Rajiv Gandhi Institute of Medical Sciences. Objective: Prescription study and analysis and preventing the medication related problems adverse drug reactions drug interactions, over dose), performing drug utilization …
Published in Research and Reviews: A Journal of Medicine · Vol. 8, Issue 1, 2018 · pp. 27–32 Read article
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Papillary Thyroidcarcinoma in Rats After Administration of Platinum Compounds Daily
Abstract: Papillary thyroid carcinoma (PTC) predominantly grows in a solid growth pattern with papillary projections, composed of oncocytic cells with “Orphan annie eyes” nuclei. Cisplatin or Cis-Diammine dichloroplatinum (ii) (Cl2H6N2Pt); is a divalent, inorganic and water-soluble first successful platinum containing anticancer drug, used to treat various forms of cancers. The Carboplatin (C6H14N2O4Pt) and Oxaliplatin (C8H14N2O4Pt) are the investigational chemotherapy medicines, belonging to platinum analogue interfere as the Cisplatin with the genetic …
Published in Research and Reviews: A Journal of Medicine · Vol. 5, Issue 3, 2015 · pp. 27–31 Read article
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Maternal and Fetal Consequences of Vitamin D Deficiency during Pregnancy: An Overview
Abstract: Apprehensions exist about the adequacy of vitamin D in pregnant and lactating women. Maternal vitamin D status influences maternal, fetal, and breast-fed infant bone health; maternal adverse outcomes (bone health, gestational diabetes, obstructed labor, preeclampsia, and infectious disease); fetal adverse outcomes (growth, bone health, gestational age, intrauterine growth, type 1 diabetes, asthma, immune development and cardiac disease); and infant adverse outcomes. Throughout pregnancy, maternal vitamin D standing may be of …
Published in Research and Reviews: A Journal of Medicine · Vol. 10, Issue 3, 2020 · pp. 12–28 Read article
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Auricular Acupuncture and Oral Administration of Hydrochlorothiazide Lowers Urine Output of Nephrogenic Diabetes Insipidus Patients Compared with Hydrochlorothiazide Monotherapy
Abstract: Context: There have been no investigations on auricular acupuncture for the treatment of nephrogenic diabetes insipidus (NDI). Aim: The aim of this study is to identify the clinical efficacy of auricular acupuncture plus hydrochlorothiazide for treating nephrogenic diabetes insipidus.Patients and Methods: Thirty-one patients with NDI were randomized into two groups: the AA (auricular acupuncture) group and the control group. Patients in the AA group received a true auricular acupuncture procedure …
Published in Research and Reviews: A Journal of Medicine · Vol. 12, Issue 3, 2022 · pp. 7–10 Read article