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1068 articles for “diseases”
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To Rule Out the Efficacy of Haridradi Drugs in Respiratory Allergic Disorders in the Childrens.
Abstract: Allergic diseases in children have increased significantly in recent years and they are a major cause of morbidity in the children. Although there is a genetic predisposition, exposure to allergens i.e pollens, irritants, infections, diets and inhalant will determine the sensitization. At present, the best approach to the children who are at high risk for the development of allergies is to introduce environmental and dietary control and adopt early measures …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 13, Issue 2, 2024 · pp. 53–60 Read article
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Aquatic Ecosystems: A Review on Prospecting of Anticancer Molecules from Fungi & Other Microbes
Abstract: Marine biota; namely, actinomycetes, bacteria, fungi, microalgae, green algae, oceanic weeds, mangroves, and other extremophiles constitute about 90% of the oceanic biomass. The organisms are taxonomically diverse, biologically productive/active, and biochemically unique. These unique biochemiques may act as a great source for the discovery of new bioactive molecules, including anticancer drugs. The marines produce medicinally potent biochemicals; namely, sulfated saccharides, polyphenols, and, sterols. Only a few of these alkaloids have …
Published in International Journal of Fungi · Vol. 1, Issue 2, 2024 · pp. 1–22 Read article
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Magnetic ZnxFe2–xO3 Nanoparticles Enhanced Nanobiosensor Integrated with MOSFETs for Efficient Detections of Biomolecules and Cancerous Cells
Abstract: The human brain is mostly responsible for intelligence and consciousness. An artificial equivalence of this action is nanobiosensor, which is used in artificial intelligence. The need for nanodiagnostics platforms for detecting diseases at the genetic, molecular, and cellular level has triggered the development of nanobiosensors integrated with MOSFETs. This device enables simple, inexpensive rapid tests, accurate imaging methods, and accurate molecular diagnosis at point-of-care (POC). This device is seen as …
Published in Journal of Nanoscience, NanoEngineering & Applications · Vol. 14, Issue 3, 2024 · pp. 33–44 Read article
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The Power of Genetic Engineering in Revolutionizing Vaccines
Abstract: Genetic engineering techniques, including recombinant subunit, viral vector, and nucleic acid vaccines have transformed the landscape of vaccine development. These novel approaches offer precise antigen design, enhanced safety profiles, and rapid adaptability to emerging pathogens. Key advantages include improved efficacy through targeted immune responses, increased safety due to the absence of live pathogens, and the ability to modify vaccines to address new variants or diseases quickly. Notable success stories, such …
Published in International Journal of Vaccines · Vol. 2, Issue 1, 2025 · pp. 18–27 Read article
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MicroRNAs in Animal Behavior: Regulation of Memory and Decision-Making in Mammals
Abstract: MicroRNAs are small, non-coding RNA molecules that play a crucial role in post-transcriptional regulation of gene expression. In recent years, their significance has extended beyond cellular development and disease regulation, as emerging evidence suggests they are critical mediators in complex behavioral processes, including learning, memory, and decision-making. This article explores the role of miRNAs in regulating neural plasticity and cognitive functions in mammals, emphasizing their involvement in memory formation and …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 13, Issue 3, 2024 · pp. 21–25 Read article
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Comprehensive Care in COPD: Integrating Non-Pharmacological Treatments in COPD
Abstract: The substantial worldwide respiratory disorder known as chronic obstructive pulmonary disease (COPD) calls for multifaceted care approaches in addition to medicines. The incorporation of alternatives to drugs into chronic pulmonary disease care is the main topic of this article, as it plays a crucial role in enhancing the lives of patients. Pulmonary rehabilitation, exercise training, nutritional support, psychological support, oxygen therapy, and surgical or interventional procedures are some of the …
Published in Research and Reviews: A Journal of Health Professions · Vol. 14, Issue 3, 2024 · pp. 12–18 Read article
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Utilizing circulation-derived cancer cells to evaluate patients with surgically treated stages I–IIIA NSCLC throughout the preoperative phase
Abstract: Context: When a tumor is considered resectable, surgery is viewed as the primary treatment approach for both early-stage and locally advanced non-small cell lung cancer (NSCLC). One of the most exciting areas of cancer research in the past ten years is liquid biopsy, which offers a practical non-invasive method for cancer detection and tracking. Circulating tumor cells (CTCs) have been linked to a worse prognosis and increased chance of relapse …
Published in Research and Reviews : Journal of Surgery · Vol. 13, Issue 3, 2024 · pp. 17–28 Read article
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Exploring the Therapeutic Potential of Phytohormones: Bridging Plant Immunity and Human Health
Abstract: This review highlights the multifaceted roles of phytohormones, including salicylic acid, abscisic acid, cytokinins, and brassinosteroids, emphasizing their contributions to plant immunity and potential therapeutic applications in human health. Phytohormones are critical regulators of plant growth, development, and defense, functioning as signaling molecules that activate and coordinate plant responses to biotic and abiotic stresses. Salicylic acid, in particular, is instrumental in systemic acquired resistance (SAR), a defense mechanism that strengthens …
Published in International Journal of Trends in Horticulture · Vol. 1, Issue 2, 2024 · pp. 20–23 Read article
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Exploring Azadirachta indica’s Potential to Combat Visceral Leishmaniasis Through GP63 Inhibition
Abstract: Objectives: Millions of people worldwide suffer from the parasite disease visceral leishmaniasis. Determine the naturally occurring active ingredients in Azadirachta indica, which are employed as a disease-prevention agent and have several uses in medicine. To choose the best ligand to use as a medication, absorption, distribution, metabolism, and excretion (ADME) studies and molecular docking are employed. Methods: To obtain the GP63 protein, the Protein Data Bank (PDB) database was accessed. …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 2, Issue 2, 2024 · pp. 1–12 Read article
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The Therapeutic Potential of Nutraceutical in Diabetes Management: A Comprehensive Review
Abstract: Diabetes is a long-term and complex condition characterized by high blood sugar levels resulting from inadequate insulin production, ineffective insulin function, or a combination of both. Various nutraceuticals used in clinical settings have shown beneficial impacts on a range of biochemical and clinical markers related to diabetes. In many traditional medical systems, hypoglycemic agents derived from plants are used to treat, manage, and prevent diabetes mellitus. These plant extracts have …
Published in Emerging Trends in Metabolites · Vol. 2, Issue 1, 2025 · pp. 20–27 Read article
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Efficacy Evaluation of Trichoderma Harzianum, T. Viride, & T. Asperellum: Eco-Biocontrol Agents Against Dry Rot of Potato in Pakistan
Abstract: Fusarium sambucinum is one of the most aggressive fusarium species initiating potato dry rot disease around the world and causing significant economic losses. To alleviate reliance on synthetic fungicides as their long-term use may lead to fungal resistance, biocontrol assays against threatening fungal diseases hold significant importance as an eco-friendly management approach. Antagonists are gradually becoming hotspots and hold broad applicable prospects. Trichoderma harzianum, T. viride, and T. asperellumwere screened …
Published in International Journal of Fungi · Vol. 2, Issue 1, 2025 · pp. 46–50 Read article
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Repurposing Approved Immunomodulatory Drugs for Target Proteins in the Pancreas of European eel: A Molecular Docking Approach
Abstract: Leishmaniasis is a disease caused by tiny parasites called Leishmania, which spread to humans through the bite of an infected female sand fly. The disease manifests in three different forms, and the protein calcitonin promotes the disease’s spread. By reducing blood calcium levels, inhibiting osteoclast activity, increasing calcium excretion, and possibly playing a role in neurotransmitter modulation, calcitonin, a hormone released by vertebrates, promotes the progression of pathogenesis and lessens …
Published in International Journal of Molecular Biotechnological Research · Vol. 3, Issue 1, 2025 · pp. 12–19 Read article
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Quinine: Past, Present, and Future Perspective in Malaria and Autoimmune Disorder
Abstract: Quinine, a natural alkaloid extracted from the bark of the cinchona tree, has traditionally played a key role in treating malaria, a disease caused by parasites of the Plasmodium genus. Since its discovery in the 17th century, quinine has evolved from a rudimentary treatment to an essential component of modern antimalarial therapies. This article explores the historical use of quinine in the fight against malaria, its role in current treatment …
Published in International Journal of Pathogens · Vol. 2, Issue 1, 2025 · pp. 24–33 Read article
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Abysmal Oddities of Brain in Neurological and Psychiatric Disorders Based on Sū’-i-Mizāj Māddῑ (Abnormal Substantial Temperament): Through The Lens of Greco-Arabic Medicine
Abstract: The mesmerizing history of neurological and psychiatric disorders relates to the history of humanity. The Unani philosophers apprehend neurological and psychiatric disorders superbly. They gave a conceptual understanding of the Sū’-i-Mizāj dimag and diagnosed neurological and psychiatric disorders wonderfully. Contrariwise, the Babylonians associated epilepsy, anxiety, depression, mania, and other psychiatric disorders with deities and demons earlier. To understand, analyse, and explain a comprehensive patho-physiology of neurological and psychiatric disorders, it …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 12, Issue 2, 2025 · pp. 30–42 Read article
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AI-Based Preventive Healthcare Using Quantum Computing
Abstract: With its improved performance and capabilities, quantum machine learning (QML) is becoming a promising field, especially in the healthcare industry for tasks like early heart disease prediction. In this work, a Quantum Support Vector Classifier (QSVC) is proposed as the basic classifier for a bagging ensemble learning model. Shapley Additive explanations (SHAP) are used to evaluate the significance of each attribute in the predictions in order to improve explainability. Using …
Published in Journal of Nanoscience, NanoEngineering & Applications · Vol. 15, Issue 2, 2025 Read article
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Role and impact of Dietary Antioxidants on Aging and Lifespan: A Review
Abstract: The effect of an antioxidant-rich diet on aging and lifespan has attracted significant scientific attention, primarily through the lens of the free radical theory of aging (FRTA). This theory suggests that oxidative stress caused by an accumulation of reactive oxygen species (ROS), accelerates aging and contributes to cellular damage. The accumulation of free radicals and the oxidative damage that is induced significantly contribute to the aging process. This imbalance plays …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 15, Issue 2, 2025 · pp. 60–70 Read article
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The Multifaceted Vitamin B6: Metabolism, Cardiovascular Health, Cognition, and Cancer
Abstract: Vitamin B6 is hydrophilic and plays a crucial role in various metabolic processes. It acts as a cofactor in different enzymatic reactions. Vitamin B6 exists in various forms, including pyridoxal 5'-phosphate (PLP), the most active form. Vitamin B6 is essential for amino acid metabolism, such as PLP is essential for transamination, the process of transferring amino groups between amino acids. This is vital for synthesizing non-essential amino acids and breaking …
Published in Research & Reviews : Journal of Food Science & Technology · Vol. 14, Issue 2, 2025 · pp. 33–39 Read article
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AI Application in the Creation of Medications for COPD
Abstract: The crippling lung condition known as chronic obstructive pulmonary disease (COPD) is typified by a continuous restriction of airflow, which results in increased respiratory dysfunction and a reduced quality of life. The rising incidence of COPD worldwide emphasizes the pressing need for innovative pharmaceutical approaches to address the illness. Even though COPD care has advanced significantly, most current medications concentrate on symptom relief rather than disease change. This gap in …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 2, 2025 · pp. 01–05 Read article
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Nano-Materials in Vaccine Formation and Chemical Formulae’s for Vaccination
Abstract: For centuries, vaccines have been a cornerstone of public health, preventing debilitating and deadly diseases. However, the development and delivery of effective vaccines have always been met with challenges. From stability issues and limited immune response to the need for specific targeting, scientists are constantly seeking innovative approaches to improve vaccine efficacy and accessibility. Enter nanomaterials – minuscule materials with dimensions at the nanoscale – offering a powerful toolkit to …
Published in Journal of Nanoscience, NanoEngineering & Applications · Vol. 15, Issue 3, 2025 · pp. 27–39 Read article
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Innovations in Targeted Drug Discovery for Personalized Medicine
Abstract: Personalized medicine is revolutionizing modern healthcare by custoizing treatment plans to match an individual’s genetic makeup, protein expression, and metabomlic characteristics. Also referred to as precision medicine, this approach seeks to improve therapeutic outcomes, reduce adverse effects, and make efficient use of healthcare resources. The incorporation of various omics technologies—including genomics, proteomics, transcriptomics, metabolomics, and epigenomics—has greatly advanced our ability to understand disease biology and molecular variations specific to each …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 3, 2025 · pp. 19–41 Read article