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632 articles for “Challenges” (ranking capped at the first 2,000 matches — narrow the search to see the rest)
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A Study to Evaluate the Impact of Health Education on Awareness of Long-term Complications of Hypertension Among Hypertensive Patients in A Selected Hospital, Bengaluru
Abstract: The rising burden of non-communicable diseases, particularly hypertension, poses significant public health challenges, especially in developing nations. This study aimed to assess the effectiveness of a health education program focused on lifestyle modifications to prevent hypertension-related complications among patients at selected hospitals in Bengaluru. Employing a quasi-experimental design, we recruited 60 hypertensive patients through purposive sampling. Initial knowledge was evaluated using a structured questionnaire, followed by an educational intervention provided …
Published in International Journal of Evidence Based Nursing And Practices · Vol. 2, Issue 2, 2024 · pp. 31–63 Read article
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A Comprehensive Review on Monkeypox Infection
Abstract: Monkeypox represents a zoonotic viral affliction instigated by the monkeypox virus, which is classified within the Poxviridae family and is distinct from the virus that causes chickenpox. Initially recognized in 1958, this infection has recently attracted international scrutiny due to its escalating incidence beyond traditional endemic territories. This review delivers an exhaustive examination of monkeypox, encompassing its epidemiology, viral morphology, modes of transmission, pathogenesis, clinical presentations, and therapeutic interventions. The …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 1, 2025 · pp. 23–32 Read article
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Gut Microbiome Dysbiosis During Metabolic Disorders: Diabetes
Abstract: Understanding the intricate interplay between gut microbiome dysbiosis and diabetes is crucial due to the escalating prevalence and impact of diabetes mellitus globally. This comprehensive review examines the current understanding of this relationship, elucidating how alterations in the gut microbiome composition contribute to diabetes pathogenesis by influencing metabolic homeostasis, immune regulation, and insulin resistance. Dysregulation of gut microbial communities leads to shifts in diversity and abundance, exacerbating chronic low-grade inflammation …
Published in Emerging Trends in Metabolites · Vol. 1, Issue 2, 2024 · pp. 56–75 Read article
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Flaxseed and Diabetes Management: A Comprehensive Review of Recent Studies and Potential Mechanisms
Abstract: Diabetes mellitus, a condition characterized by chronic hyperglycemia, has become a significant global health challenge, leading to substantial morbidity and mortality rates. Dietary techniques are crucial for the effective control of diabetes, including both pharmaceutical and non-pharmacological therapies. Flaxseed (Linum usitatissimum) is one of the functional foods that has attracted a lot of interest because of its abundance of bioactive components, including lignans, dietary fiber, and alpha-linolenic acid (ALA). The …
Published in International Journal of Nutritions · Vol. 2, Issue 1, 2025 · pp. 24–32 Read article
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Advancements in Molecular Engineering: Innovations at the Nexus of Chemistry and Technology
Abstract: Molecular engineering, a frontier of chemistry, merges precision and innovation to design and assemble molecular structures with unprecedented control. This abstract explores recent advances, highlighting key breakthroughs and their transformative impacts. Starting with its roots in chemical synthesis and materials science, it traces the evolution towards rational design driven by computational tools and advanced characterization techniques, enabling tailored molecular architectures. A focal point is programmable molecules, where DNA nanotechnology principles …
Published in International Journal of Advance in Molecular Engineering · Vol. 1, Issue 2, 2023 · pp. 37–43 Read article
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Advanced Computational Models for Predicting Molecular Interactions
Abstract: Understanding molecular interactions is essential for a number of disciplines, including biochemistry, materials science, and medication development. Traditional experimental methods, while accurate, are often time-consuming and expensive. Advanced computational models have emerged as powerful tools to predict molecular interactions efficiently. In order to predict the behavior and interactions of molecules at the atomic and subatomic levels, this paper reviews the most recent developments in computational techniques, such as machine learning …
Published in International Journal of Advance in Molecular Engineering · Vol. 2, Issue 1, 2024 · pp. 8–13 Read article
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Discourse of Self and Other in Landscape by Harold Pinter
Abstract: This paper explores Harold Pinter’s Landscape as a pivotal representation of the complex dynamics between the subjective self and social reality. It investigates how the characters' introspection blurs the line between objective and subjective truths, highlighting their disillusionment with present-day existence and their reliance on past memories for solace. Through a dialectic discourse, Pinter’s characters reconstruct their identities and relationships, presenting fragmented versions of truth that reveal the unreliability of …
Published in Emerging Trends in Languages · Vol. 2, Issue 1, 2025 · pp. 10–17 Read article
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Ants in Ecosystems and Agriculture: A Comprehensive Review
Abstract: Nearly 60% of the world’s habitats are underutilized. And current agricultural practices are blamed for contributing to soil carbon depletion and biodiversity loss. Climate change, habitat fragmentation, and other challenges hinder species development, leading to projected shifts in species distribution. This calls for alternative management strategies. The organizational structure of social insects, especially ants, offers a model for improved ants account for half of all insect biomass. It plays an …
Published in International Journal of Insects · Vol. 1, Issue 2, 2024 · pp. 15–22 Read article
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Preserving Saccharomyces cerevisiae Culture for Bee Health and Production
Abstract: Saccharomyces cerevisiae, a single-celled fungus also known as baker’s and brewer’s yeast, is extensively used in brewing, baking, and winemaking due to its robust genetics and utility as a model organism in scientific research. Its role extends beyond these applications into apiculture, where it is utilized to produce supplements and pollen replacements for honeybees. These yeast-based supplements are crucial, especially during times of pollen scarcity or colony stress, as they …
Published in International Journal of Insects · Vol. 1, Issue 2, 2024 · pp. 23–27 Read article
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Super Built-Up Area: Examining Its Role in Real Estate Development and Urban Planning Strategies
Abstract: The concept of Super Built-Up Area (SBA) has become pivotal in contemporary real estate development and urban planning strategies. Defined as the total area encompassing the built-up area of an apartment along with common areas like corridors, staircases, and amenities shared among residents, SBA influences both the economic viability of real estate projects and the spatial dynamics of urban landscapes. This study investigates the multifaceted role of SBA in shaping …
Published in International Journal of Urban Design and Development · Vol. 2, Issue 2, 2024 · pp. 01–15 Read article
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Evaluation of Polysaccharide-Based Membranes for Transdermal Drug Delivery in Chronic Pain Management
Abstract: In order to improve treatment effectiveness and patient compliance, chronic pain management is still a major challenge in modern healthcare, requiring creative medication delivery methods. The potential of polysaccharide-based membranes for transdermal drug delivery is assessed in this work, with particular attention to chitosan, alginate, and hydroxypropyl methylcellulose (HPMC). Fourier-transform infrared spectroscopy (FTIR) and scanning electron microscopy (SEM) were two characterization techniques used to assess the membranes' physical and chemical …
Published in International Journal of Membranes · Vol. 1, Issue 2, 2024 · pp. 28–38 Read article
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Development of a Novel Therapeutic Approach Using RNA Interference for Targeting Viral Genes
Abstract: RNA interference (RNAi) is a ground breaking therapeutic strategy that holds immense promise for targeting viral genes in the treatment of viral infections. This approach leverages the natural gene-silencing mechanisms of RNAi to inhibit viral replication and expression at the molecular level, providing a precise and adaptable method to counteract viral pathogens, including influenza, HIV, and hepatitis viruses. Recent advancements in RNAi technology have enabled the development of highly specific …
Published in International Journal of Virus Studies · Vol. 1, Issue 2, 2024 · pp. 12–22 Read article
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The Role of Natural Products in Antiviral Drug Discovery: Insights into Mechanisms and Therapeutic Potential
Abstract: Drug discovery has always relied heavily on natural sources, especially when it comes to creating antiviral medications. This review explores the therapeutic potential of various natural products, including plant extracts, marine compounds, and microbial metabolites, in the fight against viral infections. We examine the mechanisms of action by which these natural compounds exert their antiviral effects, including direct inhibition of viral replication, modulation of host immune responses, and interference with …
Published in International Journal of Virus Studies · Vol. 1, Issue 2, 2024 · pp. 36–47 Read article
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Investigating the Impact of Viral Infections on Pharmacokinetics and Pharmacodynamics of Antiviral Drugs
Abstract: The emergence and re-emergence of viral infections pose significant challenges to public health, necessitating a comprehensive understanding of how these infections impact the pharmacokinetics and pharmacodynamics of antiviral drugs. This review explores the intricate interactions between viral pathophysiology and the pharmacological effects of antiviral agents. Factors such as viral replication dynamics, host immune responses, and the genetic variability of both viruses and hosts significantly influence drug absorption, distribution, metabolism, and …
Published in International Journal of Virus Studies · Vol. 1, Issue 2, 2024 · pp. 23–30 Read article
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Innovative Porcelain Insulators: Prolonged Durability and Anti-Contamination Efficiency via Nano-TiO2 Photocatalyst Integration
Abstract: Porcelain has long been a critical material in high-voltage electrical insulation due to its exceptional mechanical, thermal, and dielectric properties. However, environmental contamination and material degradation over time pose significant challenges to its durability. This study investigates the integration of nano-sized titanium dioxide (TiO2) photocatalyst coatings on porcelain insulators to enhance their performance and prolong their operational lifespan. Local clay compositions were analyzed, and a comparative study of untreated and …
Published in International Journal of Crystalline Materials · Vol. 1, Issue 2, 2024 · pp. 18–23 Read article
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Advances in Polymeric In Situ Drug Delivery and Soft Biosensors: Innovations in Biochemical Sensing and Personalized Healthcare
Abstract: Advanced healthcare and personalized medicine are undergoing a transformation thanks to in situ medication delivery systems and biochemical sensor technology. Polymeric in situ drug delivery systems form gels upon administration, releasing medications in a controlled manner and providing benefits such as ease of administration and enhanced patient compliance. Similarly, advancements in soft electronics, including flexible and stretchable biosensors, enable continuous, in situ biochemical monitoring, conforming to complex biological environments like …
Published in International Journal of Cheminformatics · Vol. 2, Issue 1, 2024 · pp. 27–32 Read article
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Toward Comprehensive Immunization: The Role of Combined COVID-19 and Influenza Vaccines in Public Health
Abstract: The emergence of multi-pathogen vaccines, particularly those combining protection against COVID- 19 and influenza, marks a significant advancement in immunization efforts. These combination vaccines have the potential to streamline vaccination processes, improve vaccine uptake, and reduce the burden on healthcare systems by offering a single dose that targets both viruses. COVID-19 and seasonal influenza are major public health concerns, with overlapping symptoms and seasonal patterns that justify the rationale for …
Published in International Journal of Vaccines · Vol. 2, Issue 1, 2025 · pp. 9–17 Read article
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Decompensated Liver Failure and Acute Renal Failure in a Patient with Chronic HBV,HCV, and HIV Infections
Abstract: This case study focuses on a 30-year-old male patient suffering from decompensated liver failure and acute renal failure, complicated by chronic hepatitis B (HBV), hepatitis C (HCV), and HIV/AIDS. Presenting with severe abdominal pain, nausea, and general weakness, the patient had a history of alcohol and intravenous drug use, leading to chronic liver disease and acute renal failure. Despite aggressive interventions, including intravenous antibiotics and fluid therapy, his condition worsened …
Published in International Journal of Pathogens · Vol. 2, Issue 1, 2025 · pp. 17–23 Read article
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Complex Tuberculous Meningitis: A Case Series Highlighting Rare Co-infections and Severe Complications
Abstract: This case series presents two complex cases of tuberculous meningitis (TBM) with different complications, illustrating the diverse clinical presentations and management challenges of this disease. Case 1 involves an 18-year-old female with TBM complicated by cryptococcal co-infection, while Case 2 describes a 64-year-old female with TBM complicated by obstructive hydrocephalus and secondary bacterial infections. Both patients had been on anti-tubercular therapy before presentation. Diagnostic approaches included cerebrospinal fluid analysis, cultures, …
Published in International Journal of Pathogens · Vol. 1, Issue 2, 2024 · pp. 1–7 Read article
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Malaria Diagnosis through Conventional Methods: A Comprehensive Review
Abstract: The incidence of drug-resistant parasite strains is rising, there is an apparent increase in the number of cases of malaria worldwide, and in a small number of cases and there has been a dramatic rise in international migration and travel. Over 1 million people die from malaria every year; 90% of these deaths are in African children, who live in tropical and subtropical regions. Although there are now efficient techniques …
Published in International Journal of Pathogens · Vol. 1, Issue 2, 2024 · pp. 8–14 Read article