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31 articles for “survival strategies”
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IoT-based Heart Attack Prediction System Using Machine Learning
Abstract: Heart disease, particularly heart attacks, is one of the leading causes of mortality worldwide. Timely detection and prompt intervention play a vital role in significantly improving the survival rates of individuals at risk of cardiac events. Unfortunately, most traditional healthcare systems are not equipped with mechanisms for continuous, real-time monitoring of patients' cardiovascular health. This limitation makes it extremely difficult for healthcare providers to identify warning signs early enough to …
Published in Journal of Telecommunication, Switching Systems and Networks · Vol. 12, Issue 2, 2025 · pp. 1–5 Read article
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Efficacy of Combination Therapy with Osimertinib and Afatinib in epidermal growth factor receptor-mutant non-small-cell lung cancer Patients
Abstract: Treatment options for patients with non-small-cell lung cancer who have epidermal growth factor receptor mutations are constrained by the emergence of resistance to epidermal growth factor receptor tyrosine kinase inhibitors. Osimertinib or afatinib alone, when tested in a laboratory model, led to the formation of drug-resistant clones harboring epidermal growth factor receptor secondary mutations. However, combining these drugs prevented the emergence of such mutations. In a Phase II clinical trial, …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 13, Issue 1, 2024 · pp. 13–24 Read article
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Precision Medicine Approaches for Cancer Therapy Recent and Advance
Abstract: Recent advances in biotechnology have made it possible to identify intricate and distinctive biological characteristics linked to carcinogenesis. Proteomic and RNA studies, immunological markers, tumor and cell-free DNA profiling, and other methods are utilized to find these traits in order to optimize anticancer treatment for specific patients. In recent years, the focus of clinical trials has shifted considerably to enhance treatment outcomes in cancer therapy. Rather than being primarily centered …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 14, Issue 1, 2025 · pp. 1–11 Read article
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Host Invasion to Immune Evasion: Emerging Concepts in Pathogen Virulence Strategies
Abstract: Pathogens have evolved a wide repertoire of virulence strategies that allow them to invade host tissues, establish infection, and circumvent immune responses. From the initial steps of adhesion and colonization to complex molecular mimicry, antigenic variation, and immunomodulation, pathogens display remarkable adaptability. While traditional research has emphasized host cell entry and toxin production, emerging evidence highlights subtler and more dynamic strategies such as manipulation of host signaling pathways, subversion of …
Published in International Journal of Pathogens · Vol. 2, Issue 2, 2025 Read article
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Knowledge, Attitude, and Practice Regarding Breast Cancer and Its Prevention Among Adolescent School-Going Girls
Abstract: Introduction: Breast cancer claims the lives of over 500,000 women globally each year. In low-resource settings, most women are diagnosed at an advanced stage of the disease, resulting in low 5-year survival rates, typically ranging between 10 and 40%. However, in regions where early detection and basic treatment are both available and accessible, the 5-year survival rate for early-stage localized breast cancer can exceed 80%. Objectives of the Study: The …
Published in International Journal of Community Health Nursing And Practices · Vol. 3, Issue 2, 2025 · pp. 1–9 Read article
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Atmospheric Determinants of Feed, Fodder, and Forage Contamination in a Changing Climate: Emerging Challenges for Sustainable Livestock Production
Abstract: Feed, fodder, and forage contamination represents a growing constraint to sustainable livestock production under a changing climate. Atmospheric determinants such as rising temperature, altered precipitation patterns, increased humidity, elevated carbon dioxide concentration, and enhanced aerosol and pollutant loads are increasingly recognized as critical drivers of contamination risks across feed supply chains. These atmospheric factors directly and indirectly influence crop growth, fungal proliferation, mycotoxin biosynthesis, microbial survival, and the deposition of …
Published in International Journal of Atmosphere · Vol. 3, Issue 1, 2026 · pp. 1–14 Read article
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Tools and Techniques of Green Manufacturing and FMS for Advanced Automation
Abstract: Industrialization has become a thriving key concern in the present serious world. The organizations are endeavoring hard to continue to survive for themselves. Henceforth are giving better products with quality, customer satisfaction and benefits and are improving their assembling activities in the present remarkable worldwide rivalry. On the other hand, the assembling area devours parcel of energy and different assets leading to discharge of enormous measures of ozone harming substances …
Published in Trends in Mechanical Engineering & Technology Read article
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Assessing the impact of lifestyle factors on autoimmune risk and survival outcomes: A Population-based Study
Abstract: This study investigated the interplay between lifestyle factors and genetic regulation in autoimmune diseases, focusing on the role of human T-cell metabolic and proliferative control through C-REL gene transcription. This study combined CRISPR-Cas9 manipulation of C-REL in human T-cells with a longitudinal cohort of 100 adults (autoimmune patients and controls), investigating metabolic and proliferation dynamics via flow cytometry and assays. It assessed lifestyle impacts through surveys and medical records, ensuring …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 15, Issue 2, 2025 Read article
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Cellular Mechanisms of Autophagy in Carcinogenesis: A Narrative Review
Abstract: Autophagy is a highly conserved lysosomal degradation pathway essential for cellular homeostasis, metabolic adaptation, and survival under stress. In the context of carcinogenesis, autophagy exhibits a paradoxical and stage-dependent role. During early tumor development, autophagy acts as a tumor-suppressive mechanism by limiting genomic instability, oxidative stress, and chronic inflammation. Conversely, in established malignancies, cancer cells exploit autophagy to sustain growth, survive hostile tumor microenvironments, and resist anticancer therapies. Increasing evidence …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 15, Issue 1, 2026 · pp. 23–28 Read article
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Targeting Vasopressin 2 Receptor (V2R) in Renal Cystogenesis by Exploring the Nephroprotective Potential of “Terminalia arjuna”
Abstract: Objectives: Autosomal dominant polycystic kidney disease (ADPKD) is the most common inherited kidney disorder, leading to the formation of multiple cysts in the kidneys. It is a major cause of end-stage renal disease (ESRD), which often requires dialysis or a kidney transplant for survival. This research focuses on identifying potential bioactive compounds derived from natural sources that show promise for drug development targeting the V2R gene. Methods: The naturally occurred …
Published in Research and Reviews : Journal of Computational Biology · Vol. 13, Issue 2, 2024 · pp. 14–24 Read article
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Universal Immunization Program in India
Abstract: The Universal Immunization Program (UIP) in India, initiated by the Government of India in 1985 and incorporated into the Child Survival and Safe Motherhood Program in 1992, plays a crucial role in enhancing public health through systematic vaccination efforts. This program aims to save lives and strengthen immune systems by administering vaccines and antibiotics. The UIP has spurred the development of various campaigns, including mass media efforts, to promote immunization …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 14, Issue 2, 2024 · pp. 24–30 Read article