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30 articles for “homeostasis”
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Post-Antibiotic Gut Microbiota Recovery in the Rumen: Insights into Colonization Patterns, Population Density, and Diversity Dynamics
Abstract: The post-antibiotic recovery of gut microbiota represents a critical area of research in understanding how microbial communities rebalance and re-establish homeostasis following antibiotic-induced disruptions. Antibiotics, while effective against infections, can cause substantial shifts in gut microbiota, leading to dysbiosis – a state of microbial imbalance that impairs gut health and functions. This recovery process involves multiple complex dynamics, including colonization patterns, population density, and the restoration of microbial diversity. The …
Published in International Journal of Antibiotics · Vol. 2, Issue 2, 2025 · pp. 1–17 Read article
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Histological Effects of the Antibiotic Gentamicin on the Ovarian Tissue of Female White Laboratory Rats
Abstract: This study aimed to evaluate the histological alterations induced by Gentamicin in the ovarian tissue of white laboratory rats. A total of 12 adult female rats were used and randomly divided into two groups, with each group consisting of six animals. The experimental group received Gentamicin at a dose of 120 mg/kg body weight administered as an injection once daily, while the control group received an equivalent volume of normal …
Published in International Journal of Antibiotics · Vol. 3, Issue 1, 2026 · pp. 1–8 Read article
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Biological Membranes: Structure, Function, and Their Roles in Disease Pathophysiology
Abstract: Biological membranes are important structures that control cellular work, signal transmission, transport, and communication. Dysfunction of membranes has been considered in the development of many diseases, such as cancer, neurodegenerative diseases, and infections, with the distortion of lipid composition, protein activity, and cellular connections involved in the pathogenesis of the disease. The damage on membrane can be caused by oxidative stress, genetic mutation, and environmental influence to disrupt cellular homeostasis. …
Published in International Journal of Membranes · Vol. 3, Issue 1, 2026 · pp. 38–46 Read article
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Cellular Mechanisms of Autophagy in Carcinogenesis: A Narrative Review
Abstract: Autophagy is a highly conserved lysosomal degradation pathway essential for cellular homeostasis, metabolic adaptation, and survival under stress. In the context of carcinogenesis, autophagy exhibits a paradoxical and stage-dependent role. During early tumor development, autophagy acts as a tumor-suppressive mechanism by limiting genomic instability, oxidative stress, and chronic inflammation. Conversely, in established malignancies, cancer cells exploit autophagy to sustain growth, survive hostile tumor microenvironments, and resist anticancer therapies. Increasing evidence …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 15, Issue 1, 2026 · pp. 23–28 Read article
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Clinical metabolomics: Useful insights, perspectives, and challenges.
Abstract: Metabolomics provides a comprehensive snapshot of smallmolecule intermediates and end products of cellular processes and thereby links genotype, environment, and phenotype in human disease . Over the last decade, advances in liquid chromatography–mass spectrometry (LC–MS) and nuclear magnetic resonance (NMR) spectroscopy have enabled high-throughput profiling of thousands of metabolites from microliter volumes of clinical samples . Clinical metabolomics is now emerging as a tool for disease diagnosis, risk prediction, therapeutic …
Published in Emerging Trends in Metabolites · Vol. 3, Issue 1, 2026 · pp. 29–37 Read article
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Gut Microbial Metabolites in Inflammatory, Metabolic, and Neurologic Disorders.
Abstract: The human gut microbiota transforms dietary and hostderived substrates into a diverse array of metabolites—including shortchain fatty acids (SCFAs), hydrogen sulfide (H₂S), bile acid derivatives, indoles, trimethylamine Noxide (TMAO), branchedchain amino acid (BCAA) derivatives, and lipopolysaccharide (LPS)—that act as key signaling mediators along epithelial, immune, endocrine, and neural axes. These metabolites regulate barrier integrity, energy homeostasis, inflammation, and gut–brain communication and are increasingly implicated in the pathogenesis of inflammatory bowel …
Published in Emerging Trends in Metabolites · Vol. 3, Issue 1, 2026 · pp. 58–64 Read article
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Plant Bioactive Metabolites and Their Role in the Prevention and Control of Dental Diseases and Infections.
Abstract: The oral diseases, including dental caries and periodontitis, affect masses worldwide, and have historically been managed with synthetic antimicrobials that cause deleterious side effects, leading to mounting bacterial resistance. Consequently, contemporary dentistry is rapidly shifting toward phytomedicine using plant bioactive molecules, such as polyphenols, terpenes, anthraquinones (berberin, eugenol, curcumin, catechins, allicin, and azadirachtin. These compounds offer potent antimicrobial, anti-inflammatory, and tissue-regenerative properties that are crucial for preventing and curing dental …
Published in Emerging Trends in Metabolites · Vol. 3, Issue 1, 2026 · pp. 47–66 Read article
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Biopolymer Degradation and Structure–Property Relationships in Ageing: A Polymer Science Perspective
Abstract: Ageing, as viewed from the polymer sciences perspective, is perceived as the gradual modification of the structure-property-function interrelationship of biopolymers such as proteins, polysaccharides, nucleic acids and their molecular aggregates. Such changes include structural organization, mechanical behavior, physicochemical stability and functional effectiveness. Ageing is an inevitable multifactorial polymeric process. Due to the growing aging population globally, more age-associated complications emerge, which are correlated with the molecular degeneration of biopolymeric complexes. …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 479–489 Read article
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Rumen Microbial Adaptation to Dietary Shifts: Mechanisms, Challenges, and Implications for Sustainable Ruminant Production
Abstract: Rumen microbiota play a central role in the digestion and fermentation of dietary components, directly influencing the health and productivity of ruminants. Dietary shifts, such as transitioning from forage-based diets to concentrate-rich diets or incorporating feed additives, induce significant changes in the composition, structure, and functional dynamics of the rumen microbial community. These adaptations, while essential for maintaining microbial homeostasis, can also lead to transient imbalances, including risks of acidosis, …
Published in Research & Reviews : Journal of Ecology · Vol. 15, Issue 1, 2026 · pp. 17–26 Read article
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Crop Metabolism: A Biochemical Perspective on the Synthesis of Key Biomolecules and Structural Adaptations
Abstract: Crop metabolism involves intricate biochemical pathways that govern the biosynthesis of essential biomolecules, ensuring growth, development, and adaptability in various environmental conditions. Key processes include the synthesis of nucleic acids, amino acids, proteins, carbohydrates, organic acids, lipids, and natural products, each playing vital roles in maintaining cellular homeostasis. Nucleic acids drive genetic information storage and transfer, while amino acids and proteins form the backbone of enzymatic and structural cellular functions. …
Published in Research and Reviews : Journal of Crop science and Technology · Vol. 14, Issue 1, 2025 · pp. 26–31 Read article