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27 articles for “conjugation”
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Formulation Challenges in Long-acting Injectable Small Molecules: Emerging Strategies and Perspectives
Abstract: Long-acting injectable (LAI) formulations represent a transformative approach in pharmacotherapy, particularly for conditions demanding sustained drug exposure over weeks to months. Although biologics have dominated this space historically, the adaptation of LAI technology to small molecules presents a distinct and complex set of challenges rooted in physicochemical properties, manufacturing scalability, and regulatory expectations. This review systematically addresses the principal formulation barriers encountered in developing LAI small-molecule products, including aqueous solubility …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 13, Issue 2, 2026 Read article
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Study of Electrically Conductive Polymer for Antistatic and Sensor Application
Abstract: Electrically conductive polymers (ECPs) are a unique category of smart materials that integrate the mechanical flexibility and ease of processing characteristic of conventional polymers with the electrical conductivity typically associated with metals or semiconductors. In recent years, they have attracted considerable interest due to their promising potential in advanced technological applications, especially in antistatic coatings and electronic sensing devices. The unique ability of these polymers to conduct electricity arises from …
Published in International Journal of Minerals · Vol. 3, Issue 1, 2026 · pp. 46–51 Read article
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Zero-Concentrate Feeding in Dairy Cows: A Sustainable Approach to Milk Quality, Animal Health, and Welfare
Abstract: The study explores the benefits of eliminating concentrate feeds in dairy cow nutrition. As sustainability becomes a central concern in agriculture, zero-concentrate feeding offers a promising solution to reduce the environmental footprint of dairy farming while promoting optimal animal health and welfare. This approach primarily focuses on maximizing the use of high-quality forages, such as grasses and legumes, to meet the nutritional needs of dairy cows. By minimizing the use …
Published in Research and Reviews : Journal of Dairy Science and Technology · Vol. 15, Issue 1, 2026 · pp. 30–47 Read article
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Biopolymer-Based 3D Composite Scaffolds for Bone Tissue Engineering: Photothermal-Responsive Systems with Controlled Pt (IV) Prodrug Release
Abstract: Biopolymer-based composite scaffolds have attracted significant attention as multifunctional platforms at the intersection of polymer science, regenerative medicine, and cancer nanotherapy. In this study, a dual-functional scaffold was developed for simultaneous osteosarcoma treatment and bone regeneration using poly (L-lactic acid) (PLLA) reinforced with bioactive glass (BG) and integrated with a glutathione-responsive platinum (IV) prodrug system (PDA@Pt). To improve interfacial adhesion, photothermal conversion efficiency, and tumor-specific activation, the Pt (IV) prodrug …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 351–361 Read article
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Thermo-hydraulic Performance of Annular-Finned Double-Pipe Heat Exchanger: Numerical and Experimental Investigation of Metallic and Polymer Composite Tube Wall Materials
Abstract: Double-pipe heat exchangers are central to the process industries — dependable, easily maintained, and straightforward to fabricate. Their conventional form relies on metallic tube materials, most often copper or stainless steel. Both metals conduct heat well, but they are dense, prone to corrosion in aggressive service environments, and increasingly at odds with the light-weighting goals that drive modern system design. Fibre-reinforced polymer composites, epoxy-based materials, and thermally enhanced thermoplastics such …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 891–909 Read article
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An Investigation on Influence of Gamma Irradiation and Doping on Chemical Structure and Optical Properties of Conducting Polypyrrole
Abstract: In this study the authors report on effect of gamma irradiation and doping (bromine, iodine and sulfate ion) on chemical structure and optical, electronic properties of poly pyrrole. Optical absorption spectrum of PPY shown absorption bands centered around 36.2.5nm (peak 1), 450 nm (peak2) and 525 nm (peak 3) positions Gamma irradiation resulted in broaden of peak A together with a band shift of 45- 525 nm and disappearance peaks …
Published in Journal of Polymer & Composites · Vol. 14, Issue 5, 2026 Read article
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In-Situ Polymerized GO/PANI Composites: Structural Evolution, Optical Modulation, and NH₃ Sensing at Room Temperature
Abstract: Graphene oxide (GO)/polyaniline (PANI) composites with varying PANI contents (20, 40, and 60 wt%) were synthesized via in-situ oxidative polymerization and systematically investigated for their structural, morphological, optical, and gas-sensing properties. X-ray diffraction (XRD) confirmed a progressive increase in interlayer spacing and partial exfoliation of GO layers with increasing PANI content, indicating intercalation-assisted hybridization. Fourier transform infrared (FTIR) spectroscopy revealed the characteristic vibrational bands of both constituents and confirmed strong …
Published in Journal of Polymer & Composites · Vol. 14, Issue 4, 2026 Read article