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28 articles for “comorbidity”
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Combining Unstructured and Structured Clinical Data in a Hybrid Transformer Model to Enhance Cardiovascular Analytics and Clinical Decision- Making
Abstract: Since cardiovascular disease (CVD) continues to be a major global cause of morbidity and mortality, early and accurate risk prediction is essential for prompt intervention and individualized treatment. This study introduces a new hybrid transformer-based model that combines unstructured clinical narratives, structured data, and customized lifestyle characteristics. A comprehensive understanding of disease progression is made possible by the model's ability to capture contextual, temporal, and patient- specific insights through the …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 4, Issue 1, 2026 · pp. 30–37 Read article
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Clinical Medicine Done with Clinical Accuracy
Abstract: The advancement of clinical medicine has progressively underscored the significance of accuracy in diagnosis and therapy. This article examines the concept of "Clinical Medicine Administered with Clinical Precision," emphasising how innovations in diagnostics, data analytics, and personalised treatments are transforming the healthcare environment. Clinicians can provide therapy that is not only successful but also personalised to each patient's requirements by combining evidence-based practices with patient-specific factors including genetic profiles, comorbidities, …
Published in Emerging Trends in Personalized Medicines · Vol. 3, Issue 1, 2026 · pp. 6–19 Read article
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Paediatric Epilepsy: Current Advances in Diagnosis and Management
Abstract: Paediatric epilepsy is one of the most common chronic neurological disorders of childhood, characterised by recurrent unprovoked seizures resulting from abnormal neuronal activity. Accurate diagnosis is essential and is based on a detailed clinical history, seizure semiology, neurological examination, and electroencephalography (EEG), with neuroimaging such as magnetic resonance imaging (MRI) used to identify structural abnormalities. Classification according to seizure type and underlying aetiology genetic, structural, metabolic, immune, infectious, or unknown—guides …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 1, 2026 · pp. 53–68 Read article
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Systolic-Predominant Hypertension and the Aging Heart: A Cross-Sectional Study on LVH and Cardiovascular Riskss
Abstract: Background: Systolic-predominant hypertension, defined as a systolic blood pressure ≥140 mm Hg with diastolic pressure <90 mm Hg, is the most prevalent form of hypertension in the elderly. It arises primarily due to age-related arterial stiffening and baroreceptor dysfunction. Once considered a benign outcome of aging, systolic-predominant hypertension is now recognized as a major risk factor for cardiovascular morbidity and mortality. Aim and Objective: To evaluate the cardiac status and …
Published in Research and Reviews: A Journal of Medicine · Vol. 16, Issue 1, 2026 · pp. 13–24 Read article
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Demodex spp. (Acari: Demodicidae) Infestation in Humans: Diagnostic Clues and Therapeutic Approaches to Primary and Secondary Demodicosis.
Abstract: Demodicosis represents an inflammatory dermatosis and adnexal disorder arising from pathologic overgrowth of Demodex mites, primarily Demodex folliculorum and Demodex brevis, which are ubiquitous human ectoparasites residing in pilosebaceous units and eyelid margins. Once regarded as benign commensals, these mites are now recognized as primary drivers or key cofactors in diverse clinical phenotypes, including papulopustular eruptions, pityriasis folliculorum, rosacea-like disorders, blepharitis, meibomian gland dysfunction, and exacerbations of comorbid dermatoses such …
Published in International Journal of Insects · Vol. 3, Issue 1, 2026 · pp. 12–20 Read article
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A Study to Assess the Risk Factors Associated with Sudden Death in Population on Hemodialysis
Abstract: Background: Patients with chronic kidney disease (CKD) receiving maintenance hemodialysis (HD) experience disproportionately high mortality, with sudden death remaining a leading cause. Multiple clinical, biochemical, and care-related factors influence outcomes, yet comprehensive risk stratification models and the role of dialysis timing and early nephrology care remain inadequately explored in resource-limited settings. Objectives: This study aimed to (i) identify clinical and biochemical risk factors associated with mortality in HD patients, (ii) …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 16, Issue 1, 2026 · pp. 14–19 Read article
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The Evolution of Asthma Management: A Comprehensive Analysis of GINA 2024 Guidelines, Endotype-Driven Diagnosis, and Targeted Biologic Intervention
Abstract: Asthma remains a substantial global public health challenge, characterized by heterogeneous airway inflammation leading to variable airflow obstruction. Recent advances in personalized medicine and guideline revisions, notably the Global Initiative for Asthma (GINA) 2024 update, mandate a profound paradigm shift from reliance on short-acting beta2-agonists (SABA) to antiinflammatory reliever (AIR) strategies utilizing inhaled corticosteroid (ICS)-formoterol. This report provides an exhaustive analysis of current asthma epidemiology, molecular pathogenesis distinguishing between Type …
Published in Recent Trends in Infectious Diseases · Vol. 3, Issue 2, 2026 Read article
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The Burden of Empirical Therapy: Analyzing the Predominance of Broad-Spectrum Antibiotic Usage in Lower Respiratory Tract Infections
Abstract: Lower respiratory tract infections (LRTIs) remain one of the leading causes of morbidity and hospitalization worldwide, particularly among older adults, immunocompromised individuals, and patients with chronic respiratory disorders. These infections include conditions such as community-acquired pneumonia, hospital-acquired pneumonia, bronchitis, and acute infective exacerbations of chronic lung disease, all of which often require rapid clinical intervention. Because microbiological confirmation of the causative pathogen frequently takes 48–72 hours, clinicians generally initiate empirical …
Published in International Journal of Antibiotics · Vol. 3, Issue 2, 2026 Read article