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28 articles for “clinically approved medications”
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Formulation And Evaluation of Vyadhikshamatva Vardhak Giloy Ghanvatis
Abstract: The product of Kalka Kalpana, one of the five essential ayurvedic medicinal preparations, is vati Kalpana. Because of its many advantages, such as its tasty nature, ease of administration, ease of dispensing, and ease of transportation, vati kalpana is a vital part of the ayurvedic formulation. A pharmaceutical technique called vati kalpana uses powder of unprocessed medications (herbal or herbo minerals) and is triturated using juice, honey, or kassayam, and …
Published in Research & Reviews : Journal of Herbal Science · Vol. 13, Issue 2, 2024 · pp. 7–13 Read article
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Clinical Trial to Find the (Asbab) Aetiology and (Ilaj) Treatment of (Marz-e-Akyās Khusyat-ur-Rahim) Polycystic Ovarian Syndrome (PCOS)
Abstract: Introduction: Polycystic Ovarian Syndrome (PCOS) is common endocrine disorder. It is clinically defined as the syndrome characterized by amenorrhoea, hirsutism and obesity associated with polycystic ovaries. Diagnosis is made on the Rotterdam criteria, established in 2003. The criteria require the presence of 2 of the following 3 criteria: 1. Oligo-ovulation or an ovulation. 2. Hyperandrogenism. 3. Polycystic ovaries through ultrasound evaluation. Methods: Diagnosed patients were enrolled in the trial into …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 12, Issue 3, 2025 · pp. 30–37 Read article
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Comprehensive Approaches to Understanding and Managing Alzheimer’s Disease
Abstract: Alzheimer’s disease is an advanced neurodegenerative disorder described by intense memory loss. It strictly affects the patient’s quality life. The popularity of AD has been increasing in recent years. It is the most common form of mental disorder affecting more than 20 million people in the world. The Alzheimer’s disease is treated with cholinesterase inhibitors or NMDA-receptor (N-methyl D-aspartate) antagonists but here the question is about the therapeutic effect of …
Published in International Journal of Tropical Medicines · Vol. 2, Issue 1, 2025 · pp. 1–9 Read article
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Evaluating Linezolid: A Comprehensive Analysis
Abstract: Treatments for infections caused by Gram-positive bacteria, such as methicillin-resistant staphylococci and VRE, including skin and soft tissue infections, community-acquired pneumonia, and other infections treated with linezolid, an oxazolidinone antimicrobial agent that functions by specifically inhibiting protein synthesis. Even while antibiotic resistance is becoming more frequent in many nations, linezolid resistance among these pathogens is still low, typically less than 1%. Thus, the emergence of resistance in clinical isolates should …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 11, Issue 2, 2024 · pp. 11–16 Read article
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Computational Investigation of Phytochemicals Targeting AKT1 for Major Depressive Disorder: A Molecular Docking and ADMET Study
Abstract: Major depressive disorder (MDD) is a prevalent neuropsychiatric condition affecting approximately 280 million individuals worldwide, with women exhibiting a 50% higher likelihood of diagnosis than men. Despite significant advancements in treatment, MDD remains a chronic and relapsing disorder, necessitating the exploration of novel therapeutic interventions. This study focuses on the AKT1 gene, a key player in neuropsychiatric disorders, and investigates its interactions with natural phytochemicals as potential alternatives to conventional …
Published in Research and Reviews : Journal of Computational Biology · Vol. 14, Issue 2, 2025 Read article
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Next-Generation mRNA Vaccines: Applications Beyond COVID-19
Abstract: Messenger RNA (mRNA) vaccine technology has become a paradigm shift in contemporary medicine and, with remarkable success in the COVID-19 pandemic, has opened the door to a new wave of vaccines development. In contrast to the traditional vaccine methods, mRNA vaccines are based on the synthetic genetic code that allows host cells to express target antigens, thus eliciting strong humoral and cellular immunity. The speed of development, efficacy, scalability of …
Published in International Journal of Vaccines · Vol. 3, Issue 2, 2026 · pp. 15–26 Read article
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Risk & Opportunities in Development of new Drugs: A New Perspective
Abstract: The procedures of drug discovery and development are briefly described in this article. Our goal is to assist researchers whose work may be pertinent to the discovery and/or development of new drugs in framing their research reports in a way that appropriately situates their findings within the drug discovery and development process and supports the efficient translation of preclinical research to humans. One overarching theme of our article is the …
Published in Recent Trends in Infectious Diseases · Vol. 1, Issue 2, 2024 · pp. 19–28 Read article
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Review article on Quality Control in Clinical Trials
Abstract: Quality control (QC) is a critical component in the conduct of clinical trials, ensuring the accuracy, reliability, and credibility of data collected throughout the study. It encompasses a systematic set of procedures designed to monitor trial conduct and data integrity, thus safeguarding the rights, safety, and well-being of participants. This review explores the principles, implementation, and evolving practices of quality control in clinical trials, highlighting its importance across all phases …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 3, 2025 · pp. 01–07 Read article