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24 articles for “Plaque”
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Kisunla (Donanemab): A Novel Breakthrough Illuminating a Path to Better Alzheimer’s Outcomes
Abstract: Background: Alzheimer’s disease (AD) is a progressive neurodegenerative condition marked by cognitive decline, memory loss, and loss of independence. Despite decades of extensive research, disease-modifying treatments have been limited in success. Recent therapeutic advancements have led to the development of monoclonal antibodies targeting amyloid-beta (Aβ) plaques, particularly the pyroglutamate-modified variant, a key pathological hallmark of AD. Objectives: This review aims to explore the therapeutic potential of Donanemab (Kisunla), a novel …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 15, Issue 3, 2025 · pp. 37–45 Read article
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Seroprevalence and Immunity to Dengue Virus Among Women in Punjab: A Public Health Concern
Abstract: Dengue virus (DENV) infection continues to be a public health concern in Punjab, India, where women are at higher risk because of socioeconomic factors. This cross-sectional study sought to assess the DENV seroprevalence, their neutralizing antibody profiles, and the risk factors associated with DENV among a sample of 1,200 women (aged 18–50 years) in Punjab. Serum samples were processed by IgG/IgM ELISA, and plaque reduction neutralization tests (PRNT90) were done …
Published in Research and Reviews : A Journal of Immunology · Vol. 16, Issue 1, 2026 · pp. 6–10 Read article
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Photonic Diagnostics: Harnessing Optical Sensing for Non-Invasive Assessment of Coronary Obstruction
Abstract: Cardiovascular diseases (CVDs) remain the leading cause of mortality globally, with coronary artery blockages primarily atherosclerosis representing a critical challenge. The gold standard for diagnosing coronary artery disease remains invasive coronary angiography, a procedure that, while precise, carries inherent patient risks, high costs, and logistical burdens. Optical sensors, leveraging the principles of light-tissue interaction, offer real-time, high-resolution insights into vascular health, paving the way for early detection of arterial stenoses …
Published in International Journal of Optical Innovations & Research · Vol. 4, Issue 1, 2026 · pp. 25–30 Read article
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Formulation and Evaluation of Golden Heart’s Tooth paste of Piper Betel
Abstract: Toothpaste is a multifunctional oral care product composed of abrasives, surfactants, fluoride-based anticaries agents, and pH buffers. Herbal toothpaste formulations have gained significant attention for the treatment of gingivitis, an inflammatory disease of the gums. Generally, toothpaste formulations maintain a pH range of 5–6 to ensure stability and compatibility with the oral environment. Traditional medicinal plants have long been used by communities for oral healthcare due to their antimicrobial and …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 13, Issue 2, 2026 Read article