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25 articles for “Neurological Personalized”
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Graphene-Polymer Nanocomposites for Drug Delivery Applications
Abstract: Graphene-polymer nanocomposites (GPNCs) have gained significant attention in drug delivery due to their exceptional physicochemical properties, including high surface area, mechanical strength, tunable functionality, and biocompatibility. These nanocomposites integrate graphene derivatives, such as graphene oxide (GO) and reduced graphene oxide (rGO), with biocompatible polymers to enhance drug loading efficiency, stability, and controlled release. Various natural (chitosan, alginate) and synthetic (PLGA, PEG, PCL) polymers are used to functionalize graphene, enabling targeted …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 362–374 Read article
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RNA- Based Drug Delivery, Current Advances, Pharmaceutical Applications, and Future Perspectives
Abstract: RNA-based therapeutics have emerged as a transformative approach in modern medicine due to their ability to regulate gene expression with high specificity and precision. Advances in molecular biology, RNA chemistry, and nanotechnology have accelerated the development of diverse RNA modalities, including messenger RNA (mRNA), small interfering RNA (siRNA), microRNA (miRNA), antisense oligonucleotides (ASOs), and RNA aptamers. These therapeutics offer promising strategies for the treatment of cancer, genetic disorders, infectious diseases, …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 13, Issue 2, 2026 Read article
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Alzheimer’s Disease Detection Using ML Algorithm
Abstract: A degenerative neurological state of affairs, Alzheimer's disease (AD) gradually impairs cognitive and functional capacities, especially in people over 65. Early AD detection is crucial for efficient management and treatment prep. This study delves into novel approaches for the early detection of AD using non-invasive methods. We've implemented a blend of neuroimaging data analysis and machine learning algorithms to pinpoint markers indicative of the disease during its initial phases. Our …
Published in Journal of Experimental & Applied Mechanics · Vol. 15, Issue 3, 2024 · pp. 53–57 Read article
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Biodegradable and Natural Fiber-Reinforced Polymer Composites for Co-Delivery of Multiple Therapeutic Agents
Abstract: The co-delivery of multiple drugs using advanced nanocarriers has revolutionized targeted therapy in various diseases, particularly in cancer, infectious diseases, and neurological disorders. Multi-layered polymeric nanocarriers (MLPNs) offer a sophisticated platform to encapsulate multiple therapeutic agents with precise control over drug release, bioavailability, and synergistic effects. These nanocarriers are designed with distinct polymer layers that enable sequential or simultaneous drug release based on stimuli-responsive mechanisms such as pH, temperature, and …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 406–419 Read article
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Polymeric Materials in Assistive Devices for Cerebral Palsy: Advances and Applications
Abstract: The neurological condition known as cerebral palsy (CP) impairs muscle coordination and movement often necessitating assistive devices for mobility, support, and rehabilitation. These devices are crucial for enhancing CP patients' quality of life by boosting their independence, comfort, and overall functionality. Recent advancements in polymer chemistry have revolutionized the development of assistive devices, offering enhanced flexibility, durability, and biocompatibility. The integration of polymeric materials in orthotic supports, adaptive braces, and …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 316–322 Read article