Search
29 articles for “DNA interaction”
-
Molecular Docking-Based Analysis of Rauvolfia serpentina Alkaloids Targeting HPV E1 and L1 Proteins for Antiviral Therapeutic Potential
Abstract: Human papillomavirus (HPV) is a major cause of cervical cancer and other epithelial cancers. E1 and L1 proteins are crucial to the virus's lifespan. E1 is a viral helicase that is needed for HPV DNA replication, and L1 is the main structural capsid protein that builds the virion and infects target cells. Going after these proteins is a good way to stop viruses from spreading. In this case, Rauvolfia serpentina, …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 17, Issue 1, 2026 · pp. 100–113 Read article
-
A Review on Unmasking Merkel Cell Polyomavirus: From Discovery to Cancer Driver
Abstract: Merkel cell polyomavirus (MCPyV) is a small, non-enveloped, circular double-stranded DNA virus belonging to the Polyomaviridae family, first characterized in 2008. Epidemiological data suggest widespread exposure, with seroprevalence rates approaching 80% in adults. While primary infection is typically asymptomatic, rare integration events in Merkel cells can initiate oncogenesis, yielding Merkel cell carcinoma (MCC), a neuroendocrine skin cancer with a five-year survival rate under 60%. This review integrates findings from six …
Published in International Journal of Virus Studies · Vol. 2, Issue 2, 2025 · pp. 6–11 Read article
-
Review on Morinda citrifolia L.—Noni Juice
Abstract: Noni juice is a globally popular health beverage originating in the tropics and used since long in traditional medicines in certain areas around the globe. A review published that noni juice may provide protection against tobacco smoke-induced DNA damage, blood lipid and homocysteine elevation as well as systemic inflammation. Morinda citrifolia contains phytochemicals that own antibacterial, antiviral, antifungal, antitumor, anthelminthic, analgesic, hypotensive, anti-inflammatory, immune enhancing effects, improve joint health, increase …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 7, Issue 1, 2020 · pp. 55–60 Read article
-
Advancements in Molecular Engineering: Innovations at the Nexus of Chemistry and Technology
Abstract: Molecular engineering, a frontier of chemistry, merges precision and innovation to design and assemble molecular structures with unprecedented control. This abstract explores recent advances, highlighting key breakthroughs and their transformative impacts. Starting with its roots in chemical synthesis and materials science, it traces the evolution towards rational design driven by computational tools and advanced characterization techniques, enabling tailored molecular architectures. A focal point is programmable molecules, where DNA nanotechnology principles …
Published in International Journal of Advance in Molecular Engineering · Vol. 1, Issue 2, 2023 · pp. 37–43 Read article
-
Computational Analysis of Tinospora Cordifolia Phytochemicals as Potential Inhibitors of BRCA1-BRCT Domain Interaction in Breast Cancer
Abstract: Breast cancer is a leading cause of cancer-related deaths worldwide, accounting for a significant proportion of mortality rates among women. Despite current therapeutic approaches, the disease remains characterized by molecular heterogeneity, making it challenging to develop effective treatments. This study explores the potential of Tinospora cordifolia, a medicinal plant, in breast cancer therapy. Guduchi, scientifically known as Tinospora cordifolia, boasts a centuries-long history of use in traditional medicine, with a …
Published in International Journal of Molecular Biotechnological Research · Vol. 3, Issue 1, 2025 · pp. 27–37 Read article
-
Plant Evolutionary Biology: An Insight into Adaptations and Diversity
Abstract: The study of plant evolutionary biology provides crucial insights into the remarkable diversity and adaptation of plants. This review work aims to explore the fascinating world of plant evolution, discussing key concepts, patterns, and mechanisms that have shaped the plant kingdom over millions of years. The review begins by highlighting the immense diversity of plant species, categorizing them into major groups and elucidating their distinctive characteristics. It further examines the …
Published in Research & Reviews : Journal of Botany · Vol. 12, Issue 1, 2023 · pp. 18–23 Read article
-
The Essences of Nanotechnology and its Role in Molecular Nanoelectronics & Communication
Abstract: In this paper, the essence of nanotechnology is reviewed. Most of the properties of nanomaterials and structures arising from the synthesis and growth conditions and physical theory are reviewed. Hence, some of the techniques of synthesizing nanomaterials and theoretical methods used to describe the physical and bio – chemical properties are highlighted. The theoretical formalism is intended to describe the interactions of spins and electrons in atomic scale. The consensus …
Published in Nano Trends – A Journal of Nano Technology & Its Applications · Vol. 24, Issue 2, 2022 · pp. 1–16 Read article
-
Electromagnetic Field Effects on Biological Systems and Safety Evaluation of Microwave Exposure
Abstract: The increasing use of wireless communication systems, radar technologies, and microwave- based devices has raised growing concerns regarding the potential biological effects of electromagnetic fields (EMFs) on living systems. This review paper investigates the interaction between electromagnetic field exposure, particularly in the microwave frequency range, and biological tissues, with a focus on safety implications and risk assessment. Microwave radiation, commonly emitted from mobile phones, Wi-Fi routers, and industrial equipment, can …
Published in Journal of Microwave Engineering and Technologies · Vol. 13, Issue 1, 2026 · pp. 26–33 Read article
-
Genetic Variability and Statistical Methods: Key Insights for Computational Genetics Research
Abstract: Genetic variability, defined as the differences in DNA sequences among individuals, serves as the foundation of evolutionary biology and plays a pivotal role in species’ adaptability, resilience, and overall survival. Advances in genomic technologies, particularly high-throughput sequencing, have enabled unprecedented exploration of genetic diversity, fostering the growth of computational genetics. This interdisciplinary field combines statistical methods and computational tools to analyze genetic data, identify patterns, and link phenotypes to genotypes. …
Published in Research and Reviews : Journal of Computational Biology · Vol. 13, Issue 3, 2024 · pp. 19–23 Read article