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1982 articles for “potential” (ranking capped at the first 2,000 matches — narrow the search to see the rest)
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Network Pharmacology and Molecular Docking Approach to Reveal the Underlying Mechanisms of Isorhamnetin in the Treatment of Lymphangitis Carcinomatosis
Abstract: Objective: Lymphangitic carcinomatosis (LC) is a tumor that spreads through lung lymphatics and is most commonly seen secondary to adenocarcinoma. In the majority of cases, LC is a result of tumor cells spreading through the lymphatic system. However, approximately 20% of LC cases can be attributed to lymphangitis caused by tumors obstructing lymphatic drainage. This blockage commonly occurs near the lung hilum, where a centrally located mass can cause inflammation …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 1, Issue 1, 2023 · pp. 28–45 Read article
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A Study to Determine the Impact of a Structure Teaching Program on the Knowledge of Needle Stick Injury Among Hospital Staff Nurses
Abstract: Needle stick injuries occur when needles accidentally puncture the skin, posing a risk to individuals working with hypodermic syringes and other needle equipment, particularly in healthcare settings. These injuries are recognized as occupational hazards in the medical field and raise concerns about the potential transmission of blood-borne illnesses, including hepatitis B virus (HBV), hepatitis C virus (HCV), and human immunodeficiency virus (HIV). Although the immediate physical effects of needle stick …
Published in International Journal of Community Health Nursing And Practices · Vol. 1, Issue 2, 2023 Read article
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The Role of Cholesterol in Biological Membranes
Abstract: Cholesterol plays the role of a regulator that ensures the correct packaging of the lipid part of the membrane, which is necessary for its normal operation, by influencing on the mobility of the fatty acid tails of membrane lipids: if the membrane is too rigid and there is a danger of "freezing" of fatty acid chains, cholesterol causes it to liquefy, since the chains in its presence become more mobile; …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 1, Issue 1, 2023 Read article
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Molecular Docking of Cocculus hirsutus Phytocompounds with the Selective DENV Virus Stereotypes
Abstract: Dengue is a tropical disease with a high infection rate worldwide. Though treatments are available for the symptoms, anti-dengue drugs are unavailable. To tackle this issue, the study aims to shortlist the potential phytocompounds from Cocculus hirsutus medicinal plant, prevalent in South and South East Asia. Using molecular docking and ADME analysis, two potential compounds possessing high drug-likeness are identified namely, Sinococuline and Morphinan.
Published in International Journal of Genetic Modifications and Recombinations · Vol. 1, Issue 1, 2023 · pp. 17–29 Read article
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Knowledge and Perception of the Ill Effects of Cosmetics Among Late Adolescent Girls
Abstract: The current research focused on examining the knowledge and attitude towards the negative effects of cosmetics among late adolescent girls studying at DM WIMS Pharmacy College in Meppadi, Wayanad. The study aimed to evaluate the level of knowledge and attitude toward the harmful effects of cosmetics among these girls and explore any potential associations between their knowledge, attitude and selected socio-demographic variables. To conduct the study, a quantitative approach using …
Published in International Journal of Women's Health Nursing And Practices · Vol. 1, Issue 1, 2023 · pp. 15–20 Read article
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A Computational Study to Elucidate the Phytochemicals as An Antagonist Against Pruritis in Psoriasis
Abstract: Objective: Psoriasis is a chronic, non-contagious, auto-immune skin disorder that causes inflammation, pain, and itching in the affected areas. The etiology of this condition is not entirely understood, and while there are treatments available to manage the symptoms, there is currently no cure. The Transient receptor potential cation channel, subfamily Vanillin, member 3 (TRPV3), present in keratinocytes, allegedly had a part in the development of psoriasis-related pain and itching. Specifically, …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 1, Issue 2, 2023 · pp. 49–61 Read article
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Scope of Nurse Led Preventive Oncology Clinic in India
Abstract: India holds immense potential and a promising future for the extensive implementation of nurse-led preventive oncology clinics, considering its substantial burden of cancer-related morbidity and mortality. The healthcare system in India is not equipped enough to cater to the growing needs of the population, and there is a lack of preventive services, particularly for cancer. In this context, nurse-led preventive oncology clinics can play a pivotal role in addressing the …
Published in International Journal of Oncological Nursing and Practices · Vol. 1, Issue 1, 2023 · pp. 12–16 Read article
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Development and Evaluation of a Novel Polyaniline/Polyvinyl Alcohol/Silver Nanocomposite for Antibacterial Applications: Synthesis and Characterization
Abstract: A novel nanocomposite made up of polyaniline, polyvinyl alcohol, and silver (PAL/PVA/Ag) was synthesized using the reduction of chemical technique in this study. Aniline was polymerized in situ with ammonium persulfate to create polyaniline (PAL), while Ag+ ions were employed to make an nanoparticle of Ag colloidal solution. The combination of Ag nanoparticles with the PAL/PVA composite resulted in the development of a new nanocomposite. Scanning electron microscopy (SEM) and …
Published in Journal of Polymer & Composites · Vol. 11, Issue 3, 2023 · pp. 39–47 Read article
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In Silico Analysis and Docking Study of the Active Phyto Compounds of Ginkgo Biloba Against Alzheimer's Amyloid-Beta Protein
Abstract: Objective: Alzheimer's disease, an age-related progressive neurological condition, arises due to the accumulation of amyloid-beta protein within the brain. In this study, an attempt was made to explore the potential of natural compounds derived from Ginkgo, known for their diverse medicinal properties, in the prevention of the disorder by employing molecular docking techniques, conducting drug-likeness prediction assessments, and performing ADME analysis. Methods: Amyloid beta protein was retrieved from the PDB …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 1, Issue 2, 2023 Read article
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Brain Machine Interface: A Review of Current Technologies and Future Directions
Abstract: Brain Machine Interface (BMI) is a rapidly growing field that aims to establish direct communication between the brain and an external device. This technology has the potential to restore lost motor and sensory functions in people with neurological disorders or injuries. A brain-computer interface (BCI) is a technology that converts signals from the brain into instructions for computers or other gadgets. This innovation allows individuals to engage with their surroundings …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 1, Issue 1, 2023 · pp. 14–24 Read article
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Drugs for Alzheimer’s Disease from Salix Alba Discovered Computationally Utilizing Virtual Screening and Docking against 1b41 Protein
Abstract: Objective : The of this research is to evaluate the feasibility of using molecular docking techniques to identify novel acetylcholinesterase, a key enzyme implicated in the pathogenesis of Alzheimer’s disease, a neurodegenerative disorder with a gradual but steady progression to death, due to the gradual accumulation of beta-plaques and neurofibrillary tangles, as well as a decline in acetylcholine levels. Due to its function in converting acetylcholine into acyl and choline …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 1, Issue 2, 2023 · pp. 07–19 Read article
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A Molecular Docking Study: Targetting HIV-1 Integrase Protein Against Selected Phytocompounds from Calophyllum Lanigerum
Abstract: Objectives: The most common form of HIV that causes AIDS is HIV-1. The World Health Organization has estimated roughly 75 million plus HIV-1 infections till date and roughly 40 million deaths (as of 2021). Thus, this study was done to identify natural compounds from Calophyllum lanigerum, a medicinal plant largely endemic to South-East Asia, to inhibit the spread of this disease. It did so by using molecular docking methods, Lipinski …
Published in International Journal of Molecular Biotechnological Research · Vol. 1, Issue 2, 2023 · pp. 43–55 Read article
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Molecular Docking Study: Targeting mycobacterium leprae ML2640 Protein Using Active Compounds from Coscinium fenestratum
Abstract: Objectives: Leprosy is an infectious disease in skin, peripheral nerve and mucosa of upper airway. Around 70% of this infection is caused by Mycobacterium leprae, which was discovered during1873. Multi drug therapy is used for the treatment, still multiple drug resistance and reactions has been reported among patients. Hence, this work focused on identifying bioactive compounds from Coscinium fenestratum that can target mycobacterium leprae ML2640 protein by in-silico approach. Method: …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 1, Issue 2, 2023 · pp. 21–33 Read article
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Fabrication and Characterization of Zinc-based Alloy for Bio-implants
Abstract: Zinc-based alloys are potential biodegradable implants and can replace Magnesium and Titaniumbased materials via engineering their biomechanical properties with Zinc. Implants, due to their intricate geometries are difficult to fabricate by conventional manufacturing techniques. Therefore, they are usually fabricated by Additive manufacturing and Powder metallurgy techniques. In the present work, Zinc, Magnesium, manganese and titanium are alloyed using powder metallurgy technique. Vickers micro-hardness, UTM, Zeiss microscopy and Corrosion testing using …
Published in Journal of Polymer & Composites · Vol. 11, Issue 7, 2023 · pp. 1–13 Read article
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Machine Learning Based Early Cataract Detection: A Predictive Modeling Approach
Abstract: Cataracts, characterized by dense cloudy areas in the eye’s lens, afflict more than 50% of elderly individuals, leading to impaired vision and potential blindness. Detecting cataracts at an early stage is crucial to facilitate simpler treatments, as neglecting the condition may necessitate complex eye surgery. To address this issue, we are creating a predictive system that identifies cataract disease by analyzing user-provided eye features. To achieve this, we leverage OpenCV, …
Published in International Journal of Computer Science Languages · Vol. 1, Issue 2, 2023 · pp. 1–8 Read article
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Environmental Advantages of Renewable Energy: A Review
Abstract: There is a shortage of fuel in many emerging nations, including India, because of increased manufacturing for many different development initiatives. If the thermal energy sources used to meet this rise in demand are coal-based, environmental damage and high production costs ensue. So, the greatest alternative approach is for the nation to build renewable energy-based power facilities. Sustainable in light of current and future societal, economic, and social demands, renewable …
Published in International Journal of Environmental Noise and Pollution Control · Vol. 1, Issue 1, 2023 · pp. 31–39 Read article
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Extrapolations of Periwinkle Secondary Metabolites as Multitarget Inhibitor of Breast Cancer Proteins
Abstract: Objective: Breast cancer is considered one of the most common and dangerous forms of cancer. It is a significant public health issue on a global scale. The study estimates that 10.0 million people will die from cancer this year, and 19.3 million people will develop the disease overall (BC). In this computation approach, nowadays emphasizes new drug discovery, the target protein epidermal growth factor receptor (EGFR) (5UGB), estrogen receptor (ER) …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 1, Issue 1, 2023 · pp. 36–49 Read article
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Valeton Phytoconstituents from Curcuma Phaeocaulis as Prion Protein Mutant V210I Inhibitors: A Computational Docking and Virtual Screening Study
Abstract: Objective: Creutzfeldt-Jakob disease (CJD), a neurological disorder that is sporadic, fatal, communicable, and worsens rapidly, is caused by abnormal folding of prion proteins. Identifying and assessing the potential of phytocompounds from the Curcuma phaeocaulis Valeton plant as a new therapeutic candidate aimed at the treatment of CJD is the objective of this research article. Methods: In this experiment, we assessed outcomes following an in-silico assessment to design a new oral …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 1, Issue 2, 2023 · pp. 1–16 Read article
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Benefaction of Nutraceuticals for Human Health: Review
Abstract: Nutraceuticals are a broad category of palatable natural chemicals that are thought to offer benefits beyond their nutritional content. These can include foods high in nutrients, foods with therapeutic properties, or certain ingredients found in some foods, like dietary fiber, hydrolyzed protein, garlic, ginger, omega-3, soybean, minerals, vitamins, fortified foods, enriched foods, and even recombinant goods. People are becoming more concerned about their health due to the long work hours …
Published in Recent Trends in Infectious Diseases · Vol. 1, Issue 1, 2024 · pp. 1–12 Read article
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Bioethanol and Beyond: A Comprehensive Review on Sustainable Biofuels for Global Energy Demands and Environmental Conservation
Abstract: This comprehensive review explores the concept of "biofuels," specifically focusing on energy-enriched chemicals generated through biological processes or derived from the biomass of living organisms, including microalgae, plants, and bacteria. As the global population continues to increase, there is a growing demand for more energy supplies to enhance the quality of life. Biofuels, harnessed from various sources such as sugar, starch, and organic waste, have emerged as potential solutions to …
Published in Recent Trends in Infectious Diseases · Vol. 1, Issue 2, 2024 · pp. 1–9 Read article