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341 articles for “genetic study”
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Character Association and Path Analysis for Yield Contributing Traits in Wheat (Triticum aestivum L.)
Abstract: A field experiment was laid to study correlation and path co-efficient analysis for 14 traits. The genotypic correlation co-efficient were found to be of higher magnitude than the corresponding phenotypic correlation co-efficient in most of the cases. Grain yield was highly significant and positively correlated with number of tiller per plant whereas strong positive and highly significant correlation also exhibited by plant height at genotypic level however highly significant and …
Published in Research and Reviews : Journal of Crop science and Technology · Vol. 8, Issue 1, 2019 · pp. 1–5 Read article
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Drug Repurposing of Anticancer Agents JP-8g and REDX05358 Against the Target Protein Plectin 1a in Epidemolysis Bullosa Simplex with Muscular Dystrophy (EBS-MD)
Abstract: Epidermolysis Bullosa Simplex with Muscle Dystrophy is a genetic disease affecting the skin and muscles which can be seen at birth or start at adulthood due to the mutation in the protein Plectin 1a (PLEC gene) causing skin blisters and muscle weakness. This protein is seen in sarcolemma, Z disks in skeletal muscles, hemidesmosomes in skin and cardiac muscles giving stability to cytoskeleton, playing a crucial role in neuromuscular transmission …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 3, Issue 2, 2025 · pp. 22–34 Read article
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Chronic Obstructive Pulmonary Disease (COPD) in Younger Adults: Challenges and Considerations – A Review
Abstract: Chronic Obstructive Pulmonary Disease (COPD) phenomenon rapidly converting into chronic significant health issues for many young adults. A disease calculated for older age gives way to early-onset COPD, which creates new issues for diagnosing and treating the illness and even interacts with the quality of life. The article reviews the epidemiology, risk factors, pathophysiology, clinical presentation, and treatment considerations related to this set of conditions. From those risk factors, early-onset …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 3, 2025 · pp. 08–19 Read article
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Development of Fast and Power Efficient Elevator
Abstract: The rapid urbanization and vertical expansion of cities have led to a surge in the construction of high-rise buildings, creating a growing demand for elevator systems that are not only fast but also energy efficient. As population density in metropolitan areas increases, the pressure on vertical transportation systems intensifies, highlighting the need for solutions that can handle high passenger traffic without compromising performance or sustainability. This study presents the development …
Published in International Journal of Advanced Robotics and Automation Technology · Vol. 3, Issue 2, 2025 · pp. 32–41 Read article
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Host Interface of Cystic Fibrosis and P. aeruginosa
Abstract: A clash between microbial infection and host immunity can contribute to multiple diseases. Cystic fibrosis is one of those diseases. It’s an autoimmune disorder and hyperinflammatory disease, caused by pseudomonas aeruginosa, it’s the most predominant pathogen causing this disease. The progression of the lung infection cystic fibrosis is driven by host pathogen interface that focuses on the host and the bacterial factors. The disease has an interplay between the host, …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 14, Issue 3, 2024 · pp. 9–31 Read article
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Comparative Evaluation of Pedigree-Based and Genomic BLUP Models for Wheat Grain Yield Prediction
Abstract: Before genome-wide molecular markers became affordable, plant and animal breeding relied on pedigree-based prediction (P-BLUP), using the expected additive relationship matrix (A) derived from recorded ancestry. Genomic selection replaced or augmented this with a marker-derived genomic relationship matrix (G; GBLUP), and single-step methods combining A and G are now standard when only a subset of a breeding population is genotyped. It is less clear whether pedigree information retains any predictive …
Published in Research and Reviews : Journal of Computational Biology · Vol. 15, Issue 2, 2026 · pp. 1–9 Read article
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Gene prioritization of colorectal cancer using computational approach
Abstract: Colorectal cancer (CRC) continues to be a major worldwide health issue, underscoring the need to pinpoint crucial genetic elements influencing its initiation and advancement. In this investigation, we utilize sophisticated computational methods to prioritize potential genes linked to CRC development. Through the utilization of various bioinformatics tools and comprehensive methodologies, we systematically examine extensive microarray datasets to identify potential genetic contributors. Initially, a vast amount of CRC microarray data (approximately …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 2, Issue 1, 2024 · pp. 39–52 Read article
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Artificial Intelligence in Image Recognition: Context of Machine Vision
Abstract: The machine learning discipline is as old as decades, but some problems such as image recognition, location detection, image classification, image generation, speech recognition, and natural language processing cannot be solved. Image classification studies are another basic, most classic and essential line of research in deep learning. Computer intelligent recognition of the images technology has enabled a gradual reaction (updating) to foreign measurement trends, which promotes advancement of different areas …
Published in Journal of Image Processing & Pattern Recognition Progress · Vol. 12, Issue 3, 2025 · pp. 01–06 Read article
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Prevalence of Perceived Stigma and Associated Factors among People with Epilepsy in Mekelle, Tigray, Ethiopia, 2019
Abstract: AbstractBackground: Epilepsy is defined as the most common, chronic, noninfectious neurologic disease that attacks around fifty up to sixty-nine million peoples without any age, sex, religion, ethnicity boundaries. Stigma is typically a practiced or predicted social system, characterized by exclusion or rejection of a person or group. Now a day perceived stigma among people with epilepsy become public health problems in the world. Perceived stigma in epileptic patients affects many …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 10, Issue 2, 2020 · pp. 24–35 Read article
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Progeria Syndrome Unveiled: A Scientific Odyssey into Premature Aging Mechanisms and Therapeutic Frontiers
Abstract: Progeria, or Hutchinson-Gilford Progeria Syndrome (HGPS), is a rare and fatal genetic disorder in childhood, exhibiting features akin to premature aging. Despite normal appearances in infancy, affected children face accelerated aging with distinct facial characteristics, including micrognathia, dental malformations, lower body weight, early hair loss, decreased joint mobility, lipodystrophy, etc. The cause of HGPS is a point mutation that occurs at the exon 11 of the LMNA gene which normally …
Published in Research and Reviews: A Journal of Health Professions · Vol. 14, Issue 2, 2024 · pp. 52–68 Read article
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Numerical Simulation of Hybrid GSA Based Optimal Power Flow for Multi Objective Optimization Strategy
Abstract: Restricted nonlinear optimization in electric power systems engineering is a topic of Optimal Power Flow (OPF) that has been extensively investigated. It has been a long and remarkable history for the OPF, which was founded in the 1960s, of research and publication. Newcomers to OPF research face a challenging undertaking since there is so much information available and because OPF's popularity within the electric power systems community has prompted authors …
Published in Journal of Instrumentation Technology & Innovations · Vol. 11, Issue 3, 2021 · pp. 24–32 Read article
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Cadmium Accumulation in Different Tissues and DNA Content Alteration in Cat Fish (Clarias batrachus) Exposed to Lethal Concentration of Cadmium
Abstract: In the present study, the acute toxicity experiment was conducted to evaluate LC50 of Cadmium chloride (CdCl2) on Clarias batrachus which was found to be 450 ppm for 96 h. Clarias batrachus (average length of 8.5 ± 0.4 cm and the average weight of 13.5 ± 0.393 g) was exposed to sub-lethal concentration (140 ppm) and lethal (450 ppm) concentrations of Cd for 14 days. The Cd accumulation in tissues …
Published in Research and Reviews: A Journal of Toxicology · Vol. 10, Issue 3, 2020 · pp. 1–8 Read article
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A Novel WPFM-Transformer Framework for DNA Sequence Classification using FASTA Data
Abstract: The identification of genetic variants, tracing of disease-associated mutations, and the reconstruction of evolutionary relationships from raw sequence data are all achieved by the analysis of DNA sequence. The FASTA format is plain text and is an easy-to-read format, which is why it has endured four decades of the field's growth into bioinformatics. Classical alignment programs like BLAST and Smith-Waterman work well with small data sets, but are limited by …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 4, Issue 2, 2026 Read article
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Artificial Intelligence in Diagnostics: Advancements, Challenges, and Future Prospects
Abstract: AI is changing (and will change) healthcare as we know it, and diagnostics might be the specialty that feels the most discomfort. Artificial intelligence-based analytical systems are facilitating the detection, diagnosis, and treatment of a variety of diseases, with better accuracy, speed, and results. Now, this abstract investigates the role of AI in diagnostics, scouring its elements, landmark techniques, transformative impact and future overview. This article explains AI and discusses …
Published in Research and Reviews: A Journal of Health Professions · Vol. 15, Issue 3, 2025 · pp. 8–17 Read article
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Molecular Docking of Arjuna Tree Phytocompounds for Ischemic Heart Disease
Abstract: Heart disease is a serious condition that can be caused by several lifestyle changes and sometimes genetic problems. The primary protein component of apolipoprotein is the LDL receptor, which indicates that a reduction in LDL levels can reduce the risk of ischemic heart disease. Apolipoprotein levels are associated with increased levels of ischemic heart disease. Using ADMET analysis, drug likelihood prediction, and molecular docking, this work attempted to find natural …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 1, 2025 · pp. 42–52 Read article
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Evaluation Of Anti Obesity Activity Of Citrus Sinensis & Citrus Limon By High Fat Diet Induced Model Using Danio Rerio
Abstract: Obesity, defined by the World Health Organization (WHO) as an abnormal or excessive fat accumulation that may impair health, is becoming one of the greatest challenges to global health in this millennium, with more than 300 million men and nearly 450 million women obese globally in 2018. Obesity turns into serious problem globally. Zebrafish model can be used extensively for drug screening due to its low maintenance cost, comparatively short …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 1, 2024 · pp. 24–31 Read article
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Skin Cancer Detection System Based on Machine Learning for Recognition of Cancerous Images
Abstract: Skin cancer ranks among the most prevalent types of cancer globally and poses significant risks when left untreated. Skin cancer arises when abnormal cells proliferate uncontrollably in the skin. This uncontrolled growth can be triggered by genetic mutations, exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds, or various other factors. In this, the early detection of cancer plays a crucial role in treatment and …
Published in Research and Reviews: A Journal of Medicine · Vol. 14, Issue 2, 2024 · pp. 1–8 Read article
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Regional Variation in Amino Acid Composition, Antioxidant and Antimicrobial Activity of Tasar Sericin from North and South Bihar
Abstract: This study investigates geographical differences in biochemical and functional characteristics of sericin obtained from Antheraea mylitta cocoons sourced from two regions of Bihar, India: Bhagalpur (North) and Banka (South). Sericin was isolated via an alkali-assisted autoclaving process. Amino acid profiles were determined using HPLC. Free radical scavenging capacity was measured through DPPH, ABTS, and hydrogen peroxide assays. Antibacterial and antifungal effects were tested against Staphylococcus aureus, Escherichia coli, and Candida …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 16, Issue 2, 2026 · pp. 1–10 Read article
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Integrative Perspectives on Lipoma: Traditional Therapeutics from Siddha, Ayurveda, and Unani with Biomedical Correlates
Abstract: Background: Lipoma is the most common benign soft tissue tumor, with an incidence of approximately 2 per 1,000 individuals annually. Modern biomedicine attributes its pathogenesis to genetic abnormalities like HMGA2 rearrangements and dysregulated adipogenesis via PPARγ pathways. Effective pharmacological therapies are lacking. Traditional Indian systems – Siddha, Ayurveda, and Unani – offer unique perspectives and non‑surgical approaches yet remain underexplored in integrative research. Objective: To critically evaluate the descriptions, pathophysiological …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 13, Issue 1, 2026 · pp. 19–33 Read article
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A Systematic Review of the Herbal Medicinal Plants With Anti-Obesity Potential
Abstract: Obesity is a chronic, multifactorial metabolic condition characterized by abnormal fat accumulation. It is mainly driven by the intricate influence of genetic, environmental, hormonal, metabolic and lifestyle determinants. The burden of obesity has risen considerably over the past few years, making it one of the major health concerns in both developed and developing countries alike. The rapid increase globally in obesity prevalence is linked with numerous health complications such as …
Published in Research & Reviews : Journal of Herbal Science · Vol. 15, Issue 2, 2026 · pp. 31–38 Read article