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532 articles for “quantum mechanics/molecular mechanics (QM/MM)” (ranking capped at the first 2,000 matches — narrow the search to see the rest)
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FMR1 Key Biomarker in Fragile X Syndrome- A Comprehensive Review
Abstract: Fragile X Syndrome (FXS) is a complicated neurodevelopmental condition that causes intellectual disabilities, behavioural issues, and a variety of physical symptoms. Central to understanding FXS is the Fragile X Mental Retardation 1 (FMR1) gene, pivotal in the disorder's pathogenesis. This review examines FMR1 as a key biomarker in FXS, drawing on recent research insights. The FMR1 gene, situated on the X chromosome, encodes the fragile X mental retardation protein (FMRP), …
Published in International Journal of Brain Sciences · Vol. 1, Issue 2, 2024 · pp. 8–18 Read article
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Role of Centella asiatica in Alzheimer’s Disease: A Comprehensive Review
Abstract: Alzheimer's disease (AD) is a progressive neurological illness that causes cognitive decline and memory loss and affects millions of people worldwide. As synthetic medications often prove ineffective or cause severe side effects, natural remedies are gaining attention. This review explores the potential of Centella asiatica, a herb traditionally used in oriental medicine, in the treatment of Alzheimer's disease. Triterpenoids, asiaticoside, and madecassoside are among the bioactive substances found in Centella …
Published in International Journal of Brain Sciences · Vol. 1, Issue 2, 2024 · pp. 1–7 Read article
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Charging System for Electric Vehicle and Hybrid Electric Vehicle in Running Condition: A Review
Abstract: This study examines comparative studies of three different charging systems used in electric vehicles while they are moving or operating. It also deals with the idea of using an alternator at each wheel of the vehicle to charge the non-connected set of batteries, as well as a brief explanation of the principles, mechanisms, design, and constraints of fuel cells, solar panels, and regenerative brakes. These are some of the most …
Published in International Journal of Electrical Machine Analysis and Design · Vol. 2, Issue 2, 2024 · pp. 10–18 Read article
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Physiotherapeutic Strategies to Enhance Throwing Accuracy in Cricket Players
Abstract: Background: Throwing accuracy is a crucial skill for cricket players, impacting both individual performance and team success. Physiotherapeutic strategies can enhance throwing mechanics, strength, and flexibility, leading to improved accuracy. Objectives: This study aims to outline effective physiotherapeutic interventions that optimize throwing accuracy in cricket players. Methods: A comprehensive review of current literature and practices was conducted with 3 articles found through PubMed, Google Scholar & Research Gate year range …
Published in International Journal of Orthopedic Nursing and Practices · Vol. 2, Issue 2, 2024 · pp. 30–34 Read article
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Antimicrobial Peptides and Bacteriophages as Next-Generation Alternatives to Conventional Antibiotics
Abstract: The growing threat of antibiotic-resistant bacteria has underscored the urgent need for innovative alternatives to conventional antibiotics. Antimicrobial peptides (AMPs) and bacteriophages are gaining recognition as next-generation therapeutics due to their distinct mechanisms of action and ability to target resistant pathogens effectively. AMPs, which can be natural or synthetic, disrupt microbial membranes and offer broad-spectrum antimicrobial activity with a reduced likelihood of resistance development. Bacteriophages, as bacteria-specific viruses, provide precise …
Published in International Journal of Antibiotics · Vol. 2, Issue 1, 2025 · pp. 9–27 Read article
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Exploring the Therapeutic Potential of Phytohormones: Bridging Plant Immunity and Human Health
Abstract: This review highlights the multifaceted roles of phytohormones, including salicylic acid, abscisic acid, cytokinins, and brassinosteroids, emphasizing their contributions to plant immunity and potential therapeutic applications in human health. Phytohormones are critical regulators of plant growth, development, and defense, functioning as signaling molecules that activate and coordinate plant responses to biotic and abiotic stresses. Salicylic acid, in particular, is instrumental in systemic acquired resistance (SAR), a defense mechanism that strengthens …
Published in International Journal of Trends in Horticulture · Vol. 1, Issue 2, 2024 · pp. 20–23 Read article
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Evaluation of AGO Adsorption Rate Isotherms Using Adsorbent Formulation of Plantain Agbagba1 and Clay of Different Mix Ratio in Pollutant Remediation in Salt Water
Abstract: The application of some agro-based materials in combination with day soil, for the production of adsorbents were investigated in relationship to their performance in AGO (Diesel) treatment in a batch process unit. The research allows the model concept of Langmuir isotherm, Frundlich isotherm and Temkin Isotherm for the determination of the adsorption rate of the various isotherms with respect to the effect of the particle size and the mixed ratios …
Published in International Journal of Pollution: Prevention & Control · Vol. 2, Issue 2, 2024 · pp. 31–42 Read article
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Epidermolysis Bullosa and Its Role in Cervical Cancer: An Overview
Abstract: Epidermolysis Bullosa is a group of uncommon genetic disorders that primarily affect the skin and mucous membranes. It is marked by severe skin fragility and the formation of blisters even after minor trauma. Traditionally, the focus of Epidermolysis Bullosa research has been on its dermatological manifestations, which include recurrent blistering, scarring, and the potential for infections due to the compromised skin barrier. However, recent advancements in Epidermolysis Bullosa research have …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 2, Issue 2, 2024 · pp. 14–18 Read article
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Smart Air Filtration Systems for Cities: A Technological Approach to Reducing Urban Pollution
Abstract: Urban air pollution is considered one of the main ecologically critical issues of the 21st century since it threatens citizens' health through respiratory diseases, pathologies of the cardiovascular system, and even premature death. Regarding an extremely high level of pollution in large cities, it becomes necessary to realize technological solutions which could avoid the negative impact of this phenomenon. Smart air filtration systems have emerged as promising solutions for urban …
Published in International Journal of Environmental Noise and Pollution Control · Vol. 2, Issue 2, 2024 · pp. 27–42 Read article
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Frequency of Failed Spinal Anesthesia and Associated Factors in Cesarean Section at Mardan Medical Complex, Mardan, KP, Pakistan
Abstract: Objective: Spinal anesthesia is the preferred choice of anesthesia for parturients having cesarean sections. Despite the high percentage of success in providing acceptable surgical anesthesia, failure of spinal anesthesia has been reported. This study aims to determine the frequency and associated factors related to failed spinal anesthesia during cesarean sections in pregnant women. Methodology: This descriptive cross-sectional study included 149 pregnant women and was conducted at Mardan Medical Complex (MMC) …
Published in International Journal of Women's Health Nursing And Practices · Vol. 2, Issue 2, 2024 · pp. 1–9 Read article
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Assembly Process and Performance of A Micro Steam Power Plant
Abstract: Energy is an indispensable component of modern society, driving everything from industrial processes to household appliances, among the various sources of energy, steam power, a form of heat energy has played a pivotal role in the development of human civilization, paving the way for the Industrial Revolution and subsequent technological advancements. This study focused on the assembly and performance evaluation of a 5 kW steam power plant. The components of …
Published in International Journal of Industrial and Product Design Engineering · Vol. 2, Issue 2, 2024 · pp. 38–48 Read article
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Modeling and Analysis of a Diaphragm Micropump with Annular Actuation Using Bond Graphs
Abstract: Micropumps have been around for a while and are utilized for many things, including electrical cooling and biomedical applications. Numerous researchers have experimented with varying the chamber, diaphragm, pumping mechanism, or actuation mechanism materials to improve the device's performance. Despite this, the micropumps employed in the practical applications mentioned above fall short of meeting the necessary flow rates and pressure. In this study, annular actuation is proposed to enhance performance. …
Published in International Journal of Machine Systems and Manufacturing Technology · Vol. 2, Issue 2, 2024 · pp. 34–48 Read article
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QSAR Modeling of a Novel Series of Methoxylated Chalcones as Antioxidant Agents Against Gram-Positive Bacteria Staphylococcus aureus
Abstract: Background: Chalcones are aromatic ketones belonging to the flavonoid family. They are plant-based compounds and are widely found in nature. For centuries, these bioactive molecules have been utilized in various traditional medicines for the treatment of several ailments. Chalcones have antibacterial, antiviral, antimalarial, antifungal, antioxidant, and antileishmanial properties. They are also used to treat inflammation and cancer. Chalcones act as angiogenesis inhibitors, an important factor in cancer progression and metastasis. …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 3, Issue 1, 2025 · pp. 28–34 Read article
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Self-Healing Thin Films: Paving the Way for Smart, and Sustainable Corrosion Protection
Abstract: Corrosion is one of the serious problems that industries and infrastructures of every type face, ranked among such threats as huge economic losses and concerns to global safety. Recent developments in the area of self-healing thin films make them a really promising innovation for enhancing corrosion protection. This review considers the development, mechanisms, and applications of self-healing thin films. Detailed here are intrinsic and extrinsic self-healing strategies oriented toward chemical …
Published in International Journal of Crystalline Materials · Vol. 2, Issue 1, 2025 · pp. 22–45 Read article
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The Art of Drug Design and Process Chemistry
Abstract: The creation of safe and efficient medications depends heavily on the art of drug design and process chemistry. This multidisciplinary discipline designs and optimizes drug candidates for therapeutic uses by fusing the concepts of biology, chemistry, and engineering. Researchers can develop compounds with pharmacological activity by using logical drug design techniques if they have a thorough understanding of the molecular targets implicated in disease pathways. By making it easier to …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 1, 2025 · pp. 1–10 Read article
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The State of Air Quality: Pollution Sources, Health Implications, and Future
Abstract: Air quality is a critical component of environmental health, significantly affecting human well-being and ecological balance. Poor air quality has been related to a variety of health issues, including respiratory and cardiovascular disorders, and it is a major cause of early death worldwide. Understanding the origins, kinds, and impacts of air pollutants is critical for establishing effective pollution-reduction initiatives. This review focuses on the principal pollutants that affect air quality, …
Published in International Journal of Atmosphere · Vol. 1, Issue 2, 2024 · pp. 1–4 Read article
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Resource Reservation Approach: Application in Wireless Network
Abstract: This paper presents an enhanced resource reservation and call admission control strategy tailored for cellular networks. The proposed method uses user mobility trends to improve the efficiency of resource usage while avoiding significant network congestion. The call admission control mechanism is activated each time a new or handoff service request occurs, ensuring that resources are allocated efficiently to uphold a steady quality of service (QoS) for multimedia traffic. This mechanism …
Published in International Journal of Wireless Security and Networks · Vol. 3, Issue 1, 2025 · pp. 9–12 Read article
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Advancements in Electromechanical Modeling for Energy Harvesting and Actuators in Robotics and Design Engineering
Abstract: This article examines the expanding field of electromechanical modeling, highlighting the integration of energy harvesting, actuator behavior, and magnetic/electromagnetic analyses in the design and production of electromechanical systems. It discusses the application of the Galerkin method for modeling intricate vibrations and torque generation, with a particular focus on its use in actuators for robotics and induction motors. Significant advancements in energy harvesting methods, especially those utilizing mechanical vibrations, have led …
Published in International Journal of Electro-Mechanics and Material Behaviour · Vol. 2, Issue 2, 2024 · pp. 21–25 Read article
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Length–Weight and Girth Relationship, Condition Factor, and Stomach Contents of Pila Ovata from Otuoke/Otuaba River, Bayelsa State, Nigeria
Abstract: Otuoke/Otuaba River situated in Otuoke, Bayelsa State, Nigeria serves numerous purposes, such as fishing, laundry, human feacal disposal, amongst others. The river is home to Pila ovata, a mollusc which serves as a special delicacy in the meals of most Bayelsan due to its high protein content. The length-weight and girth relationship, condition factor and stomach contents of P. Ovata (Apple snail) from Otuoke/Otuaba River was studied. Snail samples were …
Published in International Journal of Marine Life · Vol. 2, Issue 1, 2025 · pp. 10–17 Read article
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Differential Privacy-Aware Data Sanitization for Multi-Level Security
Abstract: Multi-level security (MLS) models are fundamental for enforcing mandatory access control in high-security environments such as government, military, healthcare, and finance. However, traditional MLS frameworks, including the Bell-LaPadula and Biba models, often create rigid data silos, preventing efficient data utilization. Differential privacy (DP) presents a novel solution by enabling controlled information leakage while preserving confidentiality. By injecting statistical noise into query results, DP allows lower-clearance users to access sanitized versions …
Published in International Journal of Computer Science Languages · Vol. 3, Issue 1, 2025 · pp. 42–52 Read article