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412 articles for “PKA/CREB pathway”
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Nanostructured Catalysts for Sustainable CO2 Reduction: Advancing Green Chemistry and Polymer Composites
Abstract: This study provides a comprehensive analysis of advanced nanostructured catalysts designed to enhance the efficiency of artificial photosynthesis for sustainable fuel production. We systematically evaluated a range of nanomaterials—including metal oxides, plasmonic nanoparticles, and carbon-based composites—to determine their effectiveness in converting solar energy into storable chemical fuels. The catalysts were synthesized via sol-gel, hydrothermal, and green methods, and their properties were thoroughly characterized using XRD, SEM, TEM, UV-Vis spectroscopy, and …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 175–181 Read article
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Sustainable Innovations in Vapor Compression Systems: A Review of Heat Recovery and Environmental Performance
Abstract: Vapor compression refrigeration systems are widely used in residential, commercial, and industrial sectors, contributing significantly to global energy consumption and greenhouse gas emissions. This review explores sustainable innovations in vapor compression systems, focusing on waste heat recovery techniques and their impact on environmental performance. Key advancements include the integration of heat exchangers, ejector systems, and hybrid configurations that enhance energy efficiency while reducing refrigerant load and emissions. With a focus …
Published in Journal of Thermal Engineering and Applications · Vol. 13, Issue 1, 2026 · pp. 16–21 Read article
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Integrative Perspectives on Lipoma: Traditional Therapeutics from Siddha, Ayurveda, and Unani with Biomedical Correlates
Abstract: Background: Lipoma is the most common benign soft tissue tumor, with an incidence of approximately 2 per 1,000 individuals annually. Modern biomedicine attributes its pathogenesis to genetic abnormalities like HMGA2 rearrangements and dysregulated adipogenesis via PPARγ pathways. Effective pharmacological therapies are lacking. Traditional Indian systems – Siddha, Ayurveda, and Unani – offer unique perspectives and non‑surgical approaches yet remain underexplored in integrative research. Objective: To critically evaluate the descriptions, pathophysiological …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 13, Issue 1, 2026 · pp. 19–33 Read article
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Impact of Groundwater Pollution on Carcinogenic and Non-Carcinogenic Health Effects: A Review
Abstract: Groundwater is a critical source of drinking water in many regions worldwide, particularly in South and Southeast Asia, where dependence on untreated groundwater remains high. However, increasing groundwater contamination poses serious risks to human health. This review synthesizes recent peer-reviewed studies to examine the sources, distribution, and health impacts of major groundwater contaminants, with a focus on both carcinogenic and non-carcinogenic risks. Emphasis is placed on fluoride, nitrate, chromium, and …
Published in Research & Reviews : Journal of Ecology · Vol. 15, Issue 1, 2026 · pp. 40–46 Read article
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A study on Controlling Artificial Heart
Abstract: The artificial heart has moved from a visionary concept to a clinically viable organreplacement technology, yet its longterm success hinges on the sophistication of its control architecture. This paper presents a comprehensive investigation of closedloop control strategies that enable an artificial heart to mimic the dynamic, beattobeat adaptability of its biological counterpart. We first construct a highfidelity cardiovascular model that integrates ventricular elastance, systemic and pulmonary vascular compliance, and realtime …
Published in Journal of Control & Instrumentation · Vol. 17, Issue 1, 2026 · pp. 14–23 Read article
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Bridging Brain-Inspired Learning and Quantum Reasoning for Future AGI Systems
Abstract: This research paper presents a novel neuromorphic–quantum hybrid computing framework envisioned to advance intelligent systems toward artificial general intelligence. The architecture integrates brain-inspired spiking networks for adaptive, energy-efficient learning with quantum processors for non-classical optimization and reasoning. A shared synaptic–quantum memory layer enables dual information representation, while neuromorphic adaptive controllers provide real-time stabilization of noisy quantum circuits. While quantum processors offer features like superposition- enabled exploration and entanglement-based correlations that …
Published in Current Trends in Signal Processing · Vol. 16, Issue 1, 2026 Read article
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Ferroelectric Materials for Next-Generation Non-Volatile Memory Applications
Abstract: The continuous scaling of conventional memory technologies is increasingly constrained by limitations in power consumption, speed, endurance, and integration density. As data-intensive applications such as artificial intelligence, Internet of Things, and edge computing demand fast and energy-efficient memory solutions, alternative non-volatile memory technologies have gained significant attention. Ferroelectric materials, characterized by their reversible spontaneous polarization, offer a promising pathway toward next-generation non-volatile memory due to their intrinsic non-volatility, low operating …
Published in Journal of Microelectronics and Solid State Devices · Vol. 13, Issue 1, 2026 · pp. 1–9 Read article
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Machine Learning Assisted Optimization of Nanoscale MOSFET Parameters Using TCAD Simulation
Abstract: This paper presents a machine learning (ML) assisted framework for the multi-objective optimization of nanoscale bulk n-channel metal-oxide-semiconductor field-effect transistors (nMOSFETs) with a 10 nm physical gate length, high-k HfO₂ gate dielectric, and TiN metal gate. Technology computer-aided design (TCAD) simulations employing drift-diffusion transport, Shockley-Read-Hall recombination, Lombardi mobility degradation, and density- gradient quantum correction models are used to generate a parametric dataset of 2,400 device configurations spanning gate length (L), …
Published in Journal of Microelectronics and Solid State Devices · Vol. 13, Issue 1, 2026 · pp. 10–19 Read article
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Next-Generation Biodegradable Polymer Composites: Enhancing Mechanical and Thermal Performance through Green Reinforcements
Abstract: Next-generation biodegradable polymer composites, combining compostable matrices such as polylactic acid (PLA), polyhydroxyalkanoates (PHAs) and starch-based polymers with green reinforcements (e.g., nanocellulose, lignin, agricultural residues and other bio-fillers), offer a pragmatic route to reconcile high performance with end-of-life sustainability. This paper examines recent advances in the design, processing and interfacial engineering of such composites to enhance mechanical stiffness, strength, toughness and thermal stability while preserving—or intentionally controlling—biodegradation pathways. Emphasis is …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 1780–1794 Read article
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Experimental Analysis and Predictive Modeling of Mechanical Behavior in Epoxy Composites Reinforced with Waste Tyre Rubber Particles
Abstract: The disposal of end-of-life tyres poses a significant environmental and resource challenge owing to their large volumes and non-biodegradable nature. In this work, we explore the incorporation of waste tyre rubber particles (WTRP) into an epoxy resin matrix to develop sustainable polymer composites and examine their mechanical behavior both experimentally and through predictive modelling. Composites with differing epoxy: WTRP ratios (80:20, 75:25, 70:30 wt.%) and varying rubber particle mesh sizes …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 1754–1765 Read article
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Cellular Mechanisms of Autophagy in Carcinogenesis: A Narrative Review
Abstract: Autophagy is a highly conserved lysosomal degradation pathway essential for cellular homeostasis, metabolic adaptation, and survival under stress. In the context of carcinogenesis, autophagy exhibits a paradoxical and stage-dependent role. During early tumor development, autophagy acts as a tumor-suppressive mechanism by limiting genomic instability, oxidative stress, and chronic inflammation. Conversely, in established malignancies, cancer cells exploit autophagy to sustain growth, survive hostile tumor microenvironments, and resist anticancer therapies. Increasing evidence …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 15, Issue 1, 2026 · pp. 23–28 Read article
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Fabrication of Polydimethylsiloxane Composites with Nickel Nanoparticles: Unification and Current–Voltage Relationship
Abstract: Polydimethylsiloxane (PDMS)–nickel nanoparticle (NiNPs) nanocomposite films were fabricated and systematically investigated to understand their electrical transport behavior through current–voltage (I–V) characterization. Nanocomposite films with varying Ni nanoparticle filler concentrations (14.88 wt%, 15.77 wt%, and 16.65 wt%) were prepared using a solution-mixing and spin-coating technique, followed by controlled thermal curing. The electrical properties of both pristine PDMS and PDMS– NiNPs nanocomposites were examined over a wide voltage range (up to 800 …
Published in Journal of Nanoscience, NanoEngineering & Applications · Vol. 16, Issue 1, 2026 · pp. 22–29 Read article
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Harnessing Deep Learning to Explore Microbial Community Structure and Carbon Storage Capacity in Mangrove Ecosystems: A Framework for Computationally
Abstract: Mangrove ecosystems represent one of the most efficient natural carbon sinks on Earth, functioning as critical blue carbon habitats that sustain diverse microbial communities responsible for biogeochemical cycling and long-term carbon storage. Despite their global ecological significance, accurately quantifying and predicting carbon sequestration in mangrove systems remains challenging due to the complex interactions between microbial diversity, sediment chemistry, and environmental drivers. This study presents a comprehensive and sustainable artificial intelligence …
Published in Research and Reviews : Journal of Computational Biology · Vol. 15, Issue 1, 2026 Read article
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Implement Explainable Machine Learning to Improve Conductivity in Polymer-CNT Nanocomposites: Supporting Adaptive, Flexible, and Long-Lasting IoT Wrap-Around Electronics Applications
Abstract: The rapid growth of Internet of Things (IoT) technologies requires electronic components that are adaptable, lightweight, and durable, and that can continue to function well in diverse contexts and circumstances. Polymer–carbon nanotube (CNT) nanocomposites have become interesting choices for these kinds of uses because they are more flexible, conduct electricity better, and can be made to fit specific needs. However, improving conductivity in these heterogeneous systems remains a major challenge …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 238–254 Read article
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Exploration of Diverse Epoxy-Based Surface Coating Methods for Enhancing Anticorrosion Characteristics
Abstract: Epoxy-based polymers, commonly referred to as polyepoxides, constitute one of the most versatile and widely adopted categories of polymeric materials due to their exceptional structural, mechanical, and chemical characteristics. Their unique macromolecular framework enables strong interfacial bonding, high mechanical stability, and superior resistance to environmental and chemical degradation, positioning them as advanced alternatives to many traditional organic corrosion inhibitors that often fail under prolonged exposure to aggressive conditions When polyepoxides …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 167–177 Read article
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High-Velocity Impact Response of CFRP and Hybrid Composites: A Comprehensive Review on Ballistic Resistance and Damage Mechanisms
Abstract: This review consolidates recent advances in the study of high-velocity impact response of carbon fiber reinforced polymer and hybrid composites. Carbon fiber reinforced polymer composites are widely applied in aerospace, automotive, and defense due to their high strength-to-weight ratio, stiffness, and durability. However, their susceptibility to impact damage such as delamination, matrix cracking, and fiber breakage limits their performance under dynamic loading. To overcome these challenges, researchers have explored reinforcement …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 100–122 Read article
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Utilization of Treated Textile Dyeing Wastewater and GGBFS–Perlite Blends for Sustainable Cementitious Composite Development
Abstract: The increasing global demand for concrete critically intensifies the consumption of potable water, raising significant environmental concerns and depleting vital resources. Concurrently, the textile dyeing industry generates substantial volumes of wastewater, posing considerable disposal and pollution challenges. Our investigation explores a dual solution by utilizing treated textile dyeing wastewater as an alternative mixing water source, combined with ground granulated blast furnace slag (GGBFS) and perlite as supplementary cementitious materials (SCMs), …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 291–300 Read article
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An Overview on MOSFET based Sensor Design
Abstract: In the past two decades the MOSFET has transformed from a simple switch in digital logic to an analog powerhouse that can be cofabricated with the sensing material on a single chip. MetalOxideSemiconductor FieldEffect Transistors (MOSFETs) have silently become the beating heart of modern sensor platforms, translating the faint whispers of physical, chemical, and biological phenomena into robust electrical signatures. This abstract surveys the latest advances that have turned the …
Published in Journal of Microelectronics and Solid State Devices · Vol. 13, Issue 1, 2026 · pp. 20–26 Read article
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Gut Microbial Metabolites in Inflammatory, Metabolic, and Neurologic Disorders.
Abstract: The human gut microbiota transforms dietary and hostderived substrates into a diverse array of metabolites—including shortchain fatty acids (SCFAs), hydrogen sulfide (H₂S), bile acid derivatives, indoles, trimethylamine Noxide (TMAO), branchedchain amino acid (BCAA) derivatives, and lipopolysaccharide (LPS)—that act as key signaling mediators along epithelial, immune, endocrine, and neural axes. These metabolites regulate barrier integrity, energy homeostasis, inflammation, and gut–brain communication and are increasingly implicated in the pathogenesis of inflammatory bowel …
Published in Emerging Trends in Metabolites · Vol. 3, Issue 1, 2026 · pp. 58–64 Read article
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Artificial Intelligence in Entomology: Global Advances, Applications, and Future Directions in Insect Research and Pest Management
Abstract: Artificial Intelligence (AI) is transforming entomology by enabling scalable, data-driven approaches to insect identification, ecological monitoring, and sustainable pest management. This review synthesizes recent global advances in AI applications across taxonomy, behavioral ecology, predictive modeling, and precision agriculture. Machine learning and deep learning techniques—including convolutional neural networks, acoustic classification models, and ensemble predictive algorithms—have demonstrated high classification accuracies (often exceeding 90% under controlled conditions) and improved early detection of pest …
Published in International Journal of Insects · Vol. 3, Issue 1, 2026 · pp. 29–40 Read article