Search
300 articles for “REACTIVE”
-
Negative Pressure Wound Therapy and Intermittent Irrigation with Systemic Antibiotic Suppression followed by One-stage Revision in Delayed Periprosthetic Hip Infection Cases: Reinfection Rate
Abstract: Background: Success rate of one-stage revision remains controversial in patients with delayed periprosthetic joint infection after primary cementless hip arthroplasty. We evaluated the reinfection-free efficacy of negative-pressure wound therapy (NPWT) and intermittent pulsatile irrigation (IPR) using chlorhexidine/povidone iodide combined with systemic antibiotic suppression (SAS) followed by one-stage exchange procedure with NPWT in those patients. Materials and Method: Reinfection rate was assessed in randomly selected forty-two cases (group A) with NPWT-IPR-SAS …
Published in Research and Reviews : Journal of Surgery · Vol. 11, Issue 2, 2022 · pp. 7–15 Read article
-
An Evaluation of Photodynamic Therapy in Dentistry with a Focus on Surgical Applications
Abstract: Throughout the centuries, various forms of light therapy have found applications in medical settings. These include phototherapy for neonatal jaundice, psoralen molecules combined with ultraviolet A light (PUVA) in dermatology, and techniques like photodynamic therapy (PDT) and photodetection. In recent years, the emergence of antibiotic-resistant strains, such as methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus faecalis, has necessitated the exploration of alternative treatment options. Photodynamic antimicrobial chemotherapy (PACT) has arisen as …
Published in Research and Reviews : Journal of Surgery · Vol. 12, Issue 3, 2023 · pp. 1–9 Read article
-
Effects of Chlorpyrifos as Inducer for Oxidative Stress in Liver, Kidney and Spleen of Freshwater Fish, Pseudetroplus maculatus (Bloch, 1795)
Abstract: Chlorpyrifos is one of the most common organophosphate insecticides found abundantly in freshwater ecosystems and has been detected in agricultural and fishery products worldwide. The study focused to determine the effect of chlorpyrifos on the induction of oxidative stress in freshwater fish Pseudetroplus maculatus. Fish were exposed to sublethal concentrations (0.661 and 1.32 μg/l) of chlorpyrifos for 15 and 30 days. Activities of antioxidant enzymes and the levels of hydrogen …
Published in Research and Reviews: A Journal of Toxicology · Vol. 8, Issue 1, 2018 · pp. 20–29 Read article
-
Ameliorating Effect of Vitamin C on Acid Orange 7 Induced Oxidative Stress in the Gill of the Fish, Anabas testudineus (Bloch, 1792)
Abstract: Acid orange 7, an azo dye, was exposed to Anabas testudineus at a sublethal concentration (0.27 g/l) for 24, 72 and 96 h in order to evaluate the antioxidant status in the gill tissue. In addition, vitamin C at 0.55 g/l was exposed for 7 days after the dye exposure. Acid orange 7 decreased the body weight of fish, whereas mucous deposition increased significantly as the first line of defensive …
Published in Research and Reviews: A Journal of Toxicology · Vol. 8, Issue 3, 2018 · pp. 15–27 Read article
-
Evaluation of the antioxidants potential and total phenolic contents of the Albbizia siris a drug plant
Abstract: Free radicals are the major problems of the world today. They are formed endogenously as well as exogenously by different kinds of metabolic processes in the body. Some of them are highly toxic process causing considerable damage to the system and produce several kindsof disorders. Antioxidants are the substance which reduces the formation of free radicals inthe body and are responsible for degradation of free radical and reactive oxygen species …
Published in Research and Reviews: A Journal of Toxicology · Vol. 9, Issue 1, 2019 · pp. 21–25 Read article
-
Arsenic Induced Oxidative Stress and Its Possible Reversal by Chelation Therapy
Abstract: Arsenic (As) is a metalloid listed in group Va of the periodic chart. It exists in nature in the oxidation states +V (arsenate), +III (arsenite), 0 (arsenic) and −III (arsine). In the aqueous environment inorganic arsenic appears commonly in the oxidation states +V and +III as arsenous acid (As (III)), arsenic acid (As (V)), and their salts. Chronic and acute exposures of arsenic leads to cancer, cardiovascular disease (hypertension and …
Published in Research and Reviews: A Journal of Toxicology · Vol. 2, Issue 2, 2012 · pp. 16–37 Read article
-
Mercury-induced Biochemical Changes in Perna viridis Exposed in Chronic Toxicity Test
Abstract: In the present study, the Asian green mussel, Perna viridis, was exposed to 50, 75, 113, 160 and 253 µg/L Hg concentrations under chronic toxicity for the assessment of biochemical biomarkers. Higher levels of glutathione S-transferase (GST), reduced glutathione (GSH), lipid peroxidation (LPO) and lower levels of protein, catalase (CAT) and acetylcholinesterase (AchE) were found. The values were found to be significant at P < 0.01. This study suggests that …
Published in Research and Reviews: A Journal of Toxicology · Vol. 2, Issue 1, 2012 · pp. 15–22 Read article
-
Cadmium Toxicity: Oxidative Stress and Organ Dysfunction
Abstract: Due to continued anthropogenic mobilization, cadmium accumulation in the environment causes various health problems because of its diverse toxic effects, extremely lingering biological half life (20–30 years), low rate of excretion from the body and storage predominantly in soft tissue primarily liver and kidney. Cadmium is known to have numerous noxious effects, including nephrotoxicity, hepatoxicity, osteoporosis, cardiovascular toxicity, lung toxicity, and reproductive toxicity. The biologically significant ionic form of cadmium, …
Published in Research and Reviews: A Journal of Toxicology · Vol. 4, Issue 2, 2014 · pp. 14–31 Read article
-
Gossypetin Inhibits ROS Generation in HeLa and HepG2 Cell Lines
Abstract: Antioxidants are known for their ability to neutralize the reactive oxygen species present within the living system. These antioxidants are mainly secondary metabolites present in plant products and are generally known as nutraceuticals or bioactive compounds. Antioxidant can be categorized into many categories based upon their structure and activities like flavonoids, anthrocyanins and carotenoids. Flavonoids are heterogeneous polyphenolic compounds having beneficiary effect on human body and are also known to …
Published in Research and Reviews: A Journal of Toxicology · Vol. 7, Issue 1, 2017 · pp. 25–31 Read article
-
Carbon Nanoparticles: Occupational Exposure and Genotoxic Effects
Abstract: The field of nanotechnology is revolutionizing today’s era by being the fastest emerging field. Though nanotechnology is the boon to the society, the potential toxicity of these nanoparticles should not be ignored as they can affect anyone from microbes to humans. The main focus of this paper is the toxicity of nanoparticles because people working in these areas, prone to nanoparticles are at high risk due to its toxic property. …
Published in Research and Reviews: A Journal of Toxicology · Vol. 5, Issue 1, 2015 · pp. 9–26 Read article
-
Cadmium and Apoptosis: A Molecular Approach
Abstract: Apoptosis, also known as programmed cell death is a highly regulated and fundamental process found in all multicellular organisms. It is not only implicated in regulatory mechanisms of cells, but has been attributed to a number of diseases, like inflammation, malignancy, autoimmunity and neuro-degeneration. A variability of pollutants can persuade apoptosis. Oncogenic transition metals like cadmium, promote apoptosis alongside DNA base modifications, strand breaks and rearrangements. Generation of reactive oxygen …
Published in Research and Reviews: A Journal of Toxicology · Vol. 6, Issue 1, 2016 · pp. 8–17 Read article
-
Synthesis and Characterization of TiO2 1% SiO2 of Crystal and its Bacterial Applications
Abstract: Three-dimensional (3D) TiO2 Anatase and Rutile structures have attracted much attention due to their optical properties. However, the large band gap of (3.2 eV) results in the fact that anatase TiO2 can act as photo catalyst and be excited by UV light, which only accounts for 3–5% of the solar energy. On considering that nobel metallatic nanomaterials can harvest visible light, in this paper, TiO2 and SiO2 nanocrystals with rod …
Published in Research and Reviews: A Journal of Toxicology · Vol. 10, Issue 1, 2020 · pp. 47–58 Read article
-
Development of Antioxidant Based Therapeutics in Unani System of Medicine
Abstract: During the last decades, several studies have examined the potential role of oxidative stress in the development of various diseases like cancer, Parkinson's disease, Alzheimer's disease, atherosclerosis, myocardial infarction, chronic fatigue syndrome etc. Oxidative stress can cause toxic effects through the production of peroxides and free radicals that damage all components of the cell, including proteins, lipids, and DNA. Unani system of medicine has a wealth of antioxidants that can …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 5, Issue 3, 2018 · pp. 1–4 Read article
-
Phytotherapeutic Potential of Melaleuca: An Integrative Review of Phytochemistry and Antimicrobial, Antifungal, Antioxidant, and Antiviral Mechanisms
Abstract: Melaleuca alternifolia and other species of the Melaleuca genus stand out for the broad spectrum of pharmacological properties attributed to their bioactive compounds, such as monoterpenes, sesquiterpenes, flavonoids, and polyphenols. This study aimed to critically review and analyze scientific evidence produced between 2005 and 2025 regarding the antimicrobial, antifungal, antioxidant, and antiviral activities of Melaleuca, correlating its phytochemistry with molecular mechanisms of action. For this purpose, an integrative literature review …
Published in Research & Reviews : Journal of Herbal Science · Vol. 15, Issue 2, 2026 · pp. 16–30 Read article
-
Digital Therapeutics for Management of Chronic Diseases
Abstract: Digital therapeutics (DTx) mark a major advancement in modern medicine, using advanced software technologies to deliver clinically validated treatments for various physical and mental health conditions. Unlike general wellness apps that focus on fitness or lifestyle tracking, DTx are evidence-based medical interventions developed through rigorous clinical research to ensure safety, efficacy, and measurable outcomes. Delivered via digital platforms such as smartphones, tablets, or specialized medical devices, DTx aim to prevent, …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 15, Issue 2, 2026 Read article
-
MedVerse AI: An Intelligent Digital Health Platform for Patient-Centric Healthcare and Proactive Disease Prediction
Abstract: The rapid digitization of healthcare has led to an unprecedented growth in medical data, ranging from diagnostic images and laboratory reports to electronic health records and clinical notes. Despite this abundance, patients and healthcare providers often struggle to extract meaningful insights due to data complexity and fragmentation. MedVerse AI proposes an intelligent digital health platform that unifies medical image analysis, clinical report interpretation, real-time interaction, and predictive disease analytics into …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 4, Issue 2, 2026 · pp. 1–7 Read article
-
Modern Catalytic Systems: Mechanisms, Materials Engineering, and Sustainable Applications
Abstract: Catalysis is a fundamental pillar of modern chemical science and industrial manufacturing, enabling efficient production of fuels, chemicals, pharmaceuticals, polymers, and environmentally important products through the acceleration of chemical reactions and reduction of activation energy barriers. This review provides a comprehensive overview of contemporary catalytic systems, with emphasis on the relationship between catalyst structure, reaction mechanisms, catalytic performance, and long-term stability. The discussion begins with the classification of homogeneous, heterogeneous, …
Published in Journal of Catalyst & Catalysis · Vol. 13, Issue 2, 2026 · pp. 01–09 Read article
-
AI-Driven IoT Ecosystems for Real-Time Thermo-Chemical Decision Making
Abstract: The efficient management of thermo-chemical processes is a critical challenge in modern industry, where maintaining precision, operational safety, and energy efficiency directly influences productivity and sustainability. The convergence of the Internet of Things (IoT) and Artificial Intelligence (AI) has transformed conventional industrial systems into intelligent, data-driven environments capable of continuous monitoring, predictive analysis, and autonomous decision-making. By integrating interconnected sensors, edge computing, cloud platforms, and advanced machine learning algorithms, industries …
Published in International Journal of Photochemistry and Photochemical Research · Vol. 4, Issue 2, 2026 · pp. 10–15 Read article
-
Molecular Characterization of Respiratory Viral Infections and Co-Infections in Pediatric Patients Using FilmArray™ Multiplex PCR in a Tertiary-Care Hospital, South India
Abstract: Respiratory tract infections (RTIs) are a major cause of pediatric morbidity worldwide, with viruses, such as respiratory syncytial virus, rhinovirus/enterovirus, influenza virus, adenovirus, and parainfluenza virus, contribute significantly to hospitalizations. Conventional diagnostic methods often require prolonged processing times, which can delay clinical decision-making. Rapid molecular platforms, such as the FilmArray™ Panels, offer timely and comprehensive pathogen identification. This study aimed to evaluate the prevalence, seasonal trends, and co-infection patterns of …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 16, Issue 2, 2026 · pp. 57–66 Read article
-
Harnessing the Bioactive Potential of Calotropis gigantea and Calotropis procera
Abstract: The medicinal plants of the Apocynaceae family Calotropis gigantea and Calotropis procera have gained more and more interest as source of bioactive molecules for biomedical applications like cancer therapy. They have various pharmacological activities, which are believed to be linked to various phytochemical constituents such as cardenolides, cardiac glycosides, flavonoids, triterpenoids, steroids, phenolic compounds, alkaloids, and proteins in their latex. The recent molecular and cellular studies show that extracts and …
Published in International Journal of Molecular Biotechnological Research · Vol. 4, Issue 2, 2026 Read article