All articles
41 articles
-
Artificial Intelligence in Microbiological Research: Methods, Applications and Implications
Abstract: Artificial Intelligence (AI) is revolutionising microbiological research by enabling the rapid analysis of complex biological data and improving the accuracy, efficiency, and reliability of scientific investigations. Recent advances in machine learning, deep learning, and bioinformatics have transformed AI into a powerful tool for studying microorganisms, their genetic composition, evolutionary patterns, and interactions with hosts and the environment. AI-driven computational models can process large and complex datasets far more efficiently than …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 16, Issue 2, 2026 Read article
-
Enhancing Fiber Digestibility in Dairy Cows: Influence of Dietary, Management, and Environmental Factors
Abstract: The digestibility of fiber in dairy cows is a critical factor for optimizing their nutritional efficiency and overall productivity. This study explores the key dietary, management, and environmental factors influencing fiber digestibility in the rumen. Various aspects of feed composition, such as fiber content, protein-to-fiber ratio, and the presence of anti-nutritional factors, play a significant role in determining microbial activity and rumen fermentation efficiency. Physical feed characteristics, including particle size, …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 16, Issue 2, 2026 Read article
-
India’s Pioneering Advancements in Vaccinology: Challenges and Milestones – Part 2
Abstract: India has become a global leader in vaccinology, playing a vital role in developing, producing, and distributing vaccines that protect millions of lives. By embracing advances in molecular immunology, recombinant antigen technology, and virus-like particle (VLP) platforms, the country has created affordable vaccines against major diseases, including poliovirus, rotavirus, and SARS-CoV-2. National initiatives, like Mission Indradhanush and Vaccine Maitri, have helped expand immunization coverage, improve public health, and share vaccines …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 16, Issue 2, 2026 Read article
-
Effectiveness of Alcohol-Based Hand Rubs in Glove Hygiene: A Meta-Analysis and Systematic Review
Abstract: Introduction: Hand hygiene is crucial for preventing hospital-acquired infections, though gloves have been reported to curb the spread of infection, but they have their limitation. While recommended for specific procedures, they don't guarantee complete protection and frequent changes are resource limiting. This study investigates the potential of alcohol-based hand rubs (ABHR) for disinfecting gloves worn by healthcare workers (HCWs). Methodology: We conducted a meta-analysis searching six databases for studies on …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 16, Issue 1, 2026 · pp. 33–45 Read article
-
Vaccines Through Time: Conventional Foundations and Next-Gen Innovations–Part 1
Abstract: Vaccination serves as a critical pillar of global public health, markedly decreasing infection rates and associated mortality. Traditional vaccine platforms such as live attenuated, inactivated, toxoid, and subunit vaccines have demonstrated effectiveness against pathogens like Mycobacterium tuberculosis and Plasmodium spp., yet they are constrained by antigenic variability, limited immune persistence, and complex production processes. Breakthroughs in synthetic biology, structural antigen design, and computational vaccinology have driven the development of advanced …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 16, Issue 1, 2026 · pp. 53–70 Read article
-
Genetic Detection of Hepatitis C -Virus and Occult Hepatitis B in Patients from Al-Najaf Al-Ashraf Governorate, Iraq.
Abstract: Recently, a noticeable increase in the prevalence of occult Hepatitis B virus (HBV) and Hepatitis C virus (HCV) infections has been observed among clinical cases such as patients undergoing hemodialysis, blood transfusion, liver diseases, and thalassemia worldwide. To limit and control this spread, the present study was conducted to investigate and detect the molecular presence of HCV and occult HBV using the Nested PCR technique, as well as to observe …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 16, Issue 1, 2026 Read article
-
Preparation of Vitamin B12-Enriched Curds: A Novel Approach to Address Nutritional Deficiency in Vegetarian Populations
Abstract: Addressing the significant public health challenge of Vitamin B12 deficiency, particularly within India’s substantial vegetarian population (estimated at 35%), this study explored biofortification of the widely consumed dairy product curd (dahi) as a culturally acceptable solution, overcoming barriers of cost, access, and compliance associated with traditional supplements. Researchers isolated bacterial strains from Swiss cheese, presumptively identified as Propionibacterium shermanii based on phenotypic characteristics, and used them to ferment curd under …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 16, Issue 1, 2026 · pp. 1–15 Read article
-
Unlocking Novel Drug Targets and Therapeutic Advancements Against RNA Viruses: Insights from HMPV and SARS-CoV-2
Abstract: Re-emerging RNA viruses pose a significant epidemiological welfare threat due to their high mutation rates, potential for zoonotic transmission, and capacity to cause widespread outbreaks such as Human Metapneumovirus (HMPV), Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), Influenza, etc. The rapid evolution and re-emergence of these viruses necessitate the development of novel drug targets and therapeutic strategies to combat existing and future outbreaks. This study focuses on structural as well …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 15, Issue 3, 2025 · pp. 54–86 Read article
-
Microbial Competition in the Rumen: Insights into Fermentation Kinetics, Host Health, and Environmental Sustainability
Abstract: Microbial competition within the rumen is a crucial determinant of fermentation efficiency, nutrient utilization, and overall host health in ruminant animals. The complex microbial community in the rumen comprises bacteria, protozoa, fungi, and archaea, all of which interact in intricate and often competitive ways to degrade feed and produce essential metabolites. This competition significantly influences fermentation kinetics, determining the rate and efficiency of carbohydrate, protein, and fat breakdown. Such microbial …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 15, Issue 3, 2025 · pp. 27–42 Read article
-
Forage Bioactive Compounds and Rumen Microbiota: Exploring Colonization, Density, and Diversity Dynamics in Dairy Cows
Abstract: The rumen microbiota plays a pivotal role in the health, productivity, and sustainability of dairy cows, with forage serving as a fundamental dietary component influencing microbial dynamics. This review explores the intricate interactions between forage bioactive compounds – such as tannins, saponins, alkaloids, and flavonoids – and the rumen microbiota, focusing on their effects on colonization, microbial density, and diversity. Forage bioactives modulate microbial adhesion, biofilm formation, and growth patterns, …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 15, Issue 3, 2025 · pp. 15–26 Read article
-
Patterns and Variations in Complementary Feeding Practices Among Mothers of Children Aged 6–24 Months Attending Immunization Clinics in Mandi Gobindgarh, Punjab, India
Abstract: Introduction: Complementary feeding introduces solid or semisolid foods to an infant’s diet while breastfeeding. In India, feeding infants and young children is determined by their socioeconomic status, cultural practices, and healthcare access. The study assesses the feeding practices of mothers with children aged 6–24 months who come for immunization at Mandi Gobindgarh, Punjab. Methods: A cross-sectional study was conducted with 350 mothers selected through systematic random sampling. A structured questionnaire …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 15, Issue 3, 2025 · pp. 43–53 Read article
-
An Overview of Microbial Diversity in the Functions of Wetland Ecosystems
Abstract: Wetlands serve as abundant reservoirs of biodiversity, crucial for the well-being of both humanity and the natural world. They represent the most critical and fertile ecosystem, where water predominantly dictates the environment and the plant and animal species that inhabit it. Wetlands have diverse microbial flora and fauna, which play essential roles in ecosystems. Soil and aquatic microorganisms mediate many processes, such as biogeochemical cycles, waste decomposition, symbiotic relationships, and …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 15, Issue 3, 2025 · pp. 1–14 Read article
-
Extended-spectrum beta-lactamases (ESBLs) and Metallo-beta-lactamases (MBLs): A Review
Abstract: Gram-negative bacteria produce extended-spectrum beta-lactamases (ESBLs) and metallo-beta-lactamases (MBLs), enzymes that play a crucial role in antibiotic resistance. These enzymes enable the bacteria to withstand a wide array of beta-lactam antibiotics, including penicillins, cephalosporins, and carbapenems. The production of these enzymes, particularly by organisms, such as Escherichia coli and Klebsiella pneumoniae, complicates treatment options for severe infections, leading to increased morbidity and mortality in clinical settings. ESBLs are primarily responsible …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 15, Issue 2, 2025 · pp. 8–19 Read article
-
HIV/TB Co-Ordination Program - An Integration in Highly Epidemic Provinces
Abstract: Tuberculosis is the commonest co-infection among PLHA (HIV/AIDS). An appropriate measure for controlling TB spread in community of high TB/HIV burden state that requires intervention strategies against this dual epidemic which include intensified case finding at ART centers, involvement of health care delivery system, and Non-Government Organizations for early detection of TB and HIV, counselling and support, provision of daily patient’s weight band-wise FDD, ATT for TB, cotrimoxazole preventive/ prophylaxis …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 15, Issue 2, 2025 · pp. 20–26 Read article
-
Practical Strategies to Mitigate Acidosis in Dairy Cattle: Implications of Nutritional, Genetic, and Management Practices
Abstract: Acidosis in dairy cattle remains a critical concern, adversely affecting rumen health, milk production, and overall animal welfare. This study investigates practical strategies to mitigate acidosis through integrated nutritional, genetic, and management approaches. Nutritional strategies emphasize balancing forage-to-concentrate ratios, providing adequate fiber, and utilizing feed additives such as buffers, probiotics, and yeast cultures to stabilize rumen pH. The importance of gradual dietary transitions and monitoring total mixed ration (TMR) composition …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 15, Issue 2, 2025 · pp. 27–44 Read article
-
Risk Factors Associated with Subclinical Mastitis in Dairy Cows: Implications for Microbial Dynamics, Environmental Influences, and Management Factors
Abstract: Subclinical mastitis is a prevalent yet often overlooked condition in dairy cows, leading to reduced milk yield and quality. This study examines the microbial dynamics, environmental influences, and management factors contributing to subclinical mastitis in dairy herds. Microbial agents, including bacteria such as Staphylococcus aureus, Escherichia coli, and Streptococcus uberis, are key contributors, with their ability to persist and form biofilms complicating detection and treatment. Environmental factors, including bedding quality, …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 15, Issue 2, 2025 · pp. 45–61 Read article
-
Excoecaria agallocha Extract from Leaves Encounters Antifungal, Antibacterial, and Cytotoxic Activity – In Vitro Studies
Abstract: Mangroves contain a wide range of bioactive substances, certain of and these have been used as solutions for a variation of conditions for thousands of years. Excoecaria agallocha leaf application components have been extracted in the presence of organic solvents along with water-based with a Soxhlet apparatus and antibacterial research properties employing diffusion agar well assays towards nine different kinds of culture infectious agents, six clinical trials isolated compounds, as …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 15, Issue 2, 2025 · pp. 1–7 Read article
-
Host-Microbiota Crosstalk in the Rumen: Signaling Pathways for Nutrient Metabolism and Disease Resilience in Dairy Cows
Abstract: The rumen serves as a highly intricate microbial ecosystem, fundamentally responsible for the degradation of fibrous plant materials in ruminant. The intricate host-microbiota crosstalk within the rumen significantly influences nutrient metabolism, growth, and health outcomes in livestock. The interaction between the host and its microbial community, mediated through signaling pathways including the production of short-chain fatty acids (SCFAs), bile acids, and various metabolites, is crucial for enhancing nutrient absorption, fermentation …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 15, Issue 1, 2025 · pp. 29–41 Read article
-
Plant-Derived Vaccines: A Sustainable Approach to Disease Control for Global Health
Abstract: Plant-based vaccines present a novel and environmentally responsible approach to vaccination, with significant potential for improving both human and animal health. These vaccines are safer and less expensive than traditional vaccine manufacturing methods because they use genetically modified plants to create antigens that elicit an immune response. Plant-based systems offer a potential remedy for traditional vaccines' high production costs and environmental impact, which are growing problems. Plant-derived vaccines have shown …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 15, Issue 1, 2025 · pp. 17–20 Read article
-
Comparison of a Human Papillomavirus Test with the Hybrid Capture 2 and a Real-Time PCR Method for 18 High-Risk and Low-Risk Human Papillomavirus Infections in Women
Abstract: Squamous intraepithelial lesions (SILs), which are a kind of cancer, and HUMAN papillomavirus (HPV) viral load have frequently been investigated as a risk factor in findings that were in dispute. These studies made use of several HPV viral quantitation assays [including the commercially available hybrid capture 2 (HC2) assays], which vary in their capacity to consider variations in cervical cell collection, linear dynamic range of viral load quantitation, and identified …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 15, Issue 1, 2025 · pp. 10–16 Read article