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2602 articles
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Quantifying Damage Evolution in Fiber-reinforced Composites Using Fracture Mechanics
Abstract: By evaluating the evolution of damage, such as cracks or delamination, within the material over time or under various loading situations, damage evolution in fiber-reinforced composites can be characterized using fracture mechanics. Fracture mechanics offers a framework for understanding and projecting the behavior of materials that already have damage or flaws. Since they have a high strength-to-weight ratio and unique mechanical qualities, fiber-reinforced composites are essential in many branches of …
Published in International Journal of Fracture Mechanics and Damage Science · Vol. 1, Issue 1, 2023 · pp. 26–32 Read article
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Crack Propagation Analysis in Metallic Alloys: A Comparative Study of Traditional and Advanced Materials
Abstract: A vital component of materials science and engineering, crack propagation analysis is essential to determining the structural integrity and dependability of materials. Designing safe and long-lasting structures for a variety of sectors required an understanding of how cracks begin, spread, and interact with a material's microstructure. To guarantee the performance, safety, and dependability of materials in a variety of applications, crack propagation analysis is essential. It offers insightful information about …
Published in International Journal of Fracture Mechanics and Damage Science · Vol. 1, Issue 1, 2023 · pp. 33–41 Read article
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Problems and Difficulties in the Additive Manufacturing of Composites with Carbon Fiber Reinforcement for Medical Application
Abstract: Amputation is more prevalent than one may think due to an accident, war, or disease. Prosthetics and associated orthotics have a combined global market value of $2.8 billion. Carbon fibre has found a market due to increased demand for foot prostheses. Fused deposition modeling (FDM) is a rapidly advancing three-dimensional (3D) printing technique. PEEK (polyether-ether-ketone) is a biocompatible, high-performance polymer that could potentially be utilised as an orthopedic surgery implant …
Published in International Journal of Fracture Mechanics and Damage Science · Vol. 1, Issue 1, 2023 · pp. 8–12 Read article
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Analyzing the Sheet Metal Extrusion Process Using Finite Element Analysis
Abstract: A wide range of sheet metal forming techniques has been developed to make it easier to produce intricate 3D objects. However, the knowledge still isn't sufficient. The sheet metal extrusion method was examined in this research as one of the common sheet-bulk metal manufacturing technologies. Consideration of the flow-stress curve's impact across a broad range of plastic strain and ductile damage played a pivotal role in constructing a realistic finite …
Published in International Journal of Fracture Mechanics and Damage Science · Vol. 1, Issue 1, 2023 · pp. 13–25 Read article
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Effect of WEDM Machining Parameter on the MMC: A Review
Abstract: Recent area of manufacturing is highly focus on good accuracy and a complex shapes are mechanized by the advanced machining operation. The wire electrical discharge machining (WEDM) have the ability to produce the complex shapes with having high accuracy. The WEDM is non-contact type machining operation and is used for metal materials as well as Metal Matrix Composites (MMCs), ceramics composites those have many application in vast areas such as …
Published in International Journal of Fracture Mechanics and Damage Science · Vol. 1, Issue 1, 2023 · pp. 1–7 Read article
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A review on antibacterial properties of eucalyptus oil and different eucalyptus species used in pharmaceuticals
Abstract: Medicinal plants with antimicrobial compounds play a crucial role in combating various pathogens. Eucalyptus, belonging to the myrtle family, is notable for its diverse antimicrobial compounds. This fast-growing plant thrives in many countries and its various parts offer significant medicinal value, including timber, pulpwood, and essential oils. The leaves, often considered forest harvesting waste, contain essential oils with potential medicinal benefits. Members of the genus Eucalyptus are highly valued for …
Published in International Journal of Antibiotics · Vol. 1, Issue 2, 2024 · pp. 10–19 Read article
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Optimizing Antibiotic Analysis: A Comprehensive Guide to HPLC Process of Assessment and Quantification
Abstract: The history and uses of chromatography are thoroughly covered in this work, with an emphasis on the use of High-Pressure Liquid Chromatography (HPLC) in pharmaceutical analysis. Since its discovery by Russian botanist Mikhail Tswett in the 19th century, chromatography has undergone tremendous developments that have given rise to a variety of chromatography types and applications. The story follows the evolution historically, emphasizing Tswett's groundbreaking breakthrough in plant color classification and …
Published in International Journal of Antibiotics · Vol. 1, Issue 2, 2024 · pp. 27–44 Read article
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Evaluation of Prescribing Pattern of Drugs in Hemodialysis Patients
Abstract: Background: Patients undergoing hemodialysis often exhibit a high level of dependency and frequently present with multiple co-morbid conditions Chronic kidney disease (CKD) poses a significant global public health challenge, with its association with numerous complications. Prescribing medications appropriately for individuals with CKD presents a substantial challenge. Objective: The study aimed to assess the prescribing patterns of drugs in hemodialysis patients. Results: Out of the total 82 selected patients, 42 (51%) …
Published in International Journal of Antibiotics · Vol. 1, Issue 2, 2024 · pp. 20–26 Read article
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Assessment of Finerenone Safety and Efficacy in Individuals with Type 2 Diabetes and Chronic Kidney Disease
Abstract: Background: In this work, we provide strong evidence for the safety and efficacy of finerenone in people with type 2 diabetes and chronic kidney disease. Our goal is to improve patients' quality of life and general well-being through our research. Aim: Finerenone exhibited a significant decrease in the likelihood of renal and cardiovascular (CV) events in individuals with both type 2 diabetes and chronic kidney disease. This exploratory subgroup analysis …
Published in International Journal of Antibiotics · Vol. 1, Issue 2, 2024 · pp. 06–09 Read article
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Antibiotics – Challenges in our Post-COVID Era
Abstract: Accidental discovery of the antibiotic properties of penicillin marked a watershed moment in healthcare, transforming the landscape of medicine and saving countless lives of injured and infected. Further research and awareness on the advantages of this “miracle drug” resulted in its bulk production in the 1940s, and played a crucial role in saving lives of thousands during World War II. Subsequent discoveries especially broad-spectrum antibiotics paved the way for further …
Published in International Journal of Antibiotics · Vol. 1, Issue 2, 2024 · pp. 1–5 Read article
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Pharmacophore mapping, 3D QSAR, docking, and ADME prediction studies of novel Benzothiazinone derivatives
Abstract: Background Tuberculosis is a major public health concern worldwide which is caused by Mycobacterium tuberculosis. DprE1 (Decaprenyl Phosphoryl Ribose 2’- Epimerase) is the most challenging target for development of novel anti- tubercular agents because it is a small protein and located into cytoplasmic membrane. So, novel anti-TB drugs did not bound effectively with it. DprE1 catalyzes the oxidation of the 2’ hydroxyl group of DPR (Decaprenyl Phosphoryl D- Ribose) …
Published in International Journal of Antibiotics · Vol. 1, Issue 1, 2024 · pp. 59–82 Read article
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Blockchain and Smart Contract Based Decentralized Rental Platform
Abstract: The advent of blockchain technology has emerged as a revolutionary influence in contemporary society, restructuring engagements and commerce. It is characterized by a decentralized and distributed network of blocks storing information with digital signatures. Initially developed for digital cryptocurrencies like Bitcoin and Ethereum, blockchain has expanded its utility across various domains, leveraging its core features of decentralization, persistency, anonymity, and auditability. Originally designed for cryptocurrencies, blockchain technology has extended its …
Published in International Journal of Data Structure Studies · Vol. 1, Issue 2, 2023 · pp. 18–24 Read article
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Grid based docking study of some 2-(4-methylsulfonyl phenyl) pyrimidine derivatives (designed after QSAR studies) with Cyclooxygenase
Abstract: Molecular docking helps in studying drug/ligand or receptor/ protein interactions by identifying the suitable active sites in protein, obtaining the best geometry of ligand-receptor complex and calculating the energy of interaction for different ligands to design more effective ligands. In Grid based docking, after unique conformers of the ligand are generated, the receptor cavity of interest is chosen and a grid is generated around the cavity. Cavity points are found …
Published in International Journal of Antibiotics · Vol. 1, Issue 1, 2024 · pp. 23–41 Read article
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“DEVELOPMENT AND CHARACTERIZATION OF PHYTOSOMES FOR THE TREATMENT OF ANTI-CANCER ACTIVITY BY USING THE Spirulina (Arthospira Plantesis) EXTRACT”
Abstract: This study aims to investigate and evaluate spirulina's anticancer properties.The current research is centred on obtaining a Spirulina-containing drug. The goal is to design and create Phytosomes, characterizing them based on relevant and crucial parameters. The process of solvent evaporation was utilized in the creation of Phytosomes. Various parameters such as zeta potential, particle size, infra-red spectral analysis, % drug content, encapsulation efficiency, and % drug release (% DR) were …
Published in International Journal of Antibiotics · Vol. 1, Issue 1, 2024 · pp. 10–22 Read article
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Environmental implications of Chitosan nanostructures.
Abstract: Chitosan (CS), as a biopolymer, has unrivalled chemical and mechanical modification capabilities to develop novel characteristics, functions, and applications, particularly in the manufacture of cutting-edge membrane adsorbents. Membrane adsorbents utilizing carbon starch (CS) have emerged as a viable and efficient engineering instrument for eliminating diverse pollutants from aquatic settings, including heavy metals and dyes. To date, much study has been directed towards improving the adsorptive characteristics, permeability, physicochemical stability, and …
Published in International Journal of Antibiotics · Vol. 1, Issue 1, 2024 · pp. 42–58 Read article
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A Concurrent Estimation of Phytoconstituents Piperine, Quercetin and Kaempferol Present in Siddha Polyherbal Formulation Kabasara Kudineer by Rp-Hplc
Abstract: A straightforward, accurate, and precise technique was developed and validated for the simultaneous determination of Quercetin, Kaempferol, and Piperine in the polyherbal formulation Kabasura Kudineer. The sample was chromatographed using a C18 column (150x4.6mm, 5u) with a mobile phase composed of Acetonitrile and Ortho phosphoric acid in a 45:55 ratio, flowing through the column at a rate of 1ml/min. The detection wavelength for Quercetin, Kaempferol, and Piperine was set at …
Published in International Journal of Antibiotics · Vol. 1, Issue 1, 2024 · pp. 1–9 Read article
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Configuring Connectivity: Cisco Packet Tracer DHCP Server Best Practices
Abstract: In internet protocol (IP) networks, the dynamic host configuration protocol, or DHCP, is a network administration protocol that uses an architecture based on clients and servers to dynamically allocate internet protocol (IP) addresses and other interface characteristics to devices that are connected to the network. It explains routing between the ISP and the campus router uses a static route between the ISP and the gateway, and a default route between …
Published in International Journal of Satellite Remote Sensing · Vol. 1, Issue 1, 2023 · pp. 29–35 Read article
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Social Capital as a Predicting Indicator to Measure the Psychological Health Impacts of COVID-19 Pandemic on Urban Societies in Pakistan.
Abstract: The COVID-19 pandemic has forced people to adapt to massive changes in their lifestyles; from health to work and how they interact with everyone nearby they know. This study aims to investigate the psychological wellbeing-impacts of COVID-19 on social capital in Pakistan. Social capital means the social and cultural coherence (as a predicting indicator) in the society. This was a survey based study conducted in 5 major cities (Islamabad, Rawalpindi, …
Published in International Journal of Urban Design and Development · Vol. 2, Issue 1, 2024 · pp. 12–21 Read article
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The Role of Automation in Modernizing Irrigation Practices and Smart Farming: A Comprehensive Review
Abstract: The development of a "Smart Farming Using Automation" system that functions in three modes—timer, soil moisture, and PH sensor—for the farmer's advantage is the focus of this study. An automated drip irrigation system with a PLC is described in this paper. Using sensors for soil moisture and pH. The soil moisture sensor's function is to calculate how much water is required for irrigation. A PLC uses the solenoid valve to …
Published in International Journal of Electrical Machine Analysis and Design · Vol. 1, Issue 1, 2023 · pp. 36–42 Read article
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Challenges faced by upper indus basin (UIB) communities due to climate change
Abstract: The Upper Indus Basin (UIB) communities are heavily dependent on water resources for their sustenance. The region relies on glacial and snowmelts for irrigation water, energy, domestic and irrigation uses. Climate change poses threat to vulnerable region all around the world, and Upper Indus Basin (UIB) is no different. The variability in climatic conditions such change in precipitation pattern and temperature fluctuations have disrupted the agriculture practices of the region …
Published in International Journal of Environmental Planning and Development Architecture · Vol. 2, Issue 1, 2024 · pp. 11–20 Read article